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621
Dextran-Polyacrylamide as Matrices for Creation of Anticancer Nanocomposite
Published 2017-01-01“…The polymer nanoparticles loaded with cisplatin at different concentrations from 0.1 to 10 μg/mL yielded dose-dependent decrease in viability of chronic myelogenous leukemia and histiocytic lymphoma cells. The lowest percentage of viable cells was observed for lymphoma cells (22%). …”
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622
A Rare Presentation of Lymphoma of the Cervix with Cross-Sectional Imaging Correlation
Published 2014-01-01“…A 43-year-old asymptomatic female with a history of dual hit blastic B-cell lymphoma/leukemia in complete remission presented with an incidental cervical mass, which was initially felt to represent a cervical fibroid on computed tomography (CT). …”
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623
Translocation (6;15)(q12;q15): A Novel Mutation in a Patient with Therapy-Related Myelodysplastic Syndrome
Published 2015-01-01“…We present a unique case of a patient who initially presented with acute myeloid leukemia (AML) with a normal karyotype and FLT3-ITD and NPM1 mutations. …”
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624
The AST/ALT (De Ritis) ratio as a significant prognostic factor in myelodysplastic syndrome
Published 2024-12-01“…The clinical, laboratory, and follow-up data of patients with MDS were collected, while the relationship between AST/ALT ratio and overall survival (OS) and leukemia-free survival (LFS) were also analyzed. Results: The results showed that higher AST/ALT ratio was associated with higher age, β2-microglobulin level, and number of co-mutations (>4). …”
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625
Evaluation of the practical application of the category-imbalanced myeloid cell classification model.
Published 2025-01-01“…The incidence of acute myeloid leukemia (AML) is increasing annually, and timely diagnostic and treatments can substantially improve patient survival rates. …”
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626
Biochemical characterization of the human ubiquitous glucose‐6‐phosphatase in neutrophil granulocytes
Published 2025-02-01“…Using the HL‐60 promyelocytic leukemia cell line as an in vitro model system for myeloid differentiation, we found no significant differences in enzyme expression and phosphatase activity latency between undifferentiated and differentiated cells. …”
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627
Optimal Molecular Methods in Detecting p190BCR-ABL Fusion Variants in Hematologic Malignancies: A Case Report and Review of the Literature
Published 2015-01-01“…Patients with BCR-ABL1 positive hematologic malignancies and Philadelphia-like B-lymphoblastic leukemia (B-ALL) are potential candidates for targeted therapy with tyrosine kinase inhibitors (TKI). …”
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628
Colonization of a Central Venous Catheter by the Hyaline Fungus Fusarium solani Species Complex: A Case Report and SEM Imaging
Published 2013-01-01“…The case of a 13-year-old boy under treatment for acute lymphoblastic leukemia is presented. The boy was readmitted to the Pediatric Ward for intermittent fever of unknown origin. …”
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629
β2microglobulin levels, clinical and sociodemographic variables in patients with recently diagnosed chronic lymphoproliferative syndrome
Published 2023-03-01“…The series was made up of all adult patients (universe 50) recently diagnosed (without starting specific antitumor therapy) of multiple myeloma, chronic lymphoid leukemia, non-Hodgkin lymphoma and Hodgkin lymphoma, admitted to the Hematology Service of the Dr. …”
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630
Targeting ceramide transfer protein sensitizes AML to FLT3 inhibitors via a GRP78-ATF6-CHOP axis
Published 2025-02-01“…Combining CERT inhibitor with FLT3 inhibitor exhibits synergistic effects on FLT3-ITD mutated acute myeloid leukemia (AML) cells. Additionally, co-treatment of HPA-12 and Crenolanib is effective in FLT3-ITD+ and FLT3-TKD+ AML patients. …”
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631
Rural-Urban Disparity in Premature Cancer Mortality in Young People Aged 15–44 Years in China, 2004–2021
Published 2025-02-01“…The five leading types of cancer deaths consistently remained liver, lung, leukemia, stomach, and other cancers in both rural and urban areas after 2013.ConclusionOur findings indicate that there were rural-urban disparities in cancer mortality in young people, which showed a different pattern compared to other age groups. …”
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632
FHL1 as a prognostic biomarker and therapeutic target in acute promyelocytic leukaemia
Published 2025-01-01“…Abstract Acute myeloid leukemia (AML) has a poor prognosis and high heterogeneity. …”
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633
Genomic Amplification of an Endogenous Retrovirus in Zebrafish T-Cell Malignancies
Published 2012-01-01“…Based on these data and ZFERV’s phylogenetic relation to viruses of the murine-leukemia-related virus class of gammaretroviridae, we posit that ZFERV may be oncogenic via an insertional mutagenesis mechanism.…”
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634
Therapeutic Mechanism and Effect of Camptothecin on Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice
Published 2021-01-01“…It possesses various antitumor activities and is mainly used in the treatment of colon, ovarian, liver, and bone cancers as well as leukemia. CPT inhibits the expressions of inflammatory genes and can prevent death from chronic inflammation. …”
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635
Diagnosis of Vitreoretinal Aspergillosis with Transvitreal Retinochoroidal Biopsy
Published 2018-01-01“…Our case is a 48-year-old male with B-cell acute lymphoblastic leukemia that presented with counting fingers vision, redness, and tearing of the left eye. …”
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636
Impact of Childhood Cancer on Family Functioning and Family Quality of Life in the Western Region of Saudi Arabia
Published 2024-01-01“…Healthcare and social systems may have to consider the impact of childhood cancer in the care plans of the patients. Result. Leukemia represents the highest disease prevalence followed by brain tumor. …”
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637
Preclinical Evaluation of a Bone-Marrow Autograft Culture Procedure for Generating Lymphokine-Activated Killer Cells in Vitro
Published 1992-01-01“…Despite the use of high dose chemoradiotherapy for the treatment of acute leukemia. relapse continues to be a major cause of death in patients given an autologous bone marrow transplant. …”
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638
Bcl-2 and Bcl-xL in Diabetes: Contributions to Endocrine Pancreas Viability and Function
Published 2025-01-01“…Type 1 (T1D) and type 2 diabetes (T2D), the most common forms of diabetes, are characterized by the loss of functional pancreatic β-cells, mostly due to apoptosis. B-cell leukemia/lymphoma 2 (Bcl-2) and B-cell lymphoma-extra large (Bcl-xL), two anti-apoptotic proteins belonging to the Bcl-2 family, are crucial for regulating the intrinsic pathway of apoptosis. …”
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639
The Impact of Bioactive Lipids on Cardiovascular Development
Published 2011-01-01“…SPC induces mesodermal differentiation of mouse ES cells and differentiation of promyelocytic leukemia cells, by a mechanism being critically dependent on MEK-ERK signalling. …”
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640
LIF Upregulates Expression of NK-1R in NHBE Cells
Published 2006-01-01“…Leukemia inhibitory factor (LIF), a cytokine at the interface between neurobiology and immunology, is mainly mediated through JAK/STAT pathway and MAPK/ERK pathway. …”
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