CRISPR/Cas9-Based Protocol for Precise Genome Editing in Induced Pluripotent Stem Cells by Avinash Singh, Swathy Babu, Marcus Phan, Shauna Yuan

“…The advent of clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9-based genome editing has marked a significant advancement in genetic engineering technology. …”
Get full text

RNA modification writer-based immunological profile and genomic landscape of tumor microenvironment in lung adenocarcinoma by Qiang Xu, Lingyu Kong, Zhezhu Han, Xiuying Jin, Mingyan Ding, Zhengri Piao, Songnan Zhang

“…Methods We assessed the expression properties and genetic alterations of 26 RNA modification writers, including adenosine-to-inosine RNA editing, alternative polyadenylation, m1A, and m6A in 502 lung adenocarcinoma (LUAD) samples from the Cancer Genome Atlas (TCGA) datasets. Then, we used differentially expressed gene (DEGs) to develop a signature for predicting patient outcomes, which was dubbed the “writer score” for RNA-modified writers. …”
Get full text

An Integrating Approach for Genome-Wide Screening of MicroRNA Polymorphisms Mediated Drug Response Alterations by Xianyue Wang, Hong Jiang, Wei Wu, Rongxin Zhang, Lingxiang Wu, Huan Chen, Pengping Li, Yumin Nie, Jiaofang Shao, Yan Li, Xue Lin, Sali Lv, Qh Wang, Jie Hu

“…International Journal of Genomics…”
Get full text

Perspectives on Clinical Informatics: Integrating Large-Scale Clinical, Genomic, and Health Information for Clinical Care by In Young Choi, Tae-Min Kim, Myung Shin Kim, Seong K. Mun, Yeun-Jun Chung

“…Genomics & Informatics…”
Get full text

Integrating Genomic Data Sets for Knowledge Discovery: An Informed Approach to Management of Captive Endangered Species by Kristopher J. L. Irizarry, Doug Bryant, Jordan Kalish, Curtis Eng, Peggy L. Schmidt, Gini Barrett, Margaret C. Barr

“…International Journal of Genomics…”
Get full text

Genome-wide linkage mapping of Fusarium crown rot in common wheat (Triticum aestivum L.) by Faji Li, Can Guo, Qi Zhao, Weie Wen, Shengnan Zhai, Xinyou Cao, Cheng Liu, Dungong Cheng, Jun Guo, Yan Zi, Aifeng Liu, Jianmin Song, Jianjun Liu, Jindong Liu, Haosheng Li

Get full text

The Significant Effects of Threshold Selection for Advancing Nitrogen Use Efficiency in Whole Genome of Bread Wheat by Mohammad Bahman Sadeqi, Agim Ballvora, Said Dadshani, Md. Nurealam Siddiqui, Mohammad Kamruzzaman, Ahossi Patrice Koua, Jens Léon

Subjects: Get full text

Identification of deep intronic variants in junctional epidermolysis bullosa using genome sequencing and splicing assays by Fuying Chen, Ruoqu Wei, Yumeng Wang, Qiaoyu Cao, Jianbo Wang, Chenfei Wang, Dingjin Yao, Zhirong Yao, Cheng Ni, Ming Li

“…npj Genomic Medicine…”
Get full text

First report of the chloroplast and mitochondrial genomes of the Indian pitcher plant, Nepenthes khasiana Hook.f. by Ruchishree Konhar, Debasis Dash, Devendra Kumar Biswal

Subjects: Get full text

Whole genome re-sequencing in 437 tobacco germplasms identifies plant height candidate genes by Yanru Song, Yuanheng Wang, Ying Liu, Haozhen Li, Jie Ding, Xingfu Wu, Yongping Li, Fangchan Jiao, Long Yang

“…To better understand the population genetic structure and the genetic basis of plant height in tobacco, 437 tobacco germplasms were whole genome re-sequencing in this study. A total of 2,263,775 high-quality single nucleotide polymorphisms were identified. …”
Get full text

Decision impact studies, evidence of clinical utility for genomic assays in cancer: A scoping review. by Gillian Parker, Sarah Hunter, Samer Ghazi, Robin Z Hayeems, Francois Rousseau, Fiona A Miller

“…These studies aim to evaluate the impact of a genomic test on decision-making and appear to be a new form of evidence of clinical utility. …”
Get full text

The complete chloroplast genome sequences of monotypic genus Pseudogalium, and comparative analyses with its relative genera by Wei Yu, Xiao-Juan Li, Zhen Lv, Li-E Yang, De-Li Peng

Subjects: Get full text

Lung Cancer Prediction Using Neural Network Ensemble with Histogram of Oriented Gradient Genomic Features by Emmanuel Adetiba, Oludayo O. Olugbara

“…The Voss DNA encoding was used to map the nucleotide sequences of mutated and normal genomes to obtain the equivalent numerical genomic sequences for training the selected classifiers. …”
Get full text

Genome-wide association analysis and KASP markers development for protein quality traits in winter wheat by Yousheng Tian, Pengpeng Liu, Dezhen Kong, Yingbin Nie, Hongjun Xu, Xinnian Han, Wei Sang, Weihua Li

“…To expedite the breeding of wheat cultivars with high protein quality, it is necessary to genetically analyze the traits related to quality. A genome-wide association study (GWAS) was conducted to identify the genomic regions responsible for protein quality traits in winter wheat. …”
Get full text

Complete Genome Sequence Analysis of the First Imported Mpox Virus Clade Ib Variant in China by Yin Song, Yong Yan, Jingyu Xu, Shencong Lv, Ganglin Ren, Yamei Zhou, Wanchen Song, Rui Ge, Peihua Xu, Guoying Zhu, Zhongwen Chen

Subjects: Get full text

Recovery of nearly 3,000 archaeal genomes from 152 terrestrial geothermal spring metagenomes by Yan-Ling Qi, Hao-Tian Zhang, Meng Li, Wen-Jun Li, Zheng-Shuang Hua

“…The most abundant phyla of archaeal genomes were Thermoproteota, Thermoplasmatota, and Micrarchaeota. …”
Get full text

Genomic analysis of antimicrobial resistant Escherichia coli isolated from manure and manured agricultural grasslands by C. Tyrrell, C. M. Burgess, F. P. Brennan, D. Münzenmaier, D. Drissner, R. J. Leigh, F. Walsh

“…The E. coli isolates were phenotypically antimicrobial resistant, predominantly multidrug resistant. Whole genome sequencing identified 31 antimicrobial resistance genes, and mutations in the gyrA, parC, and parE genes, conferring fluoroquinolone resistance. …”
Get full text

Complete mitochondrial genome sequence analysis revealed double matrilineal components in Indian Ghoongroo pigs by Pranab Jyoti Das, Satish Kumar, Manasee Choudhury, Seema Rani Pegu, K. Meera, Rajib Deb, Sunil Kumar, Santanu Banik, Vivek Kumar Gupta

Subjects: Get full text

Molecular Crosstalking among Noncoding RNAs: A New Network Layer of Genome Regulation in Cancer by Marco Ragusa, Cristina Barbagallo, Duilia Brex, Angela Caponnetto, Matilde Cirnigliaro, Rosalia Battaglia, Davide Barbagallo, Cinzia Di Pietro, Michele Purrello

“…International Journal of Genomics…”
Get full text

Genomic Variability among Field Isolates and Laboratory-Adapted Strains of Leptospira borgpetersenii Serovar Hardjo by Alejandro Llanes, Carlos Mario Restrepo, Pablo Riesgo-Ferreiro, Sreekumari Rajeev

“…In order to better understand genetic variability among L. borgpetersenii serovar Hardjo isolates, we sequenced and compared the genomes of two laboratory-adapted strains and three abattoir-derived field isolates of L. borgpetersenii serovar Hardjo. …”
Get full text