Enhancing Mesenchymal Stromal Cell Immunomodulation for Treating Conditions Influenced by the Immune System by Bella S. Guerrouahen, Heba Sidahmed, Asma Al Sulaiti, Moza Al Khulaifi, Chiara Cugno

“…However, in 2006, a minimal set of standard criteria has been issued by the International Society of Cellular Therapy for defining derived MSCs. These include adherence to plastic in conventional culture conditions, particular phenotype, and multilineage differentiation capacity in vitro. …”
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Positively charged specificity site in cyclin B1 is essential for mitotic fidelity by Christian Heinzle, Anna Höfler, Jun Yu, Peter Heid, Nora Kremer, Rebecca Schunk, Florian Stengel, Tanja Bange, Andreas Boland, Thomas U. Mayer

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Construction of functional tissue-engineered microvasculatures using circulating fibrocytes as mural cells by Xiaolin Wang, Hong Tan, Harsha P Gunawardena, Jin Cao, Lu Dang, Hongbing Deng, Xueyong Li, Hongjun Wang, Jinqing Li, Caibin Cui, David A Gerber

“…However, a key challenge of microvascular tissue engineering is identifying a cellular source for mural cells. We showed that in vitro , circulating fibrocytes (CFs) can (1) shear and stabilize the microvasculatures formed by vascular endothelial cells (VECs) in a collagen gel, (2) form gap junctions with VECs and (3) induce basement membrane formation. …”
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Polystyrene microplastics disrupt adrenal steroid synthesis in male mice via mitochondrial dysfunction by Ying Xiong, Zhe Chen, Hanmin Xiang, Yi Liu, Yanlin Wang

“…In vitro, these occurrences coincided with an elevated rate of cell apoptosis observed in adrenocortical cells following exposure to PS-MPs. …”
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Requirement of Innate Immunity in Tumor-Bearing Mice Cured by Adoptive Immunotherapy Using Tumor-Draining Lymph Nodes by John Ammori, Khaled Hamzeh, Hallie Graor, Julian Kim

“…The purpose of this study was to determine the cellular effectors of both the adoptively transferred cells and the tumor-bearing host that participate in the antitumor response to adoptive immunotherapy using culture-activated tumor-draining lymph nodes (TDLNs). …”
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Inhibitory Effects of iPSC-MSCs and Their Extracellular Vesicles on the Onset of Sialadenitis in a Mouse Model of Sjögren’s Syndrome by Bo Hai, Taeko Shigemoto-Kuroda, Qingguo Zhao, Ryang Hwa Lee, Fei Liu

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Loss of LLGL1 Expression Correlates with Diffuse Gastric Cancer and Distant Peritoneal Metastases by Alexander Desuki, Frank Staib, Ines Gockel, Markus Moehler, Hauke Lang, Stefan Biesterfeld, Annett Maderer, Peter R. Galle, Martin R. Berger, Carl C. Schimanski

“…Loss of LLGL1 has been associated with loss of cellular adhesion and dissemination of cells from colorectal cancer and malignant melanoma. …”
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Roles of Lymphocyte Kv1.3-Channels in the Pathogenesis of Renal Diseases and Novel Therapeutic Implications of Targeting the Channels by Itsuro Kazama

“…In renal diseases, in which “chronic inflammation” or “the overstimulation of cellular immunity” is responsible for the pathogenesis, the overexpression of Kv1.3-channels in lymphocytes promotes their cellular proliferation and thus contributes to the progression of tubulointerstitial fibrosis. …”
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Implementing enclosed sterile integrated robotic platforms to improve cell-based screening for drug discovery by Alice Rockliffe, Lauren Wheeler, Kiran Lidhar, Arun Dhar, Michelle Pemberton, Richard Kasprowicz, Ceridwen Hopely, Jo Francis, Shane Marine, David Brierley, Lorna Suckling

“…At GSK, we have implemented custom integrated robotics platforms housed in bespoke biosafety enclosures to augment our capabilities in advanced cellular screening. Here we present and discuss the impact of one such system, the Cellular Automated Screening Platform (CASPer). …”
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M-Sec promotes the accumulation of intracellular HTLV-1 Gag puncta and the incorporation of Env into viral particles. by Masateru Hiyoshi, Youssef M Eltalkhawy, Randa A Abdelnaser, Akira Ono, Kazuaki Monde, Yosuke Maeda, Reem M Mahmoud, Naofumi Takahashi, Yasuyoshi Hatayama, Akihide Ryo, Satoshi Nozuma, Hiroshi Takashima, Ryuji Kubota, Shinya Suzu

“…We have demonstrated that the cellular protein M-Sec promotes the transmission of human T-cell leukemia virus type 1 (HTLV-1) in vitro and in vivo. …”
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Role of CEACAM1, ECM, and Mesenchymal Stem Cells in an Orthotopic Model of Human Breast Cancer by Sridhar Samineni, Carlotta Glackin, John E. Shively

“…Carcinoembryonic antigen-related cell adhesion molecule-1 (CEACAM1) is a morphogen in an in vitro model for lumen formation and plays a similar role in breast epithelial cells implanted in humanized mammary fat pads in NOD-SCID mice. …”
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The <i>MCPH7</i> Gene Product STIL Is Essential for Dendritic Spine Formation by Tohru Matsuki, Hidenori Tabata, Masashi Ueda, Hideaki Ito, Koh-ichi Nagata, Yumi Tsuneura, Shima Eda, Kenji Kasai, Atsuo Nakayama

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Network Pharmacology Analysis and Experimental Validation to Explore the Anti-inflammatory Mechanism of Asiatic Acid on Alcoholic Steatohepatitis by Tao Jiang, Jinhong Xu, Yang Lu, Xiaojin Chen, Yongxia Li

“…In addition, in the cellular model, real-time reverse transcriptase-polymerase chain reaction (Real-Time RT-PCR) and enzyme-linked immunosorbent assay (ELISA) results showed that AA could alleviate alcohol-induced cellular inflammation, while western blot and immunofluorescence results showed that AA might alleviate alcohol-induced cellular inflammation by inhibiting the nuclear factor-κB (NF-κB) pathway. …”
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PLK3 weakens antioxidant defense and inhibits proliferation of porcine Leydig cells under oxidative stress by Chujie Chen, Jinyan He, Weixian Huang, Dong Xu, Zhaohui Li, Anqi Yang

“…Abstract Aging is characterized by cellular degeneration and impaired physiological functions, leading to a decline in male sexual desire and reproductive capacity. …”
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Challenges in observing transcription–translation for bottom-up synthetic biology by Vadim G. Bogatyr, Gijs J. L. Wuite

“…However, to achieve this goal, it is essential first to gain a profound understanding of the cellular systems used to build that cell, how to reconstitute those systems in the compartments, and how to track their function. …”
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Identification of a guanine nucleotide exchange factor for Arf3, the yeast orthologue of mammalian Arf6. by Alison K Gillingham, Sean Munro

“…One of the most well characterised of these G proteins is mammalian Arf6, a protein that participates in many cellular processes including endocytosis, actin remodelling and cell adhesion. …”
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Photophysical Properties of Fluorescent Probe Thioflavin T in Crowded Milieu by Natalia P. Rodina, Maksim I. Sulatsky, Anna I. Sulatskaya, Irina M. Kuznetsova, Vladimir N. Uversky, Konstantin K. Turoverov

“…Such crowded cellular milieu is typically simulated in vitro using concentrated solutions of inert polymers, which do not usually interact with proteins. …”
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Current Progress in the Rejuvenation of Aging Stem/Progenitor Cells for Improving the Therapeutic Effectiveness of Myocardial Repair by Gurleen Kaur, Chuanxi Cai

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Plectin, a novel regulator in migration, invasion and adhesion of ovarian cancer by Lanning Bai, Xueqian Qian, Hui Zhang, Yi Yuan, Xiaodong Cui, Min Cheng, Yangyang Han

“…Results In this study, our findings demonstrate that PLEC exerts a positive influence on the progression of OC, encompassing cellular proliferation, migration, invasion, and adhesion both in vitro and in vivo. …”
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Electrochemical impedance spectroscopy as a micropropagation monitoring tool for plants: A case study of tamarillo Solanum betaceum callus by André Caeiro, Jorge Canhoto, Paulo R.F. Rocha

“…Summary: Tamarillo is an economically important species that has been extensively studied in terms of in vitro morphogenesis and micropropagation techniques, including somatic embryogenesis. …”
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