Overexpression of PLCG2 and TMEM38A inhibit tumor progression in clear cell renal cell carcinoma by Yiqiao Zhao, Liang Yang, Xiaojie Bai, Lu Du, Huan Lai, Yiyang Liu, Ping Chen, Michael E. DiSanto, Xinhua Zhang

“…In summary, we identified potential tumor suppressor factors and stratified ccRCC patients into high-risk and low-risk groups based on these factors. …”
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Linkage Mapping and Identification of Candidate Genes for Cold Tolerance in Rice (Oryza Sativa L.) at the Bud Bursting Stage by Lina Zhang, Fei Wang, Chunhui Liu, Xiaoding Ma, Di Cui, Bing Han, Longzhi Han

“…To address this, an RIL population derived from a cross between cold-tolerant and cold-sensitive rice varieties was used to identify nine QTLs linked to cold tolerance under temperatures of 4 ℃, 5 °C, and 6 ℃ using a high-density genetic map. One candidate gene, LOC_Os07g44410, was identified through gene function annotation, haplotype analysis, and qRT-PCR, with two main haplotypes (Hap1 and Hap2) showing distinct phenotypic differences. qRT-PCR analysis showed that the expression level of LOC_Os07g44410 in cold tolerant lines carrying Hap1 was significantly higher than that in cold sensitive lines carrying Hap2. …”
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External Drivers and Mesoscale Self‐Organization of Shallow Cold Pools in the Trade‐Wind Regime by Pouriya Alinaghi, A. Pier Siebesma, Fredrik Jansson, Martin Janssens, Franziska Glassmeier

“…Even without external variability, we find a strong intermittent behavior in the evolution of cold pools, governed by a complex interplay between cold pools and clouds which expresses itself in the form of shallow squall lines. These squall lines result from precipitating downdrafts, cold pool outflows and the resulting gust fronts, reinforcing parent clouds. …”
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Design and Fabrication of Orthokeratology Lens with Multi-Linear and Spherical Aberration Corrected for Myopia Control by Zhengwang Li, Ruijin Hong, Dawei Zhang

“…In the present study, a pioneering polish-free ortho-k lens was devised, featuring two reverse lines and three alignment lines, which, respectively, expedite the shaping process and enhance centration. …”
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Novel Human Induced Pluripotent Stem Cell-Based Model for Retinal Pigment Epithelial Cells to Reveal Possible Disease Mechanisms for Macular Degeneration in Pseudoxanthoma Elasticu... by Taina Viheriälä, Heidi Hongisto, Lyydia Saari, Marika Oksanen, Tanja Ilmarinen, Suvi Väärämäki, Hannu Uusitalo, Pasi Nevalainen, Heli Skottman

“…Data demonstrated that PXE-specific high-quality hiPSC lines can be established from a skin biopsy regardless of the skin-related disease phenotype and disease-specific RPE differentiation is feasible. …”
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Emodin protects against severe acute pancreatitis-associated acute lung injury by activating Nrf2/HO-1/GPX4 signal and inhibiting ferroptosis in vivo and in vitro by Gang Shen, Haiyun Wen, Huijuan Li, Xuetao Zhang, Bowen Lan, Xuanchi Dong, Peng Ge, Yalan Luo, Hailong Chen

“…Abstract Background Severe acute pancreatitis (SAP) has high morbidity, a complicated and dangerous course, and many complications, including severe pulmonary complications. …”
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Groundwater Aquifer Vulnerability Assessment using a Dar-Zarrouk Parameter in a Proposed Aboru Residential Estate, Lagos State, Nigeria by M.A. Ayuk

“…Thirteen (13) Vertical Electrical Sounding (VES) points and four (4) Dipole-Dipole resistivity profile lines were occupied on four traverse lines across the study area. …”
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Somatic embryogenesis in Larix: the state of art and perspectives by V. N. Shmakov, Yu. M. Konstantinov

“…In combination with cryopreservation, somatic embryogenesis creates the basis for the development of economically valuable lines of clones and elite genotypes. The industrial use of such genetically verified clone lines in forestry can significantly increase forest productivity compared to any conventional methods for improving tree crops that are available. …”
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Amniotic Fluid Stem Cells: Future Perspectives by Margit Rosner, Katharina Schipany, Bharanidharan Shanmugasundaram, Gert Lubec, Markus Hengstschläger

“…It is possible to generate monoclonal genomically stable AFS cell lines harboring high proliferative potential without raising ethical issues. …”
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Preparation of Lipid Nanoemulsions Incorporating Curcumin for Cancer Therapy by Songyot Anuchapreeda, Yoshinobu Fukumori, Siriporn Okonogi, Hideki Ichikawa

“…The cytotoxicity studies of curucumin solution and curcumin-loaded nanoemulsion using B16F10 and leukemic cell lines showed IC50 values ranging from 3.5 to 30.1 and 22.2 to 53.7 μM, respectively. …”
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On the issue of producing doubled haploids of table beet (<i>Beta vulgaris</i> L. var. <i>conditiva</i> Alef.) (a review) by A. M. Zaretsky, A. B. Kurina, D. V. Sokolova

“…Currently, hybrid table beet seeds make up a significant part of the seeds sold in the world due to their high synchrony, root uniformity, and the effect of heterosis. …”
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LRP1 involvement in FHIT-regulated HER2 signaling in non-small cell lung cancer by Théophile Ponchel, Emma Loeffler, Julien Ancel, Audrey Brisebarre, Nathalie Lalun, Véronique Dalstein, Anne Durlach, Gaëtan Deslée, Stéphane Dedieu, Myriam Polette, Béatrice Nawrocki-Raby

“…In a cohort of 80 NSCLC assessed by immunohistochemistry, we found a significant association between a low FHIT expression and a high pHER2 and LRP1 expression by tumor cells. Experiments of FHIT silencing showed that FHIT regulated LRP1 expression both at the mRNA and protein levels in lung cell lines. …”
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Network Planning Method for Capacitated Metro-Based Underground Logistics System by Jianjun Dong, Wanjie Hu, Shen Yan, Rui Ren, Xiaojing Zhao

“…However, the relatively high cost and risk of underground construction are serious obstacles to implementing ULS. …”
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Study on Water Absorption and Thermal Conductivity of Tunnel Insulation Materials in a Cold Region under Freeze-Thaw Conditions by Youyun Li, Huan Wang, Li Yang, Shiqiang Su

“…A thermal insulation layer is often deposited on the lining structure of tunnels in cold regions to solve the problem of frost damage. …”
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Genetic improvement of cooking time in common bean: the role of dominance by Rita Carolina de Melo, Jefferson Luís Meirelles Coimbra, Luan Tiago dos Santos Carbonari, Paulo Henrique Cerutti, Altamir Frederico Guidolin

“…ABSTRACT: This study aimed to understand how the genetic components involved in cooking time behave from the first generations of self-fertilization to the formation of lines. Two targeted crosses were used, resulting in segregating progenies at different heterozygosity levels (F2, F3, F8, and F9). …”
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Synthesis of pyranopyrazolo N-glycoside and pyrazolopyranopyrimidine C-glycoside derivatives as promising antitumor and antimicrobial agents by Hafez Hend N., El-Gazzar Abdel-Rhman B. A.

“…N-(β-D-ribofuranosyl)- and N-(β-D-xylofuranosyl)-6{[(1E)-4-chlorophenyl)-methylene] amino}4-(4-florophenyl)-3-methyl-1,4-dihydropyrano[2,3-c]-pyrazole-5-carbonitrile (6a,b) were the most active compounds against three human cancer cell lines. Also, most of the newly synthesized compounds exhibited high activity towards Gram-negative and Gram-positive bacteria. …”
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POLUDANUM’S INFLUENCE ON REPRODUCTIVE AND RESPIRATORY SYNDROME, TRANSMISSIBLE GASTROENTERITIS AND AFRICAN SWINE FEVER VIRUSES IN PRIMARY AND CONTINUOUS CELL CULTURES by D. V. Sharypova, I. Yu.  Zhukov, Ali  Mazlum, N. N. Vlasova, O. S. Puzankova, V. L. Gavrilova, A. S. Igolkin

“…As a result of performed tests it was found out that there is a link between introduction of interferon inducer and change in the PRRS, TGE, ASF virus reproduction. There was detected a high level of Poludanum’s interferon inducing activity in pig testicular primary cell cultures and spleen compared to the continuous pig embryo kidney (SPEV) and rhesus monkey kidney (MARC-145) cell lines. …”
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Current Insights into Various In Vitro Dihaploidization Techniques Used in <i>Brassica</i> Oil Crops by Pavla Bryxová, Eloy Fernández-Cusimamani, Miroslav Klíma

“…With the escalating production of <i>Brassica</i> varieties, there is growing demand for high-yielding genotypes. Doubled haploid (DH) techniques have become very popular in various Brassica breeding programs. …”
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Effect of Secondary Flows on Heat Transfer of a Gas Turbine Blade by Hesham M. El-Batsh, Sameh A. Nada, Samia Nasreldin Abdo, Abdelgalil A. El-Tayesh

“…It was found through this study that secondary flow generated by flow deflection increases heat transfer coefficient on the blade suction surface. Separation lines with high heat transfer coefficients were predicted numerically with good agreement with the experimental measurements.…”
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Experimental Study of a New Concrete Admixture and Its Function in Filling and Reinforcing Granite Fissures by Songnan Ru, Zuozhou Li, Handong Liu, Huaichang Yu, Chunlei Wei, Guangzhu Hu, Fangfang Xue, Congxian Wang, Jialiang Wang

“…A concrete admixture with water retention and superhydrophobic properties was developed according to the high tensile strength, fissure resistance, and antiseepage requirements of concrete linings. …”
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