SIMULAÇÃO E ANÁLISE ECONÔMICA DA TRANSESTERIFICAÇÃO DA TRIACETINA VIA CATÁLISE ÁCIDA HETEROGÊNEA COM FOCO NO TIPO DE REATOR E NAS CONDIÇÕES OPERACIONAIS by Paula Geovana Gomes, Rafael Luiz Temóteo, Wagner Luís Silva Faria, Fábio Ávila Rodrigues, Deusanilde de Jesus Silva

“…Nas simulações realizadas, comparou-se o desempenho dos reatores CSTR e PFR a 150°C e 12 bar com o desempenho dos mesmos em condições de operação mais brandas, em torno de 60°C e 1 bar. Nesse último caso, analisou-se o efeito da implantação de uma corrente de reciclo em cada reator. …”
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Analysis of Fractional Order Mathematical Model of Hematopoietic Stem Cell Gene-Based Therapy by Mohammad Imam Utoyo, Windarto, Aminatus Sa’adah

“…Based on the model analysis, we obtained three equilibriums, namely, free virus equilibrium (FVE) E0, CTL-Exhaustion Equilibrium (CEE) E1, and control immune equilibrium (CIE) E2. Besides, we obtained Basic Reproduction Number R0 that determines the existence and stability of the equilibriums. …”
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Extraction of Least-Dispersive Ultrasonic Guided Wave Mode in Rail Track Based on Floquet-Bloch Theory by Maodan Yuan, Peter W. Tse, Weiming Xuan, Wenjin Xu

“…In this paper, a numerical study on the guided wave propagation was carried out on a standard rail with 56E1 profile. Firstly, Floquet-Bloch theory was applied to obtain the dispersion curves of guided wave in a rail. …”
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Accumulation of Deficits as a Proxy Measure of Aging by Arnold B. Mitnitski, Alexander J. Mogilner, Kenneth Rockwood

“…The accumulation of deficits is as an example of a macroscopic variable, i.e., one that reflects general properties of aging at the level of the whole organism rather than any given functional deficiency. …”
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Bioactive milk-derived nutrient MFG-E8 ameliorates skeletal muscle atrophy induced by mitochondria damage in aging rats via activating the MAPK/ERK signaling pathway by Kaifang Guan, Xiaolin Liu, Weihong Lu, Yuhao Mao, Yirong Mao, Ying Ma, Rongchu Wang, Qiming Li

“…Flow cytometry and quantitative real-time PCR proved that MFG-E8 promoted cell proliferation by upregulating mRNA expression of cyclin D1, cyclin E1, CDK, and downregulating mRNA expression of p21 and p27, thereby increasing the S and G2/M phase and decreasing the G0/G1 phase. …”
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Facile heterocyclic synthesis and antimicrobial activity of polysubstituted and condensed pyrazolopyranopyrimidine and pyrazolopyranotriazine derivatives by Hafez Hend N., Alshammari Abdulrahman G., El-Gazzar Abdel-Rhman B. A.

“…Condensation of 2 with aromatic aldehyde gave the corresponding Schiff bases 11a,b, the oxidative cyclization of the hydrazone with appropriate oxidant afforded 11-(4- fluorophenyl))- 2-(4-substituted phenyl)-10-methyl-8,11-dihydropyrazolo-[ 4’,3’:5,6]pyrano[3,2-e][1,2,4]triazolo[1,5-c]pyrimidines (12a,b). Structures of the synthesized compounds were confirmed by spectral data and elemental analysis. …”
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Cytochrome P450 Metabolism of Betel Quid-Derived Compounds: Implications for the Development of Prevention Strategies for Oral and Pharyngeal Cancers by Che-Yi Lin, Tien-Szu Pan, Chun-Chan Ting, Shih-Shin Liang, Shu-Hung Huang, Hsiu-Yueh Liu, Edward Cheng-Chuan Ko, Chung-Wei Wu, Jen-Yang Tang, Ping-Ho Chen

“…In clinical applications, we focus on cancers of the oral cavity and pharynx and OPMDs associated with CYP gene polymorphisms, including CYP1A1, CYP2A6, CYP2E1, and CYP26B1. Our discussion of CYP polymorphisms provides insight into the importance of screening tests in OPMDs patients for the prevention of oral and pharyngeal cancers. …”
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Detection by Single-Cell RNA Sequencing of Virally Mediated Skin Diseases by Linda Zhou, Thomas H. Leung

“…In rubella virus–infected cells, we discover macrophage-specific evolution of the rubella virus E1 capsid protein. Finally, we interrogate skin biopsies from many established nonvirally mediated inflammatory skin diseases and do not find consistent evidence of viral infection in any condition. …”
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Autism-Like Behavior and Epigenetic Changes Associated with Autism as Consequences of In Utero Exposure to Environmental Pollutants in a Mouse Model by Denise S. Hill, Robert Cabrera, Deeann Wallis Schultz, Huiping Zhu, Wei Lu, Richard H. Finnell, Bogdan J. Wlodarczyk

“…Mouse dams were treated with cadmium, lead, arsenate, manganese, and mercury via drinking water from gestational days (E) 1–10. Valproic acid (VPA) injected intraperitoneally once on (E) 8.5 served as a positive control. …”
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Cytoskeletal Vimentin Directs Cell‐Cell Transmission of Hepatitis C Virus by Yifan Xing, Zeyu Wen, Jie Mei, Xinyi Huang, Shuangshuang Zhao, Jin Zhong, Yaming Jiu

“…Through mutual co‐immunoprecipitation screening, we identified that the N‐terminal 1–95 amino acids of vimentin exclusively interact with the HCV envelope protein E1. Introducing either full‐length or head region of vimentin is capable of restoring the cell–cell transmission deficiency in vimentin‐knockout cells. …”
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The Effect of Cyclooxygenase Inhibition on Tendon-Bone Healing in an In Vitro Coculture Model by Tim Schwarting, Sebastian Pretzsch, Florian Debus, Steffen Ruchholtz, Philipp Lechler

“…We measured the dose-dependent effects of ibuprofen and parecoxib on the viability of lipopolysaccharide- (LPS-) stimulated and unstimulated mouse MC3T3-E1 and 3T3 cells, the influence on gene expression at the osteoblast, interface, and fibroblast regions measured by quantitative PCR, and cellular outgrowth assessed on histological sections. …”
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Identification and pharmacokinetics of saponins in Rhizoma Anemarrhenae after oral administration to rats by HPLC-Q-TOF/MS and HPLC-MS/MS by Wang Hai-Qiao, Lan Fen, Zhang Yi-Han, Xia Jin-Er, Gong Xiao-Mei, Liu Min

“…These were neomangiferin, mangiferin, timosaponin E1, timosaponin E, timosaponin B-II, timosaponin B-III, timosaponin A-III and timosaponin A-I. …”
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Observations of Microlensed Images with Dual-field Interferometry: On-sky Demonstration and Prospects by Przemek Mróz, Subo Dong, Antoine Mérand, Jinyi Shangguan, Julien Woillez, Andrew Gould, Andrzej Udalski, Frank Eisenhauer, Yoon-Hyun Ryu, Zexuan Wu, Zhuokai Liu, Hongjing Yang, —, Guillaume Bourdarot, Denis Defrère, Antonia Drescher, Maximilian Fabricius, Paulo Garcia, Reinhard Genzel, Stefan Gillessen, Sebastian F. Hönig, Laura Kreidberg, Jean-Baptiste Le Bouquin, Dieter Lutz, Florentin Millour, Thomas Ott, Thibaut Paumard, Jonas Sauter, T. Taro Shimizu, Christian Straubmeier, Matthias Subroweit, Felix Widmann, (The GRAVITY+ Collaboration), Michał K. Szymański, Igor Soszyński, Paweł Pietrukowicz, Szymon Kozłowski, Radosław Poleski, Jan Skowron, Krzysztof Ulaczyk, Mariusz Gromadzki, Krzysztof Rybicki, Patryk Iwanek, Marcin Wrona, Mateusz J. Mróz, (The OGLE Collaboration), Michael D. Albrow, Sun-Ju Chung, Cheongho Han, Kyu-Ha Hwang, Youn Kil Jung, In-Gu Shin, Yossi Shvartzvald, Jennifer C. Yee, Weicheng Zang, Sang-Mok Cha, Dong-Jin Kim, Seung-Lee Kim, Chung-Uk Lee, Dong-Joo Lee, Yongseok Lee, Byeong-Gon Park, Richard W. Pogge, (KMTNet Collaboration)

“…We measure the angular Einstein radius of the lens with subpercent precision, θ _E  = 1.280 ± 0.009 mas. Combined with the microlensing parallax detected from the event light curve, the mass and distance to the lens are found to be 0.472 ± 0.012 M _⊙ and 1.81  ±  0.05 kpc, respectively. …”
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Modeling HIV outbreaks: The male to female prevalence ratio in the core population by Brandy Rapatski, James Yorke

“…We investigate two very different scenarios, one in which there are two times as many core men as core women ($E=2$) and the other in which core men equal core women ($E=1$). In the first case, the HIV epidemic grows at a much faster rate. …”
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In Vitro Osteogenic Properties of Two Dental Implant Surfaces by Marta Monjo, Christiane Petzold, Joana Maria Ramis, Staale Petter Lyngstadaas, Jan Eirik Ellingsen

“…The aim of the study was to perform a full characterization of the effect of two commercial titanium (Ti) surfaces, OsseoSpeed and TiOblast, on the behaviour of mouse preosteoblast MC3T3-E1 cells. The effect of these Ti surfaces was compared with tissue culture plastic (TCP). …”
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RESÚMENES DE TESIS DOCTORALES

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Maja Jović: A very Moroccan month by Maja Jović

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Brasília(s) by Haydée Caruso, Cyntia Cristina de Carvalho e Silva

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Protocol for cell image-based spatiotemporal proteomics in budding yeast by Athanasios Litsios, Myra Paz David Masinas, Helena Friesen, Charles Boone, Brenda J. Andrews

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