CSF3R Gln776X and ASXL1 mutations in multiple myeloma associated with chronic neutrophilic leukemia: case report and literature review by Ying Han, Yajun Shi, Tao Wu, Jinmao Zhou

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Dental and Periodontal Treatment Need after Dental Clearance Is Not Associated with the Outcome of Induction Therapy in Patients with Acute Leukemia: Results of a Retrospective Pilot Study by Gerhard Schmalz, Lulzim Tulani, Rilana Busjan, Rainer Haak, Tanja Kottmann, Lorenz Trümper, Justin Hasenkamp, Dirk Ziebolz

“…This retrospective pilot study aimed to detect whether remaining dental/periodontal treatment need and periodontal inflammation after dental clearance would be associated with the initial therapy outcome of adult patients with acute leukemia undergoing induction chemotherapy. Different parameters were assessed from the patients’ records: initial blood parameters, blood parameters during initial chemotherapy, leukemia/therapy related complaints, duration of fever, microbiological findings (blood and urine), as well as patients’ survival. …”
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Global leukemia burden and trends: a comprehensive analysis of temporal and spatial variations from 1990—2021 using GBD (Global Burden of Disease) data by Pengyu Huang, Jie Zhang

Subjects: “…Leukemia…”
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Immunogenicity of Pfizer mRNA COVID-19 Vaccination Followed by J&J Adenovirus COVID-19 Vaccination in Two Patients with Chronic Lymphocytic Leukemia by Zoe L. Lyski, Myung Sun Kim, David Xthona Lee, David Sampson, Hans-Peter Raué, Vikram Raghunathan, Debbie Ryan, Amanda E. Brunton, Mark K. Slifka, William B. Messer, Stephen E. Spurgeon

“…Individuals with chronic lymphocytic leukemia (CLL) have significant immune disfunction, often further disrupted by treatment. …”
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The Partial Duplication of the 5′ Segment of KMT2A Revealed KMT2A-MLLT10 Rearrangement in a Boy with Acute Myeloid Leukemia by Hiroko Fukushima, Toru Nanmoku, Sho Hosaka, Yuni Yamaki, Nobutaka Kiyokawa, Takashi Fukushima, Ryo Sumazaki

“…The duplication of 5′ segment of KMT2A is a rare molecular event in childhood leukemia, and the influence on prognosis is unknown. …”
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Sepsis due to Erysipelothrix rhusiopathiae in a Patient with Chronic Lymphocytic Leukemia Associated with Bronchopneumonia due to PSeudomonas aeruginosa And Escherichia coli: A Case Report by Victoria Bîrlutiu

“…INTRODUCTION: The present report describes a case of sepsis due to Erysipelothrix rhusiopathiae in a patient with B-cell chronic lymphocytic leukemia with no animal exposure, associated with concomitant bronchopneumonia due to Pseudomonas aeruginosa and Escherichia coli.…”
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De Novo Acute Myeloid Leukemia with Combined CBFB-MYH11 and BCR-ABL1 Gene Rearrangements: A Case Report and Review of Literature by Venkata Rakesh Sethapati, Ra’ed Jabr, Leyla Shune, Wissam El Atrouni, Patrick R. Gonzales, Wei Cui, Shivani Golem

“…Acute myeloid leukemia (AML) with inv(16)(p13.1q22) resulting in CBFB-MYH11 fusion is associated with a favorable prognosis. …”
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HSP90 inhibitors promote cell death by degrading Met and BCR::ABL1 in both imatinib-resistant and -sensitive chronic myeloid leukemia cells by Masanobu Tsubaki, Taira Matsuo, Rie Komori, Noriaki Nagai, Tetsushi Yamamoto, Shozo Nishida

Subjects: “…Chronic myeloid leukemia…”
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Efficacy and safety of currently approved and lower starting doses of inotuzumab ozogamicin in adult patients with relapsed or refractory acute lymphoblastic leukemia: a phase IV study by Muhit Özcan, Ryan D. Cassaday, Ewa Zarzycka, Erik Vandendries, Fan Zhang, Ying Chen, Alejandra Nieto, Fatih Demirkan, Pau Montesinos, Fevzi Altuntas

“… Inotuzumab ozogamicin (InO) is approved for treatment of relapsed/refractory acute lymphoblastic leukemia (R/R ALL). Previous studies reported higher rates of post– hematopoietic stem cell transplant (HSCT) hepatic sinusoidal obstruction syndrome (SOS) in patients receiving InO versus chemotherapy prior to HSCT. …”
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Decitabine Compared with Low-Dose Cytarabine for the Treatment of Older Patients with Newly Diagnosed Acute Myeloid Leukemia: A Pilot Study of Safety, Efficacy, and Cost-Effectiveness by Linu A. Jacob, S. Aparna, K. C. Lakshmaiah, D. Lokanatha, Govind Babu, Suresh Babu, Sandhya Appachu

“…The incidence of Acute Myeloid Leukemia (AML) increases progressively with age and its treatment is challenging. …”
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Successful Long-Term Use of Eltrombopag in a Patient with Refractory Severe Thrombocytopenia Associated with Chronic Lymphocytic Leukemia That Allowed Oral Anticoagulant Treatment for Severe Cardiomyopathy by Juárez Salcedo Luis Miguel, Gil-Fernández Juan José

“…Autoimmune cytopenias (AICs) are frequently associated with chronic lymphocytic leukemia (CLL). The most common of these AICs is autoimmune hemolytic anemia (AIHA); the second most is immune thrombocytopenia (ITP). …”
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Integrating rapamycin with novel PI3K/Akt/mTOR inhibitor microRNAs on NOTCH1-driven T-cell acute lymphoblastic leukemia (T-ALL) by Fateme Arjmand, Samaneh Shojaei, Mitra Khalili, Hossein Dinmohammadi, Behzad Poopak, Samira Mohammadi-Yeganeh, Yousef Mortazavi

Subjects: “…t-cell acute lymphoblastic leukemia…”
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Global, regional, and national burden of children and adolescents with acute lymphoblastic leukemia from 1990 to 2021: a systematic analysis for the global burden of disease study 2021 by Lei Wang, Xue Yao, Linhua Yang

“…BackgroundAcute lymphoblastic leukemia (ALL) is a common cancer in children and adolescents, severely affecting their survival and health. …”
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Dexamethasone added to induction and post-remission therapy in older patients with newly diagnosed acute myeloid leukemia: a multicenter, phase II trial (DEXAML-02) by Sarah Bertoli, Emilie Bérard, Pierre Peterlin, Romain Guieze, Yohan Desbrosses, Yosr Hicheri, Omar Benbrahim, Martin Carre, Corentin Orvain, Anne Banos, Marc Bernard, Emmanuel Gyan, Alain Saad, Safia Chebrek, Gabrielle Roth Guepin, Veronique Dorvaux, Laurence Sanhes, Maria Pilar Gallego-Hernanz, Carole Exbrayat, Laure Vincent, Chantal Himberlin, Célestine Simand, Norbert Vey, Cindy Fenoll, Ariane Mineur, Anne Huynh, Francois Vergez, Isabelle Luquet, Laetitia Largeaud, Eric Delabesse, Arnaud Pigneux, Christian Récher, French Innovative Leukemia Organization FILO

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Pathogenetic, Clinical, and Prognostic Features of Adult t(4;11)(q21;q23)/MLL-AF4 Positive B-Cell Acute Lymphoblastic Leukemia by F. Marchesi, K. Girardi, G. Avvisati

“…This form of leukemia is universally recognized as high-risk leukemia and treatment intensification with allogeneic hematopoietic stem cell transplantation (HSCT) in first complete remission (CR) could be a valid option to improve prognosis, but data obtained from the literature are controversial. …”
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Phylogeny-Directed Search for Murine Leukemia Virus-Like Retroviruses in Vertebrate Genomes and in Patients Suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Prostate Cancer by Jonas Blomberg, Ali Sheikholvaezin, Amal Elfaitouri, Fredrik Blomberg, Anna Sjösten, Johan Mattson Ulfstedt, Rüdiger Pipkorn, Clas Källander, Christina Öhrmalm, Göran Sperber

“…Gammaretrovirus-like sequences occur in most vertebrate genomes. Murine Leukemia Virus (MLV) like retroviruses (MLLVs) are a subset, which may be pathogenic and spread cross-species. …”
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Efficacy of Venetoclax and Dexamethasone in Refractory IgM Primary Plasma Cell Leukemia with t(11;14) and TP53 Mutation: A Case Report and Literature Review by Salimah Valliani, Mir Ali, Omar Mahmoo, Sanjay Hinduja, Calvin K. Chen, Lloyd Damon, Haifaa Abdulhaq

“…Primary plasma cell leukemia (pPCL) is an uncommon disease. IgM multiple myeloma (MM) is an infrequent subtype that accounts for less than 1 percent of MM cases. …”
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MPO Expression of Background Neutrophils in MPO Negative Acute Promyelocytic Leukemia, An Easy Clue to Corroborate a Challenging Diagnosis: A Case Report and Review of Literature by Kritika Krishnamurthy, Jui Choudhuri, K. H. Ramesh, Yanhua Wang

“…Acute promyelocytic leukemia (APL) is characterized by the pathogenic driver fusion transcript PML-RARA resulting from the t(15;17) translocation. …”
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Immune‐dysregulation harnessing in myeloid neoplasms by Mohammad Jafar Sharifi, Ling Xu, Nahid Nasiri, Mehnoosh Ashja‐Arvan, Hadis Soleimanzadeh, Mazdak Ganjalikhani‐Hakemi

Subjects: “…acute myeloid leukemia…”
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A novel perspective on survival prediction for AML patients: Integration of machine learning in SEER database applications by Zheng-yi Jia, Maierbiya Abulimiti, Yun Wu, Li-na Ma, Xiao-yu Li, Jie Wang

Subjects: “…Acute myeloid leukemia…”
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