Influence of urokinase gene-knockout in C57BL/6-PlautmI. IBugThisPlau6FDhu/GFDhu mice on growth factors in malignant melanoma by E. M. Frantsiyants, I. V. Kaplieva, I. V. Neskubina, V. A. Bandovkina, L. K. Trepitaki, E. I. Surikova, N. D. Cheryarina, L. A. Nemashkalova, N. S. Lesovaya

“…Interestingly, a significant, although lesser than in mice with a normal genotype, accumulation of VEGFA in melanoma tissues was observed: in males – in tumors by 44.9 times, in perifocal tissues by 6.8 times, in the skin by 2.4 times; in females – in tumors by 5.6 times, in perifocal tissues by 2.6 times, in the skin by 3.3 times, compared to the corresponding intact controls, due to the probable involvement of the uPA receptor (uPAR) in the implementation of VEGF-induced processes.Conclusion. Changing the activity of a system of some growth factors, uPA gene-knockout modifies melanoma metabolism by inhibiting its growth and eliminating or reducing its metastatic activity.…”
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Leer rápido no siempre es igual a comprender: Examinando la relación entre velocidad y comprensión/Reading Fast is not always the same as Understanding: Examining the Relationship... by Gabriela Silva-Maceda, Silvia Romero-Contreras

“…Los resultados son interpretados en el contexto de la literatura existente. English A change in the way Reading is evaluated in Mexico in primary education has been the introduction of measuring reading speed in students. …”
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Clinical experience with heparin-containing eye ointment for dry eye by D.M. Safonova, A.O. Root, V.D. Yartsev, M.N. Narbut

“…Narbut — Junior Research Associate of the Refractive Changes Department.<br> Scientific Research Institute of Eye Diseases. 11a, Rossolimo st., Moscow, 119021, Russian Federation.…”
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Potential public health impacts of gonorrhea vaccination programmes under declining incidences: A modeling study. by Lin Geng, Lilith K Whittles, Borame L Dickens, Martin T W Chio, Yihao Chen, Rayner Kay Jin Tan, Azra Ghani, Jue Tao Lim

“…We further examined how altering (5) VoA and (6) VoD strategies changed if the strategies only targeted high risk groups (VoA(H),VoD(H)). …”
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Economic-productive analysis of a mixed cattle-bubaline model mixed model in the Northern region of Corrientes Province in Argentina by Pablo Maldonado-Vargas, Vanesa Guadalupe Mierke, Liliana Laura Pellerano, Guillermo Sebastián Grimaldi, Orlando Alberto Álvarez, Natalia Mercedes Vallejos, Margarita Rosa Itatí Romero, Francisco Daniel Romero, Alexis Sebastián Bandeo, Gonzalo Enrique Tuñón, José Luis Konrad

“…In the context of climate change, the global increase in droughts and floods and price volatility constitute a real challenge. …”
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La poésie lyrique, un outil d’unification linguistique et politique by Anne-Marie Le Baillif

“…Ronsard’s politic works in connection with the poets of the period change not only the language but also the way of thinking as it was the first step to centralism, which was the aims of the French kings. …”
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Implementing regional blue economy research and innovation strategies: a case study for the Black Sea by Baris Salihoglu, Baris Salihoglu, Mustafa Yücel, Pinar Uygurer, Ezgi Şahin Yücel, Evangelos Papathanassiou, Devrim Tezcan, Adrian Stanica, Irina Stanciu, Snejana Petrova Moncheva, Nina Dzhembekova, Kremena Blagovestova Stefanova, Viktor Komorin, Tudor Castravet, Kakhaber Bilashvili, Valerian Melikidze, Mamuka Gvilava, Salome Kobaidze

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Developing a multivariate drought index to assess drought characteristics based on the SWAT-Copula method in the Poyang Lake basin, China by Liping Guo, Fusheng Chen, Bin Wang, De Li Liu, Xiulong Chen, Hongsheng Huang, Hua Bai, Kaitao Liao, Zhiming Xia, Keyu Xiang, Linchao Li, Taihui Zheng, Qiang Yu

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Epidemiological aspects of nephrolithiasis and chronic diseases of the cardiovascular system combination by R. V. Royuk, S. K. Yarovoy, N. A. Guseva, Sh. L. Voskanyan, V. V. Royuk, D. B. Rodin

“…The presence chronic cardiovascular diseases (CVD), especially complicated by congestive heart failure in patients with first time revealed nephrolithiasis, implies changes in the algorithms of metaphylactic of nephrolithiasis (regime of water loads, selection of diuretics and anticoagulants).…”
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Five-Year Prospective Follow-Up of Patients with Hepatitis C Virus Infection Treated with Direct-Acting Antiviral Agents by Zhang Y, Xia H, Fan L, Jiang L, Yang B, Wang F

“…The annualized incidence rates (AIRs), cumulative incidence rates of adverse events and risk factors were investigated. Changes in liver stiffness measurement (LSM), aspartate aminotransferase-to-platelet ratio index (APRI) score, fibrosis-4 (FIB-4) index, as well as the albumin-bilirubin (ALBI) scores were also documented.Results: A total of 862 individuals were followed up for 4.86 (P25, P75; 4.48, 5.48) years. …”
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Knowledge, Attitude, and Practice of Pediculus Capitis Prevention and Control and Their Predictors among Schoolchildren in Woreta Town, Northwest Ethiopia, 2018: A School-Based Cro... by Henok Dagne, Awel Aba Biya, Amanuel Tirfie, Walelegn Worku Yallew, Zewudu Andualem, Baye Dagnew

“…The knowledge, attitude, and practice of schoolchildren regarding pediculus capitis prevention and control were not satisfactory. To bring change, intensive efforts on factors associated with the knowledge, attitude, and practice should be encouraged.…”
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CAMELS-IND: hydrometeorological time series and catchment attributes for 228 catchments in Peninsular India by N. K. Mangukiya, K. B. Kumar, P. Dey, S. Sharma, V. Bejagam, P. P. Mujumdar, P. P. Mujumdar, A. Sharma, A. Sharma

“…We envision that CAMELS-IND will provide a strong foundation for a community-led effort toward gaining new hydrological insights from hydrologically distinct Indian catchments and solving pertinent issues related to water management, quantification and risk assessment of hydrologic extremes, unraveling regional-scale hydrologic functioning, and climate change impact assessment of catchments across India. …”
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1-(5-ACETYL-3-METHYL-6-PHENYL-5H-[1,2,4]TRIAZOLO [3,4-b][1,3,4]THIADIAZIN-7-YL)-ETHANONE: DOSE-DEPENDENCE OF ANALGESIC EFFECT, LACK OF OPIOIDERGIC MECHANISM OF ACTION, EFFECT ON BE... by Andriy Koval, Sergiy Shtrygol

“…This compound does not cause changes in the behavior of mice in the open field test and belongs to the IV toxicity class - low-toxic substances.…”
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Small RNA CjNC110 regulates the activated methyl cycle to enable optimal chicken colonization by Campylobacter jejuni by Brandon Ruddell, Alan Hassall, Orhan Sahin, Paul J. Plummer, Qijing Zhang, Amanda J. Kreuder

“…However, we demonstrated that W7∆CjNC110 does not change chicken colonization levels compared to W7 wild type, directly contrasting IA3902∆CjNC110, which had decreased colonization ability. …”
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Digital Home-Based Self-Monitoring System for People with Heart Failure: Protocol for Development of SmartHeart and Evaluation of Feasibility and Acceptability by Ralph Maddison, Rebecca Nourse, Reza Daryabeygikhotbehsara, Teketo Kassaw Tegegne, Paul Jansons, Jonathan Charles Rawstorn, John Atherton, Andrea Driscoll, Brian Oldenburg, Rajesh Vasa, Vassilis Kostakos, Tilman Dingler, Gavin Abbott, Paul Scuffham, Jo-Anne Elizabeth Manski-Nankervis, Dominika Kwasnicka, Finn Kensing, Sheikh Mohammed Shariful Islam, Anthony Maeder, Yuxin Zhang

“…The primary outcome will be a description of the study's feasibility (recruitment, attrition, engagement, and changes in self-care). ResultsThe SmartHeart study started in January 2021 on procurement of funding. …”
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The pattem of the conquest of the Polabian Slavs and Western Baltic lands from the point of view of Christianization of the Baltic tribes by Marius Ščavinskas

“…However, in Lithuania there was the encounter with the state, not with the tribal society, and this aspect undoubtedly changes everything. …”
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Immune responses in children with secondary infection of mycoplasma pneumoniae after COVID-19: focus on eosinophils and IgE by Pingping Wang, Jin Yao, Yaqiong Li, Zhanjun Zhang, Ruiling Zhang, Shouting Lu, Meixia Sun, Xiaorong Huang

“…Objective This study aims to explore the characteristics of immune response in children with SARS-CoV-2 infection and Mycoplasma pneumoniae infection, focusing on the changes in immune indicators such as eosinophils (EOS), immunoglobulin E (IgE), interleukin-6 (IL-6), C-reactive protein (CRP), and procalcitonin (PCT). …”
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4-Octyl itaconate inhibits synovitis in the mouse model of post-traumatic osteoarthritis and alleviates pain by Yu-Zhen Tang, Wan Chen, Bao-Yun Xu, Gang He, Xiu-Cheng Fan, Kang-Lai Tang

“…Purpose: To investigate the pathological changes of the synovium in mice with post-traumatic osteoarthritis (PTOA) treated with 4-octyl itaconate (4-OI) and evaluate the therapeutic effects of 4-OI. …”
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Fu Tu Sheng Jin Rehabilitation Formula Mitigate Airway Inflammation, Mucus Secretion and Immune Dysfunction Induced by SARS-CoV-2 Spike Protein by Wang BH, Yu KY, Zhang XN, Sun XH, Tang LL, Shi XL

“…Observe the pathological changes in lung tissues, expression of inflammatory factors, and mucins in different groups of mice using HE and PAS staining methods, as well as ELISA and RT-qPCR. …”
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Massive permafrost rock slide under a warming polythermal glacier deciphered through mechanical modeling (Bliggspitze, Austria) by F. Pfluger, S. Weber, S. Weber, J. Steinhauser, C. Zangerl, C. Fey, J. Fürst, M. Krautblatter

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