EPIGENETICS TODAY AND TOMORROW by B. F. Vanyushin

“…Epigenetic parameters are very significant for understanding of somaclonal variation mechanisms; characterization of clones and cell cultures, including stem cells at various differentiation stages; and determination of their differentiation directions. …”
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Prevalence of attention deficit hyperactive disorder (ADHD) symptoms in selected government primary schools in Wakiso District, Uganda by Josephine Ssirimuzaawo, Miph Musoke, Pio Frank Kiyingi

“…However, this district is very densely populated with people from different cultural and economic background, making it representative of the entire country Uganda. …”
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Interleukin-12 Inhibits Tumor Growth and Metastasis Promoted by Tumor-Associated Mesenchymal Stem Cells in Triple-Negative Breast Cancer by Babak Jahangiri, Zahra-Soheila Soheili, Elahe Asadollahi, Mehdi Shamsara, Vahid Shariati, Alireza Zomorodipour

“…Objective: The aim of this study was to understand the interactions between tumor-associated mesenchymal stemcells (TA-MSCs) and triple-negative breast cancer (TNBC) cells, which appear to be necessary for developing effectivetherapies.Materials and Methods: In this experimental study, MDA-MB-231 and 4T1 TNBC cells were co-cultured with bonemarrow-derived MSCs, and TA-MSCs conditioned media (CM) were collected. …”
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S’unir au Prophète. L’expérience matérielle, esthétique et dévotionnelle du Dalā’il al-Khayrāt au Maroc. Approches codicologique et anthropologique by Hiba Abid, Anouk Cohen

“…To this end, the article draws on codicological and anthropological approaches to the book to examine how the materiality of the object informs the cultural practices that are attached to it, and the material and aesthetic experience that it supports, in order to unite with the Prophet, and also reconfigures these.…”
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Healthy aging in frail older adults: Active aging project of a national survey by Jisu Seo, Kyungok Joo, Yuelin Li, Nayoung Kim, Eunna Oh, Lkhagvajav Gansukh, Rhayun Song

“…Further, we need to explore diverse social and cultural activities associated with healthy aging in this population to expand the definition of active aging.…”
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Effects of prolonged NaHCO3 exposure on the serum immune function, antioxidant capacity, intestinal tight junctions, microbiota, mitochondria, and autophagy in crucian carp (Carass... by Jia Liu, Faye Zhang, Zihao Yan, Zhengyao Guo, Yuqian Lu, Baolan Yao, Yuehong Li, Wenfa Lv

“…All of the experimental fish were cultured for 8 weeks. The results showed that compared to the control group, NaHCO3 stress significantly decreased the levels of the serum immunity indices (AKP, ACP, C3, C4, IgM, LZM) and the antioxidant capacity indices (CAT, GSH-PX, SOD, T-AOC), while markedly increasing the content of MDA. …”
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Hypothermia regulates mitophagy and apoptosis via PINK1/Parkin-VDAC 3 signaling pathway during oxygen-glucose deprivation/recovery injury by Luying Zhang, Song Yang, Hao Cui, Chenchen Hang, Xingsheng Wang, Le An, Zhenyu Shan, Zhen Liang, Rui Shao, Ziren Tang

“…In this study, BV2 mouse microglial cells were cultured under oxygen-glucose deprivation for 6 h following reperfusion with or without hypothermia for 2–4 h. …”
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Facilitators and barriers to reach and enrollment into a medically tailored meals program within a section 1115 Medicaid pilot: clinic staff perspectives by Sara C. Folta, Jessica Burch, Matthew Alcusky, Arlene S. Ash, Kurt Hager, Jean Terranova, Fang Fang Zhang, Oyedolapo Anyanwu, Zhongyu Li, Dariush Mozaffarian

“…Patient-related barriers included lacking a working phone or stable housing and concern about meals meeting taste and cultural food preferences. Staff-related barriers included limited time and especially knowledge about the MTM program.DiscussionThis study highlights the perspectives of front-line staff during the implementation of an MTM program in a state-wide 1,115 Demonstration. …”
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The development of a food-group, tree classification method and its use in exploring dietary associations with metabolic dysfunction-associated Steatotic liver disease (MASLD) and... by Amina A. Alawadi, Amrita Vijay, Jane I. Grove, Moira A. Taylor, Guruprasad P. Aithal

“…Conclusion: The study introduces a new food-group, tree classification method to characterise UK diet data and identify risk factors for MASLD, potentially informing the development of culturally applicable dietary guidelines designed to improve public health.…”
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“Space to see the future”? A political economy analysis of child and adolescent mental health and well-being in Ethiopia including routes for change by Kibur Engdawork, Kibur Engdawork, Kibur Engdawork, Lucia D’Ambruoso, Lucia D’Ambruoso, Lucia D’Ambruoso, Lucia D’Ambruoso, Lucia D’Ambruoso, Lucia D’Ambruoso, Tsion Hailu, Tsion Hailu, Tsion Hailu, Mahlet Yared, Mahlet Yared, Girma M. Geletu, Girma M. Geletu, Semere G. Baraki, Semere G. Baraki, Elias Sebsibe, Pamela Abbott

“…There is a pressing need to resource and support implementation and collaboration capabilities of the school community and healthcare sector to promote mental wellbeing and provide culturally engaged services.…”
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Estudio psicométrico del cuestionario de intenciones emprendedoras en jóvenes mexicanos - Psychometric study of the entrepreneurial intentions questionnaire in Mexican youth by Ignacio Norambuena, Felipe Quintano, Leonor Riquelme, José Sepúlveda, Cristina Tavera, Selene Pérez, Crisóforo Álvarez, Roque López

“…Its relevance as an instrument for future research in diverse educational and cultural contexts is underscored.…”
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Fermented sugarcane juice-derived probiotic Levilactobacillus brevis RAMULAB54 enhances lipid metabolism and glucose homeostasis through PPAR-γ activation by V. B. Chandana Kumari, Ramith Ramu, Sujay S. Huligere, Shashank M. Patil, Shivasharanappa Nayakvadi, Sharath Bijoor, Uma Venkateswaran Manjappara, Mohammad Z. Ahmed, Ling Shing Wong

“…This study is a novel approach that explores the antihyperglycemic and antihyperlipidemic effects of Levilactobacillus brevis RAMULAB54 (LB13243), isolated from fermented sugarcane juice. LB13243 was cultured for SEM imaging, and its supernatant (LBR54) was analyzed. …”
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Long non-coding RNA Malat1 modulates CXCR4 expression to regulate the interaction between induced neural stem cells and microglia following closed head injury by Qin Dong, Pengyu Chen, Wenqiao Qiu, Zhijun Yang, Yanteng Li, Yuhui Zhou, Lili Guo, Dan Zou, Ruxiang Xu, Mou Gao

“…Methods We performed bioinformatic analysis to detect the differentially expressed genes in iNSCs after co-cultured with LPS-activated microglia. Subsequently, we predicted the target genes and performed gain- and loss-of-functional studies, dualluciferase reporter, RNA immunoprecipitation, biotin-coupled miRNA pulldown, fluorescence in situ hybridization and cell transplantation assays to further elucidate the mechanism underlying the immunoregulatory effects of iNSCs. …”
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TCR-engaging scaffolds selectively expand antigen-specific T-cells with a favorable phenotype for adoptive cell therapy by Marco Donia, Özcan Met, Julie Westerlin Kjeldsen, Sine Reker Hadrup, Inge Marie Svane, Arianna Draghi, Anders Handrup Kverneland, Christina Heeke, Siri Amanda Tvingsholm, Marcus Svensson Frej, Vibeke Mindahl Rafa, Ulla Kring Hansen, Maria Ormhøj, Alexander Tyron, Agnete W P Jensen, Mohammad Kadivar, Amalie Kai Bentzen, Kamilla K Munk, Gitte N Aasbjerg, Jeppe S H Ternander, Tripti Tamhane, Christian Schmess, Samuel A. Funt, Søren Nyboe Jakobsen

“…Here, in this study, we present a novel technology for ex vivo expansion of antigen-specific T-cells; artificial antigen-presenting scaffolds (Ag-scaffolds) consisting of a dextran-polysaccharide backbone, decorated with combinations of peptide-Major Histocompatibility Complex (pMHC), cytokines and co-stimulatory molecules, enabling coordinated stimulation of antigen-specific T-cells.Methods The capacity of Ag-scaffolds to expand antigen-specific T-cells was explored in ex vivo cultures with peripheral blood mononuclear cells from healthy donors and patients with metastatic melanoma. …”
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Effects of Different Light Spectra on Oxidative Stress and Nutritional Quality of the Fish <i>Plectropomus leopardus</i> by Wensheng Li, Zheng Zhang, Baoliang Liu, Yingying Fang, Shuquan Cao, Wenyang Li, Yan Sun, Chengbin He, Chuanxin Zhang, Fan Fei

“…The fish (100 g ± 0.45 g [wet weight]) were cultures in five different light spectra (full-spectrum (400–800 nm), blue (450 nm), green (530 nm), red (630 nm), and dark) for 60 days. …”
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Influence of the Sodium Titanate Crystal Size of Biomimetic Dental Implants on Osteoblastic Behavior: An In Vitro Study by Saray Fernández-Hernández, Javier Gil, Daniel Robles-Cantero, Esteban Pérez-Pevida, Mariano Herrero-Climent, Aritza Brizuela-Velasco

“…The different surfaces were cultured with human osteoblastic cells; cell adhesion was determined at 3 and 14 days, and the degree of mineralization was determined at 14 days via alkaline phosphatase levels. …”
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Using the Oxford Foot Model to determine the association between objective measures of foot function and results of the AOFAS Ankle-Hindfoot Scale and the Foot Function Index: a pr... by Frank Krummenauer, Tanja Kostuj, Felix Stief, Kirsten Anna Hartmann, Katharina Schaper, Mohammad Arabmotlagh, Mike H Baums, Andrea Meurer, Sebastian Lieske

“…Objective After cross-cultural adaption for the German translation of the Ankle-Hindfoot Scale of the American Orthopaedic Foot and Ankle Society (AOFAS-AHS) and agreement analysis with the Foot Function Index (FFI-D), the following gait analysis study using the Oxford Foot Model (OFM) was carried out to show which of the two scores better correlates with objective gait dysfunction.Design and participants Results of the AOFAS-AHS and FFI-D, as well as data from three-dimensional gait analysis were collected from 20 patients with mild to severe ankle and hindfoot pathologies.Kinematic and kinetic gait data were correlated with the results of the total AOFAS scale and FFI-D as well as the results of those items representing hindfoot function in the AOFAS-AHS assessment. …”
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PU.1 alleviates the inhibitory effects of cigarette smoke on endothelial progenitor cell function and lung-homing through Wnt/β-catenin and CXCL12/CXCR4 pathways by Xue He⁺, Yanan Cui⁺, Tiao Li, Lijuan Luo, Zihang Zeng, Yiming Ma, Yan Chen

“…The angiogenic ability of BM-derived EPCs cultured in vitro was examined by tube formation assay. …”
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Enhancing the understanding of safety and the quality of patient care among medical and health sciences students in interprofessional climate: an interventional study by Salman Yousuf Guraya, Nabil Sulaiman, Ahmed Hasswan, Vida Abdolhamid Salmanpour, Feras Jassim Jirjees, Mohamed Hassan Taha, Jennat Alamara, Sausan A.L. Kawas, Manal Awad, Jacqueline Maria Dias, Leena R. David, Mohamed Aly Haider, Shaista Salman Guraya, Nihar Ranjan Dash, Amal Al-Qallaf, Sarra Shorbagi, Ibrahim Eltayeb Mahmoud

“…To ensure its validity across different settings, cultural adaptation was ensured with reiterative revision among the panel of experts. …”
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Pathogenic variants of TUBB8 cause oocyte spindle defects by disrupting with EB1/CAKP5 interactions and potential treatment targeting microtubule acetylation through HDAC6 inhibiti... by Hui Luo, Jianhua Chen, Cao Li, Tian Wu, Siyue Yin, Guangping Yang, Yipin Wang, Zhihan Guo, Saifei Hu, Yanni He, Yingnan Wang, Yao Chen, Youqiang Su, Congxiu Miao, Yun Qian, Ruizhi Feng

“…More importantly, selective inhibition of HDAC6 by culturing TUBB8‐D417N oocytes with Tubacin or Tubastatin A showed morphologically normal spindle and drastically recovered polar‐body extrusion rate. …”
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