Cognitive Stimulation for Apathy in Probable Early-Stage Alzheimer's by Linda L. Buettner, Suzanne Fitzsimmons, Serdar Atav, Kaycee Sink

“…We studied changes in apathy among 77 community-dwelling older persons with mild memory loss in a randomized clinical trial comparing two nonpharmacological interventions over four weeks. …”
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Update on Remdesivir in the Treatment of Novel Coronavirus Pneumonia by Huang Feng, K. Vijaya Lakshmi, Chin Tat Ng, Murthy Sasikumar, Masita Arip, Masriana Hassan, Voon Kin Chin, Mogana Rajagopal, Omotayo Fatokun, N. Parvathi, Malarvili Selvaraja

“…More importantly, the outcome of current clinical trials of Remdesivir alone and when combined with other drugs for COVID-19 management was analyzed, and the limitations and clinical significance of each clinical trial were evaluated. …”
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Effect of Posture Training with Weighted Kypho-Orthosis (WKO) on Improving Balance in Women with Osteoporosis by Seyed Ahmad Raeissadat, Leyla Sedighipour, Safura Pournajaf, Reza Vahab Kashani, Shahram Sadeghi

“…In this nonrandomized controlled clinical trial, 31 patients with osteoporosis were included. …”
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Therapeutic rigid bronchoscopy for endobronchial glomus tumors: a case series by Rong Lih Ho, Byeong-Ho Jeong, Joungho Han, Hojoong Kim

“…Conclusion Endoscopic resection and laser cauterization using rigid bronchoscopy may be a viable option for patients with endobronchial GT when surgery is not practical. Clinical trial number Not applicable.…”
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Comparison of Patient Outcomes following Implantation of Trifocal and Extended Depth of Focus Intraocular Lenses: A Systematic Review and Meta-Analysis by Yining Guo, Yinhao Wang, Ran Hao, Xiaodan Jiang, Ziyuan Liu, Xuemin Li

“…A comprehensive search of PubMed, Cochrane Library, EMBASE, and ClinicalTrial.gov was conducted in March 2020 to identify relevant studies. …”
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Causes and Clinical Impact of Loss to Follow-Up in Patients with Proliferative Diabetic Retinopathy by Hazem Abdelmotaal, Walid Ibrahim, Mohamed Sharaf, Khaled Abdelazeem

“…Possibly, patient-specific LTFU causes should be addressed before treatment in order to minimize the risk of LTFU. The clinical trial is registered with NCT04018326 (trial registration: ClinicalTrials.gov Identifier: NCT04018326, 10th of July 2019 “Retrospectively registered”).…”
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Randomized controlled trial on the efficacy of forest walking compared to urban walking in enhancing mucosal immunity by Hiroko Ochiai, Shigeru Inoue, Gaku Masuda, Shiho Amagasa, Tomohiko Sugishita, Toshiya Ochiai, Naoko Yanagisawa, Yoshio Nakata, Michiko Imai

“…In conclusion, mindful forest walking has the potential to enhance immunity and promote health. Clinical trial registration: University Hospital Medical Information Network. …”
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The Effect of Implementing Self-Compassion Program on Moral Injury of Nursing Students by Hanie Dahmardeh

“…Methods: In this clinical trial study, 150 nursing students of the 7th and 8th semesters in the intership course of Zahedan School of Nursing in 2023 were randomly selected in two groups of 75, intervention and control. 8 sessions of face-to-face educational program were designed and implemented for students and the degree of application of the programs by them was followed up under the supervision of the researcher. …”
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Effect Of Non-Oral Stimulation With Field Massage On The Time Of Onset And Achievement Of Independent Oral Feeding And Weight GainIn Premature Infants by Naghmeh Razaghi, najmeh zabihi torbati, hamidreza behnam vashani, mohammad Heidarzadeh

“…Materials and Methods: Randomized clinical trial, 60 premature babies of 28-32 weeks in the NICU department of Ommolbanin Hospital, Mashhad met the criteria for entering the study, were selected and placed in two groups of field massage and control by simple random allocation. …”
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Hemorheological Alterations in Patients with Heart Failure with Reduced Ejection Fraction Treated by Resveratrol by Roland Gal, Dora Praksch, Peter Kenyeres, Miklos Rabai, Kalman Toth, Robert Halmosi, Tamas Habon

“…In our double-blind, placebo-controlled human clinical trial, we enrolled 60 outpatients with heart failure. …”
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Physical health and ecological momentary assessments during COVID-19: Data from the ‘Corona Health’ app usersZenodo by Johannes Allgaier, Felizitas Eichner, Stefan Störk, Peter Heuschmann, Rüdiger Pryss

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Profile of Chlamydia vaccine research: A bibliometric analysis by Xuemei Wang, Qian Wang, Yidan Gao, Lijuan Jiang, Lingli Tang

“…However, to date, no vaccine has successfully completed the rigorous clinical trial process and gained regulatory approval for use in clinical practice. …”
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Improvement of Renal Function by Long-Term Sustained Eculizumab Treatment in a Patient with Paroxysmal Nocturnal Hemoglobinuria by Haruhiko Ninomiya, Naoshi Obara, Akiko Niiori-Onishi, Yasuhisa Yokoyama, Mamiko Sakata-Yanagimoto, Yuichi Hasegawa, Shigeru Chiba

“…We administered eculizumab to a patient with PNH, who was one of 29 patients enrolled in the AEGIS clinical trial, an open-label study of eculizumab in Japan. …”
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Transcatheter mitral valve replacement to treat rheumatic mitral stenosis: a case series by Ping Jin, Hong Guo, Yu Mao, Mengen Zhai, Yang Liu, Jian Yang

“…The early results of the procedure are acceptable and provide bright prospects and directions for the precision treatment of RMS. Clinical Trial RegistrationClinicalTrials.gov, identifier (NCT02917980).…”
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The effect of transcutaneous auricular vagus nerve stimulation on cardiovascular function in subarachnoid hemorrhage patients: A randomized trial by Gansheng Tan, Anna L Huguenard, Kara M Donovan, Phillip Demarest, Xiaoxuan Liu, Ziwei Li, Markus Adamek, Kory Lavine, Ananthv K Vellimana, Terrance T Kummer, Joshua W Osbun, Gregory J Zipfel, Peter Brunner, Eric C Leuthardt

“…Methods: In this randomized clinical trial, 24 SAH patients were assigned to either a taVNS treatment or a sham treatment group. …”
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Multi-omics uncovers immune-modulatory molecules in plasma contributing to resistance exercise-ameliorated locomotor disability after incomplete spinal cord injury by Ren Zhou, Jibao Chen, Yunhan Tang, Chuijin Wei, Ping Yu, Xinmei Ding, Li’ao Zhu, Jiajia Yao, Zengqiang Ouyang, Jing Qiao, Shumin Xiong, Liaoliao Dong, Tong Yin, Haiqing Li, Ye Feng, Lin Cheng

“…Methods We conducted a randomized controlled clinical trial investigating the effects of resistance exercise therapy for incomplete SCI. …”
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Azithromycin to prevent acute lower respiratory infections among Australian and New Zealand First Nations and Timorese children (PETAL trial): study protocol for a multicentre, int... by Anne B Chang, Keith Grimwood, Yuejen Zhao, Gabrielle B McCallum, Catherine A Byrnes, Heidi Smith-Vaughan, Peter S Morris, Christine Connors, Adrian Trenholme, Shirley Lawrence, Joshua Francis, Kobi L Schutz, Mark D Chatfield, Nevio Sarmento, Robyn L. Marsh, Emily R Bowden, Nicholas Fancourt, Adriano Vieira, Kim M Hare, Dennis Bonney, Felicity Marwick, Bronwyn Karvonen, Carolyn Maclennan, Milena Santos Lay, Endang Soares da Silva

“…The study outcomes will be disseminated to academic and medical communities via international peer-reviewed journals and conference presentations, and findings reported to health departments and consumer-based health organisations.Clinical trial registration Australia New Zealand Clinical Trial Registry ACTRN12619000456156.…”
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Modulation of myeloid and T cells in vivo by Bruton’s tyrosine kinase inhibitor ibrutinib in patients with metastatic pancreatic ductal adenocarcinoma by Li Zhang, Matthew Crocker, Lawrence Fong, Lisa M Coussens, Charles D Lopez, Shamilene Sivagnanam, Meenal Sinha, Brandon Chen, Jaqueline Marquez, Alexander Cheung, Whitney Tamaki, Jacob Stultz, Kendra Todd, Courtney Betts, Madeline J Griffith, Isabelle Solman, Eric Liu, Denise Pener, Anne Fahlman, Erin Taber, Kimberly Lerner, Brindha Rajagopalan, Clarisha Ware, Mark Bridge, Johnson Vo, Hannah Dragomanovich, Julie Sudduth-Klinger, Gina Vaccaro, Margaret Tempero

“…This led to a phase 1b clinical trial to determine the safety, tolerability, and immunologic effects of ibrutinib treatment in patients with advanced PDAC.Methods Previously untreated patients with PDAC were enrolled in a phase 1b clinical trial (ClinicalTrials.gov) to determine the safety, toxicity, and maximal tolerated dose of ibrutinib when administered with the standard regimen of gemcitabine and nab-paclitaxel. …”
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A scoping review of randomized trials assessing the impact of n-of-1 trials on clinical outcomes. by Joyce P Samuel, Susan H Wootton, Travis Holder, Donald Molony

“…Our objective was to provide an overview of the clinical trial evidence on the effect of n-of-1 trials on clinical outcomes.…”
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Cost-effectiveness of Ruxolitinib vs Best Available Therapy in the Treatment of Myelofibrosis in Spain by María Teresa Gómez-Casares, Juan Carlos Hernández-Boluda, Antonio Jiménez-Velasco, Joaquin Martínez-López, María Giovanna Ferrario, Irmina Gozalbo, Joana Gostkorzewicz, Rudi Subirá

“…The population was assumed to be similar to that of the COMFORT-II clinical trial (CT), which was also the source of treatment efficacy data. …”
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