Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome by Kira A Cozzolino, Lynn Sanford, Samuel Hunter, Kayla Molison, Benjamin Erickson, Meaghan CS Courvan, Taylor Jones, Deepa Ajit, Matthew D Galbraith, Joaquín M Espinosa, David Bentley, Mary Ann Allen, Robin D Dowell, Dylan J Taatjes

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Metabolic Risk Factors and Their Impact on Quality of Life in Patients with Pancreatic Cancer, Acute or Exacerbated Chronic Pancreatitis by I. N. Grigor’eva, O. V. Efimova, N. L. Tov, T. S. Suvorova, D. L. Nepomnyashchikh

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Clinical Recommendations of Russian Gastroenterological Association and RENDO Endoscopic Society on Diagnosis and Treatment of Gastritis and Duodenitis by V. T. Ivashkin, I. V. Maev, T. L. Lapina, E. D. Fedorov, A. A. Sheptulin, A. S. Trukhmanov, A. V. Kononov, R. A. Abdulkhakov, O. P. Alexeeva, S. A. Alekseenko, D. N. Andreev, E. K. Baranskaya, N. N. Dekhnich, I. L. Klyaritskaya, R. S. Kozlov, E. A. Kogan, M. P. Korolev, N. V. Korochanskaya, S. A. Kurilovich, M. A. Livsan, M. F. Osipenko, P. V. Pavlov, S. S. Pirogov, A. S. Sarsenbaeva, V. I. Simanenkov, A. S. Tertychny, A. V. Tkachev, Yu. P. Uspensky, I. B. Khlynov, V. V. Tsukanov

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Electronic tools to improve procalcitonin utilization by Julia A. Hisey, Grace K. Mahowald, Nicole V. Tolan, Phillip Kang, Ramy H. Elshaboury, Anand S. Dighe, Kent B. Lewandrowski, Christiana A. Demetriou, Stacy E.F. Melanson, Alyssa R. Letourneau

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Deep learning-based prediction of autoimmune diseases by Donghong Yang, Xin Peng, Senlin Zheng, Shenglan Peng

“…Their etiology involves multiple factors such as genetics, environmental factors, and abnormalities in immune cells, making prediction and treatment challenging. …”
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Sex ratio at birth in Kogi state, North-Central Nigeria by Adekunle Bakare, Deborah Peter, Motunrayo Mojoyin Coker, Silas Fagbenro, Okunola A. Alabi

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Development of a Model Mutagenesis System for Snapdragon by Zhaoyuan Lian, Heqiang Huo, Sandra B. Wilson, Jianjun Chen

“…With all of their aesthetic attributes and versatility, snapdragons are also an important model system for genetics and molecular studies of various plant processes.   …”
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Sarcoidosis: molecular mechanisms and therapeutic strategies by Danfeng Xu, Xiaohua Tao, Yibin Fan, Yan Teng

“…Recent studies have made outstanding achievement in understanding the pathology, etiology, genetics, and immune dysregulation involved in granuloma formation of sarcoidosis. …”
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ARV1 p.Gln62Ter, a novel mutation linked to developmental and epileptic encephalopathy-38 by Mostafa Neissi, Ayoob Radhi Al-Zaalan, Misagh Mohammadi-Asl, Mojdeh Roghani, Javad Mohammadi-Asl, Kamele Jorfi

“…These findings contribute to the understanding of the genetic spectrum of developmental and epileptic encephalopathy-38. …”
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An Integrated Database for Exploring Alternative Promoters in Animals by Feiyang Xue, Yuqin Yan, Weiwei Jin, Haotian Zhu, Yanbo Yang, Zhanhui Yu, Xuewen Xu, Jing Gong, Xiaohui Niu

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Chromosomal genome assembly resolves drug resistance loci in the parasitic nematode Teladorsagia circumcincta. by Jennifer McIntyre, Alison Morrison, Kirsty Maitland, Duncan Berger, Daniel R G Price, Sam Dougan, Dionysis Grigoriadis, Alan Tracey, Nancy Holroyd, Katie Bull, Hannah Rose Vineer, Mike J Glover, Eric R Morgan, Alasdair J Nisbet, Tom N McNeilly, Yvonne Bartley, Neil Sargison, Dave Bartley, Matt Berriman, James A Cotton, Eileen Devaney, Roz Laing, Stephen R Doyle

“…These insights into contemporary and historic genetic selection further emphasise the importance of contiguous genome assemblies in interpreting genome-wide genetic variation associated with drug resistance and identifying key loci to prioritise in developing diagnostic markers of anthelmintic resistance to support parasite control.…”
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Commentary on the published position statement regarding the pathogenesis of fetal basal ganglia- thalamic hypoxic-ischaemic injury by J Anthony, J Smith, L Murray, G F Kirsten, G Gericke, Y Kara, V Davies, D Pearce, R van Toorn, M M Lippert, J W Lotz, S Andronikou, B Alheit, L van Wyk, A S Ebrahim, B S Schifrin

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Burden of benign prostatic hyperplasia in the Middle East and North Africa Region, 1990–2021 by Saeid Safiri, Fikrettin Şahin, Reza Aletaha, Mark J. M. Sullman, Reza Shekarriz-Foumani, Ali-Asghar Kolahi

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Factors Determining Parental Attitudes Towards Termination of Pregnancy in Prenatally Detected Down Syndrome by Ömer Talip Turhan, Mehmet Serdar Kütük, Ruksan Büyükoğlan, Mehmet Dolanbay, Mahmut Tuncay Özgün, Özlem Turhan, Mürşide Şahin

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The Use of Fluorescence In situ Hybridisation in the Diagnosis of Hidden Mosaicism in Egyptian Patients with Turner Syndrome by Heba Mohamed Ossama, Soha Kholeif, Ghada Mohamed Elhady

“…Settings and Design: This cross-sectional, descriptive study was performed in Human Genetics Department, Medical Research Institute, Alexandria University. …”
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In vitro micropropagation protocols for two endangered Dianthus species - via in vitro culture for conservation and recultivation purposes by Dóra Farkas, Judit Csabai, Angéla Kolesnyk, Pál Szarvas, Judit Dobránszki

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Effective gene therapy for metachromatic leukodystrophy achieved with minimal lentiviral genomic integrations by Lucas Tricoli, Sunetra Sase, Julia L. Hacker, Vi Pham, Maxwell Chappell, Laura Breda, Stephanie N. Hurwitz, Naoto Tanaka, Carlo Castruccio Castracani, Amaliris Guerra, Zhongqi Hou, Lars Schlotawa, Karthikeyan Radhakrishnan, Matthew Hogenauer, Aoife Roche, John Everett, Frederic Bushman, Peter Kurre, Rebecca Ahrens-Nicklas, Laura A. Adang, Adeline L. Vanderver, Stefano Rivella

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NTRK-rearranged spindle cell tumor with SPECC1L-NTRK3 fusion in the thoracic spine: a case report by Mi Zhou, Huaiyuan Xu, Jianxiong Niu, Qibing Yang, Anqi Wang, Hao Wu, Xiangqin Wang, Meng Yang, Jinxin Hu, Qinglian Tang, Jin Wang

“…This case underscores the diagnostic and therapeutic importance of next-generation sequencing in identifying tumor-specific genetic alterations and selecting targeted therapies. …”
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Bioactive molecules from soybeans (Glycine max) with anti-type 2 diabetes activity: a systematic review by Adekunle Babajide Rowaiye, Lorretha Chinonye Emenyonu, Ezinne Janefrances Nwonu, Okiemute Ajiroghene Okpalefe, Joseph Akwoba Ogugua, Victor Oluwatoyin Akinseye, Gordon Chukwuma Ibeanu

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