The use of hyaluronic acid fillers in patients with autoimmune endocrinopathies; in particular, women with Hashimoto’s disease – hints for aesthetic doctors by Katarzyna Bornikowska, Paweł Kubik, Wojciech Zgliczyński

“…Due to the dysfunction of the immune system in this group of patients, there is a higher risk of adverse side effects, especially those of immunological nature. …”
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The effectiveness of pocket book of healthy lifestyle for the elderly during covid-19 pandemic at the Ambon city health center by Rita Rena Pudyastuti, Kariyadi Kariyadi, Sri Eny Setyowati, Abdul Rivai Saleh Dunggio

“…During the Covid-19 pandemic that occurred from March 2020 until now, the elderly is very vulnerable to transmission of the Covid-19 virus because their immune system has begun to decrease. This study aims to determine changes in the knowledge of the elderly before and after being given the elderly healthy pocket book. …”
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Agonistic anti-NKG2D antibody structure reveals unique stoichiometry and epitope compared to natural ligands by Daniel Fallon, Ching-Shin Huang, Jingya Ma, Christopher Morgan, Zhaohui Sunny Zhou

“…Natural killer (NK) cells are effector cells of the innate immune system that distinguish between healthy and abnormal cells through activating and inhibitory receptor signaling. …”
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Histoplasmosis Presenting as Granulomatous Hepatitis: Case Report and Review of the Literature by Nancy A. Rihana, Manasa Kandula, Ana Velez, Kumud Dahal, Edward B. O’Neill

“…Histoplasmosis is most often self-limiting and goes unrecognized in the immunocompetent population but can progress to disseminated histoplasmosis in patients with an impaired immune system. Liver involvement as a part of disseminated histoplasmosis which usually originates in the lung is well known. …”
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Elucidating the Role of the T Cell Receptor Repertoire in Myelodysplastic Neoplasms and Acute Myeloid Leukemia by Georgios Petros Barakos, Vasileios Georgoulis, Epameinondas Koumpis, Eleftheria Hatzimichael

“…T cells, as integral components of the adaptive immune system, recognize diverse antigens through unique T cell receptors (TCRs). …”
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Crosstalk between Inflammation and ROCK/MLCK Signaling Pathways in Gastrointestinal Disorders with Intestinal Hyperpermeability by Lijun Du, John J. Kim, Jinhua Shen, Ning Dai

“…The barrier function of the intestine is essential for maintaining the normal homeostasis of the gut and mucosal immune system. Abnormalities in intestinal barrier function expressed by increased intestinal permeability have long been observed in various gastrointestinal disorders such as Crohn’s disease (CD), ulcerative colitis (UC), celiac disease, and irritable bowel syndrome (IBS). …”
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Advantages of breastfeeding for the mother-infant dyad by Zuzanna Chęcińska-Maciejewska, Andrzej Ciborek, Hanna Krauss, Magdalena Gibas-Dorna

“…Maternal milk contains all the necessary nutrients, strengthens the baby’s immune system, reduces the risk of cancer, allergies, and food intolerances, supports nervous system deve­lopment, and provides emotional benefits for both baby and mother. …”
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Macrophage Polarisation in the Tumour Microenvironment: Recent Research Advances and Therapeutic Potential of Different Macrophage Reprogramming by Rongqi Guo PhD, Rui Wang PhD, Weisong Zhang PhD, Yangyang Li PhD, Yihao Wang PhD, Hao Wang PhD, Xia Li PhD, Jianxiang Song PhD

“…Background Macrophages are a critical component of the innate immune system, derived from monocytes, with significant roles in anti-inflammatory and anti-tumour activities. …”
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PPARγ in Bacterial Infections: A Friend or Foe? by Aravind T. Reddy, Sowmya P. Lakshmi, Raju C. Reddy

“…We conclude that adjustment in the dosage and timing of PPARγ agonist administration, based on the competence of host antimicrobial defenses and the extent of inflammatory response and tissue injury, is critical for achieving the essential balance between pro- and anti-inflammatory effects on the immune system.…”
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Host-Parasite Relationship in Cystic Echinococcosis: An Evolving Story by Alessandra Siracusano, Federica Delunardo, Antonella Teggi, Elena Ortona

“…Despite being under constant barrage by the immune system, E. granulosus modulates antiparasite immune responses and persists in the human hosts with detectable humoral and cellular responses against the parasite. …”
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The Neurobiological Pathogenesis of Poststroke Depression by Chao Feng, Min Fang, Xue-Yuan Liu

“…Abundant studies suggested that large lesions in critical areas such as left frontal lobe and basal ganglia or accumulation of silent cerebral lesions might interrupt the pathways of monoamines or relevant pathways of mood control, thus leading to depression. Activation of immune system after stroke produces more cytokines which increase glutamate excitotoxicity, results in more cell deaths of critical areas and enlargement of infarctions, and, together with hypercortisolism induced by stress or inflammation after stroke which could decrease intracellular serotonin transporters, might be the key biochemical change of PSD. …”
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Progress on the prevention of poultry Salmonella with natural medicines by Yi Zhang, Jianglan Liu, Yinan Pan, Kai Shi, Ping Mai, Xiaokai Li, Shasha Shen

“…To address this threat, researchers have explored the use of natural products to enhance the immune system of poultry for preventing Salmonella infections. …”
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Immune Evasion Strategies of Trypanosoma cruzi by Ana Flávia Nardy, Célio Geraldo Freire-de-Lima, Alexandre Morrot

“…Microbes have evolved a diverse range of strategies to subvert the host immune system. The protozoan parasite Trypanosoma cruzi, the causative agent of Chagas disease, provides a good example of such adaptations. …”
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Natural Catalytic Antibodies in Norm, Autoimmune, Viral, and Bacterial Diseases by Georgy A. Nevinsky, Valentina N. Buneva

“…A significant increase in the relative Abz activities associated with a specific reorganization of the immune system, including changes in the differentiation and proliferation of bone marrow hematopoietic stem cells and lymphocyte proliferation in different organs. …”
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Helicobacter pylori and T Helper Cells: Mechanisms of Immune Escape and Tolerance by Tiziana Larussa, Isabella Leone, Evelina Suraci, Maria Imeneo, Francesco Luzza

“…H. pylori-driven interactions with the host immune system underlie the persistence of the infection in humans, since the bacterium is able to interfere with the activity of innate and adaptive immune cells, reducing the inflammatory response in its favour. …”
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Aptamers: A Feasible Technology in Cancer Immunotherapy by M. M. Soldevilla, H. Villanueva, F. Pastor

“…Some of them have been conjugated to other molecules to target the immune system and reduce off-target side effects. Despite the success of first-line treatments against cancer, the elevated number of relapsing cases and the tremendous side effects shown by the commonly used agents hinder conventional treatments against cancer. …”
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Transforming Growth Factor-Beta and Matrix Metalloproteinases: Functional Interactions in Tumor Stroma-Infiltrating Myeloid Cells by Jelena Krstic, Juan F. Santibanez

“…In tumorigenesis, it may act as a protumorigenic factor and have a profound impact on the regulation of the immune system response. Matrix metalloproteinases (MMPs) are a family that comprises more than 25 members, which have recently been proposed as important regulators acting in tumor stroma by regulating the response of noncellular and cellular microenvironment. …”
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The success of the tumor immunotherapy: neutrophils from bench to beside by Meng Zhu, Ru Jia, Xiaojie Zhang, Pingwei Xu

“…The present immune therapy was focused on the immune checkpoint blockade or Chimeric Antigen Receptor T-Cell Immunotherapy (CART) transfer, but how to activate the innate immune system to antitumor still lags out. Neutrophils are the most abundant circulating leukocytes in human, and heterogeneous neutrophils have been increasingly recognized as important players in tumor progression. …”
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CXCR2 Is Essential for Radiation-Induced Intestinal Injury by Initiating Neutrophil Infiltration by Jing Hu, Qian Ji, Fei Chen, Xiaoqin Gong, Chuansheng Chen, Kaijun Zhang, Ye Hua, Jinlei Wang, Rongkun Li, Xu Wang, Chunhua Dai, Ye Tian

“…Neutrophils, known as an important part of the immune system, are the most abundant leukocyte population in peripheral blood, but excessive recruitment will lead to tissue/organ injury. …”
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Alarm sings for primary immunodeficiency diagnosis. A proposal adapted to the Cienfuegos province by Yosvany Castillo Leyva, Alain Alonso Remedios, Grace de Lara García, Daynelis Pardo Martínez, Albert Vera Razumova

“…<strong>Foundation:</strong> immunodeficiency diseases are a heterogeneous group of disorders that reflect one or more components of the immune system quantitative and / or qualitative deficit. …”
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