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5721
Bioinformatics insights into mitochondrial and immune gene regulation in Alzheimer's disease
Published 2025-02-01“…Moreover, qRT-PCR validation confirmed that the mRNA expression of the five biomarkers was consistent with bioinformatics results. …”
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5722
Saussurea gossypiphora extracts reduce inflammation by reversing inflammatory cytokine levels in in-vitro and in-vivo
Published 2025-02-01“…Results: The analysis of GC–MS of MESGD revealed the presence of various bio-active components such as Spirohexane-1-Carboxylic acid, ethyl ester; 1-Methyl-1-n-decycloxy-1-silacyclobutane; 1, 2, 4-Trioxolane-2-octanoic acid, 5-octyl, methyl ester; DPPH assay showed inhibition of free radicals by 40 - 95.66 % in the range of 25 – 1000 µg/mL concentrations, comparable with Ascorbic acid. …”
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5723
The effect of depth data and upper limb impairment on lightweight monocular RGB human pose estimation models
Published 2025-02-01“…The models were trained, validated and tested using the CMU Panoptic and Human3.6 M data sets as well as a custom data set. The custom data set includes RGB-D and optical motion capture data of 15 uninjured and 12 post-stroke individuals, while they performed movements involving their upper limbs. …”
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5724
Inhibition of complement system-related gene ITGB2 attenuates epithelial–mesenchymal transition and inflammation in diabetic nephropathy
Published 2025-02-01“…Also, VWF and ITGB2 were significantly related to the clinical features, including age, serum creatinine level, and GFR (MDRD). Besides, mRNA and protein expression levels of ITGB2 in HG-treated HK-2 cells were remarkably elevated. …”
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5725
Distribution Characteristics and Coupling Relationship Between Soil Erosion and Hydrologic and Sediment Connectivity in Changchong River Basin
Published 2024-12-01“…Among the hydrological and sediment connectivity grades, the proportion of 5° ~ 10° and 10° ~ 15° slope, 90.30 ~ 131.96 and 131.96 ~ 175.34 m elevation area is higher. The higher the grade, the higher the proportion of sunny slope area is. (4) Soil erosion has a significant positive correlation with hydrologic and sediment connectivity, mainly reflected in slope, slope direction, land use and elevation. …”
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5726
Usp11 maintained the survival of marginal zone B cells under ionizing radiation by deubiquitinating DLL1 and JAG2
Published 2025-02-01“…Conducted Co-IP and ubiquitination experiments for mechanism elucidation. Quantified IgM and IgG using ELISA and FC. Explored public databases for potential correlation molecules. …”
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5727
Preparation of Sea-buckthorn Oil Microcapsule Composite Film and the Preservation Effect of Hand-grabbed Mutton
Published 2025-02-01“…Results showed that the embedding rate and yield of sea buckthorns oil microcapsules were 88.94% and 76.28%, respectively, and the optimum conditions for preparing the membrane were 6 g/100 mL gelatin concentration. The ratio of gelatin to glycerin was 1:0.4 and the drying conditions were 20 ℃ for 48 h. …”
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5728
Co-administration of Hibiscus sabdariffa linn and Daflon-500® mitigates weight loss, hyperglycemia, hematological and oxidative changes in male rats with type-2 diabetes
Published 2025-02-01“…Group 1(DW) received distilled water (2mL/kg) only. Group 2 (STZ; untreated), group 3 {MET; metformin (Glucophage)}, group 4 {HS; Hibiscus sabdariffa (400mg/kg)}, group 5 {DAF; daflon-500® (1000mg/kg)}, group 6 {DAF+HS; daflon-500® (1000mg/kg) and Hibiscus sabdariffa (400mg/kg)}, group 7 {DAF+MET+HS; daflon-500® (1000mg/kg), metformin (Glucophage), and Hibiscus sabdariffa (400mg/kg)}. …”
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5729
Navigating the future of agri-food supply chain: A conceptual framework using bibliometric review
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5730
NAD<sup>+</sup>激活SIRT3/IDH2信号通路改善高血压血管内皮功能障碍
Published 2025-01-01“…采用迁移实验和划痕实验评估体外内皮细胞功能;采用免疫荧光染色法检测mtROS水平;采用RT-PCR检测mtDNA、SIRT3、异柠檬酸脱氢酶2(IDH2)的mRNA表达;采用酶联免疫吸附法检测8-羟基-2'-脱氧鸟苷的水平;采用Western blot法检测p-eNOS、eNOS、SIRT3、IDH2蛋白表达水平。…”
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5731
Reliea® combination of Codonopsis lanceolata and Chaenomeles sinensis extract alleviates airway inflammation on particulate matter 10 plus diesel exhaust particles (PM10D) ‑induced...
Published 2025-01-01“…Particulate matter (PM, diameter < 10 μm) and Diesel exhaust particles (DEP) exposure can cause severe respiratory disorders. …”
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5732
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5733
Influence of Secondary Inorganic Aerosol on the Concentrations of PM2.5 and PM0.1 during Air Pollution Episodes in Hanoi, Vietnam
Published 2024-02-01“…In this study, the periods when daily PM2.5 concentrations exceeded the NAAQS of 50 µg m−3 for a minimum of two consecutive days were determined as episode periods. …”
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5734
Association of blood manganese and selenium levels with hepatic steatosis among adolescents: a nationwide cross-sectional analysis
Published 2025-02-01“…Hepatic steatosis was defined as a controlled attenuation parameter (CAP) score of ≥248 dB/m, a measure of liver steatosis, which is a primary characteristic and a less severe stage of hepatic steatosis, assessed by vibration-controlled transient elastography (VCTE). …”
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5735
Transcriptome Analysis of Effect of Cordyceps militaris Aqueous Extract in Human Gastric Cancer Cell BGC-823 on Different RCD Pathways
Published 2025-02-01“…Cytological examination revealed typical apoptotic morphological characteristics in gastric cancer cells treated with the XG water extract, with an early apoptotic rate reaching 24.8%, while cell cycle arrest occurred at the G2/M stage. qRT-PCR showed that the expression of BCL2, BCL2L1, CASP3, CASP9, and XIAP was significantly inhibited (P<0.01), whereas that of ENDOG and AIF was significantly upregulated (P<0.01), consistent with the results of transcriptome sequencing. …”
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5736
Bacteraemia in a Nigerian hospital: Implementing antimicrobial resistance surveillance
Published 2025-02-01“…Sixteen (30.2%) of 53 Gram-negative isolates were extended-spectrum beta-lactamase producers, predominantly harbouring blaCTX-M, three (5.7%) were AmpC beta-lactamase producers, and 20 (37.7%) were carbapenem-resistant, predominantly harbouring blaKPC. …”
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5737
Prevalence of Hyper virulence and Multidrug resistance Klebsiella pneumoniae isolates from UTI patients
Published 2025-01-01“…Serial dilutions were generated, and the resulting MIC values were found to be 512 and 1024µg/mL, respectively. The production of extended-spectrum beta-lactamases (ESBLs) was assessed through the utilisation of the double disc synergy test. …”
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5738
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5739
PTEN suppresses renal cell carcinoma proliferation and migration via inhibition of the PI3K/AKT pathway
Published 2025-02-01“…Results RT-qPCR results showed that PTEN expression was significantly increased in RCC tumor tissues compared to normal tissues (p < 0.01). However, PTEN mRNA levels were significantly reduced in 786-O cells compared to HK-2 cells (p < 0.01). …”
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5740
Effect of Transcranial Direct-Current Stimulation and Task-Oriented Training on Electroencephalography-Based Motor Recovery Chronic Stroke: A Randomized Clinical Trial
Published 2024-09-01“…Materials and Methods: Thirty chronic hemiparetic stroke survivors were randomly assigned to receive real or sham stimulation targeting the primary motor cortex (C3/C4) at 2 mA for 20 minutes and TOT daily over 15 sessions. …”
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