Differential Role of Adipose Tissues in Obesity and Related Metabolic and Vascular Complications by Almudena Gómez-Hernández, Nuria Beneit, Sabela Díaz-Castroverde, Óscar Escribano

“…These new treatments may contribute not only to reduce obesity but also to prevent highly prevalent complications such as type 2 diabetes and other vascular alterations, such as hypertension or atherosclerosis.…”
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Enitociclib, a selective CDK9 inhibitor: in vitro and in vivo preclinical studies in multiple myeloma by Son Tran, Patrick Sipila, Melanie M. Frigault, Beatrix Stelte-Ludwig, Amy J. Johnson, Joseph Birkett, Raquel Izumi, Ahmed Hamdy, Ranjan Maity, Nizar J. Bahlis, Paola Neri, Aru Narendran

“…Enitociclib, a cyclin-dependent kinase 9–specific small-molecule inhibitor, was found to be highly effective in decreasing cell viability and inducing apoptosis in 4 MM cell lines. …”
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Determination of reproductive properties of virulent and vaccine classical swine fever virus strains in primary and continuous cell cultures by I. S. Kolbin, A. S. Igolkin, V. L. Gavrilova, O. S. Puzankova, Ye. V. Aronova, A. A. Yelsukova, N. N. Vlasova

“…Classical swine  fever  (CSF) is a highly dangerous porcine disease. CSF outbreaks are annually notified in several countries. …”
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Co-modulation of a circular form of PCDH11Y during neuroendocrine differentiation of prostate cancer by Giovanni Pecoraro, Ilaria Leone, Silvia Nuzzo, Santiago Negueruela, Giovanni Smaldone, Lorena Buono

“…Circular RNAs (circRNAs) have emerged as potential biomarkers due to their stability and tissue-specific expression.MethodsIn this study, we investigated the circRNA landscape during neuroendocrine transdifferentiation (NED) of PC cells using the androgen-sensitive LNCaP and androgen-insensitive DU145 cell lines. To achieve that, we applied CirComPara2 pipeline to publicly available datasets to identify the differently expressed circRNAs in the LNCaP cell lines pre- and post-transdifferentiation. …”
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A Novel PET Imaging Using 64Cu-Labeled Monoclonal Antibody against Mesothelin Commonly Expressed on Cancer Cells by Kazuko Kobayashi, Takanori Sasaki, Fumiaki Takenaka, Hiromasa Yakushiji, Yoshihiro Fujii, Yoshiro Kishi, Shoichi Kita, Lianhua Shen, Hiromi Kumon, Eiji Matsuura

“…Mesothelin (MSLN) is a 40-kDa cell differentiation-associated glycoprotein appearing with carcinogenesis and is highly expressed in many human cancers, including the majority of pancreatic adenocarcinomas, ovarian cancers, and mesotheliomas, while its expression in normal tissue is limited to mesothelial cells lining the pleura, pericardium, and peritoneum. …”
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Seahorse nanos3 plays essential roles in germ cell development in the absence of nanos2 by Lingzhen Chen, Lu Tang, Qiang Lin, Yanhong Zhang

“…Our results also showed that nanos3 was highly expressed in early meiotic germ cells, and that expression levels of nanos3 were lower in the gonad after TBT exposure. …”
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The Anti-proliferative Effect of a Novel Glutaminase Inhibitor IN-3 on Prostate Cancer Cells by Ummuhan DEMIR, Ayse Busranur CELIK

“…Methods: The cell viability upon IN-3 treatment was examined using crystal violet staining and IC50 values were calculated for cancer cell lines PC-3 and LNCaP and normal fibroblasts CCD1072sk. …”
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Differential Dynamics of ATR-Mediated Checkpoint Regulators by Daniël O. Warmerdam, Roland Kanaar, Veronique A. J. Smits

“…Although Chk1 dissociates from the chromatin upon UV damage, no change in the mobility of GFP-Chk1 was observed, supporting the notion that Chk1 is a highly dynamic protein.…”
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PMAIP1 regulates the progression of follicular thyroid carcinoma through the Wnt3/FOSL1 pathway by Haobo Wang, Fangjian Shang, Yifang Wang, Bo Pang, Bo Pang, Longfei Kang, Longfei Kang, Chuanmin Zhou, Chuanmin Zhou, Dongyun Li, Dongyun Li, Zhongxin Li, Zhongxin Li, Xia Jiang, Xia Jiang, Bo Liu, Zengren Zhao

“…MethodsThis study examined the expression level of PMAIP1 in FTC through comprehensive analysis of databases, tumor tissues, and cell lines. Following the establishment of a stably transfected plasmid in cell lines, a series of functional assays and subcutaneous xenograft experiment were conducted to investigate the role of PMAIP1 in FTC. …”
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Infants of the Spring (1932): Cutting across the Stage of Harlem’s Black Bohemia by Elisa Cecchinato

“…This article discusses how, using the metaphor of theater, and specifically the highly racially codified genre of the minstrel show, Infants of the Spring depicts male, Black, and queer identities in the modern urban landscape. …”
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On Student Access and Equity in a Reforming University: by Kwesiga, Joy Constance

“…The analysis attempts to map out the contours of student access over time, outlining the major fault lines in student diversities which include, among others, location, class and gender, as well as the state (university) response to these diversities in the context of market based reforms. …”
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Tousled-like kinase loss confers PARP inhibitor resistance in BRCA1-mutated cancers by impeding non-homologous end joining repair by Min-ah Kim, Banseok Kim, Jihyeon Jeon, Jonghyun Lee, Hyeji Jang, Minjae Baek, Sang-Uk Seo, Dongkwan Shin, Anindya Dutta, Kyung Yong Lee

“…Loss-of-function experiments were performed in multiple human cancer cell lines using siRNA-mediated knockdown or CRISPR-Cas9 gene knockout. …”
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An Overview of In Vitro Models of Alcohol‐Related Hepatocellular Carcinoma by Anoïsia Courtois, Sophie Gérard, Damien Esparteiro, Eric Nguyen‐Khac, Ingrid Marcq, Grégory Fouquet

“…Our global overview demonstrates the lack of uniformity regarding HCC cell lines, alcohol concentration, and duration of alcohol exposure among existing models. …”
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Idiopathic Granulomatous Mastitis: An Autoimmune Disease? by Fatih Altintoprak, Engin Karakece, Taner Kivilcim, Enis Dikicier, Guner Cakmak, Fehmi Celebi, Ihsan Hakkı Ciftci

“…Using the immunoblot technique, the sera of patients were assayed at dilutions of 1 : 40 and 1 : 100 for human autoantibodies of the IgG class to 15 lines of highly purified ENAs. Results. In the IIF studies for ANA, positivity was identified for four different patterns in the 1 : 40 diluted preparations, for three different patients in the 1 : 100 diluted preparations and only one pattern was identified at the 1 : 320 dilution. …”
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IMPLEMENTATION OF GENOME-WIDE SELECTION IN WHEAT by G. Charmet, E. Storlie

“…In selfing species, particularly among breeding lines, LD has been reported to range up to 1 cM or more. …”
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ZNF652-Induced circRHOT1 Promotes SMAD5 Expression to Modulate Tumorigenic Properties and Nature Killer Cell-Mediated Toxicity in Bladder Cancer via Targeting miR-3666 by Hu Ke, Jiabin Zhang, Fei Wang, Yunhe Xiong

“…Our findings suggest that circRHOT1 was highly expressed in BC tumor tissues and cell lines. …”
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Genotype × Environment Interaction Studies of Promising Teppi Coffee (Coffea arabica L.) Genotypes in Southwestern Ethiopia by Wakuma Merga, Wosene Gebreselassie, Weyessa Garedew

“…However, further researches have to target hybridization of those superior genotypes with elite lines in feature Arabica coffee breeding program.…”
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Genetic diversity of kaffir sorghum accessions from the VIR collection in kafirin-encoding loci by N. V. Alpatieva, I. N. Anisimova, M. K. Ryazanova, V. V. Vasipov, R. A. Abdullaev, O. I. Romanova, E. E. Radchenko

“…Sorghum is a universal, highly drought-resistant crop, widely cultivated throughout the world. …”
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Antitumor Effect of Demethylzeylasteral (T-96) on Triple-Negative Breast Cancer via LSD1-Mediate Epigenetic Mechanisms by Zhengjie Shen, Yongjuan Gu, Ruiyang Jiang, Heya Qian, Siyuan Li, Lixian Xu, Wenzhe Gu, Yun Zuo

“…T-96 was more susceptible to inducing the apoptosis of highly metastatic TNBC cell lines (SUM-1315). An abnormal level of histone methylation is a crucial characteristic of metastatic cancer cells. …”
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BRAF regulates circPSD3/miR-526b/RAP2A axis to hinder papillary thyroid carcinoma progression by Chuang Li, Xiaojuan Zhao, Jingge Zhao, Jing Zhao, Lemei An, Gang Wu

“…Results Data showed that circPSD3 was highly expressed in PTC patients and cell lines. CircPSD3 was found to promote cell growth and migration and inhibit apoptosis in PTC cells. …”
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