Hyperthermic intraperitoneal chemotherapy: Ideal and reality by Fan-He Dong, Yu-Qiang Shan, Wen-Cheng Kong, Hao-Ran Wei, Lin-Po Zhou, Ye-Bin Yang, Jing Shi, Cheng-Hao Ji, Yi-Jia Zhang

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Hyperthermic Intraperitoneal Chemotherapy with Melphalan: A Summary of Clinical and Pharmacological Data in 34 Patients by Lana Bijelic, Paul H. Sugarbaker, O. Anthony Stuart

“…Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is a treatment option for peritoneal metastases. …”
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Hyperthermic intraperitoneal chemotherapy (HIPEC) increases risk of local anesthetic systemic toxicity (LAST) by Masahiko Tsuchiya, Hiroharu Takesada, Koh Mizutani

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Morbidity and Mortality Outcomes of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy at a Single Institution in Japan by Akiyoshi Mizumoto, Emel Canbay, Masamitsu Hirano, Nobuyuki Takao, Takayuki Matsuda, Masumi Ichinose, Yutaka Yonemura

“…Even though cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are associated with a high morbidity and mortality rates, it has been reported that CRS and HIPEC improved survival of selected patients with peritoneal carcinomatosis. …”
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Single center experience with Hypotension Prediction Index (HPI) during cytoreductive surgery with Hyperthermic Intraperitoneal Chemotherapy (HIPEC) by Camilla L’Acqua, Luciano Frassanito, Shigeki Kusamura, Franco Valenza

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Changes in Hepatic Blood Flow and Liver Function during Closed Abdominal Hyperthermic Intraperitoneal Chemotherapy following Cytoreduction Surgery by Stéphanie Dupont, Eduardo R. C. Schiffer, Marion J. White, John R. A. Diaper, Marc-Joseph Licker, Philippe C. Masouyé

“…The increase in intra-abdominal pressure (IAP) during closed abdominal hyperthermic intraperitoneal chemotherapy (HIPEC) leads to major haemodynamic changes and potential organ dysfunction. …”
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Risk factors for postoperative acute kidney injury after cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy: a meta-analysis and systematic review by Dengzhuo Chen, Yongli Ma, Jinghui Li, Liang Wen, Linfeng Liu, Guosheng Zhang, Hongkai Hu, Chengzhi Huang, Xueqing Yao

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Multidisciplinary Treatment for Colorectal Peritoneal Metastases: Review of the Literature by Shaobo Mo, Guoxiang Cai

“…With the advancement of surgical techniques, hyperthermic intraperitoneal chemotherapy (HIPEC), and multidisciplinary treatment in recent years, the cognition and treatment strategies of colorectal peritoneal metastases (CPM) have changed dramatically. …”
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Benign Multicystic Peritoneal Mesothelioma: A Rare Condition in an Uncommon Gender by Muhammad S. Khurram, Hamadullah Shaikh, Uqba Khan, Jacob Edens, Warda Ibrar, Ameer Hamza, Awais Zaka, Roohi Bano, Tarik Hadid

“…We report a case series of three male patients who were diagnosed with BMPM and were treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC).…”
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Hyperthermic Intraoperative Thoracoabdominal Chemotherapy by Paul H. Sugarbaker, David Chang, O. Anthony Stuart

“…Cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is a treatment option for selected patients with pseudomyxoma peritonei (PMP) and diffuse malignant peritoneal mesothelioma (DMPM). …”
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Systemic Chemotherapy prior to Cytoreductive Surgery and HIPEC for Carcinomatosis from Appendix Cancer: Impact on Perioperative Outcomes and Short-Term Survival by Lana Bijelic, Anjali S. Kumar, O. Anthony Stuart, Paul H. Sugarbaker

“…Systemic chemotherapy administered prior to cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal mucinous adenocarcinoma of appendiceal origin (PMCA) is associated with a significant rate of histological response. …”
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Prognostic Factors of Peritoneal Metastases from Colorectal Cancer following Cytoreductive Surgery and Perioperative Chemotherapy by Yutaka Yonemura, Emel Canbay, Haruaki Ishibashi

“…Prolonged survival of patients affected by peritoneal metastasis (PM) of colorectal origin treated with complete cytoreduction followed by intraoperative hyperthermic intraperitoneal chemotherapy (HIPEC) has been reported. …”
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Incidence, risk factors, and outcomes of the transition of HIPEC-induced acute kidney injury to acute kidney disease: a retrospective study by Yunwei Lu, Ziyan Xiao, Xiujuan Zhao, Yingjiang Ye, Shu Li, Fuzheng Guo, Haiyan Xue, Fengxue Zhu

“…Background Acute kidney injury (AKI) is recognized as a common complication following cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC). Characterized by prolonged renal function impairment, acute kidney disease (AKD) is associated with a higher risk of chronic kidney disease (CKD) and mortality.Methods From January 2018 to December 2021, 158 patients undergoing CRS-HIPEC were retrospectively reviewed. …”
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INTRAOPERATIVE PHOTODYNAMIC THERAPY FOR METASTATIC PERITONEAL TUMORS by E. A. Suleimanov, V. M. Khomyakov, L. G. Serova, L. I. Moskvicheva, E. V. Filonenko, A. D. Kaprin

“…These methods of additional intraoperative specific antitumor action include intraoperative radiation therapy, hyperthermic intraperitoneal chemotherapy, intraoperative photodynamic therapy characterized by differences in difficulty of performance, mechanisms of effect on tumor and healthy tissues, efficiency. …”
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Colorectal Peritoneal Metastases: A Systematic Review of Current and Emerging Trends in Clinical and Translational Research by Foteini Stefania Koumpa, Diamantis Xylas, Maciej Konopka, Dieter Galea, Kirill Veselkov, Anthony Antoniou, Akash Mehta, Reza Mirnezami

“…In patients with CPM, radical multimodality treatment consisting of cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) has demonstrated oncological superiority over systemic chemotherapy alone. …”
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Prognosis conferred by molecular features of appendix-derived Pseudomyxoma Peritonei by Ruiqing Ma, Guojun Li, Yingjiang Ye, Lei Liang, Chong Wang, Haipeng Zhou, Pu Zhang, Lubiao An, Guanjun Shi, Qian Chen, Hongbin Xu, Zhidong Gao

“…We investigated the prognostic value for response to cytoreductive surgery (CRS) or hyperthermic intraperitoneal chemotherapy (HIPEC) and dissected potential beneficial targeted therapy utilizing genomic characteristics. …”
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Intraperitoneal paclitaxel for patients with primary malignant peritoneal mesothelioma: a phase I/II dose escalation and safety study—INTERACT MESO by Job P van Kooten, Jacobus W A Burger, Cornelis Verhoef, Joachim G J V Aerts, Eva V E Madsen, Alexandra R M Brandt-Kerkhof, Stijn L W Koolen, Ron H J Mathijssen, Michelle V Dietz, Niels A D Guchelaar

“…The only potentially curative treatment is cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC). However, the majority of patients are not eligible to undergo this treatment. …”
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