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  1. 5721

    Bioinformatics insights into mitochondrial and immune gene regulation in Alzheimer's disease by Tian Meng, Yazhou Zhang, Yuan Ye, Hui Li, Yongsheng He

    Published 2025-02-01
    “…Moreover, qRT-PCR validation confirmed that the mRNA expression of the five biomarkers was consistent with bioinformatics results. …”
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  2. 5722

    Saussurea gossypiphora extracts reduce inflammation by reversing inflammatory cytokine levels in in-vitro and in-vivo by Kalyani Jatoth, Pawan Kumar Anoor, Ramesh Kande, Sandeepta Burgula

    Published 2025-02-01
    “…Results: The analysis of GC–MS of MESGD revealed the presence of various bio-active components such as Spirohexane-1-Carboxylic acid, ethyl ester; 1-Methyl-1-n-decycloxy-1-silacyclobutane; 1, 2, 4-Trioxolane-2-octanoic acid, 5-octyl, methyl ester; DPPH assay showed inhibition of free radicals by 40 - 95.66 % in the range of 25 – 1000 µg/mL concentrations, comparable with Ascorbic acid. …”
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  3. 5723

    The effect of depth data and upper limb impairment on lightweight monocular RGB human pose estimation models by Gloria-Edith Boudreault-Morales, Cesar Marquez-Chin, Xilin Liu, José Zariffa

    Published 2025-02-01
    “…The models were trained, validated and tested using the CMU Panoptic and Human3.6 M data sets as well as a custom data set. The custom data set includes RGB-D and optical motion capture data of 15 uninjured and 12 post-stroke individuals, while they performed movements involving their upper limbs. …”
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  4. 5724

    Inhibition of complement system-related gene ITGB2 attenuates epithelial–mesenchymal transition and inflammation in diabetic nephropathy by Jun Peng, Wenqi Zhao, Lu Zhou, Kun Ding

    Published 2025-02-01
    “…Also, VWF and ITGB2 were significantly related to the clinical features, including age, serum creatinine level, and GFR (MDRD). Besides, mRNA and protein expression levels of ITGB2 in HG-treated HK-2 cells were remarkably elevated. …”
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  5. 5725

    Distribution Characteristics and Coupling Relationship Between Soil Erosion and Hydrologic and Sediment Connectivity in Changchong River Basin by LI Jianing, ZHANG Hongli, TIAN Changyuan, ZHANG Yi, ZHA Tonggang

    Published 2024-12-01
    “…Among the hydrological and sediment connectivity grades, the proportion of 5° ~ 10° and 10° ~ 15° slope, 90.30 ~ 131.96 and 131.96 ~ 175.34 m elevation area is higher. The higher the grade, the higher the proportion of sunny slope area is. (4) Soil erosion has a significant positive correlation with hydrologic and sediment connectivity, mainly reflected in slope, slope direction, land use and elevation. …”
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  6. 5726

    Usp11 maintained the survival of marginal zone B cells under ionizing radiation by deubiquitinating DLL1 and JAG2 by Jiaqi Sheng, Depei Wu, Jingzhe Shang, Xiaodan Fu, He Gao, Jianjie Rong, Jun Wang, Jiancheng Hu, Xiaofei Qi

    Published 2025-02-01
    “…Conducted Co-IP and ubiquitination experiments for mechanism elucidation. Quantified IgM and IgG using ELISA and FC. Explored public databases for potential correlation molecules. …”
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  7. 5727

    Preparation of Sea-buckthorn Oil Microcapsule Composite Film and the Preservation Effect of Hand-grabbed Mutton by Bingbing ZHANG, Guishan LIU, Delang XIE, Haiyang MA, Yang LI, Fang MA, Xiaojun LI, Qingqing CAO, Xiaoxue LI, Qian ZHANG

    Published 2025-02-01
    “…Results showed that the embedding rate and yield of sea buckthorns oil microcapsules were 88.94% and 76.28%, respectively, and the optimum conditions for preparing the membrane were 6 g/100 mL gelatin concentration. The ratio of gelatin to glycerin was 1:0.4 and the drying conditions were 20 ℃ for 48 h. …”
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  8. 5728

    Co-administration of Hibiscus sabdariffa linn and Daflon-500® mitigates weight loss, hyperglycemia, hematological and oxidative changes in male rats with type-2 diabetes by Aishat Omobolanle Olatunji, Root Oluwapelumi Alegbe, Suleiman Folorunsho Ambali, Muftau Shittu, Ganiu Jimoh Akorede, Abdulfatai Aremu, Afisu Basiru, Jamila Abdulhamid Atata, Kolawole Yusuf Suleiman, Charles Amoto Shuaibu

    Published 2025-02-01
    “…Group 1(DW) received distilled water (2mL/kg) only. Group 2 (STZ; untreated), group 3 {MET; metformin (Glucophage)}, group 4 {HS; Hibiscus sabdariffa (400mg/kg)}, group 5 {DAF; daflon-500® (1000mg/kg)}, group 6 {DAF+HS; daflon-500® (1000mg/kg) and Hibiscus sabdariffa (400mg/kg)}, group 7 {DAF+MET+HS; daflon-500® (1000mg/kg), metformin (Glucophage), and Hibiscus sabdariffa (400mg/kg)}. …”
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  9. 5729
  10. 5730

    NAD<sup>+</sup>激活SIRT3/IDH2信号通路改善高血压血管内皮功能障碍 by 丘雨旻, 陈曦, 张建宁, 刘张弛, 朱秋霞, 张美信, 陶军, 吴杏

    Published 2025-01-01
    “…采用迁移实验和划痕实验评估体外内皮细胞功能;采用免疫荧光染色法检测mtROS水平;采用RT-PCR检测mtDNA、SIRT3、异柠檬酸脱氢酶2(IDH2)的mRNA表达;采用酶联免疫吸附法检测8-羟基-2'-脱氧鸟苷的水平;采用Western blot法检测p-eNOS、eNOS、SIRT3、IDH2蛋白表达水平。…”
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  11. 5731
  12. 5732
  13. 5733

    Influence of Secondary Inorganic Aerosol on the Concentrations of PM2.5 and PM0.1 during Air Pollution Episodes in Hanoi, Vietnam by Nguyen-Quoc Dat, Bich-Thuy Ly, Trung-Dung Nghiem, Thu-Thi Hien Nguyen, Kazuhiko Sekiguchi, Truong-Thi Huyen, Thai-Ha Vinh, Le-Quang Tien

    Published 2024-02-01
    “…In this study, the periods when daily PM2.5 concentrations exceeded the NAAQS of 50 µg m−3 for a minimum of two consecutive days were determined as episode periods. …”
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  14. 5734

    Association of blood manganese and selenium levels with hepatic steatosis among adolescents: a nationwide cross-sectional analysis by Bin You, Bin You, Bin You, Bin You, Zhiyuan Chen, Zhiyuan Chen, Zhiyuan Chen, Zhiyuan Chen

    Published 2025-02-01
    “…Hepatic steatosis was defined as a controlled attenuation parameter (CAP) score of ≥248 dB/m, a measure of liver steatosis, which is a primary characteristic and a less severe stage of hepatic steatosis, assessed by vibration-controlled transient elastography (VCTE). …”
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  15. 5735

    Transcriptome Analysis of Effect of Cordyceps militaris Aqueous Extract in Human Gastric Cancer Cell BGC-823 on Different RCD Pathways by Mingqi CUI, Kaiwen YU, Yang SONG, Fangxu XU, Shenghou WANG, Ze WANG

    Published 2025-02-01
    “…Cytological examination revealed typical apoptotic morphological characteristics in gastric cancer cells treated with the XG water extract, with an early apoptotic rate reaching 24.8%, while cell cycle arrest occurred at the G2/M stage. qRT-PCR showed that the expression of BCL2, BCL2L1, CASP3, CASP9, and XIAP was significantly inhibited (P<0.01), whereas that of ENDOG and AIF was significantly upregulated (P<0.01), consistent with the results of transcriptome sequencing. …”
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  16. 5736

    Bacteraemia in a Nigerian hospital: Implementing antimicrobial resistance surveillance by Adewale A. Amupitan, Adeyemi T. Adeyemo, Adefunke O. Amupitan, Temitope O. Obadare, Aaron O. Aboderin

    Published 2025-02-01
    “…Sixteen (30.2%) of 53 Gram-negative isolates were extended-spectrum beta-lactamase producers, predominantly harbouring blaCTX-M, three (5.7%) were AmpC beta-lactamase producers, and 20 (37.7%) were carbapenem-resistant, predominantly harbouring blaKPC. …”
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  17. 5737

    Prevalence of Hyper virulence and Multidrug resistance Klebsiella pneumoniae isolates from UTI patients by Manar Abdul karim, Zainab Mohammed Alzubaidy, Khazal Dabua Wadi

    Published 2025-01-01
    “…Serial dilutions were generated, and the resulting MIC values were found to be 512 and 1024µg/mL, respectively. The production of extended-spectrum beta-lactamases (ESBLs) was assessed through the utilisation of the double disc synergy test. …”
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  18. 5738
  19. 5739

    PTEN suppresses renal cell carcinoma proliferation and migration via inhibition of the PI3K/AKT pathway by Xu Xu, Yuan-Yue Tang, Xiaohong Liang, Wen Luo, Dong-Mei Jiang, Jie Chen

    Published 2025-02-01
    “…Results RT-qPCR results showed that PTEN expression was significantly increased in RCC tumor tissues compared to normal tissues (p < 0.01). However, PTEN mRNA levels were significantly reduced in 786-O cells compared to HK-2 cells (p < 0.01). …”
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  20. 5740

    Effect of Transcranial Direct-Current Stimulation and Task-Oriented Training on Electroencephalography-Based Motor Recovery Chronic Stroke: A Randomized Clinical Trial by Maryam Zolghadr, Shohreh Noorizadeh Dehkordi, Javad Sarrafzadeh, Saeed Talebian, Hassan Haddadzade Niri, Marzieh Yassin

    Published 2024-09-01
    “…Materials and Methods: Thirty chronic hemiparetic stroke survivors were randomly assigned to receive real or sham stimulation targeting the primary motor cortex (C3/C4) at 2 mA for 20 minutes and TOT daily over 15 sessions. …”
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