Increased distribution of carbon metabolic flux during de novo cytidine biosynthesis via attenuation of the acetic acid metabolism pathway in Escherichia coli by Tong Ye, Wei Ding, Zhengxu An, Haojie Zhang, Xiaobo Wei, Junnan Xu, Huiyan Liu, Haitian Fang

“…After 39 h of fermentation in 500 mL shake flasks, the cytidine yields of strains K12ΔpoxB and K12ΔpoxBΔpta were 1.91 ± 0.04 g/L and 18.28 ± 0.22 g/L, respectively. …”
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Efficient Feature Selection and Hyperparameter Tuning for Improved Speech Signal-Based Parkinson’s Disease Diagnosis via Machine Learning Techniques by Deepak Painuli, Suyash Bhardwaj, Utku Kose

“…To enhance model performance, the GridSearchCV method was employed for hyperparameter tuning, alongside recursive feature elimination (RFE) and minimum redundancy maximum relevance (mRMR) feature selection techniques. Among the 12 ML models evaluated, the RF model with the RFE-generated feature subset (RFE-50) emerged as the top performer. …”
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Utilizing the subtractive proteomics approach to design ensemble vaccine against Candida lusitaniae for immune response stimulation; a bioinformatics study. by Habiba Naz, Rimsha Timotheous, Muhammad Farhan Sarwar, Tariq Nadeem, Mudassar Fareed Awan, Sajed Ali, Sophia Awais, Irfan Ahmed

“…Upon final results, it was found that highest count of IgG and IgM was achieved i.e., up to 700000 between the days 8 to 13 and then slowly neutralized till the day 30. …”
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Effect of Pulmonary Rehabilitation on Dyspnoea, Functional Capacity and Thoracic Excursion in Chronic Obstructive Pulmonary Disease: A Case Report by Priyanka K Chilhate, Lajwanti Lalwani (Adwani)

“…Before starting treatment, a baseline assessment was done, including measures like Modified Medical Research Council (mMRC) grading for breathlessness, 6-Minute Walk Distance (6MWD) and chest movement. …”
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Relationship between RSV-hospitalized children and meteorological factors: a time series analysis from 2017 to 2023 by Shuying Wang, Yifan Wang, Yingxue Zou, Cheng-liang Yin

“…Meteorological data were collected from the Tianjin Binhai International Airport meteorological station, encompassing temperature (℃), air pressure (mmHg), wind speed (m/s), humidity (%), and precipitation (mm). We employed seasonal ARIMA and GAM models to investigate the association between meteorological factors and RSV-related hospitalizations. …”
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One-pot low-temperature preparation of thermo-responsive self-ceramifiable glass fiber insulation tiles with exceptional mechanical and ablative properties by Fengchun Ji, Zhihang Peng, Xin Yang, Jian Feng, Yang Xiang, Zeyu Liu

“…The study first introduces a novel thermo-responsive self-ceramifiable glass fiber rigid insulation tile (GFRIT) characterized by low forming temperature (150 °C), low density (0.435 g/cm3), high compressive strength (1.58 MPa), and low thermal conductivity (0.0553 W/(m·K)) in normal circumstances. Interestingly, it can spontaneously transform into high-strength semi-crystalline ceramics at elevated temperatures. …”
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The Role of PM2.5 Chemical Composition and Meteorology during High Pollution Periods at a Suburban Background Station in Southern Poland by Barbara Błaszczak, Natalia Zioła, Barbara Mathews, Krzysztof Klejnowski, Krzysztof Słaby

“…During the measurement period, PM2.5 concentrations exceeding 50 µg m–3 were recorded on 38 days, and 7 pollution episodes were detected. …”
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5-Fluorouracil-β-Cyclodextrin conjugates:Linker strategies to enhance the anticancer efficacy and reduce the side effects by Liangliang Hu, Ting Meng, Davies Marabada, Zhichao Jin, Qing Huang, Shijie Wei, Zhizhong Wang

“…The cytotoxicity assays on human colon cancer cell lines HT-29 and normal colon epithelial cells NCM-460 demonstrated that the IC50 value of the 5-FUBA-β-CD conjugate for the HT-29 cells was 38.72 ± 0.13 μM, indicating superior antitumor activity compared to both 5-FUBA-β-CD and 5-FU. …”
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Black Carbon Concentration and Potential Source Regions: A Case Study of the Yellow River Basin in Shandong Province, China by Yuxia Wang, Yanni Rong, Kai Qu, Qing Zhao, Yingming Jiang, Xiaolei Bao, Yang Wang

“…The monthly average BC concentrations in Jinan ranged from 0.69 to 3.92 µg m–3. BC concentration exhibited a pronounced diurnal variation, which decreased from the morning peak to afternoon. …”
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Iron(III) edta-accelerated growth of gold/silver core/shell nanoparticles for wide-range colorimetric detection of hydrogen peroxide by Mahdi Hemmati, Amir Hossein Q. Selakjan, Forough Ghasemi

“…Under well-optimized conditions, various concentrations of H2O2 ranging from 1.0 to 50 µΜ have shown an acceptable linear relationship with different colors and, with a limit of detection (LOD) of 230 nM. Furthermore, various real samples were examined to confirm the practicality of our developed probe.…”
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Promoted Catalytic Properties of Acetone over Cerium-Modified Mullite Catalyst YMn2O5 by Xiaotian Mu, Wenhuan Wang, Kai Zhang, Honglei Ding, Weiguo Pan

“…Experimental results confirm that Y0.9Ce0.1Mn2O5 had optimum acetone oxidation activity, completely achieving 100% acetone conversion at 120°C under the reaction conditions of acetone concentration = 1000 ppm, 20 vol% O2/N2 and WHSV = 36000 mL g−1 h−1. This excellent catalytic activity comes from its larger specific surface area and higher Mn4+/Mn3+ molar ratio. …”
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Long-term Air Pollution Exposure Impact on COVID-19 Morbidity in China by Yihan Wu, Qingming Zhan, Qunshan Zhao

“…Our statistical analysis indicates that a 1 µg m−3 increase of PM2.5, PM10, NO2 and O3 can result in 1.95% (95% CI: 0.83–3.08%), 0.55% (95% CI: −0.05–1.17%), 4.63% (95% CI: 3.07–6.22%) rise and 2.05% (95% CI: 0.51–3.59%) decrease of COVID-19 morbidity. …”
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Characteristics of Plasmodium vivax apicomplexan amino acid transporter 8 (PvApiAT8) in the cationic amino acid transport by Wang-Jong Lee, Ernest Mazigo, Jin-Hee Han, Seok Ho Cha

“…Kinetic analysis showed saturable uptake for L-arginine consistent with Michaelis-Menten kinetics, with a Km of 1.5 ± 0.3 µM and a Vmax of 25.0 ± 4.8 pmol/oocyte/hr. Inhibition assays further confirmed its selectivity for cationic amino acids such as L-arginine, L-lysine, L-histidine, and L-ornithine. …”
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Microscale insight into the proton concentration during electrolytic reaction via an optical microfiber: potential for microcurrent monitoring by a dielectric probe by Yunyun Huang, Jiaxuan Liang, Haotian Wu, Pengwei Chen, Aoxiang Xiao, Bai-Ou Guan

“…The sensing region is a microfiber with a diameter of 8.8 μm. It can get invaluable information that cannot be obtained through conventional electrochemical methods. …”
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Respirable Particles and Gas Contaminants Emissions from a Desktop Laser Cutter and Engraver by Kevin O’Neill, Xinyi Niu, Jun Wang, Runcheng Fang

“…Cardboard consistently exhibited the highest concentration of respirable particulate matter of 253.9 ± 47.6 mg m–3 and an average emission rate of sub-half-micron particles of 5.8 × 1010 # min–1, characterized by the smallest geometric mean diameter of 53 nm in the absence of ventilation. …”
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Clinical, immune and genetic risk factors of malaria-associated acute kidney injury in Zambian children: A study protocol. by Chisambo Mwaba, Sody Munsaka, David Mwakazanga, David Rutagwerae, Owen Ngalamika, Suzanna Mwanza, Mignon McCulloch, Evans Mpabalwani

“…In addition, we intend to assess a modified renal angina index (mRAI), kidney injury molecule-1 (KIM-1), neutrophil gelatinase-associated lipocalin (NGAL), and soluble urokinase receptor (suPAR), when done on the first day of admission, for the ability to predict AKI two days later (day 3) in children admitted with malaria.…”
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Biomonitoring potential of trace metal accumulation and bioavailability in coral skeletons and reef sediments of Persian Gulf: A comparative study by Seyed Hassan Mousavi, Mehdi Gholamalifard, Seyed Mahmoud Ghasempouri

“…Then freeze-dried sediments and coral powder were ground, sieved (63 μm), digested (using United States Environmental Protection Agency - Method 3050b) and filtered (Whatman No. 42). …”
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Evaluation and Management of Women who Have Experienced Stillbirth in Their Previous Pregnancies by Erdem Fadiloglu, Atakan Tanacan, Canan Unal, Mehmet Sinan Beksac

“…After detection of pregnancy, the patients were administered low-dose low-molecular-weight heparin (LMWH) (enoxaparin, 1×2000 Anti-XA IU/0.2 mL/day), low-dose salicylic acid (100 mg/day) and low-dose corticosteroid (methylprednisolone, 1×4 mg/day orally) in necessary cases. …”
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Integration of transcriptomics and metabolomics data revealed role of insulin resistant SNW1 gene in the pathophysiology of gestational diabetes by Ravi Bhushan, Rimjhim Trivedi, Ritu Raj, Anjali Rani, Sangeeta Rai, Anima Tripathi, Shiv Govind Rawat, Ajay Kumar, Dinesh Kumar, Pawan K. Dubey

“…Metabolomic studies indicated significantly elevated gluconeogenesis in GDM, evidenced by decreased levels of alanine and increased levels of pyruvate and glucose compared to controls. siRNA-mediated knockdown of SNW1 in PANC1 cells resulted in significant down-regulation of alanine aminotransferase (ALT/GPT) and insulin receptor substrate (IRS1), while glucose transporters (GLUT2/GLUT4) and insulin (INS) were significantly up-regulated at both mRNA and protein levels. This study identified SNW1 as a novel insulin-resistant gene that induces hyperglycemia by elevating gluconeogenesis and decreasing glucose uptake. …”
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Functional MRI-guided microsurgery of intracranial arteriovenous malformations: study protocol for a randomised controlled trial by Shuo Wang, Yuanli Zhao, Jun Wu, Bing Zhao, Yong Cao

“…Surgical complications and outcomes at pretreatment, post-treatment, at discharge and at 1-month, 3-month and 6-month follow-up intervals will be analysed using the modified Rankin Scale (mRS). This trial will determine whether fMRI-guided microsurgery could improve outcomes in patients with AVMs and also identify the safety and efficacy of fMRI-guided microsurgery.Ethics and dissemination The study protocol and written informed consent were reviewed and approved by the Institutional Review Board of Beijing Tiantan Hospital Affiliated to Capital Medical University (ky2012-016-02). …”
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