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441
Design and Synthesis of Two Oxazine Derivatives Using Several Strategies
Published 2014-01-01“…Therefore, in this study, two oxazine derivatives (2-chloro-3-{{2-[-(3-chloro-2-oxo-cyclobutyl)-(2,3-dimethoxy-9,10-dihydrostrychnid-10-yl)-amino]-ethyl}-[1,5-dimethyl-4-(1H-naphtho[1,2-e][1,3-oxazin-2-yl)-2-phenyl-2,3-dihydro-1H-pyrazol-3-yl]-amino}-cyclobutanone and 2-chloro-3-{{2-[(3-chloro-2-oxo-cyclobutyl)-(1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl)-amino]-ethyl}-[1,5-dimethyl-4-(1H-naphtho[1,2-e][1,3]oxazin-2-yl)-2-phenyl-2,3-dihydro-1H-pyrazol-3-yl]-amino}-cyclobutanone) were synthesized using several strategies. …”
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442
Experimental Validation of Antiobesogenic and Osteoprotective Efficacy of Ginsenoside CK via Targeting Lipid and Atherosclerosis Pathways
Published 2024-12-01“…These hypotheses were validated by harvesting and cultivating 3T3-L1 and MC3T3-E1 in adipogenic and osteogenic media with varying concentrations of CK. …”
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443
Acupuncture and Kinesitherapy Improve Physical Activity More than Kinesitherapy Alone in Patients with Acute Decompensated Chronic Heart Failure with Reduced Ejection Fraction Who...
Published 2025-01-01“…After 5 days, 80%, 50%, and 10% achieved an A test score of 30 or higher, demonstrating functional independence, (<i>p</i> < 0.01) in the E2, E1, and C groups, respectively. At hospital discharge, the E2 group showed significantly better walking endurance compared to the E1 and C groups (<i>p</i> < 0.001). …”
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444
Exploring the Anti-Osteoporotic Effects of <i>n</i>-Hexane Fraction from <i>Cotoneaster wilsonii</i> Nakai: Activation of Runx2 and Osteoblast Differentiation In Vivo
Published 2025-01-01“…Methods and Results: The alkaline phosphatase (ALP) activity of <i>C. wilsonii</i> extracts and fractions was evaluated in MC3T3-E1 pre-osteoblasts, and the <i>n</i>-hexane fraction (CWH) showed the best properties for ALP activity. …”
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445
بررسی رابطه واحدهای زمینشناسی با شدت فرسایش به کمک دو مدل با ساختار متفاوت (مطالعه موردی: حوزه آبخیز اخترآباد)...
Published 2023-09-01“…بررسی سازندها در مدل فارگاس نشان داده است که واحدهای سنگ چینهای E1t1, E1t2, E2ig3, Q2f, Qt1 و Qt2 دارای شدت فرسایش بسیار شدید بودهاند؛ درحالیکه در مدل پسیاک اصلاح شده واحدهای سنگ چینهای E1t1 ,Qt1 و Qt2 دارای شدت فرسایش زیاد هستند که دلیل آن فرسایشپذیری سازندها است، همچنین واحدهای سنگ چینهای E1t2 و Q2t دارای شدت فرسایش خیلی زیاد هستند که دلیل آن علاوه بر فرسایشپذیر بودن سازندها، تراکم بالای زهکشی در آنها نیز هست.…”
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446
Activation of osteoblast ferroptosis by risperidone accelerates bone loss in mice models of schizophrenia
Published 2025-01-01“…In addition, ALP staining, ARS staining, and WB were performed to reveal the role of RIS in osteogenic differentiation of MC3T3-E1 and BMSCs cells. Results RIS treatment facilitates bone loss in schizophrenia mice and inhibit osteogenic differentiation of MC3T3-E1 and BMSCs cells. …”
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447
Fréchet algebras generated by certain of their elements
Published 1995-01-01“…We consider F-algebras A that are generated by elements of the form z, (z−λ1e)−1,…,(z−λNe)−1, where e is the identity. If A has no topclogical divisors of zero we show that A is isomorphic to H(Ω), where Ω is finitely connected region. …”
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448
A historical perspective on the multifunctional outer membrane channel protein TolC in Escherichia coli
Published 2025-01-01“…It also acts as a receptor for specific bacteriophages and the colicin E1 toxin. This review highlights key discoveries over the past six decades and emphasizes the remaining gaps in understanding how TolC contributes to physiological functions in E. coli.…”
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449
Potencial antioxidante dos ésteres de pequi (Caryocar coriaceum) na criopreservação de sêmen bovino e na fertilização in vitro
Published 2025-02-01“…Os resultados mostraram que as concentrações de 1,0 e 1,5 mL/L de ésteres de pequi reduziram significativamente a concentração de malondialdeído no sêmen criopreservado. …”
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450
Effects of Different Vegetation Restoration Measures on the Disintegration Characteristics of Eroded Degraded Land of Pinus massoniana in Red Soil Region
Published 2024-12-01“…Compared with CK, the soil disintegration coefficient of E1, E2 and E3 measures decreased by 16.3%, 52.5% and 67.2%, respectively. …”
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451
Isoniazid and Rifampicin Produce Hepatic Fibrosis through an Oxidative Stress-Dependent Mechanism
Published 2020-01-01“…These were associated with concurrent apoptosis of the hepatocytes, increase in hepatic cytochrome P450 2E1 (CYP2E1), NADPH oxidase (NOX) activity, and development of hepatic oxidative stress. …”
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452
Tunable High-Frequency Acoustoelectric Current Oscillations in Fluorine-Doped Single-Walled Carbon Nanotubes
Published 2024-01-01“…The study also investigated the influence of various FSWCNT parameters such as the overlapping integrals (Δs and Δz), ac-field E1, and carrier concentration noon the behaviour of the ADC. …”
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453
High interindividual variability of indoxyl sulfate production identified by an oral tryptophan challenge test
Published 2025-01-01“…There was no significant difference in baseline characteristics or CYP2E1 and SULT1A1-SNP genotyping distributions between the two IS-producing phenotypes. …”
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454
Crystal structure of (E)-7-hydroxy-2-((6-methoxypyridin-2-yl)methylene)-3,4-dihydronaphthalen-1(2H)-one, C17H15NO3
Published 2021-09-01“…C17H15NO3, triclinic, P1‾$P‾{1}$ (no. 2), a = 7.5016(4) Å, b = 13.6750(8) Å, c = 14.8557(9) Å, α = 115.469(6)°, β = 91.726(5)°, γ = 97.325(5)°, V = 1358.48(15) Å3, Z = 4, Rgt(F) = 0.0442, wRref(F2) = 0.1095, T = 100 K.…”
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455
Crystal structure of (E)-7-methoxy-2-((6-methoxypyridin-2-yl)methylene)-tetralone, C18H17NO3
Published 2021-09-01“…C18H17NO3, triclinic, P1‾$P‾{1}$ (no. 2), a = 4.0929(4) Å, b = 12.9527(11) Å, c = 14.4228(12) Å, α = 70.171(8)°, β = 87.229(8)°, γ = 87.567(8)°, V = 718.16(12) Å3, Z = 2, Rgt(F) = 0.0549, wRref(F2) = 0.1526, T = 99.9(3) K.…”
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456
The crystal structure of diaqua-bis(2-(3-(1H-pyrazol-4-yl)-1H-1,2,4-triazol-5-yl)pyridine-κ2 N:N′)-bis(3,5-dicarboxybenzoato-κ1 O)cobalt(II), C38H30CoN12O14
Published 2021-09-01“…C38H30CoN12O14, triclinic, P1‾ $P‾{1}$ (no. 2), a = 6.9503(3) Å, b = 7.0244(4) Å, c = 20.1182(9) Å, α = 92.261(4)°, β = 95.206(4)°, γ = 104.600(4)°, V = 944.59(8) Å3, Z = 1, R gt(F) = 0.0408, wR ref(F 2) = 0.0910, T = 287 K.…”
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457
A Note on the Primitive Roots and the Golomb Conjecture
Published 2021-01-01“…Then, for any positive integer n with p1/2+ɛ≤n<p, there must exist two primitive roots α and β modulo p with 1<α,β≤n−1 such that the equation n=α+β holds, where 0<ɛ<1/2 is a fixed positive number. In other words, n can be expressed as the exact sum of two primitive roots modulo p.…”
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458
The crystal structure of N,N′-(Disulfanediyldi-2,1-phenylene)di(6′-methylpyridine)-2-carboxamide, C26H22N4O2S2
Published 2021-09-01“…C26H22N4O2S2, triclinic, P1‾$P‾{1}$ (no. 2), a = 7.9495(7) Å, b = 11.2494(12) Å, c = 13.7829(13) Å, α = 81.433(2)°, β = 76.536(1)°, γ = 82.641(2)°, V = 1179.7(2) Å3, Z = 2, Rgt(F) = 0.0727, wRref(F2) = 0.2189, T = 298(2) K.…”
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459
Redetermination of the crystal structure of (2E,4Z,13E,15Z)-3,5,14,16-tetramethyl-2,6,13,17-tetraazatricyclo[16.4.0.07,12]docosa-1(22),2,4,7,9,11,13,15,18,20-decaene, C22H24N4
Published 2021-09-01“…C22H24N4, triclinic, P1‾ $P‾{1}$ (no. 2), a = 9.217(4) Å, b = 9.774(4) Å, c = 10.843(4) Å, α = 96.770(2)°, β = 101.791(5)°, γ = 105.873(3)°, V = 903.9(6) Å3, Z = 2, R gt(F) = 0.0391, wR ref(F 2) = 0.1069, T = 93(2) K.…”
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460
The crystal structure of cis-diaqua-bis (N-butyl-N-(pyridin-2-yl)pyridin-2-amine-κ2N,N′)cobalt(II)] dichloride trihydrate, C28H44Cl2N6O5Co
Published 2021-09-01“…C28H44Cl2N6O5Co, triclinic, P1‾$P‾{1}$ (no. 2), a = 11.20(2) Å, b = 12.70(3) Å, c = 12.80(4) Å, α = 100.30(12)°, β = 103.18(9)°, γ = 106.77(6)°, V = 1638(8) Å3, Z = 2, Rgt(F) = 0.0372, wRref(F2) = 0.0890, T = 100 K.…”
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