Showing 561 - 580 results of 629 for search '"Hepatocellular carcinoma"', query time: 0.06s Refine Results
  1. 561

    HBV Core Promoter Inhibition by Tubulin Polymerization Inhibitor (SRI-32007) by Raj Kalkeri, Junzhong Peng, Chunsheng Huang, Zhaohui Cai, Roger G. Ptak, Mark J. Suto

    Published 2020-01-01
    “…Approximately 257 million people chronically infected with hepatitis B virus (HBV) worldwide are at risk of developing hepatocellular carcinoma (HCC). However, despite the availability of potent nucleoside/tide inhibitors, currently there are no curative therapies for chronic HBV infections. …”
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    Article
  2. 562

    CT Imaging Findings after Stereotactic Radiotherapy for Liver Tumors by Olga R. Brook, Eavan Thornton, Mishal Mendiratta-Lala, Anand Mahadevan, Vassilious Raptopoulos, Alexander Brook, Robert Najarian, Robert Sheiman, Bettina Siewert

    Published 2015-01-01
    “…Results. 36 subjects with hepatocellular carcinoma (HCC), 25 with liver metastases, and seven with cholangiocarcinoma (CCC) were included in study. …”
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    Article
  3. 563

    Human GM-CSF/IL-3 enhance tumor immune infiltration in humanized HCC patient-derived xenografts by Kelley Weinfurtner, David Tischfield, George McClung, Jennifer Crainic, John Gordan, Jing Jiao, Emma E. Furth, Wuyan Li, Erena Tuzneen Supan, Gregory J. Nadolski, Stephen J. Hunt, David E. Kaplan, Terence P.F. Gade

    Published 2025-03-01
    “…Background & Aims: Response to immunotherapy in hepatocellular carcinoma (HCC) is suboptimal with no biomarkers to guide patient selection. …”
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    Article
  4. 564

    Novel (±)-trans-β-lactam ureas: Synthesis, in silico and in vitro biological profiling by Jurin Mladenka, Stepanić Višnja, Bojanić Krunoslav, Vadlja Denis, Kontrec Darko, Dražić Tonko, Roje Marin

    Published 2024-03-01
    “…Several of the newly synthesized trans-b-lactam ureas 4a–c, 4f, 4h, 4n, 4o, 4p, and 4s were evaluated for in vitro antiproliferative activity against liver hepatocellular carcinoma (HepG2), ovarian carcinoma (A2780), breast adenocarcinoma (MCF7) and untransformed human fibroblasts (HFF1). …”
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    Article
  5. 565

    A cell-penetrating bispecific antibody suppresses hepatitis B virus replication and secretion by Chongwei Xie, Bing Zhou, Da Yao, Xin Wang, Lihong Zhong, Chuanghua Qiu, Junfang Zhang

    Published 2025-03-01
    “…Hepatitis B virus (HBV) represents one of the major pathogenic factor that leads to chronic liver diseases and the development of hepatocellular carcinoma (HCC). The currently approved anti-HBV drugs cannot eradicate the virus or block the development of HCC. …”
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    Article
  6. 566

    Combined Liver Stiffness and Α-fetoprotein Further beyond the Sustained Virologic Response Visit as Predictors of Long-Term Liver-Related Events in Patients with Chronic Hepatitis... by Sheng-Hung Chen, Hsueh-Chou Lai, Wen-Pang Su, Jung-Ta Kao, Po-Heng Chuang, Wei-Fan Hsu, Hung-Wei Wang, Tsung-Lin Hsieh, Hung-Yao Chen, Cheng-Yuan Peng

    Published 2022-01-01
    “…Cox regression and random forest models identified the key factors, including longitudinal LS and noninvasive test results, that could predict LREs, including hepatocellular carcinoma, during prespecified follow-ups from 2010 to 2021. …”
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    Article
  7. 567

    ERG mediates the differentiation of hepatic progenitor cells towards immunosuppressive PDGFRα+ cancer-associated fibroblasts during hepatocarcinogenesis by Haoran Bai, Xinyu Zhu, Lu Gao, Shiyao Feng, Hegen Li, Xiaoqiang Gu, Jiahua Xu, Chen Zong, Xiaojuan Hou, Xue Yang, Jinghua Jiang, Qiudong Zhao, Lixin Wei, Li Zhang, Zhipeng Han, Wenting Liu, Jianxin Qian

    Published 2025-01-01
    “…Abstract Cancer-associated fibroblasts (CAFs) play important roles in the occurrence and development of hepatocellular carcinoma (HCC) and are a key component of the immunosuppressive microenvironment. …”
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    Article
  8. 568

    von Willebrand factor polymorphism (rs1063856) as a risk factor for portal vein thrombosis in chronic liver diseases by Isis Samy Bedira, Olfat M. Hendy, Moones Abdelaal, Ashraf A. Basuni, Asma Ebrahim Gaber Koshoo, Alzhraa Alkhatib, Sally S. Mandour

    Published 2025-02-01
    “…Twenty patients with PVT-linked hepatocellular carcinoma (HCC) and 20 patients with non-HCC-PVT comprised the two subgroups from the 40 PVT patients. …”
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    Article
  9. 569

    Proposed carbohydrate antigen 19-9 (CA19-9) cut-off values for the detection of pancreatic cancer in patients with poorly controlled diabetes: a real-world study by Taku Yamada, Taichi Minami, Masayo Yamada, Yasuo Terauchi

    Published 2023-11-01
    “…CA19-9 levels in two inpatients were >98.4 U/mL, most likely due to hepatocellular carcinoma and esophageal cancer. CA19-9 cut-off levels were thought to be 98.4 U/mL. …”
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    Article
  10. 570

    Causes and Clinical Profiles of Ascites at University of Gondar Hospital, Northwest Ethiopia: Institution-Based Cross-Sectional Study by Oumer Abdu Muhie

    Published 2019-01-01
    “…Five (20.8%) and 4 (16.7%) CLD patients had hepatocellular carcinoma and hepatic encephalopathy as complications, respectively. …”
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    Article
  11. 571

    METHODS OF EVALUATION OF THE FUNCTIONAL STATUS OF THE LIVER IN THE PLANNING OF ANATOMICAL RESECTIONS ABOUT PRIMARY AND METASTATIC TUMORS: CURRENT STATE OF THE PROBLEM, THEIR OWN EX... by D. V. Sidorov, N. A. Rubtsova, A. V. Leontyev, M. V. Lozhkin, L. O. Petrov, T. N. Lazutina, I. V. Pylova, P. A. Korolev, A. G. Isaeva

    Published 2015-04-01
    “…Methacetin breath test and 99mTc-technephyt hepatobiliary scintigraphy were performed prior to major resection in 53 high-risk patients, including 48 patients with hepatic metastases from colorectal cancer and 5 patients with hepatocellular carcinoma . Liver function determined with HBS was compared with methacetin breath test by unified scale.Results.  …”
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  12. 572
  13. 573

    GB Virus C Infection: Clinical Significance by Xiang Wei Meng, Masafumi Komatsu, Shigetoshi Ohshima, Kunio Nakane, Tomoo Fujii, Takashi Goto, Kazuo Yoneyama, Tomoyuki Kuramitsu, Motokazu Mukaide

    Published 1999-01-01
    “…Among patients with the non-B, non-C type of chronic disease, one of seven with cirrhosis (14%) and none with chronic hepatitis or hepatocellular carcinoma were GBV-C-positive. In chronic hepatitis C patients who had received interferon treatment, no difference was found in clinical findings, alanine aminotransferase (ALT) concentrations, histology or response to interferon between 11 patients who were GBV-C RNA-positive and 101 patients who were GBV-C RNA-negative. …”
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    Article
  14. 574

    Succinate supplementation alleviates liver cancer by inhibiting the FN1/SQLE axis-mediated cholesterol biosynthesis by Shuyuan Chang, Ayaka Tomii, Yunfei Zhou, Xun Yang, Yihong Dong, Jun Yan, Aodi Wu, Yumeng Wang, Qingxin Zhang, Hongxue Meng, Lei Yu, Wei Sun, Dabin Liu

    Published 2025-02-01
    “…However, the role of exogenous succinate in hepatocellular carcinoma (HCC) is unclear. Here, we report that the concentration of succinate in HCC tissues is lower compared to adjacent normal tissues, as determined by spatial metabolomics and quantitative metabolomics analysis. …”
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    Article
  15. 575

    Right Gastroepiploic Artery as an Alternative for Arterial Reconstruction in Living Donor Liver Transplantation by Klaus Steinbrück, Reinaldo Fernandes, Marcelo Enne, Rafael Vasconcelos, Giuliano Bento, Gustavo Stoduto, Thomas Auel, Lúcio Filgueiras Pacheco-Moreira

    Published 2014-01-01
    “…A 62-year-old woman, with cirrhosis due to hepatitis B associated with hepatocellular carcinoma, was submitted to living donor liver transplantation. …”
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    Article
  16. 576

    Artificial Intelligence and Radiomics in Cholangiocarcinoma: A Comprehensive Review by Marta Zerunian, Tiziano Polidori, Federica Palmeri, Stefano Nardacci, Antonella Del Gaudio, Benedetta Masci, Giuseppe Tremamunno, Michela Polici, Domenico De Santis, Francesco Pucciarelli, Andrea Laghi, Damiano Caruso

    Published 2025-01-01
    “…Cholangiocarcinoma (CCA) is a malignant biliary system tumor and the second most common primary hepatic neoplasm, following hepatocellular carcinoma. CCA still has an extremely high unfavorable prognosis, regardless of type and location, and complete surgical resection remains the only curative therapeutic option; however, due to the underhanded onset and rapid progression of CCA, most patients present with advanced stages at first diagnosis, with only 30 to 60% of CCA patients eligible for surgery. …”
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    Article
  17. 577

    Mechanism of triptolide regulating proliferation and apoptosis of hepatoma cells by inhibiting JAK/STAT pathway by Wang Guanglian, Zhu Zhenxin, Sun Zhengang, Yang Zhiqi

    Published 2025-01-01
    “…As an anti-liver cancer agent, TPL inhibits the proliferation of hepatocellular carcinoma cells and promotes apoptosis. The mechanism may involve inhibiting Janus kinase 1/signal transducer and activator of transcription 3 pathway and activation of apoptosis-related pathways.…”
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    Article
  18. 578

    Deciphering the heterogeneity and plasticity of the tumor microenvironment in liver cancer provides insights for prognosis by Yihao Sun, Yihao Sun, Guojuan Shi, Jian Yang, Chun-Zhong Zhou, Chuhan Peng, Yu-Hong Luo, Ying Pan, Rui-Qi Wang

    Published 2025-01-01
    “…Additionally, we found a significant connection between CAF-related genes and the prognosis of hepatocellular carcinoma patients. This research provides valuable insights into the makeup of the liver cancer tumor environment and its profound impact on patient outcomes, offering fresh perspectives for managing this challenging disease.…”
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    Article
  19. 579

    A heteropolysaccharide from Rhodiola rosea L.: preparation, purification and anti-tumor activities in H22-bearing mice by Yaru Wu, Qing Wang, Huiping Liu, Lulu Niu, Mengyu Li, Qi Jia

    Published 2023-03-01
    “…In order to explore the influence to hepatocellular carcinoma, a novel cold water-soluble polysaccharide was separated from Rhodiola rosea L. root (RLP) and then its structure and anti-cancer activities were tested. …”
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    Article
  20. 580

    The role of the interleukin family in liver fibrosis by Zixin Zhang, Zixin Zhang, Jiahui Wang, Hui Li, Qun Niu, Qun Niu, Yujing Tao, Yujing Tao, Xin Zhao, Xin Zhao, Zijian Zeng, Zijian Zeng, Haijian Dong, Haijian Dong

    Published 2025-02-01
    “…It is a critical step in the progression from chronic liver disease to cirrhosis and hepatocellular carcinoma. No chemical or biological drugs have been approved for the treatment of liver fibrosis. …”
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    Article