The Aging GABAergic System and Its Nutritional Support by Demetra J. Mills

“…A decline in GABAergic function can also be specifically tied to declines in progesterone, allopregnanolone, and DHEA levels associated with aging. This decline in GABAergic function associated with hormone loss ultimately affects GABAergic inhibition or excitement and calcium regulation throughout the body. …”
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Effect of Metformin on Anthropometric Measurements and Hormonal and Biochemical Profile in Patients with Prediabetes by Mustafa Safiah, Dana Hyassat, Yousef Khader, Oraib Farahid, Anwar Batieha, Mohammed El-Khateeb, Kamel Ajlouni

“…Metformin use resulted in significant increase in luteinizing hormone (LH) and progesterone levels in males, while it was associated with significant increase in prolactin, follicular stimulating hormone (FSH), and dehydroepiandrostenedione-sulphate (DHEA-S) levels and significant decrease in total testosterone level in females. …”
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Pilot application of an inflammation and physiological dysregulation index based on noninvasive salivary biomarkers by Andrey I. Egorov, William Xue, Jason Kobylanski, Miyu Fuzawa, Shannon M. Griffin, Timothy J. Wade, Michael Nye

“…Samples were tested for the neuroendocrine biomarkers alpha-amylase, cortisol, and dehydroepiandrosterone (DHEA) as well as immune system/inflammation biomarkers C-reactive protein (CRP), interleukin (IL)-1β, IL-6 and total immunoglobulin A (IgA). …”
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Ｅｘｅｎａｔｉｄｅ对多囊卵巢综合征大鼠胰腺组织ＳＩＲＴ１表达的影响

“…【目的】 观察Ｅｘｅｎａｔｉｄｅ对多囊卵巢综合征（ＰＣＯＳ）大鼠胰腺沉默信息调节因子１ （ＳＩＲＴ１）表达的影响，探讨其对ＰＣＯＳ大鼠的干预治疗效果及可能机制。【方法】 采用脱氢表雄酮（ＤＨＥＡ）诱导建立（ｎ ＝ ５０）ＰＣＯＳ雌性大鼠模型，随机分成Ｅｘｅｎａｔｉｄｅ组（ＥＸ组，１０只），给予ＥＸ颈部皮下注射；二甲双胍组（ＭＦ组，１０只），给予ＭＦ无菌蒸馏水溶解灌胃；ＰＣＯＳ组（９只）及正常对照组（ＮＣ组，１０只）。…”
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Increased Frequency of CD4+ CD25+ FoxP3+ T Regulatory Cells in Pulmonary Tuberculosis Patients Undergoing Specific Treatment and Its Relationship with Their Immune-Endocrine Profil... by Ariana Díaz, Natalia Santucci, Bettina Bongiovanni, Luciano D’Attilio, Claudia Massoni, Susana Lioi, Stella Radcliffe, Griselda Dídoli, Oscar Bottasso, María Luisa Bay

“…While IL-6, IFN-γ, TGF-β (ELISA), and Cortisol (electrochemiluminescence, EQ) were augmented, DHEA-S (EQ) levels were diminished at T0 with respect to HCo, with cytokines and Cortisol returning to normal values at T9. …”
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艾塞那肽对多囊卵巢综合征大鼠胰岛素抵抗及生殖激素的影响

“…摘 要: 【目的】 探讨艾塞那肽(Exenatide)在多囊卵巢综合征(PCOS)大鼠胰岛素抵抗及生殖内分泌方面的作用?【方法】 采用脱氢表雄酮(DHEA)诱导建立PCOS雌性大鼠模型?建模成功后将大鼠随机分成4组:Exenatide组(EX组,10只),二甲双胍组(MF组,10只),多囊卵巢综合征组(PCOS组,9只)及正常对照组(NC组,10只)?…”
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Effects of Aerobic Exercise on Rats with Hyperandrogenic Polycystic Ovarian Syndrome by Na Li, Chenghao Yang, Huiyu Xie, Yinghong Liu, Yuanpeng Liao

“…The PC and PE groups were injected with a dehydroepiandrosterone (DHEA) solution to induce the hyperandrogenic PCOS rat model. …”
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A more accurate relationship between serum androgen and metabolism among healthy, nonobese, reproductive-age women based on liquid chromatography-tandem mass spectrometry by Sha Ye, Yepei Huang, Yi Lu, Xiaoyan Li, Meiling Ye, Hongyu Lu, Junhua Shi, Jian Huang, Hong Cai

“…Liquid chromatography-tandem mass spectrometry was used to measure androgen indicators, including testosterone, sex hormone-binding globulin (SHBG), free testosterone (FT), dihydrotestosterone (DHT), androstenedione (A4), dehydroepiandrosterone (DHEA), and dehydroepiandrosterone sulfate (DHEAS). …”
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外周血硫酸脱氢表雄酮水平对ＩＶＦ－ＥＴ中卵巢低反应与妊娠结局的预测价值

“…摘 要： 【目的】 评估月经早期外周血硫酸脱氢表雄酮（ＤＨＥＡＳ）水平对ＩＶＦ－ＥＴ助孕中卵巢低反应（ＰＯＲ）和妊娠结局的预测价值。【方法】 单中心回顾性队列研究。…”
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Effect of Basal Testosterone and Dehydroepiandrosterone Sulphate Levels on in Vitro Fertilization Outcome in Normoresponders by İnci Kahyaoğlu, Nafiye Yılmaz, Serkan Kahyaoğlu, Ayten Türkkanı, Mahmut Nedim Çiçek, Leyla Mollamahmutoğlu

“… OBJECTIVE: The purpose of the present study is to evaluate the predictive value of basal total testosterone (total-T) and dehydroepiandrosterone sulphate (DHEAS) levels in normoresponder patients undergoing IVF-ET. …”
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Functional Adrenocortical Adenoma in a Child with Beckwith–Wiedemann Syndrome by Leen Jamel Doya, Naya Talal Hassan, Hanin Ahmed Mansour, Mohammad Ahmad Almahmod Alkhalil, Abdul Alrahman Almahmod Alkhalil, Nada Mansour, Alaa Abdallah

“…This case report presents an 18-month-old girl with features suggestive of Beckwith–Wiedemann syndrome who developed pubic hair, high levels of testosterone, and DHEAS with normal cortisol and progesterone levels. …”
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Transient clitoromegaly in an extremely preterm twin infant with popliteal pterygium by Lavinia La Grasta Sabolić, Ana Kovačević, Lucija Ana Trtanj, Bernardica Valent Morić, Jasna Tumbri

“…During the following weeks, gradual normalisation of gonadotropin, testosterone, and DHEAS levels was accompanied by regression of clitoromegaly. …”
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Study on the potential diagnostic value of metabolomics changes in different biological fluids for aspiration pneumonia by Lianghui Chen, Yazhen Chen, Fansen Lin, Jianbao Wang, Hongzhi Gao, Yuqi Liu

“…DHEAS was found to be negatively correlated with the Acute Physiology and Chronic Health Evaluation II (APACHE II) (r = − 0.619, p = 0.005) in BALF sample. …”
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Plurihormonal Cosecretion by a Case of Adrenocortical Oncocytic Neoplasm by J. J. Corrales, C. Robles-Lázaro, A. I. Sánchez-Marcos, M. C. González-Sánchez, P. Antúnez-Plaza, J. M. Miralles

“…We describe an unusual case of a functional oncocytoma secreting an excess of glucocorticoids (cortisol) and androgens (androstenedione and DHEAS), a pattern of plurihormonal cosecretion previously not reported in men, presenting with endocrine manifestations of Cushing’s syndrome. …”
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Mastalgia Assesment and Hormonal Correlations in Patients with Polycystic Ovary Syndrome by Emel Kıyak Çağlayan, Levent Seçkin, Ayşe Yeşim Göçmen, Aylin Okur, Ergin Arslan, Halil İbrahim Serin, Kasım Çağlayan, Yaprak Engin Üstün

“…Age of the patients were noted, complaints of mastalgia were questioned and hormonal parameters (Follicle-Stimulating Hormone (FSH), Luteinizing Hormone (LH), Estradiol (E2), Testosterone, Dehydroepiandrosterone Sulphate (DHEAS), Thyroid-Stimulating Hormone (TSH), Body Mass Index (BMI)) were recorded. …”
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Diagnostic Utility of Various Hormones across Different Polycystic Ovary Syndrome Phenotypes: A Cross-sectional Study by Padala Ravi Kumar, Radha Krishna Telagareddy, Deepak Kumar Dash, Debasish Patro

“…Luteinising hormone (LH), follicle-stimulating hormone (FSH), LH/FSH ratio, androstenedione and DHEAS had low-to-moderate sensitivity across all phenotypes. …”
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Tramadol Induced Adrenal Insufficiency: Histological, Immunohistochemical, Ultrastructural, and Biochemical Genetic Experimental Study by Shereen Abdelhakim Abdelaleem, Osama A. Hassan, Rasha F. Ahmed, Nagwa M. Zenhom, Rehab A. Rifaai, Nashwa F. El-Tahawy

“…Tramadol decreased the levels of serum cortisol and DHEAS hormones. In addition, it increased the level of adrenal MDA and decreased the genetic expression of glutathione peroxidase and thioredoxin reductase in adrenal gland tissues. …”
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Vitamin D Supplementation Ameliorates Metabolic Dysfunction in Patients with PCOS: A SystematicReview of RCTs and Insight into the Underlying Mechanism by Shan Guo, Reshef Tal, Haoyu Jiang, Tao Yuan, Ying Liu

“…No significant impact was seen on serum triglyceride, total-C, LDL-C, HDL-C, total testosterone, DHEAS, SHBG, or hs-CRP. Subgroup analysis demonstrated that oral vitamin D intake had significantly decreased serum triglyceride and total-C level in women with PCOS who have vitamin D deficiency (serum vitamin D < 20 ng/ml). …”
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Bilateral Leydig Cell Hyperplasia: A Rare Cause of Postmenopausal Hirsutism by S. Pathmanathan, S. D. N. De Silva, M. Sumanatilleke, D. Lokuhetty, U. V. V. Ranathunga

“…Her biochemical evaluation showed elevated testosterone levels with normal DHEAS, ODST, 17-OHP, and prolactin. Low-dose dexamethasone suppression test did not suppress testosterone more than 40%. …”
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早初潮及GnRHa治疗女孩初潮后代谢和性腺轴的改变 by 陈秋莉, 李燕虹, 马华梅, 杜敏联, 陈红珊, 古玉芬

“…GnRHa治疗者初潮后BMISDS 和胰岛素、HOMA-IR及发生胰岛素的比例（20.7%）均较正常初潮组显著升高（P < 0.05）；同时，DHEAS、雄烯二酮和睾酮均 较早初潮组高，子宫体积较正常和早初潮组显著增大。【结论】早初潮及GnRHa治疗有可能对BMI和糖代谢产生负面影响， GnRHa治疗者还伴雄激素分泌功能相对稍亢进。…”
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