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    Flare-IBD: development and validation of a questionnaire based on patients’ messages on an internet forum for early detection of flare in inflammatory bowel disease: study protocol... by Francis Guillemin, Jonathan Epstein, Anne Buisson, Laetitia Ricci, Corinne Devos, Yannick Toussaint

    Published 2020-07-01
    “…This study aimed to use an innovative methodology to collect messages posted by patients in an internet forum for developing and validating a PRO measuring flare in IBD.Methods and analysis The design involves (1) computer engineering sciences for scraping extraction of messages posted in an internet forum and for identification of messages related to flare; (2) qualitative methods for thematic content analyse of the messages posted, for candidate items generation, for items selection (Delphi process) and for items adjustment (‘think-aloud’ interviews) and (3) quantitative methods for psychometric validation of the PRO.Ethics and dissemination Ethical approval was obtained from the Comité de Protection des Personnes (CPP) CPP Nord-Ouest I (19.07.15.44139) in November 2019. …”
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