The Potential Diagnostic Value of Immune-Related Genes in Interstitial Fibrosis and Tubular Atrophy after Kidney Transplantation by Bin Yang, Dike Shi, Yahong Chen, Yi Zhu

“…The results of ingenuity pathway analysis (IPA) also indicated that DEGs were involved in the immune system and kidney disease-related pathways. Finally, we found multiple miRNAs that could regulate diagnostic genes from the ceRNA network. …”
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Assessment of Some Biochemical Parameters in Iraqi Women with Recurrent Miscarriage by Ruqaya K. Abbas, Amani M. Jasim, Qater Al-nada A. Al-Ibady

“…There are a number of things that can cause a miscarriage, such as inflammatory and immune system diseases. This study aims to compare the levels of calcium, Zinc, lipid peroxidation (Malondialdehyde), and superoxide dismutase (SOD) in the serum of women who have experienced a miscarriage with those of women who are pregnant and healthy. …”
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Therapeutic Implications of a Polymethoxylated Flavone, Tangeretin, in the Management of Cancer via Modulation of Different Molecular Pathways by El-Shaimaa A. Arafa, Noura T. Shurrab, Manal A. Buabeid

“…Furthermore, tangeretin works through mitigating levels of inflammatory mediators in the immune system. Using tangeretin in combination with clinically applied anticancer drugs could be a good strategy for increasing the efficiency of these agents and protecting noncancerous cells from damage caused by chemotherapy. …”
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Ectopic Oral Tonsillar Tissue: A Case Series with Bilateral and Solitary Presentations and a Review of the Literature by Masashi Kimura, Toru Nagao, Terumi Saito, Saman Warnakulasuriya, Hiroyuki Ohto, Akihito Takahashi, Kanji Komaki, Yoshiyuki Naganawa

“…In this report, we describe a rare case of bilateral symmetric ectopic oral tonsillar tissue located at the ventral surface of the tongue along with two solitary cases arising from the floor of the mouth. The role of immune system and its aberrant response leading to ectopic deposits desires further studies. …”
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Effects of natural products on macrophage immunometabolism: A new frontier in the treatment of metabolic diseases by Jiani Li, Chen Guo, Xiaofei Yang, Weinan Xie, Wenjing Mi, Chenglong Hua, Cheng Tang, Han Wang

“…This review aims to elucidate the metabolic regulation of the immune system, analyze metabolic alterations in macrophage associated with metabolic diseases, and summarize the beneficial roles of natural products in immunometabolism, providing novel insights for the prevention and therapeutic management of metabolic diseases.…”
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Effect of attenueted parapoxvirus ovis on levels of some serum cytokines and antibody response in sheep by Kamil Atlı, Atilla Şimşek

“…<p> <b>Conclusion:</b> It was concluded that the vaccines against ORFV infection considered to be used in the future should be applied after the effects on the immune system have been clearly demonstrated.…”
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Potential and development of cellular vesicle vaccines in cancer immunotherapy by Wenxi Zhao, Xianjun Li, Jialu Guan, Shuai Yan, Lizhi Teng, Xitong Sun, Yuhan Dong, Hongyue Wang, Weiyang Tao

“…Abstract Cancer vaccines are promising as an effective means of stimulating the immune system to clear tumors as well as to establish immune surveillance. …”
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Pan-cancer analysis and single-cell analysis identifies the CENPN as a biomarker for survival prognosis and immunotherapy by Nie Zhang, Zhuoying He, Xuejin Qin, Ke Han, Zhengchun Zhu, Fei Zhong

“…We employed a comprehensive suite of web platforms and software tools for data analysis, including R, Cytoscape, an integrated repository portal for tumor-immune system interactions (TISIDB), CBio Cancer Genomics Portal (cBioPortal), Search Tool for the Retrieval of Interaction Gene/Proteins (STRING), Gene Set Cancer Analysis (GSCALite), and a cancer single-cell state atlas (CancerSEA). …”
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Asymptotic analysis of mathematical model describing a new treatment of breast cancer using AZD9496 and palbociclib by Ophir Nave, Ophir Nave

“…The mathematical model that described the interaction between the cancer cells, the treatment, and the immune system cells includes a system of nonlinear ordinary differential equations of the firs order. …”
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Vitamin D and Tinospora cordifolia modulate TLR3 and TLR4 pathways, reduce inflammation, and maintain antimicrobial peptide levels in infected mice by Jamil Ahmad Shobrun, Widyarti Sri, Setiawan Meddy, Rifa’i Muhaimin

“…The activation of Toll-Like Receptor-3 (TLR3) and Toll-Like Receptor-4 (TLR4) signalling pathways is a regular pathway for immune system activation during infection. This study aimed to investigate the effects of vitamin D (VD) and Tinospora cordifolia ethanol extract (TC) on TLR3 and TLR4 receptor protein expression, proinflammatory cytokine (IL1 and IL-6) production, and antimicrobial peptide cathelicidin (CAP) production in CD11b+ cells of mice infected with Escherichia coli. …”
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Ficolin B in Diabetic Kidney Disease in a Mouse Model of Type 1 Diabetes by Charlotte Berg Holt, Jakob Appel Østergaard, Esben Axelgaard, Gitte Krogh Nielsen, Yuichi Endo, Steffen Thiel, Troels Krarup Hansen

“…Background. The innate immune system may have adverse effects in diabetes and cardiovascular disease. …”
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Tumor Necrosis Factor Induces Developmental Stage-Dependent Structural Changes in the Immature Small Intestine by Kathryn S. Brown, Huiyu Gong, Mark R. Frey, Brock Pope, Matthew Golden, Katerina Martin, Mitchel Obey, Steven J. McElroy

“…Additionally, they suggest a mechanism which, coupled with an immature immune system, may help to explain the unique susceptibility of the immature intestine to inflammatory diseases such as NEC.…”
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Proteomic analysis of murine norovirus-infected Raw 264.7 cells reveals the induction of Ras GTPases by Sung Ho Yun, Md Arif-Ur Rahman, Soo-Bin Nam, Soo Hyeon Kim, Gyuri Kim, Kun Cho, Jong-Soon Choi

“…Consequently, the recognition of Ras-related proteins can lead to a better understanding of how noroviral infection affects the immune system of the host cell.…”
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Testing of chickens experimentally infected with A/H9N2 avian influenza virus isolates for their immune responses by O. S. Osipova, M. A. Volkova, S. V. Frolov, D. B. Andreychuk, I. A. Chvala

“…CD4⁺/CD8⁺ ratios were determined with flow cytometry for initial immune status examination and for detection of apparent immune system disorders. Quantitative analysis of peripheral blood lymphocyte subpopulations in chickens revealed changes characteristic of the immune suppression. …”
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Prebiotic emergent sources for aquaculture: Microalgae and insects by Mónica Vanessa Oviedo-Olvera, Ana Angélica Feregrino-Pérez, María Isabel Nieto-Ramírez, Marta Montserrat Tovar-Ramírez, Humberto Aguirre-Becerra, Juan Fernando García-Trejo

“…Non-digestible oligosaccharides function as growth promoters of the intestinal microbiota, improving nutrient absorption and enhancing the fish immune system. Therefore, the inclusion of new prebiotic-rich ingredients in the feed of aquatic organisms has generated interest. …”
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Interleukin-1 as a Common Denominator from Autoinflammatory to Autoimmune Disorders: Premises, Perils, and Perspectives by Giuseppe Lopalco, Luca Cantarini, Antonio Vitale, Florenzo Iannone, Maria Grazia Anelli, Laura Andreozzi, Giovanni Lapadula, Mauro Galeazzi, Donato Rigante

“…A complex web of dynamic relationships between innate and adaptive immunity is now evident for many autoinflammatory and autoimmune disorders, the first deriving from abnormal activation of innate immune system without any conventional danger triggers and the latter from self-/non-self-discrimination loss of tolerance, and systemic inflammation. …”
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Synergistic impacts of propargite exposure and deformed wing virus infection on the health of western honey bees by Chia-Yang Lin, Yu-Chun Lin, Yun-Heng Lu, Shiang-Jiuun Chen, Yu-Hsien Lin, Yao-Kuang Tseng, Yu-Tzu Lin, Yueh-Lung Wu, Rong-Nan Huang

“…These findings indicate a synergistic association between viral infection and bee sensitivity to acaricides, possibly as a result of physiological or immune system impairment. Our results also indicated that adenosine supplementation enhances the resilience of bees to environmental challenges, further supporting the energy requirement hypothesis.…”
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Deubiquitinase Ubp5 is essential for pulmonary immune evasion and hematogenous dissemination of Cryptococcus neoformans by Guizhen Wang, Yan Liu, Qianyu Li, Changhui Wang, Wei Fang

“…The dynamic interplay between pathogens and host immune system determines the outcome of fungal infections. …”
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NLRP3 Inflammasome: Activation and Regulation in Age-Related Macular Degeneration by Jiangyuan Gao, Ruozhou Tom Liu, Sijia Cao, Jing Z. Cui, Aikun Wang, Eleanor To, Joanne A. Matsubara

“…As part of the innate immune system, inflammasome activation has been identified in RPE cells and proposed to be a causal factor for RPE dysfunction and degeneration. …”
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Effect of genomic regions harboring putative lethal haplotypes on reproductive performance in closed experimental selection lines of Nellore cattle by Gustavo R. D. Rodrigues, Joslaine N. S. G. Cyrillo, Lúcio F. M. Mota, Patrícia I. Schmidt, Júlia P. S. Valente, Eduarda S. Oliveira, Lúcia G. Albuquerque, Luiz F. Brito, Maria E. Z. Mercadante

“…Gene ontology analyses of these genes revealed biological processes associated with the development of sexual traits in males and females, key functions of the immune system, energy homeostasis, and embryonic development. …”
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