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Erythropoietin: from erythropoiesis to cardioprotection
Published 2010-08-01“…The identification of erythropoietin receptor in hematopoietic tissues, including the heart, as well as its marked cardioprotective effect during ischemia have led to the hypothesis that erythropoietin may be able to prevent anthracycline-induced cardiomyopathy. …”
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The Antioxidant Effect of Erythropoietin on Thalassemic Blood Cells
Published 2010-01-01“…Because of its stimulating effect on RBC production, erythropoietin (Epo) is used to treat anemia, for example, in patients on dialysis or on chemotherapy. …”
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THE ROLE OF ERYTHROPOIETIN IN TREATMENT OF ANEMIA IN CANCER PATIENTS
Published 2017-06-01“…This article analyzes the efficacy of recombinant erythropoietin — Epoetin-theta in the treatment of patients with NON — myeloid tumors and CRF (chronic renal failure) in cancer patients. …”
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Pharmacokinetics of PEGylated Recombinant Human Erythropoietin in Rats
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Polycythemia with Renal Cell Carcinoma and Normal Erythropoietin Level
Published 2019-01-01“…Though previously reported, the concomitant finding of an AAA with renal cell carcinoma with a normal erythropoietin levels is surprising. Given the surgical complications associated with concomitant conditions with renal cell carcinoma, further investigation into paraneoplastic syndromes secondary to renal cell carcinoma remains open to investigation.…”
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Erythropoietin, Forkhead Proteins, and Oxidative Injury: Biomarkers and Biology
Published 2009-01-01“…In particular, both the growth factor and cytokine erythropoietin (EPO), and members of the mammalian forkhead transcription factors of the O class (FoxOs), may offer the greatest promise for new treatment regimens, since these agents and the cellular pathways they oversee cover a range of critical functions that directly influence progenitor cell development, cell survival and degeneration, metabolism, immune function, and cancer cell invasion. …”
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Possible erythropoietin pharmacotherapeutic targets on painful diabetic neuropathy in rats
Published 2025-02-01Subjects: “…Erythropoietin…”
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Engineering synthetic signaling receptors to enable erythropoietin-free erythropoiesis
Published 2025-01-01“…Ex vivo manufacturing of red blood cells (RBCs) from universal donor cells offers a potential solution, yet the high cost of recombinant cytokines remains a barrier. Erythropoietin (EPO) signaling is crucial for RBC development, and EPO is among the most expensive media components. …”
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Correlation between ultrafiltration rate and hemoglobin level and erythropoietin response in hemodialysis patients
Published 2024-12-01Subjects: Get full text
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Optimization of amino acid-stabilized erythropoietin parenteral formulation: In vitro and in vivo assessment
Published 2016-03-01Subjects: “…erythropoietin (epo)…”
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Recombinant human erythropoietin, and myocardial and cerebral acute ischemia: implications for clinical use.
Published 2010-07-01“…Recombinant human erythropoietin has been used for more than two decades in clinical practice with promising results in the treatment of anemia associated with chronic renal insufficiency and in patients with cancer. …”
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Defective Slc7a7 transport reduces erythropoietin compromising erythropoiesis
Published 2025-01-01“…Further investigation indicated that defective erythropoiesis is linked to impaired erythropoietin production in the kidney and subsequent iron overload. …”
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Erythropoietin Dose and Mortality in Hemodialysis Patients: Marginal Structural Model to Examine Causality
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Nonhematopoietic Variants of Erythropoietin in Ischemic Stroke: Need for Step-Wise Proof-of-Concept Studies
Published 2010-01-01“…Neuroprotective, but not hematopoietic, variants of erythropoietin (EPO), such as Neuro-EPO, are promising candidates for treatment in the acute and subacute stroke phase. …”
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Effects of Low-Flux and High-Flux Dialysis Membranes on Erythropoietin Responsiveness in Hemodialysis Patients
Published 2022-01-01“…Inadequate data have described the efficiency of high-flux dialysis in promoting erythropoietin responsiveness in CKD patients in the Middle East. …”
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Impact of an Interleukin-1 Receptor Antagonist and Erythropoietin on Experimental Myocardial Ischemia/Reperfusion Injury
Published 2012-01-01“…We compared the impact of the interleukin-1 receptor antagonist Anakinra and erythropoietin on myocardial ischemia/reperfusion injury. …”
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Hemoglobin level and erythropoietin response in hemodialysis patients: what can we pay attention to?
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The Nasal Route as a Potential Pathway for Delivery of Erythropoietin in the Treatment of Acute Ischemic Stroke in Humans
Published 2009-01-01“…Using the intranasal delivery system, researchers have demonstrated neuroprotective effects in different animal models of stroke using erythropoietin (EPO) as a neuroprotector or other different types of EPO without erythropoiesis-stimulating activity. …”
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Visual-Evoked-Response-Supported Outcome of Intravitreal Erythropoietin in Management of Indirect Traumatic Optic Neuropathy
Published 2018-01-01“…Investigating the efficacy of intravitreal injection of erythropoietin (EPO) in managing indirect traumatic optic neuropathy (ITON) of different durations. …”
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