Gum Arabic Reduces C-Reactive Protein in Chronic Kidney Disease Patients without Affecting Urea or Indoxyl Sulfate Levels by Sarra Elamin, Mariam J. Alkhawaja, Amina Y. Bukhamsin, Mohamed A. S. Idris, Muntasir M. Abdelrahman, Nasrulla K. Abutaleb, Abdulrahman A. Housawi

“…This trial is registered with Saudi Clinical Trial Registry number 15011402.…”
Get full text

A Systematic Literature Review of Three Stenting Strategies for Bifurcation Lesions in Coronary Artery Disease by Larragem Parsley-Raines, Dominique M. Brandt, Dillon L. Carr, Sabrina Uhry, Eileen S. Alexander, Stephanie A. Donauer, Peter J. Mallow

“…**Methods:** Literature searches in Medline, Cochrane Library, Web of Science and Embase were conducted to identify prospective clinical trials from January 2007-July 2017. **Results:** 602 articles were identified. …”
Get full text

Chemical Chaperone of Endoplasmic Reticulum Stress Inhibits Epithelial-Mesenchymal Transition Induced by TGF-β1 in Airway Epithelium via the c-Src Pathway by Heung-Man Lee, Ju-Hyung Kang, Jae-Min Shin, Seoung-Ae Lee, Il-Ho Park

Get full text

Influence of psychological resilience on compassion fatigue in nurses in the operating room: a cross-sectional study in China by Cong Fu, Ying Wang, Xiaopan Shi, Yang Wang, Weihua Liu, Gaijing Wang

“…Appropriate interventions are recommended to address these factors and reduce nurses’ compassion fatigue. Clinical trial number Not applicable.…”
Get full text

Ultrasound-based abdominal muscles and diaphragm assessment in predicting extubation failure in patients requiring neurointensive care: a single-center observational study by Xiang Qiu, Chuanjuan Chen, Lan Lv, Bihui Yang, Zhiqiang Wang, Jun Ni

“…Trial registration: The study was registered on Chinese Clinical Trial Registry: ChiCTR2400088210, Registered 13 August 2024 - Retrospectively registered, https://www.chictr.org.cn/bin/project/edit?…”
Get full text

Association of Pregnancy Complications with Endometrial or Ovarian or Breast Cancer: A Case Control Study by Lin Cheng Han, Henry W. C. Leung, Heng-Jun Lin, John Hang Leung, Agnes L. F. Chan

Get full text

Tuberculosis vaccines and therapeutic drug: challenges and future directions by Yajing An, Ruizi Ni, Li Zhuang, Ling Yang, Zhaoyang Ye, Linsheng Li, Seppo Parkkila, Ashok Aspatwar, Wenping Gong

“…This review meticulously maps out the contemporary landscape of TB vaccine development, with a focus on antigen identification, clinical trial progress, and the obstacles and future trajectories in vaccine research. …”
Get full text

Biochemical Characterization of Early Osteoarthritis in the Ankle by Hagen Schmal, Gian M. Salzmann, Elia R. Langenmair, Ralf Henkelmann, Norbert P. Südkamp, Philipp Niemeyer

“…Methods. 49 patients with a mean age of 33±14 years undergoing an arthroscopy of the ankle with different stages of chronic OA were prospectively included in a clinical trial. Lavage fluids were analyzed by ELISA. …”
Get full text

Efficacy of vaccines based on chimeric or multiepitope antigens for protection against visceral leishmaniasis: A systematic review. by Karine Ferreira Lopes, Mariana Lourenço Freire, Silvane Maria Fonseca Murta, Edward Oliveira

“…<h4>Principal findings</h4>A total of 22 studies were selected, with only one being a randomized clinical trial. Most of the studies were conducted with mice, followed by dogs and hamsters. …”
Get full text

Comparison of the effects of lidocaine and articaine used for buccal infiltration and supplemental palatinal infiltration anesthesia in maxillary molars with irreversible pulpitis:... by Duygu Kolay, Damla Kırıcı

“…Conclusions According to the results of this study, it may be recommended to use palatal infiltration anesthesia in addition to buccal infiltration anesthesia, independent of the anesthetic solution, for an effective pulpal anesthesia in maxillary molars with irreversible pulpitis. Clinical trial registration Registration number is “NCT06342869” and date of registration is 2024-04-02.Retrospectively registered.…”
Get full text

Impact of Enhanced recovery after surgery (ERAS) protocols in idiopathic scoliosis of children: A systematic review with meta-analysis and trial sequential analysis by Soumya Sarkar, Bharat Yalla, Bhavuk Garg, Puneet Khanna

“…Methods: Studies comparing ERAS with conventional pathways for spinal surgery in children with idiopathic scoliosis were included after scrutiny of electronic databases (PubMed, Medline, and Embase), Google Scholar, preprint, and clinical trial databases after the protocol was enroled in PROSPERO (ID: CRD42023418323). …”
Get full text

Medium- to long-term functional outcomes of artcure diffusional patch therapy for lumbar disc herniation: which herniation is more likely to require surgery? by Zekeriya Ersin Çelen, Furkan Hanege, Soner Sarı, Bülent Özkurt

“…Patients with MSU grade two and three herniations should be monitored more closely, as they are more likely to experience a later surgical intervention. Clinical trial number Not applicable.…”
Get full text

The Pharmacodynamic Impact of Apremilast, an Oral Phosphodiesterase 4 Inhibitor, on Circulating Levels of Inflammatory Biomarkers in Patients with Psoriatic Arthritis: Substudy Res... by Peter H. Schafer, Peng Chen, Lorraine Fang, Andrew Wang, Rajesh Chopra

“…Apremilast, an oral phosphodiesterase 4 inhibitor, demonstrated effectiveness (versus placebo) for treatment of active psoriatic arthritis in the psoriatic arthritis long-term assessment of clinical efficacy (PALACE) phase III clinical trial program. Pharmacodynamic effects of apremilast on plasma biomarkers associated with inflammation were evaluated in a PALACE 1 substudy. …”
Get full text

Listeria Contamination in Milk-Processing Chain and Proficiency in Listeria monocytogenes Decontamination of Small-Scale Milk Retailers by Suppada Kananub, Papavarin Lertsakkongkul, Patsara Aryatawong, Wilailak Horhirunkhajohn, Nayika Pinniam, Praphaphan Krajanglikit, Kamonrat Sonthong, Suwicha Kasemsuwan

“…Milk samples were collected from milk-collecting centers and small-scale retailers. In clinical trial, the processing measures were proved for the proficiency in L. monocytogenes decontamination. …”
Get full text

Effect of Existential Group Therapy on the Quality of Sexual Life in Infertile Men\'s Spouses by samira ghorbani, Shahrbanoo Salehin, Ali Mohamad Nazari, Seyedeh Solmaz Talebi, Afsaneh Keramat

“…Materials and Methods: The present study followed a randomized controlled clinical trial from 2020-2021 on 96 women aged 20-45 with male-caused infertility. …”
Get full text

An Alternative Model of Care for the Treatment of Adolescent Athletes with Extension-Based Low Back Pain: A Pilot Study. by Mitchell Selhorst, Richard Rodenberg, Nick Padgett, Anastasia Fischer, Reno Ravindran, James MacDonald

“… # Study Design Non-randomized, controlled clinical trial. # Methods Sixteen adolescents (15 ± 1.8 years, 50% female) with extension-based LBP were assigned to the biomedical model or physical therapy first model. …”
Get full text

Effectiveness of a novel amine + zinc + fluoride toothpaste in reducing plaque and gingivitis: results of a six-month randomized controlled trial by Dutmanee Seriwatanachai, Terdphong Triratana, Petcharat Kraivaphan, Norbert Huber, Tilo Poth, Luis R. Mateo, Melissa Stellitano, Yun-Po Zhang

“…Clinical relevance These results suggest that daily use of amine + zinc + fluoride toothpaste can provide a significant improvement in managing plaque accumulation and bleeding associated with gingival inflammation especially for patients experiencing gingivitis. Clinical trial registration NCT06563518 (registration date: August 19, 2024).…”
Get full text

Long-Term GAD-alum Treatment Effect on Different T-Cell Subpopulations in Healthy Children Positive for Multiple Beta Cell Autoantibodies by Falastin Salami, Lampros Spiliopoulos, Marlena Maziarz, Markus Lundgren, Charlotte Brundin, Rasmus Bennet, Magnus Hillman, Carina Törn, Helena Elding Larsson

“…The Diabetes Prevention–Immune Tolerance 2 (DiAPREV-IT 2) clinical trial enrolled 26 children between 4 and 13 years of age, positive for glutamic acid decarboxylase autoantibody (GADA) and at least one other autoantibody (insulin, insulinoma antigen-2, or zinc transporter 8 autoantibody (IAA, IA-2A, or ZnT8A)) at baseline. …”
Get full text

Functional MRI-guided microsurgery of intracranial arteriovenous malformations: study protocol for a randomised controlled trial by Shuo Wang, Yuanli Zhao, Jun Wu, Bing Zhao, Yong Cao

“…Study findings will be disseminated in the printed media.Trial registration number ClinicalTrials.gov NCT01758211.…”
Get full text

Lidocaine Versus Ketamine Pretreatment on Propofol Injection Pain by Amir Murad Khudadad Boujan, Nashmeel fazeel Kareem, Amanj A. Marouf, Saman Abdullah Ahmed Fahmi, Salah Qadir Mahmood

“…This study is randomized controlled clinical trial lasting from June 2015 to November 2015 during which 107 consenting (ASA1 and ASA2) patients were prepared for elective operation with general anesthesia. …”
Get full text