The presence of pleural effusion is an independent prognostic factor in patients with malignant pleural mesothelioma by Haoyu Wang, Ruiyuan Yang, Dan Liu, Weimin Li

“…Future studies are needed to validate these findings, particularly concerning the effect of PE in other clinical settings, such as immunotherapy.…”
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IL-8, IL-10, TGF-β, and GCSF Levels Were Increased in Severe Persistent Allergic Asthma Patients with the Anti-IgE Treatment by Arzu D. Yalcin, Atil Bisgin, Reginald M. Gorczynski

“…Our study gives a different perspective for the SPA and anti-IgE immunotherapy efficacy at the cell cytokine-linked step.…”
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Case report: Diagnosis of impaired consciousness in a cancer patient using immune checkpoint inhibitors by Daniel Cathalifaud, Daniel Cathalifaud, Cristóbal Basáez, Tatiana Yáñez, Tatiana Yáñez

“…We present the case of a patient diagnosed with pleural mesothelioma that started combined palliative immunotherapy two months before admission. She was hospitalized for delirium with psychotic symptoms and a comprehensive neurological and etiological examination for this pathology was performed, revealing undetectable TSH levels, indicating the etiology of the condition as thyrotoxicosis in the context of autoimmune thyroiditis, secondary to treatment with ICIs. …”
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Phase I Study of Anti-CD3 x Anti-Her2 Bispecific Antibody in Metastatic Castrate Resistant Prostate Cancer Patients by Ulka Vaishampayan, Archana Thakur, Ritesh Rathore, Nicola Kouttab, Lawrence G. Lum

“…Immune evaluations of peripheral blood mononuclear cells in 2 patients before and after immunotherapy showed increases in IFN-γ EliSpot responses and Th1 serum cytokines. …”
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Multiomic machine learning on lactylation for molecular typing and prognosis of lung adenocarcinoma by Mengmeng Hua, Tao Li

“…The tumor microenvironment analysis illustrated that immune activity was notably elevated in low-risk patients, indicating they might more strongly respond to immunotherapy than high-risk patients. Further, oncoPredict analysis revealed that low-risk patients have increased sensitivity to chemotherapeutics. …”
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Modulation of gut microbiota in targeted cancer therapy: insights on the EGFR/VEGF/KRAS pathways by Li Gong, Shixue Yang, Junli Huang, Yongsheng Li

“…Research has investigated the impact of gut microbiota on the efficacy of various anticancer therapies, such as immunotherapy, chemotherapy, and radiotherapy. However, a notable gap exists in the literature regarding the relationship between gut microbiota and targeted agents. …”
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TGF‐β regulates the release of breast cancer cell‐derived extracellular vesicles and the sorting of their protein cargo by downregulating RAB27B expression by Chao Li, Agustin Enciso‐Martinez, Roman I. Koning, Mona Shahsavari, Peter ten Dijke

“…Our findings reveal the critical roles of TGF‐β and RAB27B in cancer development by regulating EV release and composition and thus provide potential targets to improve cancer immunotherapy.…”
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Preferential Th1 Cytokine Profile of Phosphoantigen-Stimulated Human Vγ9Vδ2 T Cells by Margaret R. Dunne, Bozgana A. Mangan, Laura Madrigal-Estebas, Derek G. Doherty

“…Thus, phosphoantigen-stimulated Vγ9Vδ2 T cells have potential as Th1-biasing adjuvants for immunotherapy.…”
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Automating skin cancer screening: a deep learning by Nada M. Rashad, Noha MM. Abdelnapi, Ahmed F. Seddik, M. A. Sayedelahl

“…Recent advancements in immunotherapy have revolutionized skin cancer diagnosis, but manual identification remains time-consuming. …”
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The Prediction of Necroptosis-Related lncRNAs in Prognosis and Anticancer Therapy of Colorectal Cancer by Hanyu Xiao, Qidan Pang, Yong Wang, Suhe Lai, Hong Chen

“…By analyzing the difference in the tumor microenvironment, microsatellite instability, and tumor mutation burden between the two groups, we explored the potential chemotherapy and immunotherapy drugs. Results. We screened out 9 nrlncRNAs and built a prognostic signature based on them. …”
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Mining Prognostic Biomarkers of Thyroid Cancer Patients Based on the Immune-Related Genes and Development of a Reliable Prognostic Risk Model by Hongjun Fei, Xu Han, Yanlin Wang, Shuyuan Li

“…Our study established and verified a dependable prognostic model associated with immune for THCA, both the identified IRGs and immune-related risk model were clinically significant, which is conducive to promoting individualized immunotherapy against THCA.…”
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Awardee Summary of 2023 Taiwan Oncology Society Clinical Research Award Recipient: Persistent Endeavors on Research of Digestive Cancers for Three Decades by Kun-Huei Yeh

“…Conclusion: In the future, our team will make persistent endeavors in research on digestive cancers for immunotherapy and precision medicine to further improve treatment outcomes.…”
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Use of failure mode and effect analysis to improve the monoclonal antibody drugs management process in pharmacy intravenous admixture services by Jian Cai, Min-Xian Li, Shuai Lu, Dan Shen, Wei Xie, Jian-Jun Zhu, Guo-Jun Jiang, Chun-Xiao Lu

“…Abstract Monoclonal antibodies (mAbs) constitute a new form of immunotherapy that has shown great success in long-term tumour control. …”
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Gut Microbiota Secondary Metabolites: Key Roles in GI Tract Cancers and Infectious Diseases by Eman K. E. Anwer, Muhammad Ajagbe, Moustafa Sherif, Abobaker S. Musaibah, Shuaib Mahmoud, Ali ElBanbi, Anwar Abdelnaser

“…Conversely, these same metabolites hold therapeutic promise, potentially enhancing responses to chemotherapy and immunotherapy and even directly suppressing tumor growth. …”
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Global research hotspots and trends in DNA vaccine research: A bibliometric and visualization study from 2014 to 2024 by Juan Zhang, Haiguo Zhang, Cuicui Yao, Lihua Gu, Shasha Dong, Yamei Wu, Lele Miao

“…Keywords cluster analysis distinguished four major research directions: infectious disease and immunity, viral challenge and vaccine development, optimization of DNA vaccine delivery systems, and cancer and immunotherapy research. The literature co-citation analysis revealed four major research hotspots, including DNA vaccines for Zika virus, human papillomavirus (HPV), and COVID-19, as well as safety, efficacy, and immunogenicity studies of DNA vaccines. …”
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Genetic and molecular insights in oral squamous cell carcinoma therapy - Advancing the horizon by Prathiksha Srikanthan, Suresh Malakondaiah, Iadalin Ryntathiang, Mukesh Kumar Dharmalingam Jothinathan

“…Immune cell dynamics and personalized immunotherapy are important to be understood to achieve better therapeutic results. …”
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Venlafaxine-induced serotonin syndrome causing bilateral cerebral strokes: a case report by Nils Mein, Khadija Mammadli, Felix Luessi, Timo Uphaus, Timo Uphaus

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Insights from in vivo preclinical cancer studies with histotripsy by Tejaswi Worlikar, Timothy Hall, Man Zhang, Mishal Mendiratta-Lala, Michael Green, Clifford S. Cho, Zhen Xu

“…Research is underway to combine histotripsy with immunotherapy and chemotherapy to improve therapeutic outcomes. …”
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The role of sensitization to aeroallergens and its determination in children with asthma in Ukraine by O.V. Mozyrska, Ya.V. Socolova

“…Identifying causative allergens allows for monitoring allergy triggers and determining which asthma patients will be candidates for allergen-specific immunotherapy (ASIT). Today, most children with asthma do not receive ASIT because of the lack of awareness at the primary care level, a lack of testing for aeroallergen sensitization, and financial inaccessibility of examination and treatment in Ukraine. …”
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Metabolic Reprograming of Macrophages: A New Direction in Traditional Chinese Medicine for Treating Liver Failure by Junli Zhang, Na Li, Xiaoyu Hu

“…Targeting macrophages through immunotherapy holds significant promise as a therapeutic strategy. …”
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