Showing 961 - 980 results of 5,161 for search '"Genomics"', query time: 0.07s Refine Results
  1. 961

    Exploration of migration directions in different populations of Eothenomys miletus in the Hengduan Mountains of Yunnan Province: a genome-based analysis by Yanfei Cai, Ting Jia, Wanlong Zhu, Wanlong Zhu, Wanlong Zhu

    Published 2025-01-01
    “…Additionally, we focused on identifying genomic signatures of selection and local adaptation among the different populations. …”
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    Article
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    Recombinant AAV batch profiling by nanopore sequencing elucidates product-related DNA impurities and vector genome length distribution by Florian Dunker-Seidler, Kathrin Breunig, Magdalena Haubner, Florian Sonntag, Markus Hörer, Rebecca C. Feiner

    Published 2025-03-01
    “…During production, recombinant adeno-associated virus (rAAV) capsids are equipped with heterogeneous genetic payloads including undesired DNA impurities as well as truncated vector genomes. Comprehensive analysis of encapsidated DNA by long-read next-generation sequencing is destined to guide platform optimization and provide crucial insights into safety of gene therapies. …”
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  5. 965

    Detecting gene copy number alterations by Oncomine Comprehensive genomic profiling in a comparative study on FFPE tumor samples by Fabio Bozzi, Elena Conca, Marco Silvestri, Gianpaolo Dagrada, Alice Ardore, Donata Penso, Daniele Lorenzini, Chiara Costanza Volpi, Desirè Viola Trupia, Adele Busico, Iolanda Capone, Federica Perrone, Elena Tamborini, Andrea Vingiani, Luca Agnelli, Giancarlo Pruneri

    Published 2025-02-01
    “…The introduction of other procedures, such as Next-Generation Sequencing has dramatically improved CNAs discovery at genome-wide level. The detection of CNAs by NGS in FFPE material is, nonetheless, a complex issue, which still requires validation studies. …”
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    Genetic analysis of ocular tumour-associated genes using large genomic datasets: insights into selection constraints and variant representation in the population by Jose S Pulido, Mandeep S Sagoo, Omar A Mahroo, Alexander Tanner

    Published 2024-04-01
    “…Background Large genomic databases enable genetic evaluation in terms of haploinsufficiency and prevalence of missense and synonymous variants. …”
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  15. 975

    Genome‐Wide Diversity in Lowland and Highland Maize Landraces From Southern South America: Population Genetics Insights to Assist Conservation by Pia Guadalupe Dominguez, Angela Veronica Gutierrez, Monica Irina Fass, Carla Valeria Filippi, Pablo Vera, Andrea Puebla, Raquel Alicia Defacio, Norma Beatriz Paniego, Veronica Viviana Lia

    Published 2024-12-01
    “…In this work, we use genome‐wide SNPs derived from ddRADseq to study the genetic diversity of individuals representing the five groups previously described for this area. …”
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    Genome-wide association study reveals major loci for resistance to septoria tritici blotch in a Tunisian durum wheat collection. by Maroua Ouaja, Bikash Ghimire, Bochra Amina Bahri, Medini Maher, Sahbi Ferjaoui, Sripada Udupa, Sonia Hamza

    Published 2025-01-01
    “…Using 7638 SNP markers, fifty-one marker-trait associations (MTAs) for STB resistance were identified by genome-wide association study (GWAS) at Bonferroni correction threshold of -log10(P) > 5.184 with phenotypic variance explained (PVE) reaching up to 58%. …”
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