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441
In vitro antitumor effects of methanolic extracts of three Ganoderema mushrooms
Published 2025-01-01“…These results may encourage speculation about their possible use for the therapeutic management of hepatocellular carcinoma and breast ductal carcinoma after further investigation.…”
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442
Efficacy and safety of tenofovir and entecavir in patients with chronic hepatitis B-related cirrhosis: a systematic review and meta-analysis
Published 2025-01-01“…The meta-analysis revealed that tenofovir significantly reduced the cumulative incidence of hepatocellular carcinoma and cumulative mortality compared to entecavir in East Asian popupation, while in non East Asian populations, the two groups are roughly equivalent. …”
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443
Hepatitis B Learning Needs Assessment of Family Medicine Trainees in Canada: Results of a Nationwide Survey
Published 2011-01-01“…BACKGROUND: An estimated 350 million people worldwide have chronic hepatitis B (CHB), which is a major cause of cirrhosis and hepatocellular carcinoma.…”
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444
Liver transplantation in glycogen storage disease type III: A case‐series
Published 2025-01-01“…Hepatic fibrosis, cirrhosis and hepatocellular carcinoma (HCC) are common complications in older patients. …”
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445
Management of Solitary 1 cm to 2 cm Liver Nodules in Patients with Compensated Cirrhosis: A Decision Analysis
Published 2007-01-01“…OBJECTIVES: Current guidelines, based on expert opinion, recommend that suspected 1 cm to 2 cm hepatocellular carcinoma (HCC) detected on screening be biopsied and, if positive, treated (eg, resection or transplantation). …”
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446
Patients with Chronic Hepatitis C - Who Should Not Be Treated?
Published 2000-01-01“…The decision to treat a patient with chronic hepatitis C (CHC) is based on what is known about the risk factors for developing liver cirrhosis or hepatocellular carcinoma, as well as on conditions that contraindicate therapy or impair therapy effectiveness. …”
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447
Antiviral therapy and regression of liver fibrosis at chronic hepatitis B
Published 2010-02-01“…Decrease of severity of fibrosis (for prophylaxis of liver cirrhosis and hepatocellular carcinoma development) is one of the basic criteria of efficacy of treatment of chronic liver diseases. …”
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448
The Role of Iron in the Pathophysiology and Treatment of Chronic Hepatitis C
Published 2009-01-01“…Hepatic iron depletion has been postulated to decrease the risk of hepatocellular carcinoma in patients with cirrhosis due to chronic hepatitis C. …”
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449
Multiplex immunohistochemistry to explore the tumor immune microenvironment in HCC patients with different GPC3 expression
Published 2025-01-01“…Abstract Objectives GPC3 has been recognized as a promising target for immunotherapy in hepatocellular carcinoma (HCC). However, the GPC3-targeted immunotherapies have shown limited therapeutic efficacy. …”
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450
Burden of Disease and Cost of Chronic Hepatitis C Virus Infection in Canada
Published 2014-01-01“…BACKGROUND: Chronic infection with hepatitis C virus (HCV) is a major cause of cirrhosis, hepatocellular carcinoma and liver transplantation.…”
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451
HCC Heterogeneity: Molecular Pathogenesis and Clinical Implications
Published 2009-01-01“…Background: Hepatocellular carcinoma (HCC) poses a major challenge because of the extreme variability of the clinical outcome, which makes it difficult to properly stage the disease and thereby estimate the prognosis. …”
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452
Synthesis and Biological Evaluation of 2,4-Diaminoquinazolines as Potential Antitumor Agents
Published 2022-01-01“…Among the synthesized compounds, 4c and 5b with 4-substitution at the phenyl ring were found to have the highest inhibitory effects against breast adenocarcinoma (MCF-7), colon cancer (HCT-116), hepatocellular carcinoma (HePG-2), and human skin cancer (HFB4). …”
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453
TLRs, Alcohol, HCV, and Tumorigenesis
Published 2010-01-01“…Chronic liver damage caused by viral infection, alcohol, or obesity can result in increased risk for hepatocellular carcinoma (HCC). Ample epidemiological evidence suggests that there is a strong synergism between hepatitis C virus (HCV) and alcoholic liver diseases (ALD). …”
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454
From the Cytoplasm into the Nucleus—Hepatitis B Virus Travel and Genome Repair
Published 2025-01-01“…HBV is part of the hepadnaviridae family and one of the primary causes of acute and chronic liver infections, leading to conditions such as cirrhosis and hepatocellular carcinoma (HCC). Understanding the intracellular transport and genome repair mechanisms of HBV is crucial for developing new drugs, which—in combination with immune modulators—may contribute to potential cures. …”
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455
Research Progress on the Mechanism of Acupuncture Treatment for Nonalcoholic Fatty Liver Disease
Published 2022-01-01“…Nonalcoholic fatty liver disease (NAFLD) represents the most common chronic liver disease worldwide, ranging from simple steatosis and nonalcoholic steatohepatitis to fibrosis, cirrhosis, and hepatocellular carcinoma. Acupuncture is a long-established treatment in traditional Chinese medicine. …”
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456
NF-κB, JNK, and TLR Signaling Pathways in Hepatocarcinogenesis
Published 2010-01-01“…Hepatocellular carcinoma (HCC) is the third largest cause of cancer deaths worldwide. …”
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457
Diagnostics of hepatocellular cancer: state-of-the-art
Published 2014-10-01“…To present features of hepatocellular carcinoma (HCC) diagnostics.Key points. Factors of HCC development, principles of screening diagnostics in risk group are discussed. …”
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458
Prioritization of potential pharmacological targets for the development of anti-hepatocarcinoma drugs modulating the extrinsic apoptosis pathway: the reconstruction and analysis...
Published 2023-12-01“…Hepatocellular carcinoma (HCC) is a common severe type of liver cancer characterized by an extremely aggressive course and low survival rates. …”
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459
One-Pot Synthesis of Novel Furochromone and Oxazocine Derivatives as Promising Antitumor Agents with Their Molecular Docking Studies
Published 2020-01-01“…The obtained derivatives of novel furochromone and oxazocine derivatives were evaluated as promising antitumor agents against panel of two human cell lines, hepatocellular carcinoma (HEPG2) and breast carcinoma (MCF7). …”
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460
Surviving Emphysematous Gastritis after Hepatectomy
Published 2013-01-01“…We are reporting a middle-aged Chinese male with hepatitis B virus related hepatocellular carcinoma. He underwent partial hepatectomy and was diagnosed with emphysematous gastritis 4 days after index operation. …”
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