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8941
Long-chain chlorinated paraffins (LCCPs) exposure induces apoptosis in primary chicken embryo hepatocytes through oxidative stress
Published 2025-01-01“…Our findings indicate that the proliferation capacity of primary chicken embryo hepatocytes exposed to LCCPs at concentrations of 1, 10, and 100 μg/L was significantly diminished, with an observed arrest in the G0/G1 phase and a notable reduction in the proportion of cells in the G2/M phase. Additionally, we observed that LCCPs exposure markedly decreased the autophagy levels in primary chicken embryo hepatocytes while significantly increase the levels of apoptosis. …”
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8942
THrombosis AETiology of Aviation-Related Travel: The THETA θ study
Published 2024-09-01“…Healthy volunteers aged ≥18 years (N=40), without risk factors for venous thromboembolism, were exposed to an exacerbated altitude of 18 000 feet (5 486 m) for 1 hour. During the flight, the oxygen (O2) levels of the participants, who received supplemental O2, were measured by pulse oximetry and maintained at >92%. …”
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8943
Mapping forest-agroforest frontiers in the Peruvian Amazon with deep learning and PlanetScope satellite data
Published 2025-05-01“…To achieve this, we combine deep learning and remote sensing data, including 3-m PlanetScope satellite imagery, a Digital Elevation Model (DEM), and temporal data from the Landtrendr change detection algorithm. …”
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8944
Performance augmentation of triangular solar still using sensible energy storage materials: thermo-exergo-economic and sustainability analyses
Published 2024-12-01“…From experimental results, it was observed that the daily yield of the TSS-S was 3.12 L/m2, which is about 81.40% higher than that of TSS. …”
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8945
Bicyclic peptide-enhanced covalent inhibitor of SARS-CoV-2 3CL protease
Published 2024-10-01“…The most potent bicyclic peptide can inhibit the target with a half-maximal inhibitory concentration (IC50) of 40.46 ± 6.35 nM. Mass spectrometry tests confirmed the covalent inhibition of the target protease by the developed peptides. …”
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8946
Pressure-driven polymeric membrane performance prediction, new membrane dimensionless number, and considerations for effective membrane design, selection, testing, and operation
Published 2025-02-01“…The model integrates solvent densities (ρi), solubility parameters of the membrane (δM), solute (δSo), solvent (δSv), and the extent of membrane constraint (ϕ). …”
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8947
Valores de referencia para TSH y T4 libre en la población de Medellín, Colombia
Published 2025-01-01“…Resultados: se encontró que, en la población sana de la ciudad de Medellín, los valores de TSH oscilaron entre 0,49 y 5,72 mUI/l y para T4L entre 0,65 y 1,19 ng/dl. Conclusiones: para una población entre los 10 y 65 años, de la ciudad de Medellín, los valores mencionados previamente en los resultados no presentaron diferencias estadísticamente significativas por edad o sexo. …”
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8948
Endoplasmic reticulum stress-related super enhancer promotes epithelial-mesenchymal transformation in hepatocellular carcinoma through CREB5 mediated activation of TNC
Published 2025-02-01“…Analyses of TCGA datasets and tissue arrays showed that CREB5 mRNA and protein expression levels were higher in liver cancer tissues than in paired normal tissues. …”
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8949
Multi-layered electrospun grafts for surgical repair: Biomimicking physiological ascending aortic compliance
Published 2025-01-01“…G 3 , which combined electrospinning with a stable silicone-coated inlay was chosen for the fabrication of medical grade thermoplastic polyurethane grafts (G m ; n = 6). Dynamic compliance values of 19.68 ± 11.5%/100 mmHg (50–90 mmHg), 15.18 ± 8.7%/100 mmHg (80–120 mmHg) and 14.56 ± 7.4%/100 mmHg (110–150 mmHg) were achieved. …”
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8950
Lack of evidence for Mycoplasma spp. in bulk tank milk of herds located in mid-western Colombia
Published 2022-01-01“…El promedio del LnSCC fue de 6.19 x103 células/ mL, Mycoplasma spp. no fue aislado de los cultivos microbiológicos y no se encontró ADN de a esta especie mediante PCR en los 220 tanques de leche. …”
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8951
Influence of day and night temperature and carbon dioxide concentration on growth, yield, and quality of green butterhead and red oakleaf lettuce.
Published 2025-01-01“…Green butterhead 'Rex' and red oakleaf 'Rouxaï RZ' seedlings were transplanted into hydroponic tanks under a photosynthetic photon flux density of 300 μmol·m‒2·s‒1 for 17-h·d‒1. CO2 concentrations of 500, 800, or 1200 μmol·mol-1 and day/night and MDT setpoints of 22/15°C (MDT 20°C), 25/18°C (23°C), or 28/21°C (26°C) were maintained within growth chambers. …”
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8952
RETRACTED: Efficacy of Vanadyl Sulfate and Selenium Tetrachloride as Anti-Diabetic Agents against Hyperglycemia and Oxidative Stress Induced by Diabetes Mellitus in Male Rats
Published 2021-12-01“…Fifty male albino rats were divided into five groups, and all treatments were administrated at 9:00 a.m. daily for 60 successive days: control, STZ (Streptozotocin; 50 mg/kg of STZ was given to 6 h fasted animals in a single dose, followed by confirmation of diabetic state occurrence after 72 h by blood glucose estimation at >280 mg/dl), STZ (Diabetic) plus administration of VOSO<sub>4</sub> (15 mg/kg) for 60 days, STZ (Diabetic) plus administration of selenium tetrachloride (0.87 mg/Kg), and STZ plus VOSO<sub>4</sub> and, after 1/2 h, administration of selenium tetrachloride at the above doses. …”
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8953
Awareness and Attitudes of Medical Students, Interns, and Residents Toward Telemedicine in Medical Education During the COVID-19 Pandemic: Survey-Based Cross-Sectional Study From...
Published 2025-02-01“…The mean score for participants’ attitudes was above 3 ( M = 3.78, SD = 0.24) indicating a generally favorable view of telemedicine. …”
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8954
Segmentasi Wilayah Terdampak Bencana Berdasarkan Fitur Geo-Posisi
Published 2024-08-01“…Pada penelitian ini, simulasi DAS-Apps dilakukan menggunakan dataset gempa (M ≥ 5.0) yang berasal dari Badan Meteorologi, Klimatologi, dan Geofisika (BMKG) pada rentang bulan November dan Desember 2022 khusunya data bencana gempa bumi untuk wilayah Cianjur, Indonesia. …”
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8955
Resetting the Hsc70-mediated lysosomal degradation of PD-L1 via a supramolecular meso peptide for the restoration of acquired anti-tumor T cell immunity
Published 2025-02-01“…Furthermore, based on bioinformatics analysis of mRNA expression data from 30 types of tumors obtained from TCGA database, malignant melanoma was identified as the most suitable indication for CTAC-PDL1 due to its specific characteristics of tumor immune. …”
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8956
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8957
NT5E (CD73) as a prognostic biomarker and therapeutic target associated with immune infiltration in lung adenocarcinoma
Published 2025-02-01“…We found that NT5E was significantly overexpressed at both the mRNA and protein levels in LUAD tissues. Elevated NT5E expression was significantly linked to multiple clinicopathological factors, including metastasis and pathological stage, and served as a strong predictor of poor prognosis in LUAD patients. …”
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8958
Suppression Efficiency for Dust from an Iron Ore Pile Using a Conventional Sprinkler and a Water Mist Generator
Published 2022-01-01“…Herein, the optimal operating parameters for maximum dust suppression efficiencies through a water mist generator and a conventional sprinkler for particulate matter (PM) originating from an iron ore pile measuring about 2 m in height and with a stacking angle of about 30° are investigated. …”
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8959
Comprehensive analysis of proteomic and biochemical responses of Daphnia magna to short-term exposure to polystyrene microplastic particles
Published 2025-01-01“…To investigate the immediate molecular impacts of MP exposure, we exposed Daphnia magna, a keystone species in freshwater ecosystems, to polystyrene microplastic particles (5 μm, 5 μg/L) for 48 h. Through proteomic and biochemical analyses, we identified extensive disruptions in key physiological pathways. …”
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8960
Development and evaluation of a novel E7 multi-epitopic vaccine for human papillomavirus type 16: design, expression, purification, and immunological characterization
Published 2025-02-01“…Among the tested solubilization buffers, the buffer with a pH of 12 and containing 2 M urea showed the highest solubilization effect. …”
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