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NATURAL MUTAGENESIS AS A POSSIBLE CAUSAL FACTOR FOR OCCURRENCE OF OBLIGATE EMBRYONIC DIAPAUSE IN MAMMALS (A HYPOTHESIS)
Published 2014-12-01“…Available data of cytogenetics, embryology, evolutionary morphology, and evolutionary ecology allow to believe that the obligatory stage of embryonic diapause might occur in single individuals with indifferent taxonomic groups in consequence of chromosome mutation caused by alteration in the environment and affected the expression of genes controlling the timing of embryogenesis.…”
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42
Dopamine receptors and key elements of the neurotrophins (BDNF, CDNF) expression patterns during critical periods of ontogenesis in the brain structures of mice with autism-like be...
Published 2024-07-01“…At the same time, the increase in p75NTR receptor gene expression observed on the 14th day of embryogenesis, crucial for hippocampus and frontal cortex development, may have direct relevance to the manifestation of early autism.…”
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43
STAT3-Inducible Mouse ESCs: A Model to Study the Role of STAT3 in ESC Maintenance and Lineage Differentiation
Published 2018-01-01“…However, there is still lack of direct evidence on STAT3 functions in ESCs and embryogenesis because constitutive STAT3 knockout (KO) mouse is embryonic lethal at E6.5–E7.5, prior to potential functional role in early development can be assessed. …”
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44
The Life of Embryon According to Thomas Aquinas
Published 2013-07-01“…He exposes in six stage of embryogenesis, which we can discover in his writings, the identity of the embryo in all process of his development. …”
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45
Targeting Signaling Pathways in Cancer Stem Cells for Cancer Treatment
Published 2017-01-01“…The Wnt, Hedgehog, and Notch pathways are inherent signaling pathways in normal embryogenesis, development, and hemostasis. However, dysfunctions of these pathways are evident in multiple tumor types and malignancies. …”
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46
Gastrointestinal myofibroblasts: role in regulation of physiological activity and reparation of gastro-intestinal tract
Published 2010-06-01“…To analyze organ-specific features of gastrointestinal myofibroblasts, functional properties, role in embryogenesis and healing of ulcers of gastro-intestinal tract (GIT).Original positions. …”
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47
A Bird’s-Eye Overview of Leptin and Female Reproduction —with Mammalian Comparisons
Published 2025-02-01“…Leptin, a key regulator of reproductive physiology, influences various processes in vertebrates, including oocyte proliferation, embryogenesis, the onset of puberty, ovarian function, and follicle development. …”
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48
The Mitochondrial Disulfide Relay System: Roles in Oxidative Protein Folding and Beyond
Published 2013-01-01“…We proceed by discussing recently described functions of Mia40 in the hypoxia response and of ALR in influencing mitochondrial morphology and its importance for tissue development and embryogenesis. We also include a discussion of the still mysterious function of Erv1/ALR in liver regeneration.…”
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49
Genetic Transformation of Common Bean (Phaseolus vulgaris L.) with the Gus Color Marker, the Bar Herbicide Resistance, and the Barley (Hordeum vulgare) HVA1 Drought Tolerance Genes
Published 2012-01-01“…Transgenes included gus color marker which visually confirmed transgenic events, the bar herbicide resistance selectable marker used for in vitro selection of transgenic cultures and which confirmed Liberty herbicide resistant plants, and the barley (Hordeum vulgare) late embryogenesis abundant protein (HVA1) which conferred drought tolerance with a corresponding increase in root length of transgenic plants. …”
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50
PAX8 Distinguishes Diffuse Large B-Cell Lymphoma Mimicking Sarcoma
Published 2017-01-01“…PAX8 is important for embryogenesis of the thyroid, Müllerian system, and upper urinary/renal tract, and expression of PAX8 has been described in carcinomas from each of these sites. …”
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51
Inherited glycosylphosphatidylinositol deficiency disorders: a new group of inherited metabolic disorders
Published 2024-12-01“…These glycosylphosphatidylinositol-anchored proteins are an important part of receptors, function as hydrolytic enzymes, and play a crucial role in molecules adhesion, immune response, embryogenesis and neurogenesis. Patients present a variety of symptoms including developmental delay with intellectual disability, abnormalities of the central nervous, skeletal, circulatory, gastrointestinal, and urinary systems, facial dysmorphia as well as hearing and visual impairment. …”
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52
Drought Tolerance in Wheat
Published 2013-01-01“…In wheat, there are several genes which are responsible for drought stress tolerance and produce different types of enzymes and proteins for instance, late embryogenesis abundant (lea), responsive to abscisic acid (Rab), rubisco, helicase, proline, glutathione-S-transferase (GST), and carbohydrates during drought stress. …”
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53
Advances in PIWI-piRNA function in female reproduction in mammals
Published 2024-11-01“…Recent discoveries of crucial PIWI-piRNA functions in oogenesis and embryogenesis in golden hamsters suggest an indispensable role in female fertility that has been obscured in the predominant mouse model of PIWI-piRNA pathway regulation. …”
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54
Wnt5a Signaling in Normal and Cancer Stem Cells
Published 2017-01-01“…In this article, we review recent findings regarding the molecular mechanisms and roles of Wnt5a signaling in stem cells in embryogenesis and in the normal or neoplastic breast or ovary, highlighting that Wnt5a may have different effects on target cells depending on the surface receptors expressed by the target cell.…”
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55
Long Noncoding RNA Regulation of Pluripotency
Published 2016-01-01“…As such, human Embryonic Stem Cells (hESCs) and human induced Pluripotent Stem Cells (hiPSCs) provide a unique opportunity for studying the earliest steps of human embryogenesis and, at the same time, are of great therapeutic interest. …”
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56
Role of microglia in the pathogenesis of multiple sclerosis and links to immunomodulatory therapy
Published 2023-10-01“…Microglia are cells of the central nervous system that develop from yolk sac macrophages during embryogenesis. These cells perform important functions in the development of the central nervous system and the retina, in the formation of synapses, protect against pathogens, and are involved in the removal of damaged structures. …”
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Cellular Response upon Stress: p57 Contribution to the Final Outcome
Published 2015-01-01“…Progression through the cell cycle is one of the most important decisions during the life of a cell and several kinds of stress are able to influence this choice. p57 is a cyclin-dependent kinase inhibitor belonging to the CIP/KIP family and is a well-known regulator of the cell cycle during embryogenesis and tissue differentiation. p57 loss has been reported in a variety of cancers and great effort has been spent during the past years studying the mechanisms of p57 regulation and the effects of p57 reexpression on tumor growth. …”
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Disorders in brassinosteroids signal transduction triggers the profound molecular alterations in the crown tissue of barley under drought.
Published 2025-01-01“…Importantly, we detected the converging upregulation of several proteins and encoding genes under drought, including late embryogenesis abundant proteins and chaperones; they represent a promising target for cereals' improvement. …”
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Electrochemical impedance spectroscopy as a micropropagation monitoring tool for plants: A case study of tamarillo Solanum betaceum callus
Published 2025-02-01“…Summary: Tamarillo is an economically important species that has been extensively studied in terms of in vitro morphogenesis and micropropagation techniques, including somatic embryogenesis. Callus cultures are used to characterize plant growth and differentiation as well as the production of secondary metabolites. …”
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The Role of Epigenetic in Dental and Oral Regenerative Medicine by Different Types of Dental Stem Cells: A Comprehensive Overview
Published 2022-01-01“…Epigenetics describes changes in gene expression rather than changes in DNA and broadly happens in bone homeostasis, embryogenesis, stem cell fate, and disease development. …”
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