Dietary fat quantity and composition influence hepatic lipid metabolism and metabolic disease risk in humans by Nikola Srnic, Felix Westcott, Eleanor Caney, Leanne Hodson

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Multi-omics analysis reveals distinct gene regulatory mechanisms between primary and organoid-derived human hepatocytes by Haoyu Wu, Annie S. P. Yang, Suzan Stelloo, Floris J. M. Roos, René H. M. te Morsche, Anne H. Verkerk, Maria V. Luna-Velez, Laura Wingens, Johannes H. W. de Wilt, Robert W. Sauerwein, Klaas W. Mulder, Simon J. van Heeringen, Monique M. A. Verstegen, Luc J. W. van der Laan, Hendrik Marks, Richárd Bártfai

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Abca4, mutated in Stargardt disease, is required for structural integrity of cone outer segments by John J. Willoughby, Abbie M. Jensen

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First person – Latifa Bakiri

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Development of a genetically tailored implantation hepatocellular carcinoma model in Oncopigs by somatic cell CRISPR editing by Lobna Elkhadragy, Maximillian J. Carlino, Luke R. Jordan, Thomas Pennix, Nahed Ismail, Grace Guzman, Jonathan P. Samuelson, Lawrence B. Schook, Kyle M. Schachtschneider, Ron C. Gaba

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Dose-dependent effects of Nrf2 on the epidermis in chronic skin inflammation by Michael Koch, Luca Ferrarese, Maya Ben-Yehuda Greenwald, Sabine Werner

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Prostatic Escherichia coli infection drives CCR2-dependent recruitment of fibrocytes and collagen production by Brandon R. Scharpf, Hannah Ruetten, Jaskiran Sandhu, Kyle A. Wegner, Sneha Chandrashekar, Olivia Fox, Anne E. Turco, Clara Cole, Lisa M. Arendt, Douglas W. Strand, Chad M. Vezina

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Gestational trophoblastic disease: understanding the molecular mechanisms of placental tumours by Alina Nicheperovich, Benjamin Schuster-Böckler, Máire Ní Leathlobhair

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Transcription factor networks de-liver insight into improving organoid-derived hepatocyte culture by Katie Pickup

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The Company of Biologists: celebrating 100 years by Sarah J. Bray, Stephen J. Royle, Holly A. Shiels, Daniel St Johnston

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First person – Michael Koch

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First person – Brandon Scharpf and Hannah Ruetten

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A new effLuc/Kate dual reporter allele for tumor imaging in mice by Latifa Bakiri, Mélanie Tichet, Carolina Marques, Martin K. Thomsen, Elizabeth A. Allen, Stefanie Stolzlechner, Ke Cheng, Kazuhiko Matsuoka, Massimo Squatrito, Douglas Hanahan, Erwin F. Wagner

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