Comprehensive Analysis Identifies <i>THEMIS2</i> as a Potential Prognostic and Immunological Biomarker in Glioblastoma by Jianan Chen, Qiong Wu, Anders E. Berglund, Robert J. Macaulay, Arnold B. Etame

“…Glioblastoma (GBM) is a highly aggressive brain tumor characterized by its ability to evade the immune system, hindering the efficacy of current immunotherapies. …”
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Bidirectional role of neutrophils in tumor development by Haoxin Luyang, Feng Zeng, Yan Lei, Qian He, Yanhong Zhou, Juan Xu

“…Abstract Neutrophils, traditionally considered as non-specific components of the innate immune system, have garnered considerable research interest due to their dual roles in both promoting and inhibiting tumor progression. …”
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Phylostratigraphic analysis of gene networks of human diseases by Z. S. Mustafin, S. A. Lashin, Yu. G. Matushkin

“…It was also shown that among the gene networks analyzed, the highest proportion of evolutionarily young genes was found in the networks associated with diseases of the immune system (65 %), and the highest proportion of evolutionarily ancient genes was found in the networks responsible for the formation of human dependence on substances that cause addiction to chemical compounds (88 %); gene networks responsible for the development of infectious diseases caused by parasites are signif icantly enriched for evolutionarily young genes, and gene networks responsible for the development of specif ic types of cancer are signif icantly enriched for evolutionarily ancient genes.…”
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The Effects of Meditation, Breathing Exercises, and Cold Exposure using the Wim Hof Method on the Autonomic Nervous System: A Systematic Review by Abbas Ghadimi, Sajjad Ghadimi, AmirAli Jafarnezhadgero, Ebrahim Piri

“…Objective Research has shown that exercises using the Wim Hof Method can positively affect the immune system. Therefore, this study aims to systematically review the impact of meditation, breathing exercises, and cold exposure using the Wim Hof Method on the autonomic nervous system. …”
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Identification of Crotonylation Metabolism Signature Predicting Overall Survival for Clear Cell Renal Cell Carcinoma by Jie Zheng, Yingqing Liu, Kai Wei, Jiewu Shi, Lin Li, Xuefeng Jiang, Lingsong Tao

“…Immunotherapy shows promise in treating cancer by leveraging the immune system to combat cancer cells. However, the influence of crotonylation metabolism on the prognosis and tumor environment in ccRCC patients is not fully understood. …”
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Generation of IgM+ B cell-deficient Atlantic salmon (Salmo salar) by CRISPR/Cas9-mediated IgM knockout by Mari Raudstein, Ma. Michelle D. Peñaranda, Erik Kjærner-Semb, Søren Grove, H. Craig Morton, Rolf Brudvik Edvardsen

“…Vaccines are critical for disease prevention; however, a deeper understanding of the immune system is essential to improve vaccine efficacy. …”
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Why Asplenic Patients Should Not Take Care of the Neighbour’s Dog? A Fatal Course of Capnocytophaga canimorsus Sepsis by Patrick Langguth, Lothar Leissner, Günther Zick, Arno Fischer, Christiane Stuhlmann-Laiesz, Mona Salehi Ravesh, Friederike Austein, Olav Jansen, Marcus Both

“…In patients with a compromised immune system, CC can induce a systemic infection with a fulminant course of disease. …”
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Characterization of Positive and Suspected COVID-19 Cases with Comorbidities by Yoenny Peña García, Annia Suárez Padilla, Niuva Milagro Arruebarrena Blanco

“…<strong>Background:</strong> factors associated with the severity and worse prognosis in SARS-CoV-2 infection have been described, such as age, the presence of chronic diseases such as diabetes, arterial hypertension and those that compromise the immune system. <br /><strong>Objective:</strong> to characterize positive and suspected COVID-19 cases with comorbidities in the Puerto Padre municipality between March and May 2020. …”
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Preferential Th1 Cytokine Profile of Phosphoantigen-Stimulated Human Vγ9Vδ2 T Cells by Margaret R. Dunne, Bozgana A. Mangan, Laura Madrigal-Estebas, Derek G. Doherty

“…Human Vγ9Vδ2 T cells recognise pyrophosphate-based antigens (phosphoantigens) and have multiple functions in innate and adaptive immunity, including a unique ability to activate other cells of the immune system. We used flow cytometry and ELISA to define the early cytokine profiles of Vγ9Vδ2 T cells stimulated in vitro with isopentenyl pyrophosphate (IPP) and (E)-4-hydroxy-3-methyl-but-2 enyl pyrophosphate (HMB-PP) in the absence and presence of IL-2 and IL-15. …”
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Mechanisms of bacterial-to-host interaction and their disorders at inflammatory bowel diseases by Ye. A. Poluektova, O. S. Lyashenko, A. V. Korolev, O. S. Shifrin, V. T. Ivashkin

“…Disorder of barrier function of intestine at IBD patients, in combination to prevalence of opportunistic and pathogenic microorganisms in intestinal biome, results in essential overload of innate and adaptive immune system.Conclusion. At IBD, all mechanisms providing interaction of bacterial cells with the host body are malfunc tioning to some extent, that, in combination to genetic predisposition to this disease, results in development of clinical symptoms and morphological changes.…”
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Impact of Microbiota on Irritable Bowel Syndrome Pathogenesis and Management: A Narrative Review by Mhd Bashir Almonajjed, Mahdi Wardeh, Abdallah Atlagh, Abdulrahman Ismaiel, Stefan-Lucian Popa, Flaviu Rusu, Dan L. Dumitrascu

“…This review examines the interactions between the gut microbiota, immune system, and brain, emphasizing the need for personalized therapeutic strategies. …”
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Paneth Cells: Dispensable yet Irreplaceable for the Intestinal Stem Cell NicheSummary by Michaela Quintero, Linda C. Samuelson

“…Although Paneth cells were first described as an epithelial cell component of the innate immune system due to their expression of anti-microbial peptides, they have been proposed to be niche cells due to their close proximity to intestinal stem cells and expression of niche factors. …”
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Interleukin-4 Promotes Myogenesis and Boosts Myocyte Insulin Efficacy by Yih-Hsin Chang, Jen-Ning Tsai, Tzu-Lin Chen, Kuo-Ting Ho, Hsin-Yi Cheng, Chiao-Wan Hsiao, Ming-Yuh Shiau

“…IL-4 has dual potential to act as an adjuvant therapeutic target for sarcopenia to preserve muscle mass and insulin resistance to improve insulin sensitivity, which implicates the regulation of immune system to the muscle differentiation and exercise performance.…”
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Identifying Key Biomarkers and Immune Infiltration in Female Patients with Ischemic Stroke Based on Weighted Gene Co-Expression Network Analysis by Haipeng Xu, Kelin He, Rong Hu, YanZhi Ge, Xinyun Li, Fengjia Ni, Bei Que, Yi Chen, Ruijie Ma

“…Female patients may bear a greater burden than male patients. The immune system may play an important role in the pathophysiology of females with IS. …”
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WHEAT ANTIMICROBIAL PEPTIDES by T. I. Odintsova, T. V. Korostyleva, L. L. Utkina, Ya. A. Andreev, A. A. Slavokhotova, E. A. Istomina, V. A. Pukhal’skii, T. A. Egorov

“…They are important components of the immune system in both animals and plants. AMPs differ in structure and mode of action. …”
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The Role of Genetic and Immune Factors for the Pathogenesis of Primary Sclerosing Cholangitis in Childhood by Priscila Menezes Ferri, Ana Cristina Simões e Silva, Soraya Luiza Campos Silva, Diego Junior Queiroga de Aquino, Eleonora Druve Tavares Fagundes, Débora Marques de Miranda, Alexandre Rodrigues Ferreira

“…This phenomenon contributes to abnormal immune system activation and perpetuation of the inflammatory process. …”
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The Burden of Smoking in the Health-Disease Process in People with Human Immunodeficiency Virus and AIDS by Yoenny Peña García, Luis Carlos Andraín Silva, Idalmis Sartorio Zayas, Dolys Suárez Padilla, Ana Julia Lozada Pérez

“…<br /><strong>Results:</strong> smoking in patients living with human immunodeficiency virus and AIDS had a significant statistical association with different related effects, which in order of strength of association increases the risk of deterioration of the immune system and the incidence of malignant tumours and pneumonia Pneumocystis jirovecii. …”
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Natural compounds may contribute in preventing SARS-CoV-2 infection: a narrative review by Maria Eleonora Bizzoca, Stefania Leuci, Michele Davide Mignogna, Eleonora Lo Muzio, Vito Carlo Alberto Caponio, Lorenzo Lo Muzio

“…Several studies have revealed how these substances may interfere with the viral life cycle, viral entry, replication, assembly or discharge, as well as virus-specific host targets or stimulating the host immune system, reducing oxidative stress and inflammatory response. …”
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Inflammatory Myofibroblastic Tumor: A Rarely Seen Submucosal Lesion of the Stomach by Deniz Arslan, Şeyda Gündüz, Deniz Tural, Mükremin Uysal, Ali Murat Tatlı, Cumhur İbrahim Başsorgun, Gülsüm Özlem Elpek, Hasan Şenol Coşkun, Hakan Şat Bozcuk, Burhan Savaş

“…In histopathological examination, neoplastic fusiform cells originating from a subtype of accessory immune system cells which are called fibroblastic reticulum cells are seen (Kouichi and Youichirou, 2008). …”
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Association between extracellular DNA levels, markers of inflammation and left ventricular mass index in children with chronic kidney disease by Ylva Tranæus Lindblad, Ľubomíra Tóthová, Peter Celec, Karolina Kublickiene, Peter Bárány, Milan Chromek

“…Extracellular or cell-free DNA (exDNA) originates from virtually all tissues, being released during cell death, and stimulates the innate immune system. Our study was designed as an observational, cross-sectional cohort study of children with CKD (both before and after kidney transplantation) and controls to analyze associations between exDNA, markers of inflammation, and cardiovascular health. …”
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