Effectiveness of app-based cognitive behavioral therapy for insomnia on preventing major depressive disorder in youth with insomnia and subclinical depression: A randomized clinical trial by Si-Jing Chen, Jian-Yu Que, Ngan Yin Chan, Le Shi, Shirley Xin Li, Joey Wing Yan Chan, Weizhen Huang, Chris Xie Chen, Chi Ching Tsang, Yuen Lam Ho, Charles M. Morin, Ji-Hui Zhang, Lin Lu, Yun Kwok Wing

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Efficacy of Simple Eye Ointment, Polyethylene Cover, and Eyelid Taping in Prevention of Ocular Surface Disorders in Critically Ill Patients: A Randomized Clinical Trial by Mehdi Ahmadinejad, Esmat Karbasi, Yunes Jahani, Maryam Ahmadipour, Maryam Soltaninejad, Zahra Karzari

“…This study was a double-blind clinical trial (IRCT: 201109225426N3, https://www.irct.ir/trial/5825), in which 152 patients were randomized into three groups and each group underwent a different eye care procedure. …”
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The effectiveness and risks of Treating people with Idiopathic Pulmonary fibrosis with the Addition of Lansoprazole (TIPAL): study protocol for a randomised placebo-controlled multicentre clinical trial by Toby M Maher, A John Simpson, Anthony Cahn, David Thickett, Luke Vale, Allan B Clark, Nazia Chaudhuri, Ian Forrest, Lisa G Spencer, Christopher Ward, Stephen Jones, Ganesh Raghu, Andrew M Wilson, Helen Parfrey, Megan Jones, Matthew Hammond, Jaclyn Ann Smith, Shajahan Wahed

“…Trial results will be published in a peer-reviewed journal upon completion.Trial registration number ISRCTN13526307; ClinicalTrials.gov NCT04965298.…”
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Increasing Dose of Autologous Bone Marrow Mononuclear Cells Transplantation Is Related to Stroke Outcome: Results from a Pooled Analysis of Two Clinical Trials by Francisco Moniche, Paulo Henrique Rosado-de-Castro, Irene Escudero, Elena Zapata, Francisco Javier de la Torre Laviana, Rosalia Mendez-Otero, Magdalena Carmona, Pilar Piñero, Alejandro Bustamante, Lucía Lebrato, Juan Antonio Cabezas, Alejandro Gonzalez, Grabriel R. de Freitas, Joan Montaner

“…BM-MNC transplantation improves recovery in experimental models of ischemic stroke. Clinical trials are ongoing to test efficacy in stroke patients. …”
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The effects of gluteal stretching vs. Lightback® on hip rotation range of motion and posterior chain flexibility in healthy subjects: a cross-over clinical trial by Charles Cotteret, Jaime Almazán-Polo, Fabien Guérineau, Ángel González de-la-Flor

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A clinical study of the immunogenicity and protective potency of a live recombinant GamLPV vaccine for intranasal use for the prevention of whooping cough in adult volunteers by Alevtina A. Lidzhieva, Alisa Yu. Medkova, Sergey V. Kulikov, Ludmila N. Sinyashina, Rezida A. Sioundioukova, Andrey P. Markov, Aleksey B. Verveda, Natalia E. Abaeva, Irina N. Chernyshova, Marina V. Gavrilova, Kristina K. Bushkova, Ilya N. Dyakov, Gennady I. Karataev

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Comparison of Clinical and Radiographic Success between MTA and Biodentine in Pulpotomy of Primary Mandibular Second Molars with Irreversible Pulpitis: A Randomized Double-Blind Clinical Trial by Alireza Eshghi, Maryam Hajiahmadi, Mohammad Hossein Nikbakht, Mona Esmaeili

“…This study was conducted as a randomized double-blind clinical trial. Participants were selected according to inclusion criteria and 52 samples were randomly selected using random numbers table in group A. …”
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Naturally Occurring Canine Invasive Urinary Bladder Cancer: A Complementary Animal Model to Improve the Success Rate in Human Clinical Trials of New Cancer Drugs by Christopher M. Fulkerson, Deepika Dhawan, Timothy L. Ratliff, Noah M. Hahn, Deborah W. Knapp

“…Genomic analyses are defining further intriguing similarities between InvUC in dogs and that in humans. Multiple canine clinical trials have been completed, and others are in progress with the aim of translating important findings into humans to increase the success rate of human trials, as well as helping pet dogs. …”
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Investigating the effectiveness of theory-based interventions for improving treatment adherence of patients with type 2 Diabetes Mellitus: A systematic review of Randomised Controlled Clinical Trials by Despoina Menti, Caroline Limbert, Georgios Lyrakos

Efficacy and Safety of Murivenna Anal Infiltration Compared to Diltiazem Topical Application in Chronic Anal Fissure: Protocol for a Prospective, Randomized, Open-Label Clinical Trial by Pratap Shankar KM, Indu Puthan Purayil, Palengara Binitha, Amit Kumar Rai, Sophia Jameela, Azeem Ahmad, Chandra Sekhara Rao Bhogavalli, Narayanam Srikanth, Rabinarayan Acharya

“…MethodsThis is an open-labeled, randomized, controlled parallel group clinical trial with a sample size of 66 participants to be randomized and allocated in a 1:1 ratio to 2 groups. …”
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Role of adductor canal block and genicular nerve block on postoperative pain and enhanced recovery in patients undergoing total knee arthroplasty: A randomized clinical trial by Bassel Mohammed Elfokery, Mustafa Seet, Tareef Ashour, Hatem Alharbi, Mujeeb Ashraf, Hatim Alshareef, Mohammad Nyaz, Rayan Bakhreba, Atif Sait

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The Threshold of the Severity of Diabetic Retinopathy below Which Intensive Glycemic Control Is Beneficial in Diabetic Patients: Estimation Using Data from Large Randomized Clinical Trials by Yuqi Liu, Juan Li, Jinfang Ma, Nanwei Tong

“…We finally included DR-related studies involving intensive glucose control with large sample size and long follow-up time, including five large and high-quality randomized clinical trials (RCTs): DCCT, UKPDS, ACCORD, AdRem, and VADT. …”
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Effect of Vaginal Cream with the Combination of Honey, Olive, and Propolis on the Symptoms of Uterine Cervicitis Symptoms in Women: A Double-Blind Randomized Controlled Clinical Trial Study by Hamideh Parsapour, Arezoo Shayan, Mehrnoosh Hosseinpoor, Seyedeh Zahra Masoumi, Farideh Kazemi, Shirin Moradkhani, Seyed Mohammad Hossein Oliaei, Zeinab Assareh, Mohammad Kazem Rashidi

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Health-Related Quality-of-Life Utility Values in Adults With Late-Onset Pompe Disease: Analyses of EQ-5D Data From the PROPEL Clinical Trial by Alison Griffiths, Simon Shohet, Neil Johnson, Alasdair MacCulloch

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Achillea millefolium capsule improved liver enzymes and lipid profile compared to placebo in patients with type 2 diabetes: a double-blind randomized clinical trial by Shole Daneshvar-Ghahfarokhi, Hassan Ahmadinia, Tabandeh Sadeghi, Elham Basirat, Vahid Mohammadi-Shahrokhi

“…Trial registration Iranian Registry of Clinical Trials IRCT20230612058459N1 Registered on 2023–06–24.…”
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Efficacy of Knee Taping in addition to a Supervised Exercise Protocol to Manage Pain and Functional Status in Individuals with Patellofemoral Osteoarthritis: A Randomized, Controlled Clinical Trial by Mudasir Nazar Shah, Mohammad Abu Shaphe, Mohammed Qasheesh, Mohammad Kashif Reza, Ahmad H. Alghadir, Amir Iqbal, Priyadarshani Bhat

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Effects of prophylactic antibiotic administration and antibiotic timing on culture results and clinical outcomes of paediatric musculoskeletal infection: a protocol for a randomised controlled clinical trial by Chao You, Yibiao Zhou, Zhiyong Liu, Chao Deng, Yongjie Xia, Dechao Wu, Liangfu Xie, Bing E, Jingming Han

“…The aim of the present study is to investigate the effects of prophylactic antibiotic administration and the timing of antibiotic administration on culture sensitivity and clinical outcomes of paediatric MSI.Methods and analysis A randomised controlled clinical trial will be carried out. Individuals aged 0–18 years with a diagnosis of MSI will be screened and evaluated at the Shenzhen Children’s Hospital. …”
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Correction: Efficacy and safety of jaktinib hydrochloride tablets in active axial spondyloarthritis: a multicentre, randomised, double-blind, placebo-controlled phase II clinical trial

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Correction: Human-Prosthetic Interaction (HumanIT): A study protocol for a clinical trial evaluating brain neuroplasticity and functional performance after lower limb loss. by Elke Lathouwers, Bruno Tassignon, Alexandre Maricot, Felipe Gomez, Fanny Delquignies, Claire Cherelle, Ahmed Radwan, Maarten Naeyaert, Hubert Raeymaekers, Peter Van Schuerbeek, Stefan Sunaert, Johan De Mey, Kevin De Pauw

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Effect of remote ischemic preconditioning on perioperative neurocognitive disorder in elderly patients undergoing major surgery and associated genetic variant analysis: a randomized clinical trial by Feifei Xu, Tingting Liu, Huiqing Liu, Jiao Deng, Shan He, Zhihong Lu, Haopeng Zhang, Hailong Dong

“…Trial registration. Chinese Clinical Trial Registry (ChiCTR2000035020(07/28/2020)).…”
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