Aldehyde Dehydrogenase 2 rs671 Polymorphism is Associated with Susceptibility of Coronary Atherosclerosis in Patients with Hypertension by Hou H, Huang S, Huang W, Huang L, Zhang Z, Liang L

“…Logistic analysis showed that body mass index (BMI) ≥ 24.0 kg/m2 (odds ratio (OR): 1.670, 95% confidence interval (CI): 1.185– 2.352, p=0.003), history of smoking (OR: 2.024, 95% CI: 1.263– 3.243, p=0.003), ALDH2 rs671 G/A genotype (OR: 1.821, 95% CI: 1.280– 2.589, p=0.001), high TC (OR: 1.592, 95% CI: 1.021– 2.485, p=0.040), high SII (OR: 2.290, 95% CI: 1.386– 3.784, p=0.001), and high SIRI (OR: 1.727, 95% CI: 1.126– 2.650, p=0.012) were associated with coronary atherosclerosis in patients with hypertension.Conclusion: Overweight (BMI ≥ 24.0 kg/m2), history of smoking, ALDH2 rs671 G/A genotype, high TC, SII, and SIRI levels were associated risk factors for coronary atherosclerosis in patients with hypertension.Keywords: coronary atherosclerosis, hypertension, ALDH2, systemic immune inflammation index, system inflammation response index…”
Get full text

Hematobiochemical changes of lead Poisoning and amelioration with Coconut (<i>Cocos nucifera</i> L.) Water in wistar albino rats by Enagbonma Ben Jesuorsemwen, Iyorah Imeda Ebikere, Iyorah Imeda Ebikere, Igiehon Nicholas Ozede, Aimuanmwosa Frank Eghomwanre

“…The mean values of red  blood  cells, mean corpuscular volume, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, red blood cell distribution width and platelets  (8.10±0.63(×106μl), 52.7±0.87(μm3), 17.9±0.56(pg), 34.73±0.65(g/dl), 17.90±0.67(%) and 670.00±42.22(×103μl) respectively) reduced in lead treated rats when compared with control mean values (8.41 ± 0.90(×106μl), 56.60 ± 1.55(μm3), 19.33 ± 0.82(pg), 34.93 ± 0.90(g/dl), 18.27 ± 0.73(%) and  818.33± 123.68(×103μl) respectively ) and these values increased in75ml coconut water only group and the group of 0.10g/l lead + 75ml coconut water  except mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, and red blood cell distribution width of the 75ml coconut water only. …”
Get full text

Systemic delivery of AAV5, AAV8, and AAV9 packaging a C5-12-microdystrophin-FLAG expression cassette in non-human primates by Mengping Liu, Erica Cook, Yanshan Dai, Erich Ehlert, Francois du Plessis, Jacek Lubelski, Bogdan G. Sleczka, Petia Shipkova, Zhuyin Li, Joshua Gamse, David Gordon, Leonard P. Adam, Paul C. Levesque, Glen B. Banks

“…AAV8 led to higher levels of microdystrophin-FLAG mRNA and protein in the cardiac ventricles and skeletal muscles when compared to AAV5 or AAV9. …”
Get full text

Effectiveness and safety of metformin in 51 675 patients with type 2 diabetes and different levels of renal function: a cohort study from the Swedish National Diabetes Register by Katarina Eeg-Olofsson, Soffia Gudbjörnsdottir, Ann-Marie Svensson, Björn Eliasson, Linus Schioler, Björn Zethelius, Nils Ekström, Jan Cederholm, Junmei Miao Jonasson

“…Metformin, compared with any other treatment, showed reduced risks of acidosis/serious infection (adjusted HR 0.85, 95% CI 0.74 to 0.97) and all-cause mortality (HR 0.87, 95% CI 0.77 to 0.99), in patients with eGFR 45–60 ml/min/1.73 m2, and no increased risks of all-cause mortality, acidosis/serious infection or CVD were found in patients with eGFR 30–45 ml/min/1.73 m2.Conclusions Metformin showed lower risk than insulin for CVD and all-cause mortality and slightly lower risk for all-cause mortality compared with other OHA, in these 51 675 patients followed for 4 years. …”
Get full text

Effect of different diets on the fatty acid composition of buffalo bulk milk by Sebastiana Failla, Giuliano Palocci, Michela Contò, Gianluca Renzi, Chiara Evangelista, Loredana Basiricò, Umberto Bernabucci

“…While milk from the CG and TG diets showed an increase (p<0.001) in PUFA n-6, the differences were also evident in the n6/ n3 ratio (3.1 vs. 5.2, p<0.001). Diets with T and M showed an increase (p<0.002) in SFA and a decrease (p<0.001)  in CLA (-20%). …”
Get full text

Different lysine-to-methionine ratios in a low-protein diet affect the microbiome and metabolome, influencing the jejunal barrier function in Tibetan sheep by Fengshuo Zhang, Zhenling Wu, Yu Zhang, Quyangangmao Su, Kaina Zhu, Xuan Chen, Shengzhen Hou, Linsheng Gui

“…These groups were supplemented with different Lys/Met ratios of 3 [low protein-high methionine (LP-H)], 2 [low protein-medium methionine (LP-M)], and 1 [low protein-low methionine (LP-L)] in the basal diet (10% crude protein). …”
Get full text

The change rule of smoke dispersion and temperature evolution in fires within lithium iron phosphate energy storage prefabricated cabin by ZHANG Yin, QIN Chaoqun, TIAN Shuangshuang, GE Zhichao, DONG Jun, ZHANG Xiaoxing

“…This perfluorohexane fire extinguishing system, with a sprinkler intensity of 20 L/(min ·m2), a sprinkler angle of 120°and a particle size of 50 μm, can successfully controls fires and mitigates fire damage. …”
Get full text

Exploring DNA methylation, telomere length, mitochondrial DNA, and immune function in patients with Long-COVID by Andrea Polli, Lode Godderis, Dries S. Martens, Madhura Shekhar Patil, Jolien Hendrix, Arne Wyns, Jente Van Campenhout, Emma Richter, Lara Fanning, Olivia Vandekerckhove, Eveline Claeys, Wim Janssens, Natalie Lorent

Get full text

Baryon Pasting the Uchuu Light-cone Simulation by Erwin T. Lau, Daisuke Nagai, Arya Farahi, Tomoaki Ishiyama, Hironao Miyatake, Ken Osato, Masato Shirasaki

“…These BP-Uchuu maps are constructed using more than 75 million dark matter halos with masses M _500 _c ≥ 10 ^13 M _⊙ within the redshift range 0 ≤ z ≤ 2. …”
Get full text

Mechanism of Photocatalytic Degradation of Diclofenac in Water by a Novel Carbon Nitride by LIU Zi’ang, GAO Yifang, LIU Chao, LI Wenjun, LIU Xiaona, LI Bo, QIAN Tianwei

“…[Findings] The results show that the specific surface area of PCN (133.963 m2/g) is significantly higher than that of GCN (2.605 m2/g), about 67 times that of GCN. …”
Get full text

Improving Fugitive Dust Emission Inventory from Construction Sector Using UAV Images Recognition by Yuyao He, Jicheng Jang, Yun Zhu, Pen-Chi Chiang, Jia Xing, Shuxiao Wang, Bin Zhao, Shicheng Long, Yingzhi Yuan

“…Post integration of monitoring data through the Software for the Modeled Attainment Test - Community Edition (SMAT-CE), the contributions of construction dust to local PM10 and PM2.5 concentrations were estimated at 3.27 ± 0.8 µg m–3 and 1.11 ± 0.27 µg m–3, respectively, with more pronounced impacts observed in the central, northwestern, and south-central zones of the study region. …”
Get full text

Pollution Characteristics and Source Analysis of Carbonaceous Components in PM2.5 in a Typical Industrial City by Liyan Ma, Dongmei Hu, Yulong Yan, Yueyuan Niu, Xiaolin Duan, Yafei Guo, Wanhua Li, Lin Peng

“…The OC and EC concentrations and annual average ratio of OC/EC in Jincheng were 5.54 µg m−3, 0.98 µg m−3, and 5.67, respectively. The concentration change in carbonaceous components shows strong seasonality and daily variation characteristics, and the influence of biomass combustion on carbonaceous components in winter cannot be ignored. …”
Get full text

Lactobacillus fermentum B153 from human colostrum modulates intestinal immunity and gut microbiota in obese mice model by Juqing Huang, Xiaohui Cai, Xiaoyan Liu, Gongti Lai, Xuefang Guan, Bingyan Chen, Qi Wang

“…Intestinal inflammation induced by the high-fat diet was alleviated by L. fermentum B153, as evidenced by the upregulation of E-cadherin and IL-6 mRNA expression, alongside the downregulation of TNF-α mRNA expression. …”
Get full text

Modelling and Analysis of Bioretention Systems for Removal of Stormwater Pollutants by Nuwagaba, Emmanuel, Abdulkadir, Taofeeq Sholagberu, Agwe, Michael Tobby, Philip, Tibenderana, Ako, Terseer, Moses N., Twesigye-omwe

“…Each of the Columns has four layers arranged as follows: Column B (Layer 1 for fine sand of 0.063 – 1.18 mm; Layer 2 for Coarse Sand of 1.18-4.75; Layer 3 for fine aggregate AASHTO M43, 4.75-9.5mm; and Layer 4 for Coarse aggregate >9.5mm), and Column C (Layer 1 for black soil with mulch and plants; fine Sand of 1.18-0.063; Layer 3 for fine aggregate AASHTO M43, 4.75-9.5mm; and Layer 4 for Coarse aggregate >9.5mm). …”
Get full text

Citrus Diseases Exotic to Florida: Citrus Leprosis by Ozgur Batuman, Amit Levy, Ajia Paolillo, Kuang-Ren Chung, Ron Brlansky

“…Batuman, A. Levy, P. Sieburth, A. M. Paolillo, K.-R. Chung, and R. H. Brlansky, and published by the UF/IFAS Plant Pathology Department. https://edis.ifas.ufl.edu/pp148 Previous version: Chung, Kuang-Ren, and Ronald Brlansky. 2006. …”
Get full text

Kyoto International Consensus Report on Anatomy, Pathophysiology and Clinical Significance of the Gastroesophageal Junction by A. A. Sheptulin, Y. S. Rabotyagova

Get full text

Community-Based Home Energy Tune-Up/Audit Programs: A Step-by-Step Guide to Creating and Implementing Energy Equity Programs in Your Community by Alane Humrich, Lee Hayes Byron, Jennison Kipp, Marianne Schmink, Kimberly Davis, Paul Monaghan

Get full text

Socio-Demographic Characteristics and Concerns about Water Quality Issues of Master Gardener Program Volunteers by Tatiana Borisova, Michael Smolen, Maria Pilar Useche, Jon Calabria, Nickola Sochacka, Damian Adams, Diane Boellstorff, Jason Evans, Robert Mahler

Get full text