Phenotypic and genetic extended spectrum beta lactamase profiles of bacterial isolates from ICU in tertiary level hospital in Kenya [version 2; peer review: 2 approved] by Edwin O. Magomere, Lucy Muchiri, Leon Otieno, Frank G. Onyambu, Ali Kassim, Job Mwale, Brian Maina

“…Other isolates that were present at frequencies more than 15% are Klebsiella pneumoniae and Escherichia. coli. A. baumaniii is known to be a notorious bacterium in ICU due to its multidrug resistance nature. …”
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Therapeutic Values of Earthworm Species Extract from Azad Kashmir as Anticoagulant, Antibacterial, and Antioxidant Agents by Rozina Ghulam Mustafa, Andleeb Dr Saiqa, Jorge Domínguez, Madiha Jamil, Saira Manzoor, Samna Wazir, Bushra Shaheen, Asma Parveen, Rida Khan, Shaukat Ali, Nazish Mazhar Ali, Fatima Jalal, Sadaf Azad Raja

“…Antibacterial effect analysis of earthworm species was done against fourteen bacterial pathogens, i.e., Escherichia coli, Serratia marcescens, Streptococcus pyogenes, Staphylococcus epidermidis, Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa (1), Salmonella typhimurium, Shigella flexneri, Enterobacter amnigenus, Serratia odorifera, Pseudomonas aeruginosa (2), Staphylococcus warneri, and Lactobacillus curvatus, via agar well diffusion, crystal violet, MTT, agar disc diffusion, and direct bioautography assays. …”
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Prevalence of Bacterial Urinary Tract Infections and Associated Factors among Patients Attending Hospitals in Bushenyi District, Uganda by Martin Odoki, Adamu Almustapha Aliero, Julius Tibyangye, Josephat Nyabayo Maniga, Eddie Wampande, Charles Drago Kato, Ezera Agwu, Joel Bazira

“…The study revealed 86/267 (32.2%) UTI prevalence among patients attending hospitals in Bushenyi District, Uganda. Escherichia coli was the most prevalent bacterial uropathogen with 36/86 (41.9%) followed by Staphylococcus aureus 27/86 (31.4%), Klebsiella pneumoniae 10/86 (11.6%), Klebsiella oxytoca 6/86 (7.0%), Proteus mirabilis 3/86 (3.5%), Enterococcus faecalis 3/86 (3.5%), and Proteus vulgaris 1/86 (1.2%). …”
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Fecal carriage of carbapenemase and AmpC-β-lactamase producers among extended spectrum β-Lactamase-producing E. coli and Klebsiella spp. isolates in patients attending hospitals by Zakaria Garba, Isidore J. O. Bonkoungou, Namwin Siourimè Somda, Magloire H. Natama, Georges Somé, Lassana Sangaré, Nicolas Barro, Halidou Tinto

“…Abstract Background Extended-spectrum β-lactamase-producing Enterobacterales (ESBL-PE), particularly Escherichia coli and Klebsiella pneumoniae, have been consistently associated with treatment failure, high mortality and morbidity. …”
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Short path molecular distillation of the essential oil from Pinus roxburghii oleoresin affords volatile fractions with powerful antioxidant and antimicrobial activities comparable... by Muhammad Adnan Ayub, Hawraz Ibrahim M. Amin, Rameen Waseem, Kamaran Younis M. Amin, Muhammad Asif Hanif, Amjad Hussain, Kovan Dilawar Issa, Jorge Ramírez, Chabaco Armijos, Muhammad Zubair, Giovanni Vidari

“…In addition, the antimicrobial activity of the fractions and sub-fractions against the bacteria Pasteurella multocida, Staphylococcus aureus, Escherichia coli, and Bacillus subtilis, and the fungal strains Fusarium solani, Alternaria alternata, Aspergillus flavus, and Aspergillus niger, was measured by the agar well diffusion method, the microdilution broth assay and the resazurin microtiter plate test. …”
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Cooperative mechanisms of LexA and HtpG in the regulation of virulence gene expression in Pseudomonas plecoglossicida by Rongchao He, Yanfei Zuo, Qiu Li, Qingpi Yan, Lixing Huang

“…LexA is a well-known transcriptional repressor of DNA repair genes induced by DNA damage in Escherichia coli and other bacterial species. Recently, this paradigm—that LexA solely regulates the SOS response—has been challenged as studies reveal its involvement in various biological functions linked to virulence. …”
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Characterization of the Vibrio anguillarum VaRyhB regulon and role in pathogenesis by Yingjie Li, Xinran Yu, Peng Li, Xin Li, Lushan Wang

“…ResultsThe small RNA called VaRyhB identified in V. anguillarum strain 775 is significantly longer than that in Escherichia coli. Transcriptomic analysis revealed that VaRyhB is critical for iron homeostasis under limited iron conditions, and deletion of VaRyhB resulted in lower expression levels of certain genes for siderophore biosynthesis and transport, thereby leading to impaired growth, reduced siderophore production, and decreased pathogenesis. …”
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Ocorrência de Infecção do Trato Urinário em Pacientes após Transplante Renal by Elisa Camila de Souza e Silva, Sibely de Paula Guilherme, Cristina Nantes Miranda, André Luiz Silva Alvim, Gustavo Fernandes Ferreira, Thiago Cesar Nascimento, Ana Paula Machado da Rocha

“…As infecções são causadas por bactérias resistentes aos antibióticos trimetoprima e sulfametoxazol, como Escherichia coli, Klebsiella sp. e Serratia sp. Conclusão:  O trabalho aponta que é necessário melhorar a manipulação dos pacientes e materiais, visando reduzir as infecções, principalmente em função do alto grau de resistência a antibióticos dos microrganismos observados. …”
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Asymptomatic Bacteriuria among Pregnant Women in Addis Ababa, Ethiopia: Prevalence, Causal Agents, and Their Antimicrobial Susceptibility by Ketema Bizuwork, Haile Alemayehu, Girmay Medhin, Wondwossen Amogne, Tadesse Eguale

“…The most frequently isolated bacterial species were Escherichia coli 17 (30.2%), Proteus 13 (23.2%), and Enterococcus 11 (19.6%). …”
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Constructing the constitutively active ribosomal protein S6 kinase 2 from <i>Arabidopsis thaliana</i> (AtRPS6K2) and testing its activity <i>in vitro</i> by A. V. Zhigailov, G. E. Stanbekova, D. K. Beisenov, A. S. Nizkorodova, N. S. Polimbetova, B. K. Iskakov

“…After the expression of both natural and mutated cDNAs in Escherichia coli cells, two recombinant proteins were isolated: native AtRPS6K2 and presumably constitutively active AtRPS6K2(S296E, S437E, T455E). …”
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Antibacterial Effect of Luma apiculata (DC.) Burret Extracts in Clinically Important Bacteria by Tiare Araya-Contreras, Rhonda Veas, Carlos A. Escobar, Pamela Machuca, Mauricio Bittner

“…Then, the extract’s antibacterial activity was tested against Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus saprophyticus, Enterococcus sp, Acinetobacter baumanii, Pseudomonas aeruginosa, and Escherichia coli. Results. The hexane extract of L. apiculata leaves resulted to be active against all bacteria tested. …”
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A Nanoparticle Comprising the Receptor-Binding Domains of Norovirus and <i>Plasmodium</i> as a Combination Vaccine Candidate by Ming Xia, Pengwei Huang, Frank S. Vago, Wen Jiang, Xi Jiang, Ming Tan

“…The P-αTSR fusion proteins were produced in the <i>Escherichia coli</i> expression system and the fusion protein self-assembled into the P₂₄-αTSR NP. …”
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Phenolic Content and Antioxidant and Antimicrobial Activities of Malva sylvestris L., Malva oxyloba Boiss., Malva parviflora L., and Malva aegyptia L. Leaves Extract by Khalid A. Shadid, Ashok K. Shakya, Rajashri R. Naik, Nidal Jaradat, Husni S. Farah, Naeem Shalan, Nooman A. Khalaf, Ghaleb A. Oriquat

“…., and Malva aegyptia L.) and also towards assessing their antibacterial activity against one Gram-positive isolate (Staphylococcus aureus) and four Gram-negative strains Escherichia coli, Pseudomonas aeruginosa, Shigella sonnei, and Proteus vulgaris. …”
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TLR4 Inhibition Attenuated LPS‐Induced Proinflammatory Signaling and Cytokine Release in Mouse Hearts and Cardiomyocytes by Christine W. Wiger, Trine Ranheim, Henriette Arnesen, Jarle Vaage, Søren E. Pischke, Arne Yndestad, Kåre‐Olav Stensløkken, May‐Kristin Torp

“…We hypothesized that TLR4 inhibition reduces proinflammatory signaling and cytokine release in: (1) LPS or Escherichia coli‐treated isolated mouse heart; (2) LPS‐treated mouse primary adult cardiomyocytes; and (3) the isolated heart during ischemia–reperfusion. …”
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Clostridium Scindens Protects Against Vancomycin‐Induced Cholestasis and Liver Fibrosis by Activating Intestinal FXR‐FGF15/19 Signaling by Jintao Xiao, Yanliang Hou, Xingyang Luo, Yuhao Zhu, Wenhu Li, Bingbing Li, LinXiang Zhou, Xia Chen, Ying Guo, Xiaomei Zhang, Haiyue He, Xiaowei Liu

“…Similar effects are observed in mice treated with engineered Escherichia coli Nissle 1917 that are capable of expressing bile acid 7α‐dehydratas (BaiE) from C. scindens (EcN‐BaiE). …”
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Reverse transcriptase inhibitors diminish systemic proinflammatory responses to bacterial pathogens by Karthik Hullahalli, Katherine G. Dailey, Ryan Acbay, Masataka Suzuki, George I. Balazs, Matthew K. Waldor

“…Previously, we demonstrated that systemic Escherichia coli infection in mice causes tissue damage in the liver. …”
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High-Performance Photocatalytic Multifunctional Material Based on Bi₄Ti₃O₁₂-Supported Ag and Ti₃C₂T_x for Organic D... by Kexi Zhang, Bingdong Yan, Xiaohong Wang, Yang Cao, Wanjun Hao, Jinchun Tu

“…In the specific performance studies, ascorbic acid and MB were used as the subjects of photochemical sensing and photodegradation properties, while <i>Escherichia coli</i> and <i>Staphylococcus aureus</i> were tested for antibacterial properties. …”
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Repeated positron emission tomography tracing neutrophil elastase in a porcine intensive-care sepsis model by Frida Wilske, Olof Eriksson, Rose-Marie Amini, Sergio Estrada, Helena Janols, Amina Khalil, Anders Larsson, Miklós Lipcsey, Sara Mangsbo, Jonathan Sigfridsson, Jan Sjölin, Paul Skorup, Anders Wall, Viola Wilson, Markus Castegren, Gunnar Antoni

“…Methods We used positron emission tomography (PET) combined with computed tomography (CT) and the selective and specific neutrophil elastase inhibitor PET-tracer [11C]GW457427 ([11C]NES), in an intensive care unit porcine Escherichia coli sepsis model with the primary aim to visualise the biodistribution of neutrophil elastase in the initial acute phase of the septic reaction. …”
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Creation of a recombinant Komagataella phaffii strain, a producer of proteinase K from Tritirachium album by A. B. Beklemishev, M. B. Pykhtina, Ya. M. Kulikov, T. N. Goryachkovskaya, D. V. Bochkov, S. V. Sergeeva, A. R. Vasileva, V. P. Romanov, D. S. Novikova, S. E. Peltek

“…The following methods were used: computational analysis of primary structure of the proteinase K gene, molecular biological methods (PCR, electrophoresis of DNA in an agarose gel, electrophoresis of proteins in an SDS polyacrylamide gel under denaturing conditions, spectrophotometry, and quantitative assays of protease activity), and genetic engineering techniques (cloning and selection of genes in bacterial cells Escherichia coli TOP10 and in the methylotrophic yeast K. phaffii K51). …”
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Effects of GABA Supplementation on Intestinal SIgA Secretion and Gut Microbiota in the Healthy and ETEC-Infected Weanling Piglets by Yuanyuan Zhao, Jing Wang, Hao Wang, Yonggang Huang, Ming Qi, Simeng Liao, Peng Bin, Yulong Yin

“…Pathogenic enterotoxigenic Escherichia coli (ETEC) has been considered a major cause of diarrhea which is a serious public health problem in humans and animals. …”
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