Identification and Analysis of Key Immune- and Inflammation-Related Genes in Idiopathic Pulmonary Fibrosis by Tan Y, Qian B, Ma Q, Xiang K, Wang S

“…The content of this study is highly aligned with the journal’s advocacy of pushing the boundaries of knowledge in the immune system and is expected to bring new insights to journal readers and positively influence the future direction of research in the field.Keywords: bioinformatics, idiopathic pulmonary fibrosis, immunity, inflammation, machine learning…”
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The Association of Autoimmune Diseases with Type 1 Diabetes Mellitus in Children Depends Also by the Length of Partial Clinical Remission Phase (Honeymoon) by Gulsum Ozen, Angela Zanfardino, Santino Confetto, Alessia Piscopo, Francesca Casaburo, Nadia Tinto, Fernanda Iafusco, Gulsah Ozen, Emanuele Miraglia del Giudice, Medine Aysin Tasar, Arzu Yilmaz, Dario Iafusco

“…This may be due to a continuous and prolonged stimulation of immune system during the period of honeymoon that predispose the patient to develop other TH1 diseases. …”
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Egyptian Novel Goose Parvovirus in Immune Organs of Naturally Infected Ducks: Next-Generation Sequencing, Immunohistochemical Signals, and Comparative Analysis of Pathological Chan... by Mohamed A. Lebdah, Amal A. M. Eid, Reham M. ElBakrey, Abd Elgalil. El-Gohary, Mohamed G. Seadawy, Mohamed R. Mousa, Hagar F. Gouda, Nehal I. A. Goda, Mostafa F. El-Hosseny, Ahmed S. El-tahlawy, Rokayya Sami, Rasha A. Al-Eisa, Sarah S. Helal

“…The present study aims to better understand the nature of currently circulating GPV strains and their pathological impact on the immune system during natural outbreaks among different duck breeds in Egypt. …”
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Serum calcium and its relationship with immunoglobulin G (IgG) levels in prepartum buffaloes from the Venezuelan humid tropics by Juan Pablo Uzcátegui-Varela, Anacelmira Urbina Andueza, Janeth Caamaño Carrero

“… The immune system partially recognizes specific antigens due to the role of calcium (Ca2+) as an intracellular second messenger that regulates the humoral immune response. …”
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Extracellular vimentin is a damage-associated molecular pattern protein serving as an agonist of TLR4 in human neutrophils by Łukasz Suprewicz, Krzysztof Fiedoruk, Karol Skłodowski, Evan Hutt, Magdalena Zakrzewska, Alicja Walewska, Piotr Deptuła, Agata Lesiak, Sławomir Okła, Peter A. Galie, Alison E. Patteson, Paul A. Janmey, Robert Bucki

“…This, in turn, opens new windows of therapeutic intervention in inflammatory and immunological diseases characterized by immune system dysfunction, in which eVim and CitVim play a key role.…”
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Levels of Cytokines (IL-1β, IL-2, IL-6, IL-8, TNF-α) and Trace Elements (Zn, Cu) in Breast Milk From Mothers of Preterm and Term Infants by Bilal Ustundag, Erdal Yilmaz, Yasar Dogan, Saadet Akarsu, Halit Canatan, Ihsan Halifeoglu, Gurkan Cikim, A. Denizmen Aygun

“…Therefore, when premature infants are breastfed, necessary precautions such as supplemantary diets must be considered for possible infections and risks related with immune system deficiency.…”
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Serum Level Alteration of IL-6, IL-1β, and IFN-γ in Groups of Healthy Adults with Oxidative DNA Damage in Najaf Governorate by Dhuha S. Saleh, Hayder S. Hussain, Hasan N. Al-Haidari, Samia K. Abbas, Ayaid K. Zgair, Seenaa M. Ali

“…The present study aims to determine the effect of uranium pollution and DNA damage on the immune system function in terms of estimating the levels of serum interleukin (IL)-6, interferon-gamma (IFN-γ), and IL-1 beta (β). …”
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Chronic wounds and adaptive Pseudomonas aeruginosa: A phenotypic and genotypic characterization by Kasandra Buchholtz, Rie Jønsson, Rasmus L. Marvig, Biljana Mojsoska, Karen Angeliki Krogfelt

“…Phenotypic and genetic diversity is found in varying prevalence in clinical populations where beneficial adaptations enable the bacteria to avoid recognition and eradication by the host immune system. This study aimed to investigate the presence of Pseudomonas aeruginosa in chronic venous leg ulcers wounds over an 8-week time course. …”
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A mathematical model for treatment-resistant mutations of HIV by Helen Moore, Weiqing Gu

“…In this paper, we propose and analyze a mathematical model,in the form of a system of ordinary differential equations, governingmutated strains of human immunodeficiency virus (HIV) and theirinteractions with the immune system and treatments. Our modelincorporates two types of resistant mutations: strains that are notresponsive to protease inhibitors, and strains that are not responsiveto reverse transcriptase inhibitors. …”
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Heat Shock Proteins in Tendinopathy: Novel Molecular Regulators by Neal L. Millar, George A. C. Murrell

“…Heat shock proteins, also called damage-associated molecular patterns (DAMPs), are rapidly released following nonprogrammed cell death, are key effectors of the innate immune system, and critically restore homeostasis by promoting the reconstruction of the effected tissue. …”
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Role of Pore-Forming Toxins in Neonatal Sepsis by Andreas F.-P. Sonnen, Philipp Henneke

“…Membrane pore formation is not only a means for immediate lysis of the targeted cell but also a general mechanism that contributes to penetration of epithelial barriers and evasion of the immune system, thus creating survival niches for the pathogens. …”
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Nutritional and Pharmacological Enhancement of the Gut-Associated Lymphoid Tissue by M Keith Hanna, Kenneth A Kudsk

“…For patients who are unable to be fed by the enteral route and who require parenteral nutrition, several supplements show promise in enhancing the mucosal immune system defenses. The nutritional and pharmacological tactics that may enhance the GALT and thereby maintain mucosal immunity are examined.…”
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Gut microbiome diversity as adjuvant marker for immune function by Mahdaleny, Febriana Catur Iswanti

“…The mucosal barrier's integrity is maintained by a single layer of tightly fitted columnar epithelial, and more than 70% of the immune system components are closely associated with the GI tract. …”
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Vibrio parahaemolyticus: spread, detection and identification techniques by G. S. Skitovich, N. B. Shadrova, O. V. Pruntova

“…Rarely V. parahaemolyticus cause wound infections, infections of ears or sepsis in individuals with a compromised immune system. More than 80 serotypes were described worldwide based on antigenic properties of the somatic (0) and capsular (K) antigens. …”
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Organ-based characterization of B cells in patients with systemic lupus erythematosus by Yunan Wang, Rui Zhao, Qian Liang, Shiwen Ni, Mei Yang, Liwei Qiu, Juan Ji, Zhifeng Gu, Chen Dong

“…Dysregulation of the immune system and disruption of immune tolerance, particularly through the abnormal activation of B lymphocytes and the production of excessive autoantibodies, lead to widespread inflammation and tissue damage, resulting in multi-organ impairment. …”
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FSH and TSH in the Regulation of Bone Mass: The Pituitary/Immune/Bone Axis by Graziana Colaianni, Concetta Cuscito, Silvia Colucci

“…In addition, we will focus on the knowledge that both FSH and TSH have influence on proinflammatory and proosteoclastogenic cytokine expression, such as TNFα and IL-1, underlining the correlation of pituitary-bone axis to the immune system.…”
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Perspectives on the Role of Photodynamic Therapy in the Treatment of Pancreatic Cancer by Wei Li, Qingyong Ma, Erxi Wu

“…The antitumor effects of PDT include three main mechanisms: direct tumor cell death (necrosis, apoptosis, and autophagy), vascular destruction, and immune system activation. The present paper systematically summarizes the effects of PDT in the treatment of PC from the experimental studies to the clinical studies and discusses the mechanisms of PDT-induced PC destruction.…”
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Genetic Diversity of Toll-Like Receptors and Immunity to M. leprae Infection by Bryan E. Hart, Richard I. Tapping

“…As expected, many of the polymorphisms reside within genes that encode components of the innate and adaptive immune system. Despite the preponderance of these studies, our understanding of the mechanisms that underlie these genetic associations remains sparse. …”
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The Safety of Systemic Treatments That Can Be Used for Geriatric Psoriasis Patients: A Review by Jillian W. Wong, John Y. M. Koo

“…Patients with moderate-to-severe psoriasis are often treated with systemic immunosuppressant agents that decrease immune system function. For the elderly, these medications are often problematic due to their already immunosuppressed state and comorbidities. …”
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Regulation of Immune Function by Polyphenols by Sujuan Ding, Hongmei Jiang, Jun Fang

“…Immune dysfunction is caused by various factors, including changes in relevant immune regulators and environmental stress. Immune system imbalance leads to a variety of diseases in humans. …”
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