Development and experimental validation of a machine learning model for the prediction of new antimalarials by Mukul Kore, Dimple Acharya, Lakshya Sharma, Shruthi Sridhar Vembar, Sandeep Sundriyal

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Matched pairs demonstrate robustness against inter-assay variability by Jochem Nelen, Horacio Pérez-Sánchez, Hans De Winter, Dries Van Rompaey

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Induction of territorial dominance and subordination behaviors in laboratory mice by Dorian Battivelli, Lucas Boldrini, Mohit Jaiswal, Pradnya Patil, Sofia Torchia, Elizabeth Engelen, Luca Spagnoletti, Sarah Kaspar, Cornelius T. Gross

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Structural basis of Spliced Leader RNA recognition by the Trypanosoma brucei cap-binding complex by Harald Bernhard, Hana Petržílková, Barbora Popelářová, Kamil Ziemkiewicz, Karolina Bartosik, Marcin Warmiński, Laura Tengo, Henri Gröger, Luciano G. Dolce, Cameron D. Mackereth, Ronald Micura, Jacek Jemielity, Eva Kowalinski

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Generation of a genetically encoded voltage indicator MARINA reporter human iPS cell line using Cas9 (VULSCi002-A-2) by Aistė Petruškevičiūtė, Ugnė Šimuliūnaitė, Catalina M. Polanco, Barbara Rojas, Simonas Kuras, Beatričė Valatkaitė-Rakštienė, Rimvydas Norvilas, Akshay Kumar Vijaya, Patricia Muñoz, Urtė Neniškytė, Artūras Jakubauskas, Aurelijus Burokas, Ivan Nalvarte, Jose Inzunza, Daniel Naumovas, Mindaugas Stoškus, Laimonas Griškevičius, Daiva Baltriukienė, Jonathan Arias

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Metabolic activities are selective modulators for individual segmentation clock processes by Mitsuhiro Matsuda, Jorge Lázaro, Miki Ebisuya

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Patient‐derived acellular ascites fluid affects drug responses in ovarian cancer cell lines through the activation of key signalling pathways by Katharina Bischof, Andrea Cremaschi, Lena Eroukhmanoff, Johannes Landskron, Lise‐Lotte Flage‐Larsen, Alexandra Gade, Line Bjørge, Alfonso Urbanucci, Kjetil Taskén

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Sequence analysis of tyrosine recombinases allows annotation of mobile genetic elements in prokaryotic genomes by Georgy Smyshlyaev, Alex Bateman, Orsolya Barabas

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Salmonella infection impacts host proteome thermal stability by Marlène S. Birk, Philipp Walch, Tarik Baykara, Stephanie Sefried, Jan Amelang, Elena Buerova, Ingrid Breuer, Jörg Vervoorts, Athanasios Typas, Mikhail M. Savitski, André Mateus, Joel Selkrig

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ANALISIS LC-MS/MS SENYAWA METABOLITE EKSTRAK DAUN PUTAT (Planchonia valida) DAN PREDIKSI POTENSINYA SEBAGAI KANDIDAT OBAT ANTIKANKER by Tribuana Tungga Dewi, Anisa Bela, Satria Prabawa, Madyawati Latief, Indra Lasmana Tarigan

“…Metode yang digunakan yaitu menganalisis senyawa yang diperoleh dari hasil LC-MS, menskrining senyawa menggunakan website pChEMBL dan ChemSpiders. Dan menggunakan webserver pChEMBL untuk mengetahui bioaktifitas dari senyawa-senyawa tersebut. …”
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An interaction network of inner centriole proteins organised by POC1A-POC1B heterodimer crosslinks ensures centriolar integrity by Cornelia Sala, Martin Würtz, Enrico Salvatore Atorino, Annett Neuner, Patrick Partscht, Thomas Hoffmann, Sebastian Eustermann, Elmar Schiebel

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Harnessing the Power of Machine Learning Guided Discovery of NLRP3 Inhibitors Towards the Effective Treatment of Rheumatoid Arthritis by Sidra Ilyas, Abdul Manan, Chanyoon Park, Hee-Geun Jo, Donghun Lee

“…Out of all docked compounds, the two most promising compounds (ChEMBL5289544 and ChEMBL5219789) with binding scores of −7.5 and −8.2 kcal/mol were further investigated by MD to evaluate their stability and dynamic behavior within the binding site. …”
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Structural insights into distinct mechanisms of RNA polymerase II and III recruitment to snRNA promoters by Syed Zawar Shah, Thomas N. Perry, Andrea Graziadei, Valentina Cecatiello, Thangavelu Kaliyappan, Agata D. Misiaszek, Christoph W. Müller, Ewan P. Ramsay, Alessandro Vannini

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Genome sequence of the Mediterranean red coral Corallium rubrum by Philippe Ganot, Tobias Rausch, Markus Hsi-Yang Fritz, Didier Zoccola, Xin Wang, Manuel Aranda, Vladimir Benes, Denis Allemand, Sylvie Tambutté

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Alleviating batch effects in cell type deconvolution with SCCAF-D by Shuo Feng, Liangfeng Huang, Anna Vathrakokoili Pournara, Ziliang Huang, Xinlu Yang, Yongjian Zhang, Alvis Brazma, Ming Shi, Irene Papatheodorou, Zhichao Miao

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A new knockin mouse carrying the E364X patient mutation for CDKL5 deficiency disorder: neurological, behavioral and molecular profiling by C. Quadalti, M. Sannia, N.E. Humphreys, V.A. Baldassarro, A. Gurgone, M. Ascolani, L. Zanella, L. Giardino, C.T. Gross, S. Croci, I. Meloni, M. Giustetto, A. Renieri, L. Lorenzini, L. Calzà

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Long-range organization of intestinal 2D-crypts using exogenous Wnt3a micropatterning by Enara Larrañaga, Miquel Marin-Riera, Aina Abad-Lázaro, David Bartolomé-Català, Aitor Otero, Vanesa Fernández-Majada, Eduard Batlle, James Sharpe, Samuel Ojosnegros, Jordi Comelles, Elena Martinez

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Arrested Coalescence: A Tool to Explore Tissue Rheology by Sotiris Samatas, Martí Planasdemunt-Hospital, David Oriola

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L’enfant de Mezmaiskaya (Caucase) examiné dans une double perspective paléogénétique et paléoanthropologique by Véronique Barriel, Anne-Marie Tillier

“…The palaeogenetic interpretation is examined in the present article based on data available for modern humans (Anderson et al. 1981; HvrBase; http://www.hvrbase.de) and for three Middle Palaeolithic fossils from Germany (Feildhofer 1 and 2 ; Krings et al. 1997; Krings et al. 1999; Schmitz et al. 2002) and Croatia (Vindija-75-G3/h-203; Krings et al. 2000), which are attributed to the Neanderthal line and those of Pan paniscus and the four sub-species of Pan troglodytes (EMBL and GenBank). The question of the phylogenetic status of the Mezmaiskaya child is examined using both molecular analysis and anthropological arguments.…”
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Longitudinal omics data and preclinical treatment suggest the proteasome inhibitor carfilzomib as therapy for ibrutinib-resistant CLL by Lavinia Arseni, Gianluca Sigismondo, Haniyeh Yazdanparast, Johanne U. Hermansen, Norman Mack, Sibylle Ohl, Verena Kalter, Murat Iskar, Mathias Kalxdorf, Dennis Friedel, Mandy Rettel, Yashna Paul, Ingo Ringshausen, Eric Eldering, Julie Dubois, Arnon P. Kater, Marc Zapatka, Philipp M. Roessner, Eugen Tausch, Stephan Stilgenbauer, Sascha Dietrich, Mikhail M. Savitski, Sigrid S. Skånland, Jeroen Krijgsveld, Peter Lichter, Martina Seiffert

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