Extraction of Saponins from Xanthoceras sorbifolium Bunge Leaves Using Deep Eutectic Solvents and Their Inhibitory Activity against Postharvest Pathogenic Fungi by Xue LI, Xinyu CHU, Erzheng SU, Jiahong WANG

“…Results showed that under the conditions of DES concentration of 47.00%, liquid-solid ratio of 42.00 mL/g, and extraction temperature of 43.00 ℃, the yield of XLs saponin using DES reached 10.22%±0.28%, representing a 38.8% increase compared to traditional solvents. …”
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Synthesis, evaluation of the biological activity against Trypanosoma cruzi and Leishmania donovani. Preliminary in silico ADMET studies of 5-nitroimidazole derivatives by Miguel A. Rodríguez, Ali Mijoba, Nereida J. Parra-Giménez, Zuleyma Blanco, Katiuska Chávez, Alirica I. Suárez, Esteban Fernandez-Moreira, Hegira Ramírez, Jaime E. Charris

“…Sulfonyl derivative 8b was the most promising compound with IC50: 9.58 ± 2.02 μM and with a selectivity index (SI) greater than 31.31, that justifies the description as a promising hit for further study as a possible antichagasic agent.…”
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Feasibility of transpedicular screw placement through the posterior arch of C1: A CT study in the Emirati population by Ivan James Prithishkumar, Dineshwary Suresh, Nerissa Naidoo, Rashid AlSharhan, Usama Al Bastaki, Jeyaseelan Lakshmanan, Baylis Vivek Joseph

“…Methods: Computed tomography images of the cervical spine in 160 adults (>18 years) who are natives of the United Arab Emirates (UAE) (M = 80; F = 80) were reviewed. Morphometric parameters relevant to pedicle screw fixation via the posterior arch were studied. …”
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Disorders of esophageal clearance in gastroesophageal reflux disease and option of their treatment by O. A. Storonova, A. S. Trukhmanov, N. L. Dzhahaya, V. T. Ivashkin

“…The body mass index in group was elevated (mean —25,0 [24,2; 28,6] kg/m2). Patients underwent esophagogastroduodenoscopy (EGDS), 24-hour pH-metry, X-ray investigation with barium meal, investigation of esophageal motor function. …”
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Differences in Physical and Psychological Parameters in Sub-Elite, Male, Youth Soccer Players with Jumper's Knee Following Physical Therapy Compared to Healthy Controls: A Longitud... by Marc Niering, Thomas Muehlbauer

“…Outcome measures included muscle power (drop jump, jump-and-reach), change of direction speed \[CODS\] (acyclic sprint), speed (tapping, 30-m linear sprint), endurance (Yo-Yo intermittent recovery test level 1), the Achievement Motives Scale (AMS) Sport, and injury-/pain-related data. …”
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Advanced analysis of soil pollution in southwestern Ghana using Variational Autoencoders (VAE) and positive matrix factorization (PMF) by Raymond Webrah Kazapoe, Daniel Kwayisi, Seidu Alidu, Samuel Dzidefo Sagoe, Aliyu Ohiani Umaru, Ebenezer Ebo Yahans Amuah, Millicent Obeng Addai, Obed Fiifi Fynn

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The Single Leg Squat Test: A “Top-Down” or “Bottom-Up” Functional Performance Test? by Lindsay A Carroll, Benjamin R Kivlan, RobRoy L Martin, Amy L Phelps, Christopher R Carcia

“… # Methods Sixty-five healthy, active volunteers (sex = 50 female, 15 male; age = 25.2 +/- 5.6 years; height = 1.7 +/- .1 m; weight = 68.5 +/- 13.5 kg) who demonstrated static balance and hip abductor strength sufficient for performance of the SLST participated in the study. …”
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Overview of Aerosol and Air Pollution in South Eastern Asia Countries by Tsrong-Yi Wen, Somporn Chantara, Juliana Jalaludin, Puji Lestari, Arie Dipareza Syafei, Pham Van Toan, Ying I. Tsai

“…In Chiang Mai, the highest PM mass and PAHs concentrations were found in the finest particle sizes (0.65 µm–0.43 µm) in periods of intensive open burning (IOB) and low open burning (LOB), in both urban and rural areas, and the PAHs concentration (5.10 ng m−3) in the fine fraction accounted for 45% to 47% and 32% to 37% during IOB and LOB periods, respectively. …”
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Annual Variation of PM2.5 Chemical Composition in Ho Chi Minh City, Vietnam Including the COVID-19 Outbreak Period by Ngoc Tran, Yusuke Fujii, Vinh Xuan Le, Nguyen Doan Thien Chi, Hiroshi Okochi, To Thi Hien, Norimichi Takenaka

“…The PM2.5 mass concentration during the sampling period was 28.44 ± 11.55 µg m−3 (average ± standard deviation). OC, EC, and total WSIs accounted for 30.7 ± 6.6%, 9.7 ± 2.9%, and 24.9 ± 6.6% of the PM2.5 mass, respectively. …”
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Vitamin D Deficiency in Patients with Type 2 Diabetes Mellitus with and without Pulmonary Tuberculosis by Wahiduddin Wahiduddin, Agung Pranoto, Sudjarwo Sudjarwo

“…Vitamin D deficiency was not associated with the incidence of pulmonary TB in T2DM, whereas female sex, age> 50 years, BMI ? 25.0 kg /m2, and duration of T2DM> 5 years were associated with vitamin D deficiency (p <0.05). …”
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Diverse biological roles of PhoP/PhoQ in Pseudomonas plecoglossicida: Impact on stress responses and virulence by Meiqin Mao, Li He, Xiangyang Lin, Jianshao Wu, Pan Wang, Chuanzhong Zhu, Qingpi Yan

“…In artificial infection experiments, the ΔphoQ strain showed significantly reduced virulence when infecting hybrid grouper (Epinephelus fuscoguttatus♀ × E. lanceolatus♂), with an LD50 value of 3.931 × 104 cfu/mL. These results suggest that the PhoP/PhoQ system may play a key role in regulating the environmental adaptability and pathogenicity of P. plecoglossicida.…”
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FreshWater Watch: Investigating the Health of Freshwater Ecosystems, from the Bottom Up by Isabel Bishop, Amedeo Boldrini, Wim Clymans, Charlotte Hall, Heather Moorhouse, Stephen Parkinson, Kesella Scott-Somme, Ian Thornhill, Steven Loiselle

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Ex vivo delivery of recombinant IL-10 to human donor lungs by Jonathan C. Yeung, Terumoto Koike, Dirk Wagnetz, Tiago N. Machuca, Riccardo Bonato, Mingyao Liu, Stephen Juvet, Marcelo Cypel, Shaf Keshavjee

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Aprendizaje a través de estrategias lúdicas: una herramienta para la Educación Ambiental by Reichel Rodríguez-Miranda, Luis Palomo-Cordero, Michael Padilla-Mora, Andrea Corrales-Vargas, Berna van Wendel de Joode

“…[Resultados]: Un 38 % (n=14) de escuelas estaban ubicadas a <100 m de fincas bananeras. En los talleres, la comunicación basada en el uso de diversas estrategias pedagógicas lúdicas generó un ambiente participativo, que identificó necesidades locales, construcción de saberes colectivos y conocimiento sobre efectos de la exposición a plaguicidas en salud humana y ambiental. …”
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Elevated POSTN expression predicts poor prognosis and is associated with radioresistance in cervical cancer patients treated with radical radiotherapy by Cui-qin Huang, Wen-tao Xiao, Xiang-rong Yao, Zhi-min Li, Jun-yan He

“…We analyzed data from 92 CC patients in The Cancer Genome Atlas (TCGA) and 153 patients from our institution, assessing POSTN expression levels through mRNA analysis and immunohistochemistry (IHC). Our findings revealed that high POSTN expression was significantly associated with advanced tumor stages, poorer radiotherapy outcomes, and worse overall survival (OS). …”
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Short-term outcomes of oropharyngeal administration of colostrum in preterm neonates: a double-blind placebocontrolled randomized trial by Ameneh Lamsehchi, Maryam Shokouhi Solgi, Mohammad Kazem Sabzehei, Behnaz Basiri, Elahe Talebi Ghane, Kiana Kimiaei Asadi, Sina Azadnajafabad

“…The intervention and control arms received 0.2 mL of their mother’s colostrum or distilled water via oropharyngeal administration every 6 hours for 3 days starting from birth until 72 hours of age. …”
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Immunogenicity of Two Fractional Inactivated Poliovirus Vaccine Doses vs Single Intramuscular Inactivated Poliovirus Vaccine Dose in Infants of Low- and Middle-income Countries: A... by Kunal Kumar, Sangita Yadav, Raghvendra Singh, Archana Thakur

“…Results: Pre- and postimmunization mean antibody titers (MAT) in pg/mL against types I, II, and III PVs in the ID group were 192.26 ± 49.5, 162.96 ± 34.1, 131.32 ± 38.4, and 1743.58 ± 391.6, 1272.10 ± 341.3, 1105.71 ± 331.1, respectively. …”
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Health Risk Assessment of PM2.5-bound Components in Beijing, China during 2013–2015 by Tianchu Zhang, Yangfan Chen, Xiaohong Xu

“…The three-year average PM2.5 mass concentration was 82 µg m–3. Both lifetime cancer risk (1.9E-4) from exposure to ambient PM2.5-bound elements and PAHs and non-cancer HQ (18) from exposure to ambient PM2.5-bound elements in Beijing were much higher than the corresponding U.S. …”
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The drivers of mental health service utilisation among public primary healthcare workers in Negeri Sembilan. by Norhafizah Mohd Noor, Ahmad Azuhairi Ariffin, Halimatus Sakdiah Minhat, Lim Poh Ying, Umi Adzlin Silim

“…Significant drivers predicting MHSU were B40 household income (aOR = 3.426, 95% CI: 1.588, 7.393, p-value = 0.002) and M40 household income (aOR = 3.781, 95% CI: 1.916, 7.460, p-value<0.001), low supervisor support (aOR = 2.302, 95% CI: 1.206, 4.392, p-value = 0.011), received mental health training (aOR = 2.058, 95% CI: 1.221, 3.469, p-value = 0.007) and high co-worker support (aOR = 1.701, 95% CI: 1.034, 2.798, p-value = 0.036).…”
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Guar gum-modified magnetic palladium nanocatalyst: C–N coupling reaction and STAT3-Mediated breast cancer therapy by Junrui Luan, Xin Dong, Shuwen Zhou

“…The Fe3O4@guar gum/Pd NPs showed an IC50 value of 62 μg/mL against MCF-10, respectively. The presence of the material resulted in a 40–50% induction of cell apoptosis, along with down regulation of the anti-apoptotic marker. …”
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