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161
Gene regulatory patterning codes in early cell fate specification of the C. elegans embryo
Published 2024-01-01“…Moreover, we find that genes that segment the entire embryo in Drosophila have orthologs in C. elegans that exhibit sub-lineage-specific expression. …”
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162
Diversity and functions of fungal VOCs with special reference to the multiple bioactivities of the mushroom alcohol
Published 2025-01-01“…When Drosophila was cultivated in an atmosphere shared with VOC mixtures released from growing cultures of several medically important fungi, including Aspergillus fumigatus, toxicity was observed. …”
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163
Evaluating Dose- and Time-Dependent Effects of Vitamin C Treatment on a Parkinson’s Disease Fly Model
Published 2019-01-01“…With the purpose of further investigating the efficiency of vitamin C in PD treatment, we used dUCH knockdown Drosophila model to examine the dose- and time-dependent effects of vitamin C on PD-like phenotypes. …”
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164
Oxidative stress caused by 3-monochloro-1,2-propanediol provokes intestinal stem cell hyperproliferation and the protective role of quercetin
Published 2025-02-01“…Here, we employed the adult intestine of Drosophila melanogaster, a notable invertebrate model organism, to investigate the intestinal toxicity of 3-MCPD and its underlying mechanisms. …”
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165
Glia control experience-dependent plasticity in an olfactory critical period
Published 2025-01-01“…These data demonstrate experience-dependent pruning of synapses and argue that Drosophila olfactory circuitry is a powerful model for defining the function of glia in critical period plasticity.…”
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166
Erasing Synapses in Sleep: Is It Time to Be SHY?
Published 2012-01-01“…SHY has also received important experimental support from recent studies in Drosophila melanogaster. There remain, however, a number of unanswered questions about SHY. …”
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167
GenomeDelta: detecting recent transposable element invasions without repeat library
Published 2024-12-01“…GenomeDelta was validated with simulated and real data and used to discover three recent TE invasions in Drosophila melanogaster and a novel TE with geographic variation in Zymoseptoria tritici.…”
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168
DOSAGE COMPENSATION: REGULATION OF SEX CHROMOSOME GENE EXPRESSION
Published 2014-12-01“…Study of this process in the sex chromosomes of Drosophila melanogaster, Caenorhabditis elegans, and mammals has shown that, despite the common reason of dosage compensation origin, entirely different ways were elaborated to regulate X-linked gene expression level. …”
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169
The Redox System in C. elegans, a Phylogenetic Approach
Published 2012-01-01“…We use protein sequences from central redox systems in Homo sapiens, Drosophila melanogaster, and Saccharomyces cerevisiae to query Genbank for homologous proteins in C. elegans. …”
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170
uN2CpolyG-mediated p65 nuclear sequestration suppresses the NF-κB-NLRP3 pathway in neuronal intranuclear inclusion disease
Published 2025-02-01“…Treatment of CGG100 cells with lipopolysaccharide (LPS) significantly increased p-p65, NLRP3, and LC3II/LC3I levels while reducing insoluble uN2CpolyG levels and intranuclear inclusions. In the Drosophila knock-in model, LPS significantly reduced the number of intranuclear inclusions and improved phenotypic manifestations. …”
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171
МИТОТИЧЕСКИЙ ЦИКЛ И ЕГО РЕГУЛЯЦИЯ
Published 2015-01-01“…В настоящей статье будут кратко рассмотрены процессы клеточного цикла, включающие митоз, т. е. митотического цикла.Объектами изучения митотического цикла являются самые разные организмы, прежде всего те, генетика которых хорошо изучена: дрожжи Saccharomyces cerevisiae, Schyzosaccharomyces pombe, плесневый гриб Aspergillus nidulans, плодовая мушка Drosophila melanogaster. Многие важные данные получены в экспериментах с оплодотворенными ооцитами морского ежа Arbacia punctulata и лягушки Xenopus laevis, а также на клетках млекопитающих in vitro. …”
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172
Sulfurous Gases As Biological Messengers and Toxins: Comparative Genetics of Their Metabolism in Model Organisms
Published 2011-01-01“…To address this deficit, we use protein sequences from Homo sapiens to query Genbank for homologous proteins in Caenorhabditis elegans, Drosophila melanogaster, and Saccharomyces cerevisiae. …”
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173
DYRK1A (Dual-Specificity Tyrosine-Phosphorylated and -Regulated Kinase 1A): A Gene with Dosage Effect During Development and Neurogenesis
Published 2006-01-01“…It is expressed in neural progenitor cells and has been proposed to participate in the signaling mechanisms that regulate dendrite differentiation. In Drosophila, disruption of the homolog minibrain gene results in flies with reduced neuroblast proliferation, decreased numbers of central brain neurons, and learning/memory deficits. …”
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174
A Technique for Observing the Behaviour of Small Animals Under Field Conditions
Published 1976-01-01“…Recently, however, one of us (M.H.R.) studied the behaviour of Drosophila-sized flies that associate with orb-web spiders and spend long periods standing on the spider’s body. …”
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175
Incomplete divisions between sister germline cells require Usp8 function
Published 2024-09-01“…We then focus on recent discoveries that reveal the molecular mechanisms blocking abscission in Drosophila germline cells. The enzyme Usp8 was identified as vital for ensuring incomplete cytokinesis through the regulation of ESCRT-III ubiquitination and localization. …”
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176
The Zn- or Cu-Thionein Character of a Metallothionein Determines Its Metal Load When Synthesized in Physiological (Metal-Unsupplemented) Conditions
Published 2010-01-01“…The four MTs are two Drosophila (MtnA and MtnB), one yeast (Crs5), and one mouse (mMT1) metallothionein isoforms. …”
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177
Ensuring the Stability of the Genome: DNA Damage Checkpoints
Published 2001-01-01“…Checkpoint signalling in model systems including mice, Xenopus laevis, Drosophila melanogaster, and the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe have been useful in elucidating these pathways in mammalian cells. …”
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178
The role of feedback in the formation of morphogen territories
Published 2008-02-01“…In this paper, we consider a mathematical model for the forma-tion of spatial morphogen territories of two key morphogens: Wingless (Wg)and Decapentaplegic (DPP), involved in leg development of Drosophila. Wedefine a gene regulatory network (GRN) that utilizes autoactivation and cross-inhibition (modeled by Hill equations) to establish and maintain stable bound-aries of gene expression. …”
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179
Assessment of food toxicology
Published 2016-09-01“…A decrease of rodent animal testing with its limitations of high costs, low throughput readouts, inconsistent responses, ethical issues and concerns of extrapolability to humans have led to an increased use of these but also alternative lower hierarchy surrogate animal models (e.g. Drosophila melanogaster; Caenorhabditis elegans or Danio rerio) and efforts to integrate organotypic systems and stem cell-based assays. …”
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180
Dynamics and regulatory roles of RNA m6A methylation in unbalanced genomes
Published 2025-01-01“…RNA m6A modification in Drosophila has proven to be involved in sex determination regulated by Sxl and may affect X chromosome expression through the MSL complex. …”
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