Evaluation of exo-long noncoding RNA MALAT1 in OSCC in comparison to dysplastic and normal: A cross-sectional study by Ramya Sekar, Selvaraj Jayaraman, VishnuPriya Veeraraghavan, Kalaiselvi Krishnamoorthy, Shubhra Chauhan Aramanai, Sathan Raj Natarajan

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MSC-exosomes pretreated by Danshensu extracts pretreating to target the hsa-miR-27a-5p and STAT3-SHANK2 to enhanced antifibrotic therapy by Jiabin Liang, Jingxiu Zhao, Lin Yang, Qian Wang, Jing Liao, Jianhao Li, Weizhao Zhuang, Fanghong Li, Jinxian He, Yukuan Tang, Hanwei Chen, Chen Huang

“…Additionally, the differential expression of miRNAs between DSS-Exo and Exo was explored and validation of key miRNA. …”
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Mesenchymal stem cells-derived exosomes attenuate mouse non-heart-beating liver transplantation through Mir-17-5p-regulated Kupffer cell pyroptosis by Yang Tian, Ming Jin, Nanwei Ye, Zhenzhen Gao, Yuancong Jiang, Sheng Yan

“…Mesenchymal stem cells-derived exosomes (MSCs-Exo) have been extensively investigated in liver diseases. …”
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iPSC-derived exosomes as amphotericin B carriers: a promising approach to combat cryptococcal meningitis by Jingyu Zhao, Jingyu Zhao, Wei Fang, Yangjie Gao, Jiquan Chen, Guizhen Wang, Julin Gu

“…In a C57BL/6 J mouse model of cryptococcal infection, treatment groups (AmB, iPSC-Exo/AmB, and iPSC-Exo) were administered corresponding drugs, with blood and brain samples collected for analysis. …”
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Exosomal mir-126-3p derived from endothelial cells induces ion channel dysfunction by targeting RGS3 signaling in cardiomyocytes: a novel mechanism in Takotsubo cardiomyopathy by Xuehui Fan, Guoqiang Yang, Yinuo Wang, Haojie Shi, Katja Nitschke, Katherine Sattler, Mohammad Abumayyaleh, Lukas Cyganek, Philipp Nuhn, Thomas Worst, Bin Liao, Gergana Dobreva, Daniel Duerschmied, Xiaobo Zhou, Ibrahim El-Battrawy, Ibrahim Akin

“…Epi exposure led to elevated levels of miR-126-3p in both HCMECs and their exosomes. Exo enriched with miR-126-3p demonstrated similar effects as Epi-exo, establishing the crucial role of miR-126-3p in the mechanism of Epi-exo. …”
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Exosome-based targeted delivery of NF-κB ameliorates age-related neuroinflammation in the aged mouse brain by Chae-Jeong Lee, Seung Hyun Jang, Jiwoo Lim, Hyunju Park, So-Hee Ahn, Seon Young Park, Hyangmi Seo, Soo-Jin Song, Jung-A Shin, Chulhee Choi, Heon Yung Gee, Youn-Hee Choi

“…Thus, our findings highlight Exo-srIκB as a potential therapeutic agent for treating age-related neuroinflammation.…”
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Signal and modulating role of enzymes of digestive glands by G. F. Korotko

“…They carry out also signaling role in modulation of exo- and endocrine secretions of digestive glands and motor activity of gastro-intestinal tract. …”
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Molecular basis for azetidine-2-carboxylic acid biosynthesis by Tim J. Klaubert, Jonas Gellner, Charles Bernard, Juliana Effert, Carine Lombard, Ville R. I. Kaila, Helge B. Bode, Yanyan Li, Michael Groll

“…AZE synthases catalyse the intramolecular 4-exo-tet cyclisation of S-adenosylmethionine (SAM), yielding a highly strained heterocycle. …”
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Direct imaging of exoplanets: Legacy and prospects by Chauvin, Gael

“…On the timescale of a human Life, we may well be witnessing the first discovery of an exoplanet and the first detection of indices of life in the atmosphere of a nearby exo-Earth!…”
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Enhancing Miscanthus floridulus remediation of soil cadmium using Beauveria bassiana FE14: Plant growth promotion and microbial interactions by Ying Wang, Sha Xiang, Rui Chen, Liang Chen, Wendi Lan, Jun Fang, Yunhua Xiao

“…In addition, the key genera (including Sphingomonas, unclassified_Comamonadaceae, Massilia, Bradyrhizobium, and Paraglomus) and key genes/enzymes (including cadC, zinc transporter, zinc and cadmium transporter, exoZ/Y/Z, catalase-peroxidase, superoxide dismutase, nitrite reductase, acid phosphatase, etc.) were involved in promoting plant growth and alleviating Cd stress. …”
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The stability of anisotropic compact stars influenced by dark matter under teleparallel gravity: an extended gravitational deformation approach by Sneha Pradhan, Piyali Bhar, Sanjay Mandal, P. K. Sahoo, Kazuharu Bamba

“…To validate our findings, we compare our model predictions with observational constraints, including GW190814 (with a mass range of $$2.5-2.67 M_{\odot }$$ 2.5 - 2.67 M ⊙ ) and neutron stars (NSTRs) such as EXO 1785-248 [mass= $$1.3_{-0.2}^{+0.2}~M_{\odot }$$ 1 . 3 - 0.2 + 0.2 M ⊙ ], 4U 1608-52 [mass= $$1.74_{-0.14}^{+0.14}~M_{\odot }$$ 1 . 74 - 0.14 + 0.14 M ⊙ ], and PSR J0952-0607 [mass= $$2.35_{-0.17}^{+0.17}~M_{\odot }$$ 2 . 35 - 0.17 + 0.17 M ⊙ ]. …”
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Pancreas Proapoptotic Proteases in Patients with Chronic Pancreatitis by N. B. Gubegritz, E. A. Krylova, Yu. A. Gaidar

“…This proves the existence of various apoptosis mechanisms in the exo- and endocrine portions of the pancreas.…”
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Exploring RNA cargo in extracellular vesicles for pleural mesothelioma detection by Agnieszka Kraft, Michaela B. Kirschner, Vanessa Orlowski, Manuel Ronner, Caroline Bodmer, Valentina Boeva, Isabelle Opitz, Mayura Meerang

“…EVs were isolated from the supernatant using Qiagen exoEasy Maxi kit. RNA isolation from EVs was done using the mirVana PARIS kit. …”
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Exosomes derived from liver failure patients’ plasma stimulated mesenchymal stem cells alleviate acute liver failure by Zhuoran Wang, Jun Ling, Shaoli You, Bing Zhu

“…In this study, we investigated the therapeutic potential of exosomes from MSCs stimulated with plasma from patients with liver failure (LF-Exos). Methods Untreated exosomes (NC-Exos) and LF-Exos were extracted and characterized by nanoparticle tracking analysis (NTA), transmission electron microscopy (TEM), western blotting, and miRNA sequencing. …”
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Therapeutic potential of mesenchymal stem cell-derived extracellular vesicles in ischemic stroke: A meta-analysis of preclinical studies by Xiaoming Zhang, Yibing Guo, Kun Fang, Xiangqian Huang, Duo Lan, Mengqi Wang, Lina Jia, Xunming Ji, Ran Meng, Da Zhou

“…This study aims to systematically evaluate the therapeutic effects of mesenchymal stem cell-derived exosomes (MSC-Exos) on IS outcomes in rodent models. Methods: A comprehensive literature search was conducted across multiple databases to identify studies investigating the effects of MSC-Exos on rodent models of IS. …”
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The role of natural exosomes from SHED-MSC in immunoregulation of M0/M1 polarized macrophage cells by Ali Fallah, Abasalt Hosseinzadeh Colagar, Ayyoob Khosravi, Ayyoob Khosravi, Azadeh Mohammad-Hasani, Azadeh Mohammad-Hasani, Mohsen Saeidi, Mohsen Saeidi

“…IntroductionExosomes (EXOs) as a targeted cell-free therapy could offer a new therapeutic strategy for immune-mediated inflammatory diseases, due to their stability and ease of storage and handling. …”
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