Formulation and characterization of CMPI nanoparticles for enhanced targeting of brain nicotinic receptors by positive allosteric modulator by Rahma Aly, Shoukath Sulthana, Robert Beaudoin, Ayman K. Hamouda, Santosh Aryal

“…A biodegradable and biocompatible, the US-FDA-approved, poly(l-lactic-co-glycolic) acid (PLGA) was used to engineer nanoparticles (NPs) to solubilize CMPI in its hydrophobic core in an aqueous environment using the nanoprecipitation with the drug loading content of 10 ± 1.2% by weight of NPs. …”
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Methylprednisolone substituted lipid nanoparticles deliver C3 transferase mRNA for combined treatment of spinal cord injury by Haoru Dong, Zongxing He, Shiyi Cai, Haiqiang Ma, Lili Su, Jianfeng Li, Huiying Yang, Rong Xie

“…In this study, we introduce an innovative approach by substituting cholesterol with MP to engineer a novel Lipid Nanoparticle (MP-LNP). This strategy aims to enhance the localization and concentration of MP at the injury site, thereby amplifying its therapeutic efficacy while mitigating systemic side effects. …”
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A novel TID + IDN controller tuned with coatis optimization algorithm under deregulated hybrid power system by Geetanjali Dei, Deepak Kumar Gupta, Binod Kumar Sahu, Mohit Bajaj, Vojtech Blazek, Lukas Prokop

“…Abstract Implementing a suitable load frequency controller to maintain the power balance equation for a multi-area system with many power generating units poses a challenge to a power system engineer. Incorporation of renewable energy sources along with non-renewable units is another challenge while maintaining the stability of the system. …”
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Atlas of multilineage stem cell differentiation reveals TMEM88 as a developmental regulator of blood pressure by Sophie Shen, Tessa Werner, Samuel W. Lukowski, Stacey Andersen, Yuliangzi Sun, Woo Jun Shim, Dalia Mizikovsky, Sakurako Kobayashi, Jennifer Outhwaite, Han Sheng Chiu, Xiaoli Chen, Gavin Chapman, Ella M. M. A. Martin, Di Xia, Duy Pham, Zezhuo Su, Daniel Kim, Pengyi Yang, Men Chee Tan, Enakshi Sinniah, Qiongyi Zhao, Sumedha Negi, Meredith A. Redd, Joseph E. Powell, Sally L. Dunwoodie, Patrick P. L. Tam, Mikael Bodén, Joshua W. K. Ho, Quan Nguyen, Nathan J. Palpant

“…Abstract Pluripotent stem cells provide a scalable approach to analyse molecular regulation of cell differentiation across developmental lineages. Here, we engineer barcoded induced pluripotent stem cells to generate an atlas of multilineage differentiation from pluripotency, encompassing an eight-day time course with modulation of WNT, BMP, and VEGF signalling pathways. …”
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Pengembangan Fast Render Objek Grafis Menggunakan Shader dan Non-Shader Berbasis WebGL dari Primitive Object untuk Membuat Raw Metaverse Material Objek Skybox 3D di Filkom UB by Imam Cholissodin, Eriq Muhammad Adams Jonemaro, Bayu Rahayudi, Willyan Eka Ksatria, Annisa Sukmawati, Muhammad Farid Muzayyani

“…Along with the development of computers today, any developer can engineer an object in the virtual world. The development problems that arise are usually related to the speedy rendering process of object engineering which in this study is making raw metaverse material in the form of adding basic 3D graphic objects (balls, cubes, torus, cylinders, and others) to the Skybox as part of augmented reality accompanied by effects of texture mapping, mirroring, coloring gradations, and animation control of object movements. …”
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Adoptive cell transfer of piezo-activated macrophage rescues immunosuppressed rodents from life-threating bacterial infections by Xiaoyi Liu, Wenxiu Xu, Junkun Feng, Ying Wang, Kai Li, Yi Chen, Wenjun Wang, Weiwei Zhao, Shaohua Ge, Jianhua Li

“…Our study thus highlights the potential application of catalytic nanoparticles as a promising alternative to conventional infection treatment to effectively modulate the innate immune responses and to engineer macrophages for immunotherapy purposes.…”
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DNA, Technology, and Florida Strawberries by Seonghee Lee, Young-Hee Noh, Sujeet Verma, Vance M. Whitaker

“… Are Florida strawberries genetically engineered? The answer is no. No genetically engineered strawberry has been commercialized anywhere in the world. …”
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A Gate Design Project. by Mugume, Charles

“…Therefore, in compliance with the above mentioned above, my project was based on the gate design at faculty of engineering, Kabale university.…”
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A Gate Design at Nyabikoni Campus Kabale University. by Gumisiriza, Benson

“…Kabale university faculty of engineering is an institution of higher learning education which prepares and enables its students to carry out projects in different groups. …”
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Vegetation restoration effectiveness with main factors in the Beijing-Tianjin sandstorm source region during 2000-2020, China. by Xingshuo Zhang, Jingfang Yuan, Xiaoman Liu, Cheng Zong

“…The Beijing-Tianjin Sandstorm Source Region (BTSSR), a region with significant vegetation degradation in China, has been subjected to ecological engineering intended to curb vegetation browning. Nevertheless, few studies have used multisource data to quantitatively evaluate the vegetation restoration effectiveness in the BTSSR, and the relationship between ecological engineering and vegetation restoration effectiveness in this region from statistical evidence has received little attention so far. …”
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How Likely Is a 100-Year Rainfall Event During the Next Ten Years? by Young Gu Her, William R. Lusher, Kati White Migliaccio

“… This 4-page fact sheet describes proper interpretation of rainfall event probabilities and recurrence intervals, particularly as they are used by engineers and water resources managers in the design and construction of hydraulic structures, such as dams, levees, and canals. …”
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Experimental investigation of the parameters of additively manufactured coaxial swirl injectors by Samir Vekilov, Volodymyr Lipovskyi, Roman Marchan, Artem Lohvynenko

“… Modern development of the intense competition on the market of Liquid Propellant Rocket Engines (LPRE) is mostly driven by occurrence of many private space companies, crowdfunding space projects, etc., which inevitably leads engineers to seeking of rational solutions with the aim of decreasing production costs along with increasing of the efficiency of the parts. …”
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Design of DC Motor Using Local Materials. by Ndyamuhaki, Bruce

“…This project showcased an innovative approach to motor design and construction, highlighting the potential for creative problem-solving and resourcefulness in engineering applications. The successful completion of this project provides a foundation for future improvement and retirement paving the way for potential applications in educational settings do it yourself enthusiasts, and sustainable engineering solutions…”
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How Are the Reservoirs in the ApalachicolaChattahoochee-Flint River Basin Managed? by Christopher J. Martinez

“…Many uses of the Apalachicola-Chattahoochee-Flint river basin depend on how the US Army Corp of Engineers operates dam releases from the reservoirs when managing lake levels and downstream river flows and water levels. …”
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Probabilistic assessment of passive earth pressures considering spatial variability of soil parameters and design factors by Jim Shiau, Tan Nguyen, Thinh Pham-Tran-Hung, Jun Sugawara

“…These findings provide practical tools for design engineers, supporting better decision-making and increasing confidence in design outcomes.…”
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