Metabolites Profiling of Manilkara mabokeensis Aubrév Bark and Investigation of Biological Activities by Xavier Worowounga, Rami Rahmani, Armel-Frederic Namkona, Sylvie Cazaux, Jean-Laurent Syssa-Magalé, Hubert Matondo, Jalloul Bouajila

“…Furthermore, cyclohexane (CYHA) and ethyl acetate induced the highest cytotoxicity against the human ovarian cancer cell lines, OVCAR (49.5%) and IGROV (48.7%), respectively. …”
Get full text

The collection of oat genetic resources held by VIR as a source of information on the history of cultivation and taxonomy of the genus, and breeding trends (a review) by I. G. Loskutov, E. V. Blinova, A. A. Gnutikov

“…., landraces, breeding lines, spring and winter forms, covered and naked genotypes, and all geographic diversity of 22 wild Avena spp. from 50 countries. …”
Get full text

Identification method of wheel-rail two-point contact state in switch area by Ping Lu, Xinyi Li, Dabin Cui, Boyang An, Wenpeng Jiang

Get full text

Analysis of Adsorption, Ion Exchange, Thermodynamic Behaviour of Some Organic Cations on Dowex 50WX4-50/H+ Cation Exchanger in Aqueous Solutions by Ehteram A. Noor, Fatma M. Al-Solmi

“…On the other hand the adsorption of both 2-OH and 3-OCH3 organic cations was found to be spontaneous and disordered with enthalpy change varies significantly with increasing organic cation concentration, suggesting dipole-dipole adsorption forces as new active sites for adsorption under conditions of relatively high concentrations. Freundlich and Dubinin-Radushkevich adsorption isotherm models reasonably describe the adsorption of the studied organic cations onto dowex 50WX4-50/H+ by segmented straight lines depending on the studied range of concentration, indicating the existence of two different sets of adsorption sites with substantial difference in energy of adsorption. …”
Get full text

GagCM9-specific CD8+ T cells expressing limited public TCR clonotypes do not suppress SIV replication in vivo. by Lara Vojnov, Mauricio A Martins, Jorge R Almeida, Zachary Ende, Eva G Rakasz, Matthew R Reynolds, Enrique J Leon, Kim L Weisgrau, Benjamin J Burwitz, Joy M Folkvord, Marlon G Veloso de Santana, Patrícia C Costa Neves, Elizabeth Connick, Pamela J Skinner, Emma Gostick, David H O'Connor, Nancy A Wilson, Myrna C Bonaldo, Ricardo Galler, David A Price, Danny C Douek, David I Watkins

“…Several lines of evidence suggest that HIV/SIV-specific CD8(+) T cells play a critical role in the control of viral replication. …”
Get full text

Тransplastomic tobacco plants producing the hydrophilic domain of the sheep pox virus coat protein L1R by D. K. Beisenov, G. E. Stanbekova, B. K. Iskakov

“…Sheep pox has a wide geographical range of distribution and poses a threat to sheep breeding worldwide, as the disease is highly contagious and is accompanied by large economic losses. …”
Get full text

Prospects of the use of wild relatives for pea (Pisum sativum L.) breeding by O. E. Kosterin

“…Aryamanesh et al. (2012) obtained five introgression lines with pea weevil resistance transferred from P. fulvum to P. sativum. …”
Get full text

Factors to affect inbred beet plants while developing material for linear selection by M. I. Fedorova, E. G. Kozar, S. A. Vetrova, V. A. Zayachkovskyi, V. A. Stepanov

“…Considering its capacities, the generative system of Beta vulgaris L. is regarded as highly productive. While inbreeding, the reproductive potential of cross-pollinated beet plants with gametophytic self-incompatibility (SI) changes significantly and is determined by a joint effect of multiple factors including the level of inbred depression. …”
Get full text

Stress resistance in barley cultivars of various agroecological origin under extreme continental climate conditions by O. A. Yusova, P. N. Nikolaev, Ya. B. Bendina, I. V. Safonova, N. I. Aniskov

“…The adaptability of the identified cultivars was confirmed by high-yielding hybrid populations produced from crossing the selected adaptable cv. …”
Get full text

MINERAL COMPOSITION OF WILD RELATIVES AND INTROGRESSIVE FORMS IN WHEAT SELECTION by T. V. Savin, A. I. Abugaliyeva, I. Cakmak, K. Kozhakhmetov

“…According to the results of topcross breeding with testers – commercial common wheat varieties Steklovidnaya 24, Almali, Zhetysu – inheritance of this trait by progenies in F2–F3 generations has been revealed in two constant lines: (Bezostaya 1×Ae. cylindrica)×T. kiharae and Zhetysu×T. kiharae.…”
Get full text

PhyIndBC: Development of a machine learning tool for screening of potential breast cancer inhibitors from phytochemicalsGitHub by Agneesh Pratim Das, Subhash M. Agarwal

“…NPs predicted as actives were further screened via ensemble virtual screening (eVS) technique against erb-b2 receptor tyrosine kinase 2 (HER2), to identify high-affinity molecules against this breast cancer drug target. …”
Get full text

DGAT1 Expression Promotes Ovarian Cancer Progression and Is Associated with Poor Prognosis by Leilei Xia, Ye Wang, Shengyun Cai, Mingjuan Xu

“…Prognosis among patients with high expression of DGAT1 was poor. After DGAT1 expression was interfered, proliferation, migration, invasion, colony forming, and tumor growth of ovarian cancer cells were inhibited. …”
Get full text

The Role of NF-κB/MIR155HG in Regulating the Stemness and Radioresistance in Breast Cancer Stem Cells by Yunbao Xu, Lu Yang, Guangming Li, Chuangzhou Rao

“…Results: Breast cancer-derived stem cells exhibited a high level of MIR155HG. Knockdown of MIR155HG reduced stemness, enhanced radiosensitivity, induced apoptosis, and arrested cells in the G1 phase. …”
Get full text

Stability of agronomic traits in interspecific hybrid potato clones in the Central Region of European Russia by M. S. Khlopyuk, N. A. Chalaya, E. V. Rogozina

“…Potato breeding is based on crosses between parental lines selected for a set of important traits: productivity, structural yield components, and resistance to abiotic and biotic stresses. …”
Get full text

Implementing the Uganda lower secondary competence-based curriculum: the equity question by Mercy Chemutai Barasa, Proscovia Namubiru Ssentamu, John Koskey Chang’ach, Susan Jepkoech Kurgat

“…Findings – Data revealed disparities among high and low socio-economic-status schools in their preparedness and capacity to implement the reform, with the consequence of divergent educational opportunities for learners in these contexts. …”
Get full text

Evaluation of Antimicrobial Activity and Cytotoxicity of an Epoxy Resin-Based Endodontic Sealer Containing Nanoparticles Amorphous Calcium Phosphate by Bilal H. Ibrahim, Hussain Al-Huwaizi

“…The cytotoxicity of the NACP incorporated AH Plus and AH Plus sealers were tested indirectly by MTT assay and directly by the multiparametric high content screening toxicology assay using fibroblast-like cells as cell lines. …”
Get full text

Design and Simulation of a Semi–Automatic Paver Block Making Machine. by Wamani, Samuel

“…These are discovered to be most appropriate for places like sidewalks, narrow streets, and road reconstructions for things like installing phone lines, installing subterranean plumbing, and so forth. …”
Get full text

Involvement of Indoleamine 2,3-Dioxygenase in Impairing Tumor-Infiltrating CD8+ T-Cell Functions in Esophageal Squamous Cell Carcinoma by Ge Zhang, Wan-Li Liu, Lin Zhang, Jun-Ye Wang, Miao-Huan Kuang, Peng Liu, Yue-Hao Lin, Shu-Qin Dai, Jun Du

“…Here, we found that the level of IDO expression in ESCC tumor specimens correlated with a reduction in the number of CD8+ TILs. Patients with high IDO expression and a low number of CD8+ TILs had significantly impaired overall survival time. …”
Get full text

Analysis of population structure and genetic diversity in a Southern African soybean collection based on single nucleotide polymorphism markers by A. Tsindi, J. S. Y. Eleblu, E. Gasura, H. Mushoriwa, P. Tongoona, E. Y. Danquah, L. Mwadzingeni, M. Zikhali, E. Ziramba, G. Mabuyaye, J. Derera

“…Low fixation index (FST) value of 0.06 was observed, indicating low genetic differences among populations. This suggests high genetic exchange among different lines due to global germplasm sharing. …”
Get full text

MODERN TREATMENT OF METASTATIC MELANOMA: FROM STANDARDS TO AN INDIVIDUALIZED APPROACH IN REAL CLINICAL PRACTICE by N. V. Zhukova, R. V. Orlova, N. Yu. Antimonik, S. I. Kutukova, N. P. Belyak, N. V. Popova, S. P. Erdniev

“…It should be noted that the proportion of patients with melanoma of late stages remains high. Until recently, only ineffective chemotherapy regimens were available for such patients. …”
Get full text