An LNP-mRNA vaccine modulates innate cell trafficking and promotes polyfunctional Th1 CD4+ T cell responses to enhance BCG-induced protective immunity against Mycobacterium tubercu... by Hannah Lukeman, Hareth Al-Wassiti, Stewart A. Fabb, Leonard Lim, Trixie Wang, Warwick J. Britton, Megan Steain, Colin W. Pouton, James A. Triccas, Claudio Counoupas

Subjects: Get full text

Implications of Anaphylaxis Following mRNA-LNP Vaccines: It Is Urgent to Eliminate PEG and Find Alternatives by Jinxing Song, Dihan Su, Hongbing Wu, Jeremy Guo

Subjects: “…LNP…”
Get full text

Development and efficacy of a novel mRNA cocktail for the delivery of African swine fever virus antigens and induction of immune responses by Xing Hu, Cong Liu, Nino Rcheulishvili, Yunzhi Wang, Ting Xiong, Fengfei Xie, Xingyun Wang, Ruiai Chen, Peng George Wang, Yunjiao He

Subjects: Get full text

Immune Modulation with Oral DNA/RNA Nanoparticles by Ulpan Kart, Aigul Raimbekova, Sergey Yegorov, Gonzalo Hortelano

Subjects: Get full text

Circular mRNA-LNP vaccine encoding self-assembled E2-TMD-mi3 nanoparticles licit enhanced CSFV-specific immunity over commercial subunit vaccine by Chunxi Liu, Weifeng Zhai, Wenhao Nie, Conghao Zhong, Feifei Diao, Bo Yin, Bo Yin, Bo Yin

Subjects: Get full text

A factorial design-optimized microfluidic LNP vaccine elicits potent magnesium-adjuvating cancer immunotherapy by Yongyi Xie, Jiaxin Guo, Jialin Hu, Yuan Li, Zhongqian Zhang, Yongcheng Zhu, Fei Deng, Jialong Qi, You Zhou, Wenjie Chen

Subjects: “…LNP…”
Get full text

A lyophilizable LNP vaccine enables STING-reinforced postoperational adjuvant immunotherapy by Yi Yang, Jiaxin Guo, Jialong Qi, Wenxia Deng, Jialin Hu, Muhammad Waqqas Hasan, Fei Deng, You Zhou, Zhengji Song, Wei Deng, Wenjie Chen

Subjects: “…Lyophilizable LNP vaccine…”
Get full text

LNP-enclosed NamiRNA inhibits pancreatic cancer proliferation and migration via dual pathways by Chao Yu, Zhou Fang, Qingyu Xie, Zhuo Wu, Peixian Huang, Jinlong Yu, Rufu Chen

Subjects: Get full text

Acute Myeloid Leukemia with NUP98: : LNP1 Fusion Mimicking Chronic Myeloid Leukemia by Haiyang Wang, Yu Peng, Zailin Yang

Subjects: Get full text

Macrophage Inhibitor Clodronate Enhances Liver Transduction of Lentiviral but Not Adeno-Associated Viral Vectors or mRNA Lipid Nanoparticles in Neonatal and Juvenile Mice by Loukia Touramanidou, Sonam Gurung, Claudiu A. Cozmescu, Dany Perocheau, Dale Moulding, Patrick F. Finn, Andrea Frassetto, Simon N. Waddington, Paul Gissen, Julien Baruteau

Subjects: Get full text

Impact of Extended Dosing Intervals and Ipsilateral Versus Contralateral Boosting on mRNA Vaccine Immunogenicity in Mice by Bin Lu, Omkar Chaudhary, Balaji Banoth, Janhavi Nadkarni, Wei Zong, Emilie Mausser, Hillary Danz, Mona Motwani, Sophie Ruiz, Donghui Zhang, Gopinath Nageshwaran, Bachra Rokbi, William Warren, Frank DeRosa, Sudha Chivukula

Subjects: “…mRNA-LNP…”
Get full text

Development of a Cationic Polymeric Micellar Structure with Endosomal Escape Capability Enables Enhanced Intramuscular Transfection of mRNA-LNPs by Siyuan Deng, Han Shao, Hongtao Shang, Lingjin Pang, Xiaomeng Chen, Jingyi Cao, Yi Wang, Zhao Zhao

Subjects: “…mRNA-LNP…”
Get full text

mRNA-LNP Vaccines Targeting SmpA-PLD and OmpK-Omp22 Induce Protective Immunity Against <i>Acinetobacter baumannii</i> by Cong Liu, Xingyun Wang, Yueling Zheng, Xingyue Gao, Jiahui Jin, Xing Cheng, Yunjiao He, Peng George Wang

Subjects: Get full text

Lipid Nanoparticles Enable Efficient In Vivo DNA Knock-In via HITI-Mediated Genome Editing by Jun Hirose, Emi Aizawa, Shogo Yamamoto, Mingyao Xu, Shigenori Iwai, Keiichiro Suzuki

Subjects: Get full text

Targeted mRNA delivery with bispecific antibodies that tether LNPs to cell surface markers by Bettina Dietmair, James Humphries, Timothy R. Mercer, Kristofer J. Thurecht, Christopher B. Howard, Seth W. Cheetham

Subjects: Get full text

Methylprednisolone substituted lipid nanoparticles deliver C3 transferase mRNA for combined treatment of spinal cord injury by Haoru Dong, Zongxing He, Shiyi Cai, Haiqiang Ma, Lili Su, Jianfeng Li, Huiying Yang, Rong Xie

Subjects: Get full text

Machine learning-assisted design of immunomodulatory lipid nanoparticles for delivery of mRNA to repolarize hyperactivated microglia by Mehrnoosh Rafiei, Akbar Shojaei, Ying Chau

Subjects: Get full text

Brain targeted lipid nanoparticles with Hv1 inhibitors alleviate neuroinflammation post-ischemic stroke by Zeyu Yang, Lei Jin, Longxiang Li, Yu Wu, Wenchao Liu, Xin Feng, Liyan Li, Fa Jin, Yiming Bi, Ran Li, Shenquan Guo, Yanan Wang, Boyang Wei, Yanchao Liu, Xifeng Li, Chuanzhi Duan

Subjects: Get full text

An mRNA vaccine encoding the SARS-CoV-2 Omicron XBB.1.5 receptor-binding domain protects mice from the JN.1 variantResearch in context by Ryuta Uraki, Maki Kiso, Mutsumi Ito, Seiya Yamayoshi, Peter Halfmann, Shilpi Jain, Mehul S. Suthar, Tiago J.S. Lopes, Nao Jounai, Kazuki Miyaji, Fumihiko Takeshita, Yoshihiro Kawaoka

Subjects: Get full text

EIF4E-mediated biogenesis of circPHF14 promotes the growth and metastasis of pancreatic ductal adenocarcinoma via Wnt/β-catenin pathway by Zhou Fang, Zhuo Wu, Chao Yu, Qingyu Xie, Liangtang Zeng, Rufu Chen

Subjects: Get full text