Inhibitory Effect of (2S)-Pinocembrin From Goniothalamus macrophyllus on the Prostaglandin E2 Production in Macrophage Cell Lines by Hilwan Yuda Teruna, Kamal Rullah, Rudi Hendra, Rahayu Utami, Deri Islami, Siti Munirah Mohd Faudzi, Mohd Fadhlizil Fasihi Mohd Aluwi, Kok Wai Lam

“…Pinocembrin (PCB), a flavonoid known for its anti-inflammatory properties, has been approved for various clinical trial applications. To evaluate deeper into the anti-inflammatory potential of the specific enantiomer of natural PCB, we conducted the first investigation into the efficacy of the pure enantiomer (2S)-PCB in modulating inflammatory mediators induced by lipopolysaccharide (LPS) in both murine RAW 264.7 and human U937 macrophage cell lines. …”
Get full text

Mitigating soil compaction and enhancing corn (Zea mays L.) growth through biological and non-biological amendments by Shahrzad Hejazi Mahabadi, Mahdi Shorafa, Babak Motesharezadeh, Hassan Etesami

“…Future research should focus on understanding the underlying mechanisms of these interactions and their long-term implications for soil health and agricultural sustainability. Clinical trial number Not applicable.…”
Get full text

Barriers faced by undergraduate dental students when conducting research: a qualitative study by Mohammed Mahmoud Sarhan, Lama Nasser Aljohani, Raghad Ibrahim Alsaleh, Roze Abdulaziz Mubaraki, Malak Abdulaziz Almozaen, Rimas Sabih Alharbi

“…Additional qualitative research in this area would help to reveal further details of the barriers to research, while additional quantitative studies are required to assess the frequency and trends of the newly revealed barriers. Clinical trial number Not applicable.…”
Get full text

Sex differences in the association between repetitive negative thinking and neurofilament light by Yolanda Lau, Amit Bansal, Cassandre Palix, Harriet Demnitz-King, Miranka Wirth, Olga Klimecki, Gael Chetelat, Géraldine Poisnel, Natalie L. Marchant, The Medit-Ageing Research Group

“…Baseline data from 134 cognitively healthy older adults in the Age-Well clinical trial were utilised. Worry and brooding were assessed using questionnaires. …”
Get full text

Nondigital skin ulcers in systemic sclerosis: A neglected entity by Benzeeta Pinto, Ramya Janardana, Sowmya Kaimal, B Sheba Charles, K N Sangeeta, Jasmine Mathew, Kodishala Chanakya, John Michael Raj, Vineeta Shobha

“…There is an unmet need to incorporate non-DU in clinical trial outcomes and address them in patient management guidelines.…”
Get full text

Quantum secure patient login credential system using blockchain for electronic health record sharing framework by M. Natarajan, A. Bharathi, C. Sai Varun, Shitharth Selvarajan

“…In healthcare, BCT can help with mobile health apps, monitoring equipment, sharing and keeping of clinical trial data, electronic medical records, and insurance information storage. …”
Get full text

Empowering nursing students: understanding and addressing bullying experiences in clinical training by Maryam Janatolmakan, Saeedeh Piri, Mohammad Amin Nouri, Alireza Khatony

“…Additionally, healthcare organizations must take the initiative to develop anti-bullying policies to mitigate this challenge. Clinical trial number Not applicable.…”
Get full text

Study on the Correlation between Pain and Cytokine Expression in the Peripheral Blood of Patients with Bone Metastasis of Malignant Cancer Treated Using External Radiation Therapy by Yaling Lou, Yu Chen, Yumei Yuan, Ronghua Wang, Hanmin Shan

“…In this nonrandomized controlled clinical trial study, we focused on the relationship between bone metastasis, pain, and cytokines before and after radiotherapy. …”
Get full text

Completion of a standardizable competency-based research training program improves understanding and preparedness for both new and experienced clinical research professionals by Lucy Palmer, Sandra E. Morones, Heidi T. Jacobe, Rhonda Oilepo

“…The Joint Task Force for Clinical Trial Competency created a competency framework for CRPs, which has demonstrated positive results from various institutions, but training programs have been limited in standardization, replicability, and dissemination. …”
Get full text

Cost-Effectiveness of Bariatric Surgery in Patients Living with Obesity and Type 2 Diabetes by Gábor Kovács, Elemér Mohos, János Tibor Kis, Ádám Tabák, Péter Gerendy, Judit Pettkó, Dávid Nagy, Dávid Győrbíró, Zoltán Kaló

“…The aim of the current analysis was to demonstrate the cost-effectiveness of bariatric surgeries in obese patients with type 2 diabetes in Hungary compared to conventional diabetes treatments based on economic modelling of published clinical trial results. Materials and Methods. Patients entered the simulation model at the age of 45 with body mass index BMI≥30 kg/m2 and type 2 diabetes. …”
Get full text

The Effects of Vestibular Rehabilitation on Poststroke Fatigue: A Randomized Controlled Trial Study by Amin Ghaffari, Bahador Asadi, Armin Zareian, Malahat Akbarfahimi, Gholam Reza Raissi, Fahimeh Fathali Lavasani

“…Patients with a history of stroke took part voluntarily in a single-blind clinical trial. The participants were allocated to control and experimental groups randomly. …”
Get full text

Mobile Phone Short Message Service (SMS) for Weight Management in Iranian Overweight and Obese Women: A Pilot Study by Somayeh Faghanipour, Eftekharalsadat Hajikazemi, Soghra Nikpour, Shabnam al-Sadat Shariatpanahi, Agha Fatemeh Hosseini

“…Text messaging seems to be an effective channel of communication for weight management in Iranian overweight and obese women. The clinical trial registration number is IRCT201204029360N1.…”
Get full text

Interaction of physostigmine with three injectable anaesthetics in a young chick model by H. M. S. Garmavy, F. K. Mohammad

“…In conclusion, the results suggest that physostigmine, being a cholinergic stimulant, could specifically antagonise propofol anaesthesia in the young chick model, with clinical trial awaiting further studies.…”

Effect of Omega-3 on Recurrent Aphthous Stomatitis and Improvement Quality of Life by Zahra Hadian, Ali Akbar Moghadamnia, Sohrab Kazemi, Atena Shirzad

“…In this double-blind clinical trial, 40 patients with minor recurrent aphthous stomatitis were randomly divided into case and control groups. …”
Get full text

Photobiomodulation Therapy Plus Usual Care Is Better than Usual Care Alone for Plantar Fasciitis: A Randomized Controlled Trial by Ann K Ketz, Juanita Anders, Judy Orina, Betty Garner, Misty Hull, Nicholas Koreerat, Jeff Sorensen, Candice Turner, James Johnson

“… # Study Design Prospective, randomized controlled clinical trial # Methods A convenience sample of adults with PF were randomly assigned to one of three groups: (1) usual care, (2) usual care plus nine doses of PBMT with 25W output power over three weeks, or (3) usual care plus nine doses of PBMT with 10W output power over three weeks. …”
Get full text

Digital humanistic program to manage premature frailty in young breast cancer survivors with gender perspective by Yun Hu, Joshua Wiley, Lulu Jiang, Xiyi Wang, Ran Yi, Jiehui Xu, Yanyan Liu, Aozhou Weng, Futai Zou, Eun-Ok Im

“…This randomized controlled trial, registered at the Chinese Clinical Trial Registry (ChiCTR2200058823), tests the “AI-TA” program’s efficacy on premature frailty and quality of life in YBCSs. …”
Get full text

Efficacy of Topical Corticosteroid Monotherapy in Inducing and Maintaining Clinical and Histologic Remission in Adolescent and Adult Patients with Eosinophilic Esophagitis: a Syste... by A. A. Makushina, O. A. Storonova, A. S. Trukhmanov, T. L. Lapina, V. T. Ivashkin

“…A systematic literature search using defined keywords was performed up to March 20, 2021 in the MEDLINE / PubMed, EMBASE (Excerpta Medica), and Cochrane Central Register of Controlled Trials, ClinicalTrial.gov databases.Results. 390 patients from 5 studies were included in this systematic review with meta-analysis. …”
Get full text

Are medical school preclinical tests biased for sex and race? A differential item functioning analysis by Esther Dasari Dale, Mohammed A. A. Abulela, Hao Jia, Claudio Violato

“…Item level DIF should also be routinely conducted as part of psychometric analyses for basic sciences courses and other assessments. Clinical trial number Not applicable.…”
Get full text

Does the Direction of Kinesiology Tape Application Influence Muscle Activation in Asymptomatic Individuals? by Michelle Dolphin, Gary Brooks, Blair Calancie, Adam Rufa

“… # Levels of Evidence Level 1 – Controlled Clinical Trial # Clinical Relevance Kinesiology tape is commonly used as an intervention for a wide range of musculoskeletal conditions and for promoting performance including sporting activities. …”
Get full text

Changes in Cortical Activation Patterns in Language Areas following an Aerobic Exercise Intervention in Older Adults by Joe Nocera, Bruce Crosson, Kevin Mammino, Keith M. McGregor

“…The current work is registered as clinical trial with NCT01787292 and NCT02787655.…”
Get full text