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521
Development of animal models to study aggressive thyroid cancers
Published 2025-02-01“…However, as our understanding of the genetic alterations driving thyroid cancer has expanded, more sophisticated genetic engineering techniques have been employed to create models with thyroid-specific expression of these driver mutations. …”
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522
Cryptic coral community composition across environmental gradients.
Published 2025-01-01“…Cryptic genetic variation is increasingly being identified in numerous coral species, with prior research indicating that different cryptic genetic lineages can exhibit varied responses to environmental changes. …”
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523
The theses for MD degree
Published 2010-08-01“…Stepanova – Clinical and genetic aspects of a Crohn’s disease.…”
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524
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525
New Plants for Florida: Grape
Published 2003-08-01“…Developments of biotechnological procedures to facilitate genetic improvement of grape began at the Leesburg site in 1984 and continue at Apopka, Florida. …”
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526
Prmt5 is essential for intestinal stem cell maintenance and homeostasis
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527
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528
Personalized medicine: An alternative for cancer treatment
Published 2024-01-01“…Personalized medicine allows for the creation of focused medicines that address specific gene mutations by leveraging knowledge about a patient's cancer, including its genetic makeup. Ongoing research seeks to detect gene modifications in diverse cancer types, produce novel diagnostic tools, and develop treatments that particularly target these genetic changes. …”
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529
Population features of prevalence and clinical-diagnostic role of NOD2 gene polymorphisms associated with Crohn’s disease
Published 2018-08-01“…According to literature data analysis it is possible to conclude that there are clear populationrelated features of the prevalence, clinical and diagnostic role of NOD2 genetic polymorphism associated to Crohn's disease that requires development of the international data bank of all genetic nucleotide polymorphisms associated to various stages of CD pathogenesis in different countries and populations. …”
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530
Modifiable factors for irritable bowel syndrome: evidence from Mendelian randomisation approach
Published 2025-01-01“…Robust associations were found between multisite chronic pain and both IBS and coexisting disorders.Conclusions Our study identified a comprehensive array of potential modifiable factors and coexisting disorders associated with IBS, supported by genetic evidence, including genetic correlation and multiple MR analyses. …”
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531
Population structure, selection signal and introgression of gamecocks revealed by whole genome sequencing
Published 2025-02-01“…However, the single or multiple origin of global gamecocks has not been fully established and much remains unknown about genetic introgression events between gamecocks and other chickens. …”
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532
Rescue of common and rare exon 2 skipping variants of the GAA gene using modified U1 snRNA
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533
Engineering artificial photosynthetic life-forms through endosymbiosis
Published 2022-04-01“…Here, we design and engineer artificial, genetically tractable, photosynthetic endosymbiosis between photosynthetic cyanobacteria and budding yeasts. …”
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534
GWSF-EuSWAP70 gene expression to enhance gray mold resistance in Arabidopsis thaliana
Published 2025-02-01“…Traditional breeding methods are very time-consuming; therefore, plant genetic engineering has emerged as a promising approach for plant pathogen management. …”
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535
Extensive paralogism in the environmental pangenome: a key factor in the ecological success of natural SAR11 populations
Published 2025-02-01“…Despite their abundance, challenges in recovering the full genetic diversity of natural populations have hindered our understanding of the eco-evolutionary mechanisms driving intra-species variation. …”
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536
Autism spectrum disorder common variants associated with regional lobe volume variations at birth: cross-sectional study in 273 European term neonates in developing human connectom...
Published 2025-02-01“…This preliminary result suggests the potential involvement of ASD common genetic variants in early structural variations linked to ASD.…”
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537
A review of the intertidal Medon Stephens (Coleoptera, Staphylinidae, Paederinae) with description of a new species on the East Asian coasts
Published 2025-02-01“…Detailed comparison of morphological characters and molecular analyses based on genetic divergence and gene tree monophyly for species delimitation support the validity of the new species. …”
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538
Canine circovirus: an emerging virus of dogs and wild canids
Published 2025-02-01“…Belonging to the Circoviridae family, CanineCV exhibits genetic variability and has been associated with various clinical manifestations, including gastroenteritis, respiratory symptoms, and neurological disorders. …”
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539
Whole Exome Sequencing Reveals Rare Variants in Genes Associated with Metabolic Disorders in Women with PCOS
Published 2023-10-01“…Background: Polycystic ovary syndrome (PCOS) is a complex genetic trait, the pathogenesis of which is governed by an interplay of genetic and epigenetic factors. …”
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540
Methodical approaches in experimental modelling of non-alcoholic fatty liver disease
Published 2015-09-01“…Genetic models are subdivided into two categories. …”
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