Multi-Omics Analysis of Mouse Fecal Microbiome Reveals Supplier-Dependent Functional Differences and Novel Metagenome-Assembled Genomes by Zachary L. McAdams, Susheel Bhanu Busi, Kevin L. Gustafson, Nathan Bivens, Craig L. Franklin, Paul Wilmes, Aaron C. Ericsson

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Effect of Shipping on the Microbiome of Donor Mice Used to Reconstitute Germ-Free Recipients by Zachary L. McAdams, Jared Yates, Giedre Turner, Rebecca A. Dorfmeyer, Mary Wight-Carter, James Amos-Landgraf, Craig L. Franklin, Aaron C. Ericsson

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Mapping the genetic landscape establishing a tumor immune microenvironment favorable for anti-PD-1 response by Daniel A. Skelly, John P. Graham, Mingshan Cheng, Mayuko Furuta, Andrew Walter, Thomas A. Stoklasek, Hongyuan Yang, Timothy M. Stearns, Olivier Poirion, Ji-Gang Zhang, Jessica D.S. Grassmann, Diane Luo, William F. Flynn, Elise T. Courtois, Chih-Hao Chang, David V. Serreze, Francesca Menghi, Laura G. Reinholdt, Edison T. Liu

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P668: Assessing the utility of long-read genome sequencing in rare pediatric disorders by Liz Werren, Purva Vats, Gabriel Rech, Cameron King, Michael Peracchio, Elizabeth Charnysh, Peter Audano, Peter Robinson, Louisa Kalsner, Adam Matson, Melissa Kelly, Mark Adams

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Alternating hemiplegia of childhood associated mutations in Atp1a3 reveal diverse neurological alterations in mice by Markus Terrey, Georgii Krivoshein, Scott I. Adamson, Elena Arystarkhova, Laura Anderson, John Szwec, Shelby McKee, Holly Jones, Sara Perkins, Vijay Selvam, Pierre-Alexandre Piec, Dweet Chhaya, Ari Dehn, Aamir Zuberi, Stephen A. Murray, Natalia S. Morsci, Kathleen J. Sweadner, David A. Knowles, Else A. Tolner, Arn M.J.M. van den Maagdenberg, Cathleen M. Lutz

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Transcripts with high distal heritability mediate genetic effects on complex metabolic traits by Anna L. Tyler, J. Matthew Mahoney, Mark P. Keller, Candice N. Baker, Margaret Gaca, Anuj Srivastava, Isabela Gerdes Gyuricza, Madeleine J. Braun, Nadia A. Rosenthal, Alan D. Attie, Gary A. Churchill, Gregory W. Carter

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Mouse Genome Informatics: Mapping/Homology Data by D. Bradt, C.J. Bult, J.A. Blake, J.A. Kadin, J.E. Richardson, J.T. Eppig

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Species- and strain-specific microbial modulation of interferon, innate immunity, and epithelial barrier in 2D air–liquid interface respiratory epithelial cultures by Mian Horvath, Ruoyu Yang, Diana Cadena Castaneda, Megan Callender, Elizabeth S. Aiken, Anita Y. Voigt, Ryan Caldwell, José Fachi, Blanda Di Luccia, Zoe Scholar, Peter Yu, Andrew Salner, Marco Colonna, Karolina Palucka, Julia Oh

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O16: Preclinical development of a gene therapy for Ogden syndrome, using new mouse models of the disease by Gholson Lyon, Kathy Snow, Yaned Gaitan, Ethan Saville, Stephen Kneeland, Hye Ri Kang, Steven Gray, Elaine Marchi, Cat Lutz, Steve Murray

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Effective integration of multi-omics with prior knowledge to identify biomarkers via explainable graph neural networks by Rohit K. Tripathy, Zachary Frohock, Hong Wang, Gregory A. Cary, Stephen Keegan, Gregory W. Carter, Yi Li

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P518: Preaching to the choir: Genetics providers must break out of their silos to integrate genomics in all of medicine by Kalisi Logan, Emily Edelman, Kate Reed, Paige Tanner, Laura Ciaccia West

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Mouse Model Resources for Vision Research by Jungyeon Won, Lan Ying Shi, Wanda Hicks, Jieping Wang, Ronald Hurd, Jürgen K. Naggert, Bo Chang, Patsy M. Nishina

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Antisense oligonucleotide-mediated TRA2β poison exon inclusion induces the expression of a lncRNA with anti-tumor effects by Nathan K. Leclair, Mattia Brugiolo, SungHee Park, Maeva Devoucoux, Laura Urbanski, Brittany L. Angarola, Marina Yurieva, Olga Anczuków

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HAND1, partially mediated through ape-specific LTR binding, is essential for human extra-embryonic mesenchyme derivation from iPSCs by Zukai Liu, Yuliana Tan, William F. Flynn, Lili Sun, Ponthip Pratumkaew, Juliana Alcoforado Diniz, Nelio A.J. Oliveira, Justin A. McDonough, William C. Skarnes, Paul Robson

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Metallothionein 1 mediates growth and survival of <i>Dnmt3a;Npm1</i>-mutant acute myeloid leukemia by Patricia A. Colom Díaz, Jayna J. Mistry, Kira A. Young, Chih-Hsing Chou, Nathan Boyer, Ross L. Levine, Nathan Salomonis, H. Leighton Grimes, Jennifer J. Trowbridge

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Caspase-11 drives macrophage hyperinflammation in models of Polg-related mitochondrial disease by Jordyn J. VanPortfliet, Yuanjiu Lei, Muthumeena Ramanathan, Camila Guerra Martinez, Jessica Wong, Tim J. Stodola, Brian R. Hoffmann, Kathryn Pflug, Raquel Sitcheran, Stephen C. Kneeland, Stephen A. Murray, Peter. J. McGuire, Carolyn L. Cannon, A. Phillip West

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Regulation of Mucosal Immune Responses – The Missing Link in IBD? by Charles O Elson, Robert P Mccabe, Kenneth W Beagley, Almaz Sharmanov, Steven L Brandwein, Ben U Ridwan, Casey Weaver, R Patrick Bucy, Jerry R Mcghee, John Sundberg, Edward Birkenmeier

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Genetic context modulates aging and degeneration in the murine retina by Olivia J. Marola, Michael MacLean, Travis L. Cossette, Cory A. Diemler, Amanda A. Hewes, Alaina M. Reagan, Jonathan Nyandu Kanyinda, Daniel A. Skelly, Gareth R. Howell

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TEAL-Seq: targeted expression analysis sequencing by Georgia Doing, Priya Shanbhag, Isaac Bell, Sara Cassidy, Efthymios Motakis, Elizabeth Aiken, Julia Oh, Mark D. Adams

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Quantitative PCR genotyping assay for the Ts65Dn mouse model of Down syndrome by Dong P. Liu, Cecilia Schmidt, Timothy Billings, Muriel T. Davisson

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