PD-L1/TLR7 dual-targeting nanobody-drug conjugate mediates potent tumor regression via elevating tumor immunogenicity in a host-expressed PD-L1 bias-dependent way by Wei Huang, Ji Zhou, Jia Li, Yakun Wan, Chao Hu, Meng Liu, Pan Xu, Feng Tang, Jianhua Sun, Xiaolu Yu, Yiru Long, Binfan Chen, Yongliang Tong, Mengwen Shan, Xiaomin Jia, Henglei Lu, Runqiu Chen, Jin Ren, Guangyi Jin, Likun Gong

“…Journal for ImmunoTherapy of Cancer…”
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Inflamed immune phenotype predicts favorable clinical outcomes of immune checkpoint inhibitor therapy across multiple cancer types by Jeanne Shen, Sergio Pereira, Chan-Young Ock, Yung-Jue Bang, Seulki Kim, Sehhoon Park, Se-Hoon Lee, George A Fisher, Young Kwang Chae, Yoon-La Choi, Jin-Haeng Chung, Tony S K Mok, Leeseul Kim, Jun-Eul Hwang, Gahee Park, Sanghoon Song, Seunghwan Shin, Yoojoo Lim, Wonkyung Jung, Heon Song, Hyojin Kim, Taebum Lee, Sukjun Kim, Chang Ho Ahn, Seokhwi Kim, Ben W Dulken, Stephanie Bogdan, Maggie Huang, Chiyoon Oum, Siraj M. Ali

“…Journal for ImmunoTherapy of Cancer…”
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Anti-PD-1 amplifies costimulation in melanoma-infiltrating Th1-like Foxp3+ regulatory T cells to alleviate local immunosuppression by Fernando Alvarez, Fan Huang, Sonia V Del Rincon, Mikhaël Attias, Tho-Alfakar Al-Aubodah, Roman Istomine, Paige McCallum, Abrahim Sleiman, Tamiko Nishimura, Yasser Riazalhosseini, Ciriaco A Piccirillo

“…Journal for ImmunoTherapy of Cancer…”
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Glut3 overexpression improves environmental glucose uptake and antitumor efficacy of CAR-T cells in solid tumors by Hui Wang, Yi Zhang, Feng Li, Shasha Liu, Shumin Wang, Wenhao Hu, Yue Liang, Chunyi Shen, Yuyu Zhao

“…Journal for ImmunoTherapy of Cancer…”
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Immune dysfunction revealed by digital spatial profiling of immuno-oncology markers in progressive stages of renal cell carcinoma and in brain metastases by Wei Wei, Michael Hurwitz, Sabina Signoretti, Lucia Jilaveanu, Toni K Choueiri, David L Rimm, Adebowale Adeniran, Sandra Martínez, Harriet M Kluger, David A Schoenfeld, Myrto Moutafi, Dijana Djureinovic, Ross D Merkin, David A Braun, Fabio Parisi

“…Journal for ImmunoTherapy of Cancer…”
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CD47/SIRPα axis: bridging innate and adaptive immunity by Sjoerd H van der Burg, Anneloes van Duijn, Ferenc A Scheeren

“…Journal for ImmunoTherapy of Cancer…”
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Intratumoral oncolytic virus OH2 injection in patients with locally advanced or metastatic sarcoma: a phase 1/2 trial by Lu Zhang, Shu Li, Jing Huang, Yan Wu, Liang Han, Tian Gao, Qingxia Fan, Suxia Luo, Binlei Liu, Lixin Zhou, Xinyu Wang, Ling Jia, Jianhua Shi, Zhichao Tan, Zhengfu Fan, Sijuan Ding, Chujie Bai, Ruifeng Xue, Jiayong Liu

“…Journal for ImmunoTherapy of Cancer…”
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Durvalumab and tremelimumab in combination with metronomic oral vinorelbine for recurrent advanced cervical cancer: an open-label phase I/II study by Pernelle Lavaud, Esma Saada-Bouzid, Renaud Sabatier, Olivia Le Saux, Thibault de la Motte Rouge, Anthony Gonçalves, Elodie Coquan, Jean-Sébastien Frenel, Marta Jiménez, Alice Hervieu, Laurent Mathiot, François Legrand, Claire Cropet, Edith Borcoman, Emmanuelle Charafe

“…Journal for ImmunoTherapy of Cancer…”
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High peripheral T cell diversity is associated with lower risk of toxicity and superior response to dual immune checkpoint inhibitor therapy in patients with metastatic NSCLC by Alexandre Reuben, Mehmet Altan, Latasha Little, Jianjun Zhang, Ajay Sheshadri, Hai T Tran, Mara B Antonoff, Stephen G Swisher, John V Heymach, Saumil Gandhi, Natalie Vokes, Ziyi Li, Ruoxing Li, Runzhe Chen, Joshua Baguley, Jefferson Sinson, Greg Lizee

“…Journal for ImmunoTherapy of Cancer…”
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Diabetes insipidus and Guillain-Barré-like syndrome following CAR-T cell therapy: a case report by Christian Koch, Patrick Roth, Juliane Fleischer, Todor Popov, Karl Frontzek, Bettina Schreiner, Markus G. Manz, Simone Unseld, Antonia M. S. Müller, Norman F. Russkamp

“…Journal for ImmunoTherapy of Cancer…”
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TCR-engaging scaffolds selectively expand antigen-specific T-cells with a favorable phenotype for adoptive cell therapy by Marco Donia, Özcan Met, Julie Westerlin Kjeldsen, Sine Reker Hadrup, Inge Marie Svane, Arianna Draghi, Anders Handrup Kverneland, Christina Heeke, Siri Amanda Tvingsholm, Marcus Svensson Frej, Vibeke Mindahl Rafa, Ulla Kring Hansen, Maria Ormhøj, Alexander Tyron, Agnete W P Jensen, Mohammad Kadivar, Amalie Kai Bentzen, Kamilla K Munk, Gitte N Aasbjerg, Jeppe S H Ternander, Tripti Tamhane, Christian Schmess, Samuel A. Funt, Søren Nyboe Jakobsen

“…Journal for ImmunoTherapy of Cancer…”
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Association of age, race, and ethnicity with access, response, and toxicities from CAR-T therapy in children and adults with B-cell malignancies: a review by Marco Ruella, Guido Ghilardi, Zainul S. Hasanali, Sandra P. Susanibar-Adaniya, Lena E. Winestone, Alfred L. Garfall

“…Journal for ImmunoTherapy of Cancer…”
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Targeting Siglec-E facilitates tumor vaccine-induced antitumor immunity in renal carcinoma by Yuchen Zhang, Junnian Zheng, Li Sun, Guangya Zhao, Yingxiang Shao, Bowen Lu, Jiage Ding, Yanyan Zheng, Renjin Chen, Dafei Chai, Jiawei Wang, Zichun Zhang, Xiaohui Xie

“…Journal for ImmunoTherapy of Cancer…”
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Teaching an old dog new tricks: re-engineering IL-2 for immuno-oncology applications by Mario Sznol, Naiyer Rizvi

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Knowledge, attitude, practices, and associated factors toward cervical cancer among female health sciences students of Addis Ababa University, Addis Ababa, Ethiopia by Sisay Endale, Kalkidan Delelegn, Zenebe Negash

“…Therapeutic Advances in Vaccines and Immunotherapy…”
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New prognostic model in patients with advanced urothelial carcinoma treated with second-line immune checkpoint inhibitors by Ernest Choy, Yohann Loriot, Fabio Calabrò, Cora N Sternberg, Guillermo De Velasco, Daniel Castellano, Roubini Zakopoulou, Aristotelis Bamias, Nicholas James, Axel Merseburger, F Lopez-Rios, Mario Kramer, Kimon Tzannis

“…Journal for ImmunoTherapy of Cancer…”
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Generation of novel oncolytic vaccinia virus with improved intravenous efficacy through protection against complement-mediated lysis and evasion of neutralization by vaccinia virus... by Dong-Sup Lee, Mi-Ju Park, Namhee Lee, Yun-Hui Jeon, Jiyoon Yoo, Suk-kyung Shin, Songyi Lee, Byung-Jin Jung, Yun-Kyoung Hong, Keunhee Oh

“…Journal for ImmunoTherapy of Cancer…”
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Human blood cell transcriptomics unveils dynamic systemic immune modulation along colorectal cancer progression by Pedro J Romero, Mauro Delorenzi, Amaia Martínez-Usatorre, Laura Ciarloni, Noushin Hadadi, Eric Durandau, Sylvain Monnier-Benoit, Paolo Angelino, Victoria Wosika, Alessandra Jordano Conforte, Sara S Fonseca Costa, Hector Fabio Satizabal, Jérémie Despraz, Andres Perez-Uribe, Stephan Morgenthaler, Brian Hashemi, Sahar Hosseinian-Ehrensberger

“…Journal for ImmunoTherapy of Cancer…”
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Soluble and cell-based markers of immune checkpoint inhibitor-associated nephritis by Sandra M Herrmann, Riley Fadden, Ryan J Sullivan, Kerry L Reynolds, Harish Seethapathy, Meghan E Sise, Shruti Gupta, Alexandra-Chloe Villani, Qiyu Wang, Daiana Moreno, Destiny Harden, R Neal Smith, Ivy A Rosales, Robert B Colvin, Sarah Chute, Lynn D Cornell, Nancy J Yang, Sara Barmettler, Sophia Wells, Jocelyn Farmer

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Clinical significance of plasma-free amino acids and tryptophan metabolites in patients with non-small cell lung cancer receiving PD-1 inhibitor: a pilot cohort study for developin... by Akihiko Kawahara, Tetsuro Sasada, Koichi Azuma, Hidenobu Ishii, Norikazu Matsuo, Takaaki Tokito, Tomoaki Hoshino, Yohei Miyagi, Huihui Xiang, Tomoyuki Tagami, Rika Kasajima, Yumiko Kato, Sachise Karakawa, Shinya Kikuchi, Akira Imaizumi, Kenta Murotani

“…Journal for ImmunoTherapy of Cancer…”
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