Identification of Selection Signatures Related to Johne\'s Disease in Iranian Holstein Cows using Genomic Data by Fateme Navoshki, Hossein Moradi shahr babak, Ali Sadeghi Sefid Mazgi, johann soelkner

“…Most of the genes identified in this study were related to immunity, cancer, bacterial invasion of cells, cell aging, cell response, growth, and cell adhesion, which are among the important biological traits and characteristics of living organisms. …”
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Threat of COVID-19 impacting on a quaternary healthcare service: a retrospective cohort study of administrative data by Deborah A Williamson, Mark Putland, Bruce CV Campbell, Digsu N Koye, Timothy N Fazio, Benjamin Smith, Leeanne Grigg, Douglas Johnson, Jonathan C Knott, Jo Douglass, Elissa McNamara, Leanne Saxon, Katherine Bond, Martin J Dutch, David J Read, Benjamin NJ Thomson, Steven YC Tong

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The molecular receptor NKBB enhances the persistence and anti-hepatocellular carcinoma activity of GPC3 CAR-T cells by Minghao Sui, Tiantian Liu, Xuanli Song, Ji Li, Han Ding, Yuqian Liu, Xinyu Wang, Huimin Liu, Yuchan Xue, Jianni Qi, Miao Zhang, Songbo Zhao, Qiang Zhu

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Lutetium-177 labeled iPD-L1 as a novel immunomodulator for cancer-targeted radiotherapy by Myrna Luna-Gutiérrez, Erika Azorín-Vega, Rigoberto Oros-Pantoja, Blanca Ocampo-García, Pedro Cruz-Nova, Nallely Jiménez-Mancilla, Gerardo Bravo-Villegas, Clara Santos-Cuevas, Laura Meléndez-Alafort, Guillermina Ferro-Flores

“…PD-L1 is responsible for inhibiting the immune checkpoint protein PD-1 expressed by regulatory T cells. …”
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EBV CHRONIC INFECTIONS by Eligio Pizzigallo, Delia Racciatti, Valeria Gorgoretti

“…The mechanisms of EBV latency have been carefully examined both because they represent the virus strategy to elude the response of the immune system of the host, and because they are correlated with those oncologic conditions associated to the viral persistence, particularly lymphomas and lymphoproliferative disorders. …”
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Characteristics of the hepatotropic activity of cell-free cryopreserved biological agents in the model of autoimmune hepatitis by F.V. Hladkykh, Т.І. Liadova

“…Autoimmune hepatitis (AIH) is a severe acute or chronic progressive and relapsing immune-mediated inflammatory liver disease with dynamic and heterogeneous manifestations, potentially leading to cirrhosis and liver failure. …”
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EULAR standardised training model for ultrasound-guided, minimally invasive synovial tissue biopsy procedures in large and small joints by Annamaria Iagnocco, Andrew Filer, Gabriel Herrero-Beaumont, Peter Balint, Ingrid Moller, Esperanza Naredo, Lene Terslev, Alessandra Bruns, Aurélie Najm, Ana Rodriguez, Raquel Largo, Stefano Alivernini, Jesús Garrido, Maria Antonietta D’Agostino, Jacqueline Uson, Juhani Koski, Maribel Miguel, Carlos Guillén-Astete, David A. Bong, George A.W. Bruyn, Carlos Acebes

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Corrigendum: Longitudinal mitochondrial bioenergetic signatures of blood monocytes and lymphocytes improve during treatment of drug-susceptible pulmonary tuberculosis patients by Bridgette M. Cumming, Kelvin W. Addicott, Fernanda Maruri, Fernanda Maruri, Vanessa Pillay, Rukaya Asmal, Sashen Moodley, Beatriz Barreto-Durate, Beatriz Barreto-Durate, Mariana Araújo-Pereira, Mariana Araújo-Pereira, Matilda Mazibuko, Zoey Mhlane, Nikiwe Mbatha, Khadija Khan, Senamile Makhari, Farina Karim, Lauren Peetluk, Alexander S. Pym, Mahomed Yunus S. Moosa, Yuri F. van der Heijden, Yuri F. van der Heijden, Yuri F. van der Heijden, Timothy S. Sterling, Timothy S. Sterling, Bruno B. Andrade, Bruno B. Andrade, Alasdair Leslie, Alasdair Leslie, Alasdair Leslie, Adrie J. C. Steyn, Adrie J. C. Steyn, Adrie J. C. Steyn

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Effect of high-fat diet on adipose tissues structure and inflammatory characteristics during pregnancy in mice by LU Xingyu, XU Yidan, LIU Yiqin, ZHANG Qianren, DONG Yan

“…Conclusion·A high-fat diet can induce the changes of adipocyte structure and immune cell ratio, and elevate inflammation levels in adipose tissues before and during pregnancy, which also impacts the adipose structure in offspring. …”
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Probiotic Supplementation Alleviates Corticosterone-Induced Fatty Liver Disease by Regulating Hepatic Lipogenesis and Increasing Gut Microbiota Diversity in Broilers by Yuyan Feng, Wenqing Mei, Qu Chen, Xiaojing Chen, Yingdong Ni, Mingming Lei, Jie Liu

“…The results showed that probiotic administration significantly prevented CORT-induced body weight loss (<i>p</i> < 0.05) but did not alleviate the weight loss of immune organs caused by CORT. Compared to CON, the broilers in the CORT group exhibited a significant increase in triglyceride (TG) levels in plasma and liver (<i>p</i> < 0.01), as well as severe hepatocytic steatosis and hepatocellular ballooning, which was accompanied by the upregulation of hepatic lipogenesis gene expression. …”
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Non‐alcoholic fatty liver disease and heart failure: A comprehensive bioinformatics and Mendelian randomization analysis by Yayun Zhang, Lu Feng, Xin Guan, Zixiong Zhu, Yubin He, Xuewen Li

“…The top 10 hub genes (CD163, VSIG4, CXCL10, FCER1G, FPR1, C1QB, CCR1, C1orf162, MRC1 and CD38) were significantly enriched in immune response, calcium ion concentration regulation and positive regulation of monocyte chemotaxis. …”
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Research Progress on the Impact of Amino Acids on Muscle Quality in Aquatic Animals by Wuxiao ZHANG, Qingqing JIANG, Silei XIA, Hongyan TIAN, Fei LIU, Wenping YANG, Yebing YU, Zhigang YANG, Zhiqiang XU, Yongzhi ZHU, Aimin WANG

“…However, intensive and high-density aquaculture causes the deterioration of water environmental conditions, the increase of anti-nutrient factors and nutritional imbalance caused by the replacement of animal protein with plant protein in feed, and changes in the growth, immunity, and digestive ability of aquatic animals caused by changes in feed nutrients, traditional processing methods, and transportation stress. …”
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Investigation of Nutritional Factors and Malnutrition Risk Prediction Model in Hospitalized Patients with Systemic Lupus Erythematosus in China by Xia L, Yang F, Hayashi N, Ma Y, Yan B, Du Y, Chen S, Xia Y, Feng F, Ma Z

“…Luke’s International University, Tokyo, Japan; 3Department of Labor Delivery Recovery Postpartum, People’s Hospital of Zhengzhou, Zhengzhou, Henan, People’s Republic of China; 4Ningxia Medical University, Yinchuan, Ningxia, People’s Republic of China; 5Department of Clinical Nutrition, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, People’s Republic of China; 6Department of Rheumatology and Immunology, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Lijuan Xia, Department of Radiotherapy, General Hospital of Ningxia Medical University, 804 Shengli South Street, Xingqing District, Yinchuan City, Ningxia, 750004, People’s Republic of China, Email 24DN009@slcn.ac.jp; 974286683@qq.com, Fang Feng, Email 13995409352@163.comIntroduction: Nutritional status is a critical indicator of overall health and immune function, significantly influencing treatment outcomes. …”
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Regioselective Synthesis of Potential Non-Quinonoid Prodrugs of Plasmodione: Antiparasitic Properties Against Two Hemoglobin-Feeding Parasites and Drug Metabolism Studies by Elena Cesar-Rodo, Baptiste Dupouy, Cécile Häberli, Jean-Marc Strub, David L. Williams, Pascal Mäser, Matthias Rottmann, Jennifer Keiser, Don Antoine Lanfranchi, Elisabeth Davioud-Charvet

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Prevalence of potential drug‒drug interactions and associated factors among elderly patients in Ethiopia: a systematic review and meta-analysis by Tekletsadik Tekleslassie Alemayehu, Yilkal Abebaw Wassie, Abaynesh Fentahun Bekalu, Addisu Afrassa Tegegne, Wondim Ayenew, Gebresilassie Tadesse, Demis Getachew, Abebaw Setegn Yazie, Bisrat Birke Teketelew, Mekonnen Derese Mekete, Setegn Fentahun, Tesfaye Birhanu Abebe, Tefera Minwagaw, Gebremariam Wulie Geremew

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Rapid tumor vaccine using Toll-like receptor-activated ovarian cancer ascites monocytes by George Coukos, Andrea Facciabene, Lana E Kandalaft, Christopher Neal, Dallas Flies, Justine Michaux, HuiSong Pak, Michal Bassani-Sternberg, Sarah F Adams, Sylvie Rusakiewicz, Georgia A McCann, Alizée J Grimm, Cheryl L-L Chiang, Ananda Mookerjee, Stephanie Jean, Florian Huber, Denarda Dangaj, Phyllis A Gimotty

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Cardiovascular risk factors and COVID-19 outcomes in hospitalised patients: a prospective cohort study by Martijn Beudel, Auke C Reidinga, Bert-Jan H van den Born, Liffert Vogt, Tom Dormans, Suat Simsek, Didier Collard, Nick S Nurmohamed, Yannick Kaiser, Laurens F Reeskamp, Hazra Moeniralam, Renee Douma, Annet Eerens, Paul W G Elbers, Erik S G Stroes

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Approaches to modulate buffalo gut microbiome for efficient feed utilization and reduced environmental pollution by Vijit Dey, Puran C. Lailer, Tirtha K. Datta

“…A composite feed additive formulated to reduce the methanogenic archaeal population without affecting fibrolytic rumen microbes has been demonstrated to increase milk production, antioxidant status, and immunity with abatement of enteric methane production in Murrah buffaloes. …”
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Genomic surveillance and evolutionary dynamics of influenza a virus in Sri Lanka by Tibutius Thanesh Pramanayagam Jayadas, Chandima Jeewandara, Bhagya Senadheera, Heshan Kuruppu, Rivindu Wickramanayake, Padukkage Harshani Chathurangika, Nushara Senatilleke, Navanjana Warnakulasuriya, Farha Bary, Ananda Wijewickrama, Suranga Manilgama, Manouri Gamage, Nilanka Perera, Graham S. Ogg, Gathsaurie Neelika Malavige

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Serological responses to SARS-CoV-2 following non-hospitalised infection: clinical and ethnodemographic features associated with the magnitude of the antibody response by Saly Al-Taei, Sian E Faustini, Marisol Perez-Toledo, Sian Jossi, Joel D Allen, Claire Backhouse, Daniel Ebanks, Beena Emmanuel, Mark Garvey, Golaleh McGinnell, Yasunori Watanabe, Max Crispin, David C Wraith, Adam F Cunningham, Mark T Drayson, Alex G Richter, Adrian M Shields, Lynsey A Dunbar, Aduragbemi A Faniyi, Annabel Grinbergs, Joanne O'Neill

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