Densely vascularized thick 3D tissue shows enhanced protein secretion constructed with intermittent positive pressure by Misako Katsuura, Jun Homma, Yuhei Higashi, Hidekazu Sekine, Tatsuya Shimizu

“…Furthermore, in vivo experiments showed that IPP-cultured cell sheets enhanced the secretion of Gaussian luciferase by genetically modified mesenchymal stem cells. These findings highlight the IPP method as a technique that simultaneously enables the thickening of planar tissues and the construction of vascular networks. …”
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Probing the potential of InDel polymorphisms on the molecular identification of cetaceans by Dafne Adriana Abreu dos Anjos, Rodrigo Goldenberg Barbosa, Anna Luiza dos Santos Donato, Elizeu Fagundes de Carvalho, Cesar Rogerio Leal do Amaral

“… Studies with cetaceans using degraded samples have faced challenges for molecular identification based on the barcoding methodology and other sequencing techniques due to the fragmented nature of the genetic material found on these samples. In this article, we evaluated the use of insertion–deletion regions for the molecular identification of cetaceans. …”
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Natural selection and evolution: evolving concepts by Andre J. van Wijnen, Eric Lewallen

“…Current evolutionary models incorporate different adaptive and non-adaptive processes based on molecular genetic changes and how DNA is modified over time in unicellular species, or in germline versus somatic cells in metazoan species. …”
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The mcpC mutant of Salmonella enteritidis exhibits attenuation and confers both immunogenicity and protective efficacy in mice by Lu Zhang, Li Chen, Xuqiang Zhang, Yang Li, Qingfeng Zheng, Yun Li, Ning Li, Qiumei Shi, Yanying Zhang, Tonglei Wu

“…The ΔmcpC offers strong immune protection in mice, providing a solid foundation for the development of genetically engineered attenuated live vaccines against SE.…”
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Identification of HOXA9 methylation as an epigenetic biomarker predicting prognosis and guiding treatment choice in acute myeloid leukemia by Fei Xie, Ting-juan Zhang, Xin-long Zhang, Zi-jun Xu, Liang Qiao, Yun Wang, Yang-jing Zhao, Jun Qian, Jing-dong Zhou

“…HOXA overexpression caused by genetic alterations, such as KMT2A rearrangements, NUP98- fusions and FLT3-ITD mutations, is frequently identified in AML. …”
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First detection and molecular characterization of porcine epidemic diarrhea virus (PEDV) in India: evidence of a new variant in Karnataka by Jagadish B. Hiremath, M. Swathi, R. Ramamoorthy, M. Shijili, Damini Sharma, Divakar Hemadri, H. B. Chethankumar, K. P. Suresh, Sharanagouda S. Patil, Shivasharanappa Nayakvadi, S. P. Satheesha, B. R. Shome, Baldev Raj Gulati

“…This study reports the first clinical outbreak of PED in India, followed by the detection and genetic characterization of PED virus (PEDV) during 2022-23. …”
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In silico evaluation of missense SNPs in cancer-associated Cystatin A protein and their potential to disrupt Cathepsin B interaction by Shafaat Hossain, Omar Hamza Bin Manjur, Mst Sharmin Sultana Shimu, Tamanna Sultana, Mustafizur Rahman Naim, Shahariar Siddique, Abdullah Al Mamun, Md Miftaur Rahman, Md Abu Saleh, Md Rakibul Hasan, Tania Rahman

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Aplikasi Pertimbangan Wisata di Pulau Lombok dengan Metode Fuzzy Mamdani & Algoritma Genetika by Zainul Harir, Ida Bagus Ketut Widiartha, Royana Afwani

“…An application that can help tourists in determining travel decision is mandatory.The application developed with Mamdani Fuzzy Logic and Genetic Algorithm to provide tourism recommendations. …”
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The application of emerging technologies for the quality and safety evaluation of oilseeds and edible oils by Xue Li, Wenwen Liu, Lu Xiao, Jie Zhao, Yan Chen, Liangxiao Zhang, Peiwu Li, Dolores Pérez-Marín, Xu Wang

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Vehicle-routing problem for low-carbon cold chain logistics based on the idea of cost–benefit by Yan Liu, Fengming Tao, Rui Zhu

“…Then, a hybrid algorithm called local search genetic algorithm (LSGA) is proposed, which amalgamates the destroy-repair operator with GA algorithm. …”
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Non-canonical lysosomal lipolysis drives mobilization of adipose tissue energy stores with fasting by GV Naveen Kumar, Rui-Sheng Wang, Ankit X. Sharma, Natalie L. David, Tânia Amorim, Daniel S. Sinden, Nandini K. Doshi, Martin Wabitsch, Sebastien Gingras, Asim Ejaz, J. Peter Rubin, Bradley A. Maron, Pouneh K. Fazeli, Matthew L. Steinhauser

“…We functionally tested lysosomal lipolysis with pharmacological and genetic approaches in mice and in murine and human adipocyte and adipose tissue explant culture, establishing dependency on lysosomal acid lipase (LIPA/LAL) and the microphthalmia/transcription factor E (MiT/TFE) family. …”
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Virus-inspired biogenic delivery system for advancing cancer therapy by Di Sun, Hao Liang, Qianwen Mu, Chengchao Chu, Gang Liu, Chao Liu

“…VLPs lack viral virulence, resulting from a viral genetic material deficiency. In vaccine research, Virus-mimic nanovesicles have been effectively verified against cancer via the immunogenicity and the pharmacological effect of drug molecules delivered to mediate an immune response in the body. …”
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Mechanisms of bacterial-to-host interaction and their disorders at inflammatory bowel diseases by Ye. A. Poluektova, O. S. Lyashenko, A. V. Korolev, O. S. Shifrin, V. T. Ivashkin

“…At IBD, all mechanisms providing interaction of bacterial cells with the host body are malfunc tioning to some extent, that, in combination to genetic predisposition to this disease, results in development of clinical symptoms and morphological changes.…”
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INTESTINAL MICROBIOME - A LEADING FACTOR IN HUMAN HEALTH AND DISEASES by E. Blum Hubert

“…Based on modern molecular, genetic, epigenetic microbiologic and biochemical studies it is, on the one hand, possible to identify disease-related point mutations and single nucleotide polymorphisms within genome-wide association analyses (GWAS). …”
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Autism common variants associated with white matter alterations at birth: cross-sectional fixel-based analyses of 221 European term-born neonates from the developing human connecto... by Hai Le, Alexandra F. Bonthrone, Alena Uus, Daphna Fenchel, Alexandra Lautarescu, Konstantina Dimitrakopoulou, A. David Edwards, Joseph V. Hajnal, Serena J. Counsell, Lucilio Cordero-Grande, Daan Christiaens, Dafnis Batalle, Maximilian Pietsch, Anthony N. Price, Hamel Patel, Charles Curtis, Harriet Cullen, Maria Deprez, Jacques-Donald Tournier

“…Despite the condition having high heritability, the relationship between autism common genetic variants and WM changes during this period remains unclear. …”
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Vascular malformations of the lungs and the liver at patient with hereditary hemorrhagic teleangiectasia by M. S. Zharkova, A. V. Lapshin, Ye. N. German, M. V. Mayevskaya, I. A. Sokolina, V. T. Ivashkin

“…Hereditary hemorrhagic teleangiectasia is infrequent genetic disease described by anomaly of vascular development and diversity of clinical symptoms. …”
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Harnessing artificial intelligence for predicting breast cancer recurrence: a systematic review of clinical and imaging data by Jaqueline Alvarenga Silveira, Alexandre Ray da Silva, Mariana Zuliani Theodoro de Lima

“…SVMs are effective with high-dimensional clinical data, while Neural Networks in genetic and molecular analysis. Despite these advancements, limitations such as dataset diversity, sample size, and evaluation standardization persist, emphasizing the need for further research. …”
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Prenatal Diagnosis of Zellweger Syndrome: Case Report by Bilgin Kütükcü, Meral Topçu, Sinan Beksaç, Ronald J. Wanders

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Deciphering Regulatory Networks Governing Seedling Emergence in Deep-Sown Direct-Seeded Rice Cultivation by Jasneet Singh, Nitika Sandhu, Aman Kumar, Om Prakash Raigar, Sutej Bains, Gaurav Augustine, Muskan Gupta, Ekta Kharche, Anu Kalia, Navtej Singh Bains, Arvind Kumar

“…The study brings us closer to understanding the genetic control of seedling emergence under deep sown conditions. …”
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Exploratory analysis of molecular traits of the mitochondrial DNA of leafcutting ants to infer taxonomic characters towards an integrative taxonomy by Perpetua Ndubuisi Onyinyechi, Natália Martins Travenzoli, Maykon Passos Cristiano, Danon Clemes Cardoso

“…In the present study we propose using exploratory analysis of genetic markers to obtain additional information from the comparison of sequences among species as molecular traits (MTs). …”
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