Incidence and risk factors for mortality of vertebral osteomyelitis: a retrospective analysis using the Japanese diagnosis procedure combination database by Hideo Yasunaga, Hirotaka Chikuda, Kiyohide Fushimi, Hiromasa Horiguchi, Toru Akiyama, Kazuo Saita

“…A higher rate of in-hospital mortality was significantly associated with haemodialysis use (ORs, 10.56 (95% CI 8.12 to 13.74)), diabetes (2.37 (1.89 to 2.98)), liver cirrhosis (2.63 (1.49 to 4.63)), malignancy (2.68, (2.10 to 3.42)) and infective endocarditis (3.19 (1.80 to 5.65)).Conclusions Our study demonstrates an increasing incidence of VO, and defines risk factors for death with a nationwide database. …”
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Protocol for a multicentre randomised controlled trial examining the effects of temporarily pausing Bruton tyrosine kinase inhibitor therapy to coincide with SARS-CoV-2 vaccination... by Abhishek Abhishek, Jonathan A Cook, Helen M Parry, Anne Francis, Lelia Duley, Vicki S Barber, Paul Moss, Nicholas Peckham

“…The model will be adjusted for randomisation factor (first line or subsequent line of therapy), and prior infection status obtained from prerandomisation antinucleocapsid antibodies as fixed effects.Ethics and dissemination This study has been approved by Leeds East Research Ethics Committee and Health Research Authority (REC Reference:22/YH/0226, IRAS ID: 319057). …”
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Effects of perioperative treatment of resectable adenocarcinoma of esophagogastric junction by immunotherapy (Adebrelimab) combined with chemotherapy (XELOX): protocol for a single... by Yingyi Li, Yuqin Cao, Xipeng Wang, Chengqiang Li, Liqin Zhao, Hecheng Li

“…The exploratory outcomes are the biomarkers related to therapeutic efficacy, such as PD-L1 expression, microsatellite instability (MSI), tumor mutational burden(TMB), Epstein-Barr virus(EBV) infection, and circulating tumor DNA(ctDNA). Discussion This trail aims to verify the efficacy and safety of the perioperative treatment regimen of anti-PD-L1 (Adebrelimab) combined with chemotherapy (capecitabine plus oxaliplatin, XELOX) for patients with resectable AEG. …”
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Evaluation of 902 Total Abdominal Hysterectomies Performed for Benign Reasons by Fazilet Kübra Boynukalın, Ömer Tolga Güler, Mehmet Coşkun, Özgür Özyüncü, Nasuh Utku Doğan

“…Postoperative complications were seen in 17.1% of the patients and the most frequent postoperative complications were febrile morbidity and wound infection (10.1% and 4.3%, respectively). Preoperative and postoperative mean hemoglobin values were 11.9 and 10.3 gr/dL, respectively, and 7.5% of the patients received erythrocyte transfusion postoperatively. …”
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Community-Based Assessment of Knowledge, Attitudes, and Practices Towards COVID-19: an Epidemiological Survey in Kurdistan Region, Iraq by Zhino Rawf Ali, Bayan Omar Sharif, Aram Salih Mohammed Amin Kamali, Varin Tofiq Abbas, Azad Karim Ahmed, Shaho Osman Mahmood, Chiman Jamal ahmed, Sarwat Ahmed Abdulqader

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Long-Term Monitoring of Liver Fibrosis and Steatosis in Patients with Chronic Hepatitis C after Achieving a Sustained Virologic Response to Antiviral Therapy by K. R. Dudina, P. A. Belyy, I. V. Maev, N. Kh. Safiullina, E. A. Klimova, S. A. Shutko, O. O. Znoyko, N.  D. Yushchuk

“…The data obtained indicate the feasibility of routine diagnosis of both fibrosis and steatosis of the liver in the management of patients with chronic HCV infection before and after successful antiviral therapy.…”
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iPSC-derived exosomes as amphotericin B carriers: a promising approach to combat cryptococcal meningitis by Jingyu Zhao, Jingyu Zhao, Wei Fang, Yangjie Gao, Jiquan Chen, Guizhen Wang, Julin Gu

“…In a C57BL/6 J mouse model of cryptococcal infection, treatment groups (AmB, iPSC-Exo/AmB, and iPSC-Exo) were administered corresponding drugs, with blood and brain samples collected for analysis. …”
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Exploring healthcare workers’ immunisation behaviour towards COVID-19 vaccines through psychological patterns by Nour El Houda Benkaddour, Sara Ramdani, Hind Khalil, Asmae Lekfif, Naima Abda, Bouchra Oneib, Yassamine Bentata

“…Furthermore, the analysis showed that vaccination profile (p = 0.02), accepting the vaccine for any reason other than its accessibility (p = 0.03) and having a previous coronavirus disease 2019 infection (p = 0.03), were significantly associated with stress. …”
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Asymptomatic testing people for SARS-CoV-2 in healthcare facilities: A systematic review by Olabisi A. Oduwole, Glory Bassey, Grace Esebanmen, Samuel Shoyinka, Johnsolomon Ohenhen, Elise Cogo, Nicholas Henschke, Eleanor Ochodo, Martin M. Meremikwu

“…Background: Asymptomatic testing involves the process whereby individuals who do not show symptoms of COVID-19 are tested for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection using any of the available laboratory test techniques. …”
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Profile of Egyptian pediatrics with COVID-19: insights from healthcare providers in Egypt by Salma ZEl Houchi, Hanaa I. Rady, Iman Iskander, Tamer Abdel Hamid, Salma Abdelrehim Seddik, Amira Aly Hegazy, Ahmed Taha Aboushady, Mohamed Eissa, Sherine Khamis Hussein, Dina Hanoura, Miriam Magdy Aziz, Remon Magdy, Heba Ahmed ElAwady, Esraa A. Elmazzahy

“…This study aims to explore the epidemiological patterns, clinical features, laboratory and radiological characteristics, and outcomes of COVID-19 infection in a group of Egyptian children (≤ 18 years). …”
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Clinical and endoscopical and morphofunctional scores in evaluation of development of gastroesophageal reflux disease in various age groups by M. A. Osadchuk, A. M. Zolotovitskaya, N. V. Kireyeva, S. N. Nikolenko, I. M. Kvetnoy

“…The catarrhal form of GERD at middle-aged patients develops on a background of gastritis with signs of atrophy, associated to H. pylori infection, contaminations of distal esophagus by H. pylori and foci of gastric metaplasia, dysfunction of motility of upper regions of the gut on a background of hyperplasia of NO-synthase and endothelin-1-producing cells of the esophagus and the stomach. …”
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Dietary and environmental factors affecting the dynamics of the gut bacteria in Tibetan Awang sheep (Ovis aries) across divergent breeding models by Yuhao Wang, Xinping Wang, Yirong Wang, Yirong Wang, Songyu Liao, Zhaxi Pubu, Jiangcuo Silang, Lixu Chai, Siyue Zhao, Siyue Zhao

“…An abnormally high abundance of Acinetobacter indicated a potential risk of Acinetobacter infection in the fully captive group. The environmental association analysis exhibited that meadows diet (R2 = 0.938, Pr[>r] = 0.001) and altitude (R2 = 0.892, Pr[>r] = 0.001) had significant effects on the dominant genera, explaining a substantial proportion of the total variation in community composition.DiscussionOur study indicated that breeding conditions significantly impact the gut microbiota of Awang sheep. …”
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Attendance of Patients with ophthalmological problems about Eye Protection from UV/blue Light Radiation from Sun light and Electronic Devices in Sulaimani City by Salah Qadir Mahmood, Muhammad Babakir-Mina, Salar Ibrahim Ali, Abdulrahman M. Ibrahem, Bakhtyar Kamal Talabany

“…Finally, most of the patients with dry eyes, eye/lid infection and glaucoma and cataract had significantly more practices for taking visual breaks when using electronic devices. …”
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Staphylococcus aureus induces mitophagy via the HDAC11/IL10 pathway to sustain intracellular survival by Yaji Yang, Haotian Zhou, Feilong Li, Yanhao Zhang, Jianye Yang, Yidong Shen, Ning Hu, Quanming Zou, Leilei Qin, Hao Zeng, Wei Huang

“…Additionally, we discovered that the transcriptional repressor of IL10, HDAC11, was significantly downregulated during S. aureus infection. Overexpression of HDAC11 and the use of the autophagy activator rapamycin further validated that the HDAC11/IL10 axis regulates mitophagy via the mTOR pathway, which is essential for supporting S. aureus intracellular survival. …”
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A CD36-based prediction model for sepsis-induced myocardial injury by Yun Xie, Hui Lv, Daonan Chen, Peijie Huang, Zhigang Zhou, Ruilan Wang

“…No significant differences in CD36 levels were observed between groups with lung and stomach infections or between Gram-positive and Gram-negative infection groups. …”
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Predicting dengue incidence in high-risk areas of China through the integration of Southeast Asian and local meteorological factors by Shaowei Sang, Yiguan Wang, Qiyong Liu, Peng Chen, Chuanxi Li, Anran Zhang

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Laser Based ¹³C-urea Breath Test in Quantitative Assessment of Bacterial Colonization, Severity of Inflammation and Atrophy in Gastric Mucosa by E. V. Stepanov, V. T. Ivashkin

“…Based on the results of 13C-UDT DLS, H. рylori infection was detected in 447 patients. H. рylori was not found in erosive gastritis in 15 %, erosive duodenitis in 21 % and chronic non-erosive gastritis in 23 %. …”
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Contemporary Management of Patients With Chagas Cardiomyopathy in Bolivia by Evan Czulada, BS, Sascha Bercovitch, BA, Yazan Alshawkani, MD, Natalia Noya Weise, MD, Adriana E. Hernani Rodrigo, BS, Ronald Gustavo Durán Saucedo, MD, Marcelo Buhezo Chamón, MD, Robert H. Gilman, MD, David T. Martin, MD

“…Background: Chagas cardiomyopathy (CCM) is the debilitating result of a parasitic infection that causes structural and electrical abnormalities. …”
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Alternative approaches for monitoring and evaluation of lymphatic filariasis following mass drug treatment with ivermectin, diethylcarbamazine and albendazole in East New Britain P... by Krufinta Bun, Benedict Mode, Melinda Susapu, Joyceline Salo, Catherine Bjerum, Michael Payne, Daniel Tisch, Makoto Sekihara, Emanuele Giorgi, Gary J Weil, Peter U Fischer, Leanne Robinson, Moses Laman, Christopher L King

“…No children were Mf positive. However, LF infection was highly heterogeneous; 8 villages (26.7%) had a CFA prevalence >2%, and 7 villages (23.3%) had an Mf prevalence >1%. …”
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The impact of food-based incentive behaviors on oral health among Saudi children: a cross-sectional study by Yasir Dilshad Siddiqui, Saud Hamdan Almaeen, Ahmed Shawkat Hashem, Ahmed Ali Ahmed Almuntashiri, Mohammed Nadeem Baig, Abdullah Hammad Alshammari, Rital Jamal Alwaqid, Haifa Ali Almutairi, Raha Ahmed, Rakhi Issrani, Farooq Ahmad Chaudhary

“…Abstract Background Childhood dental caries is a common and significant oral health issue globally, resulting in pain, infection, and difficulties in eating and speaking. …”
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