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Tumor Necrosis Factor-Alpha Gene Promoter Region Polymorphism and the Risk of Coronary Heart Disease
Published 2013-01-01Get full text
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222
A universal and wide-range cytosine base editor via domain-inlaid and fidelity-optimized CRISPR-FrCas9
Published 2025-02-01“…Abstract CRISPR-based base editor (BE) offer diverse editing options for genetic engineering of microorganisms, but its application is limited by protospacer adjacent motif (PAM) sequences, context preference, editing window, and off-target effects. …”
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223
Non-viral systems for intracellular delivery of genome editing tools
Published 2024-04-01“…A hallmark of the last decades is an extensive development of genome editing systems and technologies propelling genetic engineering to the next level. Specific and efficient delivery of genome editing tools to target cells is one of the key elements of such technologies. …”
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224
A pathogenic COL7A1 variant highlights semi-dominant inheritance in dystrophic epidermolysis bullosa
Published 2025-02-01Get full text
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225
Potential and development of cellular vesicle vaccines in cancer immunotherapy
Published 2025-01-01“…This paper presents the advantages of these three bacteria/extracellular vesicles as cancer vaccines and discusses the potential applications of functionally modified extracellular vesicles as cancer vaccines after cellular engineering or genetic engineering, as well as current clinical trials of extracellular vesicle vaccines. …”
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226
Escherichia coli stress response systems and their reaction to terahertz radiation
Published 2017-02-01“…E. coli is the most simple and convenient model object for studying the effects of terahertz radiation: both its genetics and metabolism are well studied, and it is easily amenable to genetic engineering allowing one to create biosensors using promoters of genes activated by certain stress factors and the reporter GFP protein. …”
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227
Plant genome modification: from induced mutagenesis to genome editing
Published 2022-11-01“…A new technology of genetic engineering and transgenesis enabled us to radically reduce the time required to obtain a new genetically-modified cultivar to one generation and make the modification process more effective and targeted. …”
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Multi-Omics Insights into Regulatory Mechanisms Underlying Differential Deposition of Intramuscular and Abdominal Fat in Chickens
Published 2025-01-01“…These insights provide a valuable theoretical foundation for the genetic engineering of high-quality and high-yielding chicken breeds.…”
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Somatic Transformations in the Context of Antropotechnogynesis at the Modern Stage
Published 2021-06-01“…They are divided into two main groups: intra-structural, substantial, related to techno-modification of the human body directly through biotechnology and genetic engineering, cyborgization, xenotransplantation, Hi-Hume connection with Hi-Tech and others, and external-contextual, when under the influence of pancommunication and hybridization the environment is increasingly mentalized and somatized, and modern technologies are gradually transformed into the social body of man.…”
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232
Haploid biotechnology as a tool for creating a selection material for sugar beets
Published 2022-01-01“…The integration of haploid production techniques together with other available biotechnological tools such as marker selection (MAS), induced mutagenesis and genetic engineering technologies can significantly accelerate crop breeding. …”
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233
Estimating the Genetic Diversity of Oranges Citrus spp. in South Sulawesi, Indonesia, Using RAPD Markers
Published 2023-01-01“…The dendrogram diagram can serve as a basis for selecting desired plant traits in the improvement of plant characteristics through both conventional breeding and genetic engineering activities.…”
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234
A novel microbial consortium from sheep compost for decolorization and degradation of Congo red
Published 2019-01-01Get full text
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235
Deciphering the Regulatory Network of Some Key Drought-responsive Genes and microRNAs in Canola
Published 2024-02-01“…They are regulated by important miRNAs in a complex regulatory network that worth being considered in genetic engineering programs of Canola.…”
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236
A parallel bioreactor strategy to rapidly determine growth-coupling relationships for bioproduction: a mevalonate case study
Published 2025-01-01“…Conclusions We demonstrated the power of using parallel bioreactors to assess productivity and the growth-coupling relationship between growth rate and product yield coefficient of mevalonate production. Using genetic engineering, our resultant strain demonstrated rapid mevalonate formation without the unwanted byproduct acetate. …”
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237
Bioengineering in Solid-State Fermentation for next sustainable food bioprocessing
Published 2025-01-01“…A review of bioengineering strategies that optimize microbial growth and metabolite production in SSF systems is presented in this chapter, including novel bioreactor designs and genetic engineering of microorganisms combined with metabolic engineering. …”
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238
RNA-Seq Assembly and Differential Transcriptome Analysis of Korean Medicinal Herb var.
Published 2018-12-01“…The data shall not only be useful to focus more deeply on the genes related to product medicinal metabolite including flavolignan but also to study the functional genomics for genetic engineering of C. japonicum.…”
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239
Rosuvastatin effects on the HDL proteome in hyperlipidemic patients
Published 2023-09-01Get full text
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240
Examining the Gm18 and mG Modification Positions in tRNA Sequences
Published 2014-06-01Get full text
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