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681
Stunting as a Risk Factor of Soil-Transmitted Helminthiasis in Children: A Literature Review
Published 2022-01-01“…Increased inflammatory markers and intestinal microbiota dysbiosis might have increased the intensity of STH infection in stunted children that caused impairment in the immune system. While the age from 2 to 5 years along with poor hygiene and sanitation has shown to be the most common risk factors of STH infections in stunted children; currently there are no studies that show direct results of stunting as a risk factor for STH infection. …”
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682
Activated Platelets Induce an Anti-Inflammatory Response of Monocytes/Macrophages through Cross-Regulation of PGE2 and Cytokines
Published 2017-01-01“…Platelets are well known for their role in hemostasis and are also increasingly recognized for their roles in the innate immune system during inflammation and their regulation of macrophage activation. …”
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683
Hyperuricemia-induced complications: dysfunctional macrophages serve as a potential bridge
Published 2025-01-01“…Moreover, macrophages, as an indispensable component of the immune system, may serve as a promising target for addressing hyperuricemia-induced inflammation. …”
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684
Insects Induced Mango Fruit Rot: Unraveling the Culprits
Published 2024-04-01“…They act as a threat to the crops through various mechanisms of pathogenesis that compromise the immune system of the plants, such as developing any ways to attack the plants, seeking entry via open pores or exposed surface or wound, and sourcing nutrients forcefully for their growth and development. …”
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685
Mediators of Inflammation in Topical Therapy of Skin Cancers
Published 2019-01-01“…Taking into consideration that the immune system plays a very important role in the development of melanoma and non-melanoma skin cancers, which have a high prevalence in immunosuppressed patients and after prolonged ultraviolet radiation, the interest in developing novel therapies, in particular targeting the inflammation in cancer, has increased in the past years. …”
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686
<i>Trypanosoma cruzi</i>: Genomic Diversity and Structure
Published 2025-01-01“…Trans-sialidases are the most prevalent genes in the genome with a key role in the infection process, while mucins and MASPs are also significant glycosylated proteins expressed on the parasite surface, essential for its biological functions, as host–parasite interaction, host cell invasion or protection against the host immune system, in both insect and mammalian stages. Collectively, in this review, some of the most recent advances in the structure and composition of the <i>T. cruzi</i> genome are reviewed.…”
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687
Inflammasomes in neurodegenerative diseases
Published 2024-12-01“…Abstract Inflammasomes represent a crucial component of the innate immune system, which respond to threats by recognizing different molecules. …”
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688
Environmental noise exposure and autoimmune diseases: Evidence from a national cohort study
Published 2025-01-01“…Exposure to environmental noise is an inevitable factor and may pose a risk to health conditions, even potentially affecting the immune system. However, the relationship between noise exposure and autoimmune diseases has not been well explored. …”
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689
T CD3+CD8+ Lymphocytes Are More Susceptible for Apoptosis in the First Trimester of Normal Human Pregnancy
Published 2014-01-01“…Normal human pregnancy is a complex process of many immunoregulatory mechanisms which protect fetus from the activation of the maternal immune system. The aim of the study was to investigate the apoptosis of lymphocytes in peripheral blood of normal pregnant patients and healthy nonpregnant women. …”
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690
Alpha synuclein and inflammaging
Published 2025-01-01“…Thus, this review will explore a potential link between α-syn's role in the immune system, inflammaging, and PD.…”
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691
Inhibins Tune the Thymocyte Selection Process by Regulating Thymic Stromal Cell Differentiation
Published 2015-01-01“…These ligands were initially identified as hormones that regulate the hypothalamus-pituitary-gonadal axis; however, increasing evidence has demonstrated that they are key regulators in the immune system. We have previously demonstrated that Inhibins are the main Activin ligands expressed in the murine thymus and that they regulate thymocyte differentiation, promoting the DN3-DN4 transition and the selection of SP thymocytes. …”
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692
Direct Comparison of the Safety and Efficacy of Ferric Carboxymaltose versus Iron Dextran in Patients with Iron Deficiency Anemia
Published 2013-01-01“…Adverse events, including immune system disorders (0% in FCM versus 10.3% in DEX, P=0.003) and skin disorders (7.3% in FCM versus 24.4% in DEX, P=0.004), were less frequently observed in the FCM group. …”
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693
MHC Class 1 and PDL-1 Status of Primary Tumor and Lymph Node Metastatic Tumor Tissue in Gastric Cancers
Published 2019-01-01“…MHC-1 downregulation is most frequently observed in the tumor escape mechanism of cancer cells from the immune system. MHC-1 downregulation with increased PDL-1 expression of cancer cells has an important role in immune escape. …”
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694
Fipronil in sub-lethal doses leads to immuno-toxicological effects in broiler birds.
Published 2025-01-01“…So, this study was designed to evaluate the toxico-pathological effects of fipronil on the immune system of poultry birds. One hundred a-day-old chicks were purchased from a local hatchery, and standard housing conditions were provided from brooding till the end of the trail. …”
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695
Exploring Advances in Natural Plant Molecules for Allergic Rhinitis Immunomodulation in Vivo and in Vitro
Published 2025-02-01“…Furthermore, the development of AR is intricately associated with dysregulation of the immune system, yet the underlying pathogenetic mechanisms remain incompletely understood. …”
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696
Tissue‐resident memory T cells in diseases and therapeutic strategies
Published 2025-01-01“…Abstract Tissue‐resident memory T (TRM) cells are crucial components of the immune system that provide rapid, localized responses to recurrent pathogens at mucosal and epithelial barriers. …”
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697
The role of natural products targeting macrophage polarization in sepsis-induced lung injury
Published 2025-02-01“…As a key component of the innate immune system, macrophages play a vital role in SALI, in which a macrophage phenotype imbalance caused by an increase in M1 macrophages or a decrease in M2 macrophages is common. …”
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698
Evaluation of Human β-defensin-3 Diagnostic Role in a Group of Iraqi Patients with Osteoporosis
Published 2024-12-01“…Human β-defensin (HBD-3) is ananti-inflammatory peptide andcrucial part of the human innate immune system. Giving early therapeutic intervention for OP requires an early diagnosis. …”
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699
From Multimorbidity to Network Medicine in Patients with Rheumatic Diseases
Published 2024-11-01“…For instance, rheumatic diseases such as rheumatoid arthritis and systemic lupus erythematosus are not just a collection of symptoms affecting various organs but are also interconnected through underlying systemic inflammatory processes, immune system dysregulation, and genetic predispositions.…”
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700
Endoplasmic Reticulum Stress in Systemic Lupus Erythematosus and Lupus Nephritis: Potential Therapeutic Target
Published 2023-01-01“…ERS is involved in the dysfunction of B cells, macrophages, T cells, dendritic cells, neutrophils, and other immune cells, causing immune system disorders, such as SLE. In addition, ERS is also involved in renal resident cell injury and contributes to the progression of LN. …”
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