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Cortical Lewy Body Dementia
Published 1990-01-01“…In cortical Lewy body dementia the distribution of Lewy bodies in the nervous system follows that of Parkinson's disease, except for their greater profusion in the cerebral cortex. …”
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Cognitive profile in mild cognitive impairment with Lewy bodies
Published 2023-08-01Subjects: Get full text
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White matter hyperintensities and cholinergic degeneration as Lewy body disease
Published 2025-01-01“…Anterior periventricular WMHs may represent axonal alterations caused by the interplay between Lewy body‐related degeneration and vascular pathologies.…”
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Preclinical Polymodal Hallucinations for 13 Years before Dementia with Lewy Bodies
Published 2014-01-01“…We describe a case of dementia with Lewy bodies (DLB) that presented long-lasting preclinical complex polymodal hallucinations. …”
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REM Sleep Behavior Disorder (RBD) in Dementia with Lewy Bodies (DLB)
Published 2018-01-01“…RBD is either idiopathic or secondary to other neurologic disorders and medications. Dementia with Lewy bodies (DLB) is the third most common cause of dementia, and the typical clinical presentation is rapidly progressive cognitive impairment. …”
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Distinct subcellular localization of tau and alpha-synuclein in lewy body disease
Published 2025-01-01Subjects: Get full text
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Age-dependent alpha-synuclein aggregation and Lewy body formation in Parkinson’s disease
Published 2025-12-01Get full text
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Idiopathic REM Sleep Behavior Disorder: Implications for the Pathogenesis of Lewy Body Diseases
Published 2011-01-01“…Both results of the odor identification and cardiac 123I-metaiodobenzylguanidine accumulation have been investigated for their potential to enhance the detection of pathogenesis resembling that of Lewy body-related α-synucleinopathies in patients clinically diagnosed as having idiopathic REM sleep behavior disorder. …”
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An overview of methods for the treatment and diagnosis of dementia with Lewy bodies. Clinical case analysis
Published 2020-12-01Subjects: “…dementia with Lewy bodies…”
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Association of Alzheimer’s and Lewy body disease pathology with basal forebrain volume and cognitive impairment
Published 2025-01-01“…Abstract Background Degeneration of the basal forebrain cholinergic system is a hallmark feature shared by Alzheimer’s disease (AD) and Lewy body disease (LBD) whereas hippocampus atrophy is more specifically related to AD. …”
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Increased plasma DOPA decarboxylase levels in Lewy body disorders are driven by dopaminergic treatment
Published 2025-01-01“…Abstract DOPA Decarboxylase (DDC) has been proposed as a cerebrospinal fluid (CSF) biomarker with increased concentrations in Lewy body disorders (LBDs) and highest levels in patients receiving dopaminergic treatment. …”
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Glucose Metabolic Brain Network Differences between Chinese Patients with Lewy Body Dementia and Healthy Control
Published 2018-01-01“…Dementia with Lewy bodies (DLB) is the second most common degenerative dementia of the central nervous system. …”
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Metabolic Risk Factors of Alzheimer’s Disease, Dementia with Lewy Bodies, and Normal Elderly: A Population-Based Study
Published 2018-01-01“…Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB) share many risk factors. Evidence suggests that metabolic risk factors are important to AD; however, their association with DLB is unclear. …”
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Mini Review: Anticholinergic Activity as a Behavioral Pathology of Lewy Body Disease and Proposal of the Concept of “Anticholinergic Spectrum Disorders”
Published 2016-01-01“…Based on these hypotheses, we consider AA to be a behavioral pathology of Lewy body disease. We also propose the concept of “anticholinergic spectrum disorders,” which encompass a variety of conditions, including AD, Lewy body disease, and delirium. …”
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<i>Eugenia uniflora</i> Effects on the Depressive-like Behavior of MPTP-Exposed Female Rats: Apoptosis and α-Synuclein Modulation
Published 2025-01-01Subjects: Get full text
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Is Parkinson’s Disease Truly a Prion-Like Disorder? An Appraisal of Current Evidence
Published 2015-01-01“…Characterised by a loss of dopaminergic neurons and the development of intraneuronal inclusions known as Lewy bodies, it has classically been thought of as a cell-autonomous disease. …”
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Dementia in Parkinson's Disease Correlates with α-Synuclein Pathology but Not with Cortical Astrogliosis
Published 2012-01-01“…We did confirm the previously identified positive correlation between the presence of cortical Lewy bodies and dementia in PD. In conclusion, we have shown that cortical astrogliosis is not associated with the cognitive decline in Lewy body-related dementia.…”
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